Metal matrix composites (MMCs), known for their low density and superior stiffness, have gained significant attention in various load bearing and fatigue-prone applications. These composites offer distinct advantages over traditional monolithic metals, including enhanced mechanical and tribological properties, making them prime candidates for lightweight structural applications. Among ceramic reinforcements, boron carbide stands out due to its lower density, high elastic modulus, excellent refractoriness, and superior hardness, positioning it as an ideal reinforcement material. This review delves into the processing techniques, material properties, and microstructural characteristics of boron carbide-reinforced MMCs, with a focus on aluminum LM6 alloy as the matrix. Additionally, the paper explores the latest advancements and emerging opportunities for employing these composites in fatigue-critical applications, highlighting their potential to revolutionize industries requiring high performance and durability under repeated loading conditions.