Relative Importance Of Demographics Research Articles

Determinants of Health-Related Quality of Life After ICU: Importance of Patient Demographics, Previous Comorbidity, and Severity of Illness.

ICU survivors frequently report reduced health-related quality of life, but the relative importance of preillness versus acute illness factors in survivor populations is not well understood. We aimed to explore health-related quality of life trajectories over 12 months following ICU discharge, patterns of improvement, or deterioration over this period, and the relative importance of demographics (age, gender, social deprivation), preexisting health (Functional Comorbidity Index), and acute illness severity (Acute Physiology and Chronic Health Evaluation II score, ventilation days) as determinants of health-related quality of life and relevant patient-reported symptoms during the year following ICU discharge. Nested cohort study within a previously published randomized controlled trial. Two ICUs in Edinburgh, Scotland. Adult ICU survivors (n = 240) who required more than 48 hours of mechanical ventilation. None. We prospectively collected data for age, gender, social deprivation (Scottish index of multiple deprivation), preexisting comorbidity (Functional Comorbidity Index), Acute Physiology and Chronic Health Evaluation II score, and days of mechanical ventilation. Health-related quality of life (Medical Outcomes Study Short Form version 2 Physical Component Score and Mental Component Score) and patient-reported symptoms (appetite, fatigue, pain, joint stiffness, and breathlessness) were measured at 3, 6, and 12 months. Mean Physical Component Score and Mental Component Score were reduced at all time points with minimal change between 3 and 12 months. In multivariable analysis, increasing pre-ICU comorbidity count was strongly associated with lower health-related quality of life (Physical Component Score β = -1.56 [-2.44 to -0.68]; p = 0.001; Mental Component Score β = -1.45 [-2.37 to -0.53]; p = 0.002) and more severe self-reported symptoms. In contrast, Acute Physiology and Chronic Health Evaluation II score and mechanical ventilation days were not associated with health-related quality of life. Older age (β = 0.33 [0.19-0.47]; p < 0.001) and lower social deprivation (β = 1.38 [0.03-2.74]; p = 0.045) were associated with better Mental Component Score health-related quality of life. Preexisting comorbidity counts, but not severity of ICU illness, are strongly associated with health-related quality of life and physical symptoms in the year following critical illness.

Relative Importance of Demographics, Locale, and Seasonality Underlying Louse and Flea Parasitism of Raccoons (Procyon lotor)

A variety of demographic, seasonal, and site-specific variables may influence parasitism, but the relative importance of these variables is generally unclear. We measured the relative ability of host characteristics, season, and site to explain louse (Trichodectes octomaculatus) and flea (Orchopeas howardi) infestation across 10 populations of raccoons (Procyon lotor). Lice are highly dependent on specific hosts and are predicted to display a relatively strong relationship with factors intrinsic to the host, when compared to fleas, which can infest multiple species and survive off-host for weeks without feeding. We developed a priori models that represented explicit hypotheses and contrasted their ability to predict infestation patterns. While the abundance of lice was seasonal, models that included solely host age and sex best predicted prevalence and abundance, in part because males were infested with 3 times the number of lice than were females. Conversely, flea prevalence and abundance, which peaks sharply in the spring, was best predicted by season; factors intrinsic to the host were relatively unimportant for predicting abundance. These, and other, recent findings emphasize the need to simultaneously assess the relative importance of multiple ecological variables between parasite species when attempting to describe general trends and constraints of host-parasite associations.

The role of beverage consumption, physical activity, sedentary behavior, and demographics on body mass index of adolescents

The percentage of US adolescents who are overweight or at-risk of overweight has increased over the past 20 years. Using data from the third National Health and Nutrition Examination Survey 1988–1994, multivariate regression models of body mass index (BMI) for adolescent males and females aged 12–16 years were developed to examine the relative importance of demographics, beverage consumption, physical activity, and sedentary behavior for maintaining a healthy body weight. The models explained between 11% and 19% of the variance in BMI. Demographic characteristics accounted for roughly one-half of the explained variance in the models. Age was positively associated with BMI for males and females. Family income had a negative association with BMI for females, but no association with BMI for males. The variables for race/ethnicity and region were only occasionally statistically significant. A strong negative association was found between BMI and participation in team sports or exercise programs for both males and females. The estimate of the relationship between television viewing and BMI was positive but not statistically significant. Consumption of regular carbonated soft drinks (RCSD) and fruit drinks/ades—two beverages widely hypothesized to be positively associated with BMI—were not statistically significant in any of the models. Consumption of diet carbonated soft drinks was very low and was positively associated with BMI for females but not for males. The potential impacts of increasing participation in teams or exercise programs, reducing television viewing, and reducing RCSD consumption on BMI were examined. Increasing participation in teams or exercise programs consistently had the largest impact on reducing predicted BMI. The impact of reducing television viewing had the next largest impact. Reducing consumption of RCSD had the smallest impact. Policies that revitalize physical activity and physical education programs for all students—not just student athletes—and educational efforts that discourage sedentary behavior will be far more successful in combating overweight than an undue focus on beverage consumption.