Relevant Keywords Research Articles

Effects of mind-body exercise on individuals with ADHD: a systematic review and meta-analysis

ObjectiveTo explore the effects of mind-body exercise (MBE) on ADHD through a systematic review and meta-analysis.MethodsAfter identifying relevant search keywords based on the study’s technical terminology, research articles were retrieved from five databases. Two researchers independently screened the results to select studies that met the inclusion criteria. A random-effects model was used to conduct a meta-analysis on the included studies.ResultsThe findings indicate that MBE interventions significantly improved attention in individuals with ADHD [SMD=-0.97, 95% CI (-1.56, -0.39), P < 0.05]. However, the meta-analysis found no evidence that MBE improved executive function, emotional issues, or hyperactivity/impulsivity in ADHD patients.ConclusionsMBE is beneficial for attention improvement in ADHD patients. However, further evidence is needed to support its efficacy as an adjunctive treatment for other symptoms.Systematic review registrationhttps://www.crd.york.ac.uk/prospero, identifier CRD42023447510.

Improving Safety and Reducing Clinical Errors in Anesthesia: Which Checklist Is Your Choice?

The safety of the beating heart is a health service that means the absence of clinical errors during the implementation of health care. The period of anesthesia is identified as one of the most critical phases for patients requiring general anesthesia, carrying the potential for critical clinical errors that may have irreversible consequences. This study's main objective was to conduct a concise assessment of the anesthesia checklists utilized to enhance patient safety during general anesthesia procedures. To accomplish this, a comprehensive search was conducted using relevant keywords spanning from 1990 to 2023 across databases including PubMed, Springer, Google Scholar, Web of Science, Scopus, online libraries, and the Cochrane library. Initially, 188 studies were identified at the outset of the research, and among these, 13 studies that focused on the development of checklists for anesthesia safety were scrutinized. Included articles were reviewed separately and divided into 3 categories; Specific vs. Generalized Scope, Single-Stage vs. Multi-Stage, Single-Factor vs. Multi-Factor. According to the findings from these studies, the systematic and proper utilization of all available checklists can contribute to improved safety. However, due to the specialization of surgical procedures and the increasing emphasis on patient safety over the past decade, there has been a shift in the compilation of anesthesia checklists from being broad and general to becoming specific, transitioning from single-stage to multi-stage, and evolving from single-factor to multi-factor checklists.

HPV Vaccine Hesitancy and Uptake: A Conceptual Analysis Using Rodgers' Evolutionary Approach.

This study examines the factors contributing to HPV vaccine hesitancy using Rodgers's evolutionary concept analysis, focusing on the impact of uncertainties about the vaccine on HPV-related diseases despite its availability. Rodgers's evolutionary concept analysis was applied to explore factors leading to HPV vaccine hesitancy. The analysis included studies published in English over the past 5 years. Exclusions were studies older than 5 years, non-English publications, and those focusing on other vaccines. A comprehensive literature review was conducted using key databases such as PsycINFO, CINAHL, MEDLINE, and PubMed. Relevant keywords included 'HPV' and 'vaccine hesitancy' to ensure thoroughness. Studies were selected based on their relevance to HPV vaccine hesitancy. Factors contributing to hesitancy were analysed, focusing on antecedents, attributes, and consequences. The analysis identified key antecedents to HPV vaccine hesitancy, including false cultural beliefs, educational level, knowledge, and vaccine availability. Additional factors were insurance/income, perceived risk, and decision-making processes. Key attributes impacting hesitancy included media coverage, environmental and community influences, social factors, trust in healthcare systems, efficacy rates, and safety concerns. The consequences of hesitancy were reduced vaccine uptake, increased HPV-related diseases, and the spread of misinformation. The study highlights the complex interplay of factors contributing to HPV vaccine hesitancy. Understanding these factors is crucial for addressing the challenges posed by vaccine hesitancy and developing effective interventions. Insights from this analysis can guide public health strategies aimed at improving vaccine uptake and reducing HPV-related diseases. Targeted interventions can address misinformation and enhance trust in vaccines, ultimately leading to better public health outcomes. This concept analysis was conducted without the involvement of patients, service users, caregivers, or members of the public.

Systematic Review of Surgical Success, Complications, Revision Rates, Radiation Dosage, and Operative Time of 3D-Navigated vs. Non-Navigated Spinal Procedures.

3D navigation offers real-time guidance in surgery. However, there is limited and inconsistent data regarding the usability, safety, and efficacy. To address gaps in knowledge about 3D navigation in spinal surgery, we conducted a comprehensive review of success rates, complications, revisions, radiation exposure, and operative time associated with FDA-approved 3D surgical navigation tools. This study adhered to PRISMA guidelines and used a protocol registered on PROSPERO (CRD42023404554). Ovid MEDLINE, Embase, and Cochrane Central Register of Controlled Trials databases were searched using relevant keywords for 3D surgical navigation and spinal procedures from 1946 to March 02, 2023. Two independent reviewers assessed the studies using inclusion/exclusion criteria and risk of bias tools. Statistical analyses included one-way ANOVA, weighted-mean difference, and unpaired t-tests with Welch's correction for associations and comparisons between groups, respectively. Of the total 11,324 studies identified and 7,198 screened, 62 studies totaling 3,170 adult patients were included in this comprehensive review. Complication and surgical success rates have remained constant since 2004, with overall rates of 5.5% and 94.0%, respectively. When segmented by spinal region, complication rates may be moderately positively correlated with frequency of cervical and thoracic procedures (r = 0.25, p = 0.68). The most commonly reported complication was pedicle screw malposition or breach. A subset of 20 studies, totaling 1,554 patients, compared the performance of 3D navigation to 2D fluoroscopy or freehand navigation. There was a significant difference of 6.53% between surgical success rates of the 3D-navigated and control groups (p = 0.03). However, there was no significant difference in radiation exposure or operative time. 3D navigation in spinal procedures has higher surgical success rates than 2D fluoroscopy and freehand navigation. Included studies exhibited varying limitations, including no patient follow-up (n = 1), less than 10 patients (n = 6), various types of spinal disorders (n = 1), and varying comorbidities among participants (n = 2). Improving 3D navigation tools remains imperative to decrease operative time and radiation exposure.

Outdoor thermal comfort in face of the urban heat island effect: innovative solutions for cooler cities; a case study in Souk Ahras city

This study investigates the relationship between the urban heat island effect and outdoor thermal comfort through a bibliometric analysis of relevant keywords, highlighting their strong connection. The analysis highlights how trees improve urban microclimates and enhance outdoor comfort by integrating them into public space design. The research in Souk Ahras city investigates two public spaces, using in situ measurements and the Rayman model to analyze thermal indices (SVF, Tmrt, and PET) based on climatic data and urban geometry collected on a hot summer day. The findings show that trees at each intervention site reduce average daily air temperature by 0.43°C to 1.043°C, lower mean radiant temperature (Tmrt) by 1°C to 1.2°C, and decrease physiological equivalent temperature (PET) by 0.16°C to 1.58°C. Trees also reduce the sky view factor, highlighting their role in improving outdoor thermal comfort through shading and evapotranspiration. These results confirm that integrating trees into public space design effectively enhances outdoor thermal comfort and urban microclimates during warmer seasons.

PEDESTRIAN SAFETY AND SECURITY FOR FEMALE USERS IN URBAN ALLEYS: A SYSTEMATIC REVIEW

The world's rapid urbanization has led to the emergence of hundreds of alleys between towering skyscrapers. Nowadays, there is numerous safety issues associated with urban alleys and people often associate these alleys with dirt, crime and fear. Consequently, using urban alleys hinders people-especially women-from obtaining basic essentials for safety. Numerous studies have indicated that women perceive cities differently than males and they typically feel more uneasy in public places. The purpose of this article is to investigate strategies and features that can enhance the safety of female pedestrians in urban alleys. After thoroughly examining the Web of Science and Scopus databases, 45 publications were identified. These articles were selected by incorporating keywords such as urban alleys, safety, female users and relevant keywords. The review encompasses information on data collection methods, sample strategies, data analysis and outcome analysis. The study reveals that physical factors, social, psychological and crime prevention factors also influence how women use urban alleys. Nevertheless, women's perceptions of the safety of urban alleys are significantly influenced by physical factors. Ultimately, these findings provide managers, planners and urban designers with valuable insights to establish a foundation for safer urban settings.

MOBILE LEARNING APPLICATIONS AND CHANGES IN MATERNAL BEHAVIOR IN THE PROVISION OF FOOD FOR CHILDREN: SYSTEMATIC REVIEW

Background: Nutritional problems among children, especially in developing countries, remain a significant concern. Stunting, underweight, and malnutrition are prevalent due to inadequate dietary intake and poor maternal education. Mobile learning (m-learning) applications have emerged as potential tools to enhance maternal knowledge and improve child nutrition. This study systematically reviews existing literature to assess the impact of m-learning applications on changing maternal behavior in the provision of food for children.Method: This systematic literature review follows the PRISMA guidelines. The review was conducted in August 2024, covering studies published from 2014 to 2024. Databases including Scopus, PubMed, and Crossref were searched using relevant keywords. A total of 348 articles were identified, with 30 meeting the inclusion criteria for final analysis. The selected studies were analyzed to evaluate the effectiveness of m-learning applications in altering maternal behavior related to food provision.Results: The review indicates that m-learning applications significantly enhance maternal knowledge and positively influence food provision behaviors. However, the effectiveness of these applications is influenced by factors such as socio-economic status, cultural context, and the usability of the application. Personalized feedback, community support, and interactive features within the applications are crucial for achieving behavior change.Conclusions: M-learning applications hold substantial potential for improving maternal behavior in food provision, thereby enhancing child nutrition. Future developments should focus on culturally relevant content, user-friendly interfaces, and integrating community support mechanisms to maximize the effectiveness of these interventions.

Impact of haptic simulator in prosthodontics training during preclinic dental education: a systematic review protocol

Background Prosthodontics significantly impacts oral health-related quality of life, especially oral comfort, functions, aesthetics, and overall well-being. This discipline is grounded in a solid academic and evidence-based understanding of fundamental principles for managing dental diseases and aims to restore the health of teeth and supporting tissues and compensate missing ones. Dental education is evolving quickly with the rise of digital dentistry, especially in prosthodontics. Integrating augmented reality simulations and haptic feedback has significantly advanced this transformation. This systematic review protocol intends to determine the effectiveness of haptic simulators in prosthodontics training during preclinical dental education. Methods An exhaustive search strategy will be employed, exploring PubMed, Scopus, EBSCO, Web of Science and Cochrane Central to select relevant studies, thereby enhancing the robustness of the review findings. Boolean operators (AND,OR) were utilized to assemble MeSH terms and relevant keywords. Titles and abstracts screening to identify studies that satisfy the eligibility criteria was followed by the quality and risk of bias assessment for the selected studies, via the Cochrane Collaboration’s tool and the Newcastle-Ottawa Scale (NOS). Data will be collected via standard form. Reviewers disagreement will be solved throughout debate, or by referring to a third opinion. This protocol will adhere the recommendations appointed by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Discussion The outcomes of this systematic review are highly significant for dental education exploring the importance of enhancing haptic simulation during preclinic prosthetic training. Recognizing the strengths and weaknesses of virtual reality (VR) in relation to traditional preclinical training methods is crucial for developing effective educational strategies. This understanding can lead to enhanced training outcomes and increased student satisfaction, which in turn contributes to improved quality of clinical prosthetic services. Systematic review registration PROSPERO: CRD42024603681 (Registered on 30/10/2024).

A decade of operations strategy: research issues and future research directions

Purpose This study aims to systematically review the literature on operations strategy to understand its role in fostering competitive advantage. The literature on operations strategy was summarized using bibliometric analysis, network analysis and content analysis techniques. The bibliometric approaches analyzed 1,070 articles published between January 2013 and December 2023. Additionally, it is supplemented through content analysis by analyzing 60 selected articles in depth. The review identified six major research themes in operations strategy: impact of supply chain integration on operational performance, outsourcing and resource-based view, lean strategy, service operations strategy, operations capabilities and responsive supply chain strategy. The review offers a comprehensive overview of current research and highlights potential areas for future exploration, providing valuable guidance for scholars and practitioners in operations strategy. Also, the review provides insights for operations managers that can be applied to develop effective strategies across various industrial contexts. Design/methodology/approach The main objective of a literature review is to analyze the body of existing knowledge, identify possible research gaps and propose future research avenues (Tranfield et al., 2003). Searching for relevant keywords, discovering pertinent information and then completing the analysis are expected in systematic literature reviews. Tranfield et al. (2003) have provided the guidelines to conduct the literature review in a systematic way, which scholars in the business and management domains increasingly adopt. It consists of three stages as follows: planning the review; conducting the review; and reporting and dissemination. The present study uses these guidelines to organize the literature on operations strategy. Findings This work provides several theoretical and managerial implications by offering a thorough and methodical understanding of the area. It contributes to the corpus of knowledge that provides a frame of reference based on an insightful synthesis of the prior study. It aims to identify future research avenues in the domain of operations strategy. Several research avenues are identified by carefully analyzing the available literature and conducting a robust bibliometric approach combined with network and content analysis techniques. Thus, the current study will be a valuable resource for future scholars interested in learning about and examining this area. Research limitations/implications Continuous research for improvement in the existing system or practice has been the fundamental nature of human beings. Hence, it is pertinent to identify future research avenues for the researchers interested in the area. Despite the extensive studies on operations strategy, certain areas require more investigation. As per the analysis of the literature search of 1,070 articles published in the area, the author suggests future scholars explore the following research avenues: need for conceptual and mixed–method studies; cross-country comparison and generalization; integration with Industry 4.0 technologies; integration with the triple bottom line; and aligning with circular economy. Practical implications A need is created to generate a pathway of aligning operations strategy with the principles of circular economy, requiring future research to address its fundamentals. Potential research questions that could be explored are as follows: How can companies align operations strategy with circular economy principles to minimize waste and improve resource efficiency? How does adopting circular economy practices impact supply chain design and operations strategy? What role do innovation and technology play in integrating circular economy principles into operations strategy? Social implications The proposed research avenues will provide adequate information to operations managers about areas of attention that would fully leverage operations strategy and provide the firm with a competitive advantage. Moreover, integrating their outcomes with Industry 4.0 technologies, particularly emerging technologies such as artificial intelligence, blockchain and the Internet of Things can provide a new direction for operations managers. Furthermore, operations performance can make or break the organization. Performance is not a simple or easy concern; it is multi-faceted in the sense that a single measure can never comprehensively represent it. Several measures will always be needed to evaluate the holistic performance of a firm. Originality/value This work provides several theoretical and managerial implications by offering a thorough and methodical understanding of the area. It contributes to the corpus of knowledge that provides a frame of reference based on an insightful synthesis of the prior study. It aims to identify future research avenues in the domain of operations strategy. Several research avenues are identified by carefully analyzing the available literature and conducting a robust bibliometric approach combined with network and content analysis techniques. Thus, the current study will be a valuable resource for future scholars interested in learning about and examining this area.

Exploring ChatGPT in clinical inquiry: a scoping review of characteristics, applications, challenges, and evaluation.

Recent advancements in generative AI, exemplified by ChatGPT, hold promise for healthcare applications such as decision-making support, education, and patient engagement. However, rigorous evaluation is crucial to ensure reliability and safety in clinical contexts. This scoping review explores ChatGPT's role in clinical inquiry, focusing on its characteristics, applications, challenges, and evaluation. This review, conducted in 2023, followed PRISMA-ScR guidelines (Supplemental Digital Content 1, http://links.lww.com/MS9/A636). Searches were performed across PubMed, Scopus, IEEE, Web of Science, Cochrane, and Google Scholar using relevant keywords. The review explored ChatGPT's effectiveness in various medical domains, evaluation methods, target users, and comparisons with other AI models. Data synthesis and analysis incorporated both quantitative and qualitative approaches. Analysis of 41 academic studies highlights ChatGPT's potential in medical education, patient care, and decision support, though performance varies by medical specialty and linguistic context. GPT-3.5, frequently referenced in 26 studies, demonstrated adaptability across diverse scenarios. Challenges include limited access to official answer keys and inconsistent performance, underscoring the need for ongoing refinement. Evaluation methods, including expert comparisons and statistical analyses, provided significant insights into ChatGPT's efficacy. The identification of target users, such as medical educators and nonexpert clinicians, illustrates its broad applicability. ChatGPT shows significant potential in enhancing clinical practice and medical education. Nevertheless, continuous refinement is essential for its successful integration into healthcare, aiming to improve patient care outcomes, and address the evolving needs of the medical community.

Legal and Social Implications of Cryptocurrency Adoption in Developing Countries

This study aims to analyze the legal and social implications of cryptocurrency adoption in developing countries. This study adopts a holistic approach that integrates legal, social, and economic analysis to provide a more comprehensive understanding. This study uses a qualitative method with a literature review approach. Data were collected through a systematic search of academic databases using relevant keywords. Thematic analysis was conducted to identify key themes related to cryptocurrency adoption in developing countries. Triangulation of data sources and consideration of geographical context were conducted to ensure the validity of the results. The results show that cryptocurrency adoption in developing countries has significant potential but also presents complex challenges. Some of the key findings include: cryptocurrency has the potential to increase financial inclusion for the unbanked population; developing countries face regulatory dilemmas in adopting cryptocurrency; widespread adoption of cryptocurrency can affect macroeconomic stability; cryptocurrency shows the potential to revolutionize the remittance sector; limited technological infrastructure is a major barrier to adoption; cryptocurrency adoption has diverse social implications, including the risk of widening the digital divide; lack of consumer protection mechanisms is a major concern; international collaboration is essential in addressing adoption challenges; low financial and digital literacy are significant barriers; and cryptocurrency adoption raises environmental concerns related to energy use.

Analysis Research Trends on Barriers to Halal Label Registration in Indonesia: A Literature Review

This research investigates research trends related to obstacles in registering halal labels in Indonesia. This research is a literature review. The analysis uses a systematic literature review method. Data sources include journal articles, research reports and government publications from 2019 to 2024. A literature search was carried out through major academic databases with relevant keywords, followed by a selection and synthesis process of the data obtained. The search is carried out with the help of the Publish or Perish program. Through an in-depth literature review, this study identifies the main factors that hinder the halal registration process and evaluates their impact on various stakeholders. The obstacles identified include costs, bureaucratic complexity, awareness and understanding of business actors, and the capacity of halal certification institutions. These findings offer insights that can help stakeholders formulate effective interventions to increase the number of halal label registrations, which is crucial for meeting domestic and global market needs and increasing the competitiveness of Indonesian products.

Narratives Driven Bull Market: The Indian Stock Market 2020-2024

Abstract: Narratives play a key role in shaping the opinions of people. Advent of social media has accentuated the importance of narratives in economic and financial decisions. Narrative is a piece of information gone widespread due its acceptability and relevance to the masses. Frenzy during bull markets is usually associated with a flow of narratives building momentum. Objectives of this study is to examine the relationship between the bull market in the Indian Stocks during 2020-24 and the socio-economic narratives in circulation, effects of sustained favourable narratives during negative socio-economic event and quantification of the relationship. Only secondary data is used for this study. For collection of data, individual phrase, summarizing each narrative and relevant keywords for the phrase are used to make the search relevant and get precise textual count. Multiple regression model is used for this study to test the existence of relationship between Nifty 50 Index and narratives. The study indicates that the rise in Indian stocks during 2020-24 is explained by the independent variables - ‘Atmanirbhar Bharat’ and ‘India, Emerging Manufacturing Powerhouse’, individually and collectively

FISIOTERAPIA NO PÓS CIRÚRGICO DE MASTECTOMIA: UMA REVISÃO DE LITERATURA

Introduction: Cancer is a growing global concern, affecting nearly 40% of people in North America and more than one million in Australia. Breast cancer is the second most common cancer in the world, with significant rates also in Brazil, especially in the Southeast and South regions. Early diagnosis is crucial, influenced by factors such as gynecological history and heredity. After treatment, patients face significant side effects, including pain and loss of functional capacity. Oncology physiotherapy plays a vital role in rehabilitation, with techniques such as complex decompression physiotherapy and early exercise proving beneficial. New approaches, such as combining botulinum toxin A with physical therapy, offer hope in post- treatment management. Background: The increasing prevalence of cancer highlights the need to integrate rehabilitation with cancer care to minimize patient suffering. The comprehensive approach is essential for breast cancer, with post-treatment rehabilitation being crucial for managing complications and improving quality of life. Physiotherapy plays an essential role, with techniques such as complex decompression physiotherapy and combinations of therapies emerging as promising. These multidisciplinary and personalized approaches aim to improve patients' physical and emotional well-being. Objectives: To investigate the role of physical therapy interventions in breast cancer rehabilitation, identifying studies, analyzing procedures, summarizing findings, assessing quality, and formulating recommendations for future research. Method: This comprehensive review explores the role of physical therapy in the treatment of breast cancer by analyzing 16 clinical trials selected after strict application of exclusion criteria. The objective is to understand the effectiveness of physical therapy interventions in improving the quality of life of patients. The search focuses on articles obtained from academic sources and uses relevant keywords to optimize the selection of studies. Results and Discussion: Recent studies on physical therapy interventions in the treatment of breast cancer highlight a range of approaches and outcomes. While some interventions, such as botulinum toxin A infiltration, have not shown efficacy, others, such as kinesiotherapy, have demonstrated improvements in quality of life. The research highlights the importance of updating physical therapy practices to improve clinical outcomes and quality of life for patients.

Battlefield mechanical ventilation and extracorporeal membrane oxygenation: A scoping review.

Casualties of military conflicts suffer a multitude of injuries, and recent research has documented a significant number develop acute respiratory distress syndrome (ARDS). The present study undertakes a scoping review of research on the treatment of ARDS in combat casualties near the battlefield. We review the extent of the current ARDS care, from intubation and mechanical ventilation (MV) to the use of extracorporeal membrane oxygenation (ECMO), and how the respective echelons of care across the Military Health System (MHS) are involved in the care of these patients. Online databases were used to identify article published 1988-2022, from which we selected 112 publications from various countries including the USA, UK, Germany, Italy, and India that used military relevant keywords (i.e., battlefield, combat, deployed, military trauma), in the titles or abstract in conjunction with the MeSH descriptors for battlefield respiratory failure, and MV or ECMO. Mechanical ventilation and ECMO have clearly moved forward with progressions in technologies and now are routinely used and are well documented in the prehospital setting and during aeromedical transport. Overview of the MHS and descriptive analysis of battlefield casualties are well represented in the literature. There are multiple publications on airway management on the battlefield and innumerable regarding the somewhat comparable civilian prehospital trauma airway management. While there is an abundance of publications on MV in the prehospital and combat environments, there are few case examples of the use of ECMO on the battlefield. Although MV may be required for many combat casualties, airway management failure remains the second leading cause of preventable death on the battlefield.

Assessing The Impact Of Surgical Approaches On Total HIP Replace-ment Outcomes: A Systematic Review

Total hip replacement is one of the most common and effective orthopedic surgical procedures to reduce pain and improve hip function in patients with severe conditions. This procedure has undergone many advances in the past few decades. However, there is debate among surgeons about which surgical approach is the most optimal to apply. This study aims to systematically assess and compare the outcomes of different surgical approaches in total hip replacement (THR) procedures. The method used in this study was a systematic literature review, in which literature was searched through academic databases such as PubMed, Scopus, and Google Scholar using relevant keywords. The collected data were then analyzed through three stages, namely data reduction, data presentation, and conclusion drawing. The results of this study show that each surgical method for total hip replacement has different advantages and disadvantages. The choice of surgical approach should be tailored to each patient's specific condition. Based on a review of the available literature, the anterior approach is often considered superior to the other approaches. The advantages include less surgical trauma, better postoperative pain reduction and a faster rehabilitation process. The anterior approach is considered safe, reliable and effective, and results in lower pain levels compared to other methods

Poverty reduction and the sustainable development goals: a bibliometric study focused on the Global South

ABSTRACT This research undertakes a bibliometric examination of the existing literature addressing the relationship between poverty and sustainability development, summarising available studies. Using relevant keywords, we identified 920 peer-reviewed articles from the Scopus database, spanning the period from 2015 to 2024. Employing the Visualisation of Similarity Viewer (VOSviewer) for this bibliometric analysis, we categorised prominent publications, noteworthy journals, and contributing institutions. Furthermore, our review uncovered a clear pattern in research, suggesting a lack of recognition regarding the impact of sustainable development on reducing poverty levels in countries of the Global South. In terms of contributions, this study delineates five primary thematic clusters that elucidate the ways in which sustainability development reduces poverty. Through the application of text-mining analysis, our research establishes connections between specific environmental terms and the recent surge in global poverty.

Tranexamic Acid in Liposuction: A Systematic Review of Literature and Meta-Analysis.

Tranexamic acid (TXA) is increasingly employed in plastic surgery to reduce perioperative hemorrhage. This systematic review assesses TXA's impact on blood loss, bruising, and fat graft survival following liposuction. A PRISMA-compliant systematic review was conducted. PubMed, Google Scholar, and Cochrane Library were searched using relevant keywords. Adult liposuction patients, receiving "intravenous TXA", "topical TXA", or "placebo", were categorized into "treatment" or "control" groups. Randomized controlled trials, prospective or retrospective cohort studies, and case-control studies were included, while uncontrolled observational studies, systematic reviews, letters, animal studies, and conference abstracts were excluded. Data on blood loss and bruises severity were synthetized into Excel spreadsheets. Study quality was independently assessed by two reviewers. Statistical analysis was accomplished employing forest plots for Hedge's G effect sizes and standardized mean differences, I2 heterogeneity, and publication bias using Egger's regressions and trim-and-fill funnel plots. Seven studies encompassing 457 patients were analyzed. Findings suggest that intravenous and topical TXA may contribute to blood loss reduction and a potential decrease in bruises severity following liposuction. No thromboembolic or serious complications were reported, suggesting a favorable safety profile for its routine use. TXA's impact on fat graft survival remains unknown. This meta-analysis suggests that TXA might be beneficial in reducing blood loss and bruising after liposuction, but the results are not definitive due to study limitations. Larger randomized controlled trials with standardized protocols of TXA administration, and better-designed measurement instruments are needed to confirm these findings. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Efficacy of Acceptance and Commitment Therapy in Social Anxiety Disorder: A Systematic Review and Meta-analysis

Background: Acceptance and commitment therapy (ACT) is a novel third-wave therapy becoming popular in the management of various anxiety disorders. In this systematic review, we wish to gather the data that have been studied to determine the effectiveness of ACT in treating social anxiety disorder (SAD). Methods: This study followed standard systematic review guidelines and was registered with PROSPERO prior to undertaking the review. Databases, namely PubMed, PsycINFO, Ovid MEDLINE, and gray literature (ClinicalTrials.gov, BASE) with relevant keywords, were searched from inception to February 2024. Randomized controlled trials encompassing both clinical and nonclinical populations aged more than 10 years diagnosed with SAD were included. These trials compared ACT with wait list controls (n = 6) and cognitive behavioral therapy (n = 3). The primary outcome focused on the reduction of symptoms associated with social anxiety, while quality of life served as a secondary outcome. Measures of effect were determined through pre-test and post-test mean values, alongside their respective standard deviations. The random effect model was used to calculate pooled effect size. The quality of the included papers was assessed using Cochrane RoB-1. Covidence software was used for the initial selection of studies, and meta-analyses were performed using RevMan software. Results: From the initial 442 study records that were searched, finally 9 studies were included for the systematic review, of which 6 studies were found suitable for meta-analysis. The pooled estimate for studies comparing ACT with wait list found that the overall effect size for social anxiety symptoms was g = −1.28 (95% confidence interval of -1.88, -0.69) favoring ACT intervention significantly. Conclusion: This review found that ACT is efficacious in treating SAD. Most of the studies included were conducted in adolescent females. Varying ACT intervention modalities were incorporated, with the primary outcome assessed using a range of scales. The results of our meta-analysis should be interpreted with caution because of heterogeneity and smaller number of studies being included. ACT can be considered a psychotherapeutic option for the management of SAD.

Efficacy of submucosal administration of tramadol on acute pain following third molar surgery: a systematic review and meta-analysis.

This systematic review aimed to assess the effectiveness of submucosal tramadol injections in post-operative pain management following third molar surgical extraction. Databases, such as PubMed, Scopus, ScienceDirect, and Cochrane Library, were systematically searched using relevant keywords. Randomized clinical trials that met the inclusion criteria were assessed to determine the effectiveness of tramadol in managing acute post-operative pain following third molar surgery. In total, seven studies with participants of 18 and over following randomized placebo-controlled trials were considered for the analysis. A submucosal injection of 2 ml (50-100 mg) of tramadol adjacent to the impacted mandibular third molar effectively controlled pain for up to 6-24 h following surgery. Non-serious adverse events, such as nausea, vomiting, and headache, were reported in two studies. Meta-analysis (subgroup analysis) revealed heterogeneity among the studies, demonstrating variability in the results across the included studies. In addition, tramadol demonstrated a significant decrease in post-operative pain. Submucosal tramadol is an efficient, safe, and dependable method for reducing post-operative acute pain, particularly in the first 6 h following impacted third molar surgery. However, due to the observed heterogeneity in the research, there is need for cautious interpretation of the findings and potential limitations in the evidence base. To enhance the quality of evidence on this topic, we strongly recommend conducting new RCTs using established methodologies. Post operative pain following third molar surgeries is one of the common complications. Submucosal tramadol injections were found to be successful in reducing post extraction pain as well as other morbidities.