Regularization Procedure Research Articles

Remarks on the origin of almost-Gaussian scaling in asymptotically safe quantum gravity

The gravitational asymptotic safety program envisions the high-energy completion of gravity through an interacting renormalization group fixed point, the Reuter fixed point. The predictive power of the construction is encoded in the spectrum of the stability matrix which is obtained from linearizing the renormalization group flow around this fixed point. A key result of the asymptotic safety program is that parts of this spectrum exhibit an almost-Gaussian scaling behavior, entailing that operators which are classically highly UV irrelevant do not induce new free parameters. In this article, we track down the origin of this property by contrasting the structure of the stability matrix computed from the Wetterich equation and the composite-operator equation within the realm of f(R) truncations. We show that the almost-Gaussian scaling is not linked to the classical part of the beta functions. It is a quantum-induced almost-Gaussian scaling originating from the quantum corrections in the flow equation. It relies on a subtle interplay among the analytic structure of the theory’s two-point function and the way the Wetterich equation integrates out fluctuation modes. As a byproduct we determine the parts of the eigenmode spectrum that is robust with respect to changing the regularization procedure. Published by the American Physical Society 2024

Regularized-renormalized-resummed loop corrected power spectrum of non-singular bounce with Primordial Black Hole formation

We present a complete and consistent exposition of the regularization, renormalization, and resummation procedures in the setup of having a contraction and then non-singular bounce followed by inflation with a sharp transition from slow-roll (SR) to ultra-slow roll (USR) phase for generating primordial black holes (PBHs). We consider following an effective field theory (EFT) approach and study the quantum loop corrections to the power spectrum from each phase. We demonstrate the complete removal of quadratic UV divergences after renormalization and softened logarithmic IR divergences after resummation and illustrate the scheme-independent nature of our renormalization approach. We further show that the addition of a contracting and bouncing phase allows us to successfully generate PBHs of solar-mass order, MPBH∼O(M⊙)\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$M_\ extrm{PBH}\\sim \\mathcal{O}(M_{\\odot })$$\\end{document}, by achieving the minimum e-folds during inflation to be ΔNTotal∼O(60)\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$\\Delta N_{\ extrm{Total}}\\sim \\mathcal{O}(60)$$\\end{document} and in this process successfully evading the strict no-go theorem. We notice that varying the effective sound speed between 0.88⩽cs⩽1\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$0.88\\leqslant c_{s}\\leqslant 1$$\\end{document}, allows the peak spectrum amplitude to lie within 10-3⩽A⩽10-2\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$10^{-3}\\leqslant A \\leqslant 10^{-2}$$\\end{document}, indicating that causality and unitarity remain protected in the theory. We analyse PBHs in the extremely small, MPBH∼O(10-33-10-27)M⊙\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$M_{\ extrm{PBH}}\\sim \\mathcal{O}(10^{-33}-10^{-27})M_{\\odot }$$\\end{document}, and the large, MPBH∼O(10-6-10-1)M⊙\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$M_{\ extrm{PBH}}\\sim \\mathcal{O}(10^{-6}-10^{-1})M_{\\odot }$$\\end{document}, mass limits and confront the PBH abundance results with the latest microlensing constraints. We also study the cosmological beta functions across all phases and find their interpretation consistent in the context of bouncing and inflationary scenarios while satisfying the pivot scale normalization requirement. Further, we estimate the spectral distortion effects and shed light on controlling PBH overproduction.

Kerr black hole mimickers sourced by a string fluid

We present rotating solutions of Einstein's gravity coupled to an effective Born-Infeld theory that describes the end of open-string tachyon condensation after the decay of an unstable D-brane or a brane-antibrane system. The geometry of these solutions is that of the rotating frozen star. The solutions are stationary, ultracompact, can be made non-singular via a regularization procedure and their exterior geometry is identical, for all practical purposes, to that of the Kerr solution. The Born-Infeld matter consists of radial electric-flux tubes that emanate from, or end at, the ellipsoidal core of the star. Each end of the flux tubes carries an electric charge, so that the electric field can be viewed as being sourced by an ellipsoidal charge distribution of positive and negative charges near the center of the star. Meanwhile, the star's outer layer is equal and oppositely charged, resulting in a vanishing electric field in the external spacetime. We show that these rotating solutions are ultrastable against radial perturbations, just like their static frozen star counterparts. They are also effectively immune to ergoregion instabilities, as we discuss.

Regularized Regression Can Reintroduce Backdoor Confounding: The Case of Mass Polarization

Regularization can improve statistical estimates made with highly correlated data. However, any regularization procedure embeds assumptions about the data generating process that can have counterintuitive consequences when those assumptions are untenable. We show that rather than simply shrinking estimates, regularization can reopen backdoor causal paths, inflating the estimates of some effects, and in the wrong circumstances, even reversing their direction. Recently, Cavari and Freedman (2023), argued that declining cooperation rates in surveys have inflated measures of mass polarization. We show that this finding is driven by large penalty terms in their regularized regressions, which leads to the estimates being confounded with time. Alternative methods do not show a clear positive or negative effect of declining cooperation on estimated levels of mass polarization.

Sommerfeld enhancement at NLO and the dark matter unitarity bound

We reexamine the consequences of perturbative unitarity on dark matter freeze-out when both Sommerfeld enhancement and bound state formation affect dark matter annihilations. At leading order the annihilation cross section is infrared dominated and the connection between the unitarity bound and the upper bound on the dark matter mass depends only on how the different partial waves are populated. We compute how this picture is modified at next-to-leading order with the goal of assigning a reliable theory uncertainty to the freeze-out predictions. We explicitly compute next-to-leading order corrections in a simple model with Abelian gauge interactions and provide an estimate of the theoretical uncertainty for the thermal masses of heavy electroweak n-plets. Along the way, we clarify the regularization and matching procedure necessary to deal with singular potentials in quantum mechanics with a calculable, relativistic UV completion. Published by the American Physical Society 2024

A Literature Review on the Uncommon Use of Extraoral Periapical Radiography

Periapical radiography is a regular radiographic procedure performed by dentists. However, at times, it may not be possible to position the image receptor into a patient’s mouth in an optimized or practical way. For these cases, some dentists advocated the use of extraoral periapical radiography (EOPA). This literature review aimed to review the dental literature on the use of EOPA. In October 2023, PubMed, Web of Science, and Scopus were searched to identify papers that reported on the use of EOPA, supplemented by manual reference tracing and Google Scholar searches. After screening, 18 papers published between 2003 and 2022 were identified, including 14 original articles and 4 reviews. From very limited and conflicting evidence, it was found that root length/working length measurements between EOPA and IOPA did not significantly differ or EOPA showed inferiority. No data were available to compare EOPA with other extraoral modalities such as panoramic radiography. The technique used in EOPA to visualize posterior teeth in the maxilla and mandible varied across studies, such as the vertical angulation of the primary beam, whether mouth should be opened or closed, and whether a holder should be used or not. At the current time, EOPA probably should not be advocated for regular use.

Efficient fuzzy simulations for estimating the failure credibility of engineering structures under fuzzy environment

Efficiently and accurately solving the failure credibility of a structural system plays a significant role in the engineering field under fuzzy environment. A more precise failure credibility can help assess the safety degree of the system, and then reduce the occurrence of security accidents. At present, the extended fuzzy first-order and second-moment method (EFFOSM) is effective to analyze failure credibility for some occasions. However, when it comes to complicated performance functions and fuzzy inputs, the accuracy of EFFOSM is greatly reduced and its efficiency also needs to be improved. To overcome the above shortcomings, this paper proposes two types of novel fuzzy simulation algorithms, namely uniform discretization algorithm (UDA) and bisection simulation algorithm (BSA). For the system involving frequently-encountered continuous and strictly monotone performance functions of regular LR fuzzy interval inputs, these two algorithms are designed to estimate failure credibility with higher efficiency and accuracy. Subsequently, with the aid of the linearization and regularization procedures in EFFOSM, the application of UDA and BSA is extended to non-monotone performance functions of irregular LR fuzzy intervals. To evaluate and verify the performance of the proposed two algorithms, their comparisons with EFFOSM are conducted through some numerical examples and practical problems. The results show that the proposed two algorithms outperform EFFOSM in terms of accuracy and efficiency, and also have wider application range for estimating the failure credibility of strictly monotone performance functions involving regular LR fuzzy interval inputs. Meanwhile, BSA is slightly better than UDA for the less runtime.

Building paper bridges: adapting citizenship and immigration regimes to international displacement

Implementation gaps in the areas of naturalization and immigrant regularization emerge through a mismatch between the documents a residence country requires, and the documents that refugees and migrants can realistically provide. Those caught in this gap may live undocumented or risk statelessness. Residence countries can close such paperwork gaps by adapting legal interpretations and easing administrative requirements. When Colombia faced large-scale international displacement from Venezuela, state actors identified documentation-based implementation gaps in its nationality law and regularization procedures; they then took an innovative – yet not faultless – approach by adapting its citizenship and immigration regimes to accommodate displaced Venezuelans. These changes strengthened access to essential rights and increased the well-being of many. In this article, we develop the concepts of paperwork gaps and paper bridges and discuss the actors, impact, and limitations of Colombia’s policy innovations in the areas of nationality by birth, naturalization, and regularization based on research conducted from 2020 to 2023. The study advances the literature on government learning regarding policies within citizenship and immigration regimes that target internationally displaced populations.

An efficient numerical model for the sound radiation from a supported rail

In this work, the sound radiation of a supported rail is investigated using a numerical 2.5D Finite Element model that is coupled with a 2.5D Boundary Element model. The vibration of the track is modelled by coupling the infinite rail to an equivalent continuous double-layer support and is used as input for calculating the consequent sound radiation. An interpolation method that allows for a quick solution of the boundary element calculations is proposed and validated by comparison with an analytical solution, showing differences less than 0.1 dB. The assembled model is used for calculating the sound radiation from the rail in terms of sound power per unit squared force applied to the rail head in vertical and lateral directions for three different rail configurations. The transfer functions obtained can be used in rolling noise calculations. The proposed interpolation method allows calculations that are more than 100 times faster than the regular procedure for the case considered.

Regularisation and iterated regularisation of Hamiltonian systems of the second quasi-Painlevé equation

In this paper we consider several Hamiltonian functions for the second quasi-Painlevé equation. One of the features of these functions is that they give rise to the same final chart regular systems once using certain blowups and twists in the regularisation procedure. We also discuss what happens if we iterate the blowup process for these final chart systems. Using birational transformations between different Hamiltonian systems we show how to construct new Hamiltonian functions which give rise to the second quasi-Painlevé equation with shifted coefficients. We also give an explicit example of the Bäcklund transformation.

LIMBERG FLAP FOR SACROCOCCYGEAL PILONIDAL SINUS: A SAFE AND PROMISING SURGERY

Introduction:Sacrococcygeal pilonidal sinus is a common disease of the adult age group, especially male population, causing significant morbidity from both disease and surgery done for the same. It is essentially a cleavage between the buttocks (i.e., natal cleft), and diagnosis is made by identifying the epithelialized follicle opening (i.e., sinus). The name PILONIDAL is taken from Latin meaning nest of hairs. The estimated incidence is 26 per 1,00,000 people1. It generally presents as a cyst, abscess, or sinus tract with or without discharge2. Men affected more often than women1, rare both before puberty and after the age of 40 years3. The etiology of the pilonidal sinus is a matter of controversy. Aims & Objectives:Literature study showed that Limberg flap reconstruction following rhomboid excision of the sinus area was superior to primary closure and other flap procedures and a safe and reliable method in sacrococcygeal pilonidal sinus disease with low complication and recurrence rates. Hence, this study was performed in our setup to evaluate the usefulness of Limberg flap procedure in sacrococcygeal pilonidal sinus, patient compliance, complications and long-term recurrence rates following the procedure. Materials & Methods:The study involves 22 patients, from May 2022 to September 2023. Most of the patients were males of those 4 were females. Average age was 24 years—the oldest was 29 years and the youngest was 15 years. Results:In this study 22 patients were included. Among them 18 were males and 4 were females. Mean age was 24 years (range 15–29 years). Of the 22 patients, 14 had primary disease, 6 had recurrent disease, and 2 came up after having previous incision and drainage for abscess. All patients came with pilonidal sinus, from May 2022, were assessed for its severity and investigated, and then they underwent Limberg flap surgery under spinal anesthesia. Discussion:Sacrococcygeal pilonidal sinus is blind epithelial tract situated in the skin of the natal cleft, close to anal verge, generally containing hair. The etiology is matter of debate initially congenital origin was thought of which is now given up. Main causes for the formation of this sinus are hirsutism, sweating in the area, repeated maceration due to trauma, leading to breakage of the skin barrier, attracting hair inside which initiates a foreign body reaction leading to infection with abscess or sinus formation. Conclusion:Sacrococcygeal pilonidal sinus is headache to both the patient and the treating surgeon because of its repeated infection, persistent pain with discharge, and high recurrence rates with regular procedures.

Modified homotopy approach for diffractive production in the saturation region

In this paper we continue to develop the homotopy method for solving of the nonlinear evolution equation for the diffractive production in deep inelastic scattering. We introduce part of the nonlinear corrections as a first step of this approach. This simplified nonlinear evolution equation is solved analytically taking into account the initial and boundary conditions for the process. At the second step of our approach we demonstrated that the perturbative procedure can be used for the remaining parts of the nonlinear corrections. It turns out that these corrections are small and can be estimated in the regular iterative procedure. Published by the American Physical Society 2024

Trends in body mass index for people with and without HIV: Pooled analysis of nationally-representative health surveys from 10 countries and 173,800 adults in Africa.

It remains unclear if and how body mass index (BMI) levels have changed over time in HIV endemic regions. We described trends in mean BMI and prevalence of overweight between 2003-2019 in 10 countries in Africa including people living with (PLWH) and without (PLWoH) HIV. We pooled Demographic and Health Surveys (DHS) from countries where ≥2 surveys >4 years apart were available with height/weight measurements and HIV tests. HIV status was ascertained with a finger-prick dried blood spot (DBS) specimen tested in a laboratory. The DBS is taken as part of the regular DHS procedures. We summarized age and socioeconomic status standardized sex-specific mean BMI (kg/m2) and prevalence of overweight (BMI ≥25 kg/m2) by HIV status. We fitted country-level meta-regressions to ascertain if changes in ART coverage were correlated with changes in BMI. Before 2011, women LWH (22.9 [95% CI: 22.2-23.6]) and LWoH (22.6 [95% CI: 22.3-22.8]) had similar mean BMI. Over time, mean BMI increased more in women LWH (+0.8 [95% CI: 0.7-0.8] BMI units) than LWoH (+0.2 [95% CI: 0.2-0.3]). Before 2013, the mean BMI was similar between men LWH (21.1 (95% CI: 20.3-21.9)) and LWoH (20.8 (95% CI: 20.6-21.1)). Over time, mean BMI increased more in men LWoH (+0.3 [95% CI: 0.3-0.3]) than LWH (+0.1 [95% CI: 0.1-0.1]). The same profile was observed for prevalence of overweight. ART coverage was not strongly associated with BMI changes. Mean BMI and prevalence of overweight were similar in PLWH and PLWoH, yet in some cases the estimates for PWLH were on track to catch up with those for PLWoH. BMI monitoring programs are warranted in PLWH to address the rising BMI trends.

The Spread of Mycobacterium chimaera from Heater-Cooler Units and Infection Risk in Heart Surgery: Lessons from the Global Outbreak?

Mycobacterium chimaera (MC), a member of the Mycobacterium avium complex, can cause infections in patients after open-heart surgery due to contaminated heater-cooler units (HCUs). The transmission route of HCU-related MC infection is non-inhalational, and infection can occur in patients without previously known immune deficiency. Patients may develop endocarditis of the prosthetic valve, infection of the vascular graft, and/or manifestations of disseminated mycobacterial infection (splenomegaly, arthritis, hepatitis, nephritis, myocarditis, etc.). MC infections have serious outcomes (30-50% recurrence rate, 20-67% mortality rate). In 2015, an international outbreak of M. chimaera infections among patients undergoing cardiothoracic surgeries was associated with exposure to contaminated LivaNova 3T HCUs (formerly Stöckert 3T heater-cooler system, London, United Kingdom). In response to the global outbreak, many international agencies have issued directives and recommendations in order to reduce the risk of MC infection in cardiac surgery. Whole-genome sequencing (WGS) technology can be used to describe the global spread and dynamics of MC infections, to characterize local outbreaks, and also to identify sources of infection in hospital settings. In order to minimize the risk of contamination of HCUs and reduce the risk of patient infection, it is imperative that healthcare facilities establish a program of regular cleaning and disinfection maintenance procedures as well as monitoring of the water used and the air in the operating room, in accordance with the manufacturer's procedure.

The Effect of a Separate Flow of Patients With Small Traumatic Injuries on Consult Time and Patient Satisfaction: A Retrospective Cohort Study During COVID-19 in the Emergency Department.

With emergency department (ED) crowding and high workloads burdening healthcare, efficient patient flow management becomes increasingly crucial. A significant portion of this crowding is attributed to patients with minor traumatic injuries. The objective of this study is to investigate to what extent a separate patient flow for patients with small traumatic injuries influences consult times and patient satisfaction. During COVID-19, patients with small traumatic injuries in the ED were redirected to an outpatient clinic (the Fracture Clinic). The Fracture Clinic was maintained for seven weeks during which the consult time and patient satisfaction were recorded for every individual. Retrospectively, the same procedure was followed for the seven weeks prior to the outbreak of COVID, with the regular procedure in place. In total, 922 patients were included in the research: 415 patients in the intervention group (Fracture Clinic) and 507 patients in the control group (ED group). The consult time in the Fracture Clinic (median = 30 min) is significantly lower compared to the ED group (median = 86 min) (U = 25,147.500, z = 19.9, p < 0.001). The overall consult in terms of patient satisfaction scored higher for the Fracture Clinic Group than the ED group (T[df] = -4.449 [479], p < 0.001). The Fracture Clinic resulted in shorter consult times and an increased patient satisfaction compared to the usual patient flow for patients with small traumatic injuries in the ED. These patients could be redirected to an outpatient clinical setting to improve efficiency in patient flow, while avoiding a negative impact from the triage system in which they usually are the lowest priority.

Dependence of dense filament frontogenesis in a hydrostatic model

In this study, a hydrostatic model - the Navy Coastal Ocean Model (NCOM) is used to analyze the temporal evolution of a cold filament under moderate wind (along / cross filament) and surface cooling forcing conditions. The experimental framework adhered to the setup used in large eddy simulations by Sulllivan and McWilliams (2018). For each forcing scenario, the impact of horizontal resolutions is systematically explored through varies model resolutions of 100 m, 50 m, and 20 m; and the influence of horizontal mixing is investigated by adjusting the Smagorinsky constant within the Smagorinsky horizontal mixing scheme. The role of surface gravity waves is also assessed by conducting experiments both with and without surface wave forcing.The outcomes of our study revealed that while the hydrostatic model is able to predict the correct characteristics/physical appearance of filament frontogenesis, it fails to capture the precise dynamics of the phenomenon. Horizontal mixing parameterization in the model was found to have marginal effect on frontogenesis, and the frontal arrest is controlled by the model's subgrid-scale artificial regularization procedure instead of horizontal shear instability. Consequently, higher resolution is corresponding to stronger frontogenesis in the model. Thus, whether the hydrostatic model can produce realistic magnitude of frontogenesis is purely dependent on the characteristic of the front/filament simulated and model resolution. Moreover, examination of the parameterized effect of surface gravity wave forcing through vertical mixing unveiled a limited impact on frontogenesis, suggesting that the parameterization falls short in representing the real physics of wave-front interaction.

An optimal Bayesian strategy for comparing Wiener–Hunt deconvolution models in the absence of ground truth

Abstract This paper considers the quantitative comparison of several alternative models to perform deconvolution in situations where there is no ground truth data available. With applications to very large data sets in mind, we focus on linear deconvolution models based on a Wiener filter. Although comparatively simple, such models are widely prevalent in large scale setting such as high-resolution image restoration because they provide an excellent trade-off between accuracy and computational effort. However, in order to deliver accurate solutions, the models need to be properly calibrated in order to capture the covariance structure of the unknown quantity of interest and of the measurement error. This calibration often requires onerous controlled experiments and extensive expert supervision, as well as regular recalibration procedures. This paper adopts an unsupervised Bayesian statistical approach to model assessment that allows comparing alternative models by using only the observed data, without the need for ground truth data or controlled experiments. Accordingly, the models are quantitatively compared based on their posterior probabilities given the data, which are derived from the marginal likelihoods or evidences of the models. The computation of these evidences is highly non-trivial and this paper consider three different strategies to address this difficulty—a Chib approach, Laplace approximations, and a truncated harmonic expectation—all of which efficiently implemented by using a Gibbs sampling algorithm specialised for this class of models. In addition to enabling unsupervised model selection, the output of the Gibbs sampler can also be used to automatically estimate unknown model parameters such as the variance of the measurement error and the power of the unknown quantity of interest. The proposed strategies are demonstrated on a range of image deconvolution problems, where they are used to compare different modelling choices for the instrument’s point spread function and covariance matrices for the unknown image and for the measurement error.

Distribution of Relaxation Times Analysis of PEMFC through Loewner Framework: A Direct and Regularization Free Approach

The analysis and interpretation of electrochemical impedance spectroscopy (EIS) data are often complex and challenging, despite its popularity within the field of electrochemistry. Hence, recently, we have introduced novel data-driven approach for extracting the distribution of relaxation times (DRT) from impedance data in order to improve further analysis [1, 2]. This approach is based on the Loewner framework, which is a versatile and straightforward data-driven modeling method that computes reduced-order models in a state-space representation directly from frequency response data. Thus, it allows estimation of DRT without need of regularization procedures or iterative optimization algorithms.The effectiveness of this approach is successfully demonstrated by analysing the experimental EIS data of a polymer electrolyte membrane fuel cell (PEMFC). The results show that this method allows clear identification of the individual polarization processes based on their characteristic time constants (see Figure). Furthermore, the peaks observed in the DRT plot are correctly associated with different processes by examining spectra under various operating conditions. This is further validated by employing a physics-based model [3]. In this way, unambiguous fault identification and monitoring of the degradation state of the cell is possible and it can be the foundation for an on-board diagnostic tool.

Strategic use of 4 % deltamethrin impregnated-collar in seropositive dogs reduces the incidence of seroreactivity to visceral leishmaniasis in dogs from endemic areas

The effectiveness of a visceral leishmaniasis (VL) control strategy based on the application of 4 % deltamethrin impregnated collars (DIC) exclusively in seropositive dogs was assessed between 2018 and 2019, through a prospective study. The effectiveness of DIC-collaring was evaluated by comparing the incidence rate of anti-leishmanial antibodies among dogs from two endemic districts in Brazil. In one of the areas, the conventional control measure which is based on the non-compulsory euthanasia of LV seropositive dogs, was practiced by the official healthy service as a regular procedure, whereas strategic collaring, conceived in this study, was carried out in the other. Results of serological tests applied to serum samples collected from all domiciled dogs were evaluated in three consecutive times, spaced by around 200 days. Incidence rates of VL seroreactivity were compared between districts in the same period of time as well as within the same district, in consecutive periods. Based on the results, the risk of infection in the population under conventional control measure was up to four times higher than the risk of infection where DIC-collaring was used. The strategic use of collar proposed here emerged as a promising measure for VL control in dogs from endemic areas. Strategic collaring does not rely on the euthanasia of infected animals, an extremely controversial procedure, and instead of being used in all dogs, as collaring is normally recommended; only seropositive dogs are intervened. Strategic use of DIC has the potential to drastically reduce costs, if compared to mass collaring canine population.

Strategic design for Research and Innovation through a participatory approach: lessons learnt in a Veterinary Public Health Institution.

The article describes the results and the experience gained in using a participatory approach to design a strategic development plan (SDP) in a veterinary public health institute. The bottom-up approach utilised was co-designed between the units of "Research and Innovation" and "Training". It included a survey administered to the institute staff (570 people) to collect inputs on three relevant areas: i) innovative research topics; ii) innovation needed to improve services; iii) new tools to carry out activities. After the survey, the following criteria were used to prioritise the research topics: appropriateness, relevance, capacity, impact and innovativeness. Based on the priority topics identified, small working groups were set up on a voluntary basis. The working groups, following the EuropeAid method, co-designed a SDP, set over a three-year period, with indications on aims, objectives, outputs, activities, SMART indicators, means of verification and targets. The method proved useful in continuing the process of institutional innovation, especially by stimulating the participation and commitment of younger innovative staff at the bottom of the hierarchical pyramid. The integration of the described method into regular management procedures would be desirable, to achieve more effective results.