Abstract Significance Studying the flow of ternary nanofluids [Ag, Cu, MoS2] holds significant importance in both science and engineering. Ternary nanofluids are vital in advancing thermal management systems, heat exchangers, aerospace, and materials processing applications. Purpose This study investigates the ternary hybrid Carreau nanofluid numerically for thermal proficiency in the inclined magnetized environment. In this study, three distinct nanoparticles of [Ag, Cu, MoS2] and base fluid water over the wedge are used. The velocity of nanofluids is judged under the influence of an inclined magnetic field, and the thermal performance is scrutinized by incorporating the thermal radiation effect. Methodology The physical problem generates partial differential equations, which are transformed into ordinary differential equations (ODEs) through similarity variables. These ODEs are linearized into a system of ODEs and then passed under the bvp4c Matlab program to get the solution. This solution is again trained by an artificial neural network, and further results are obtained with both schemes and compared. Findings The most rapid heat transport analysis is found for ternary hybrid nanofluids compared to bi-hybrid nanofluids. The thermal radiation parameters and the magnetic environment augment the rate of heat transport.