Regular Aerobic Exercise Research Articles

Cardiopulmonary Fitness and Personalized Exercise Prescription in Patients With Hypertrophic Cardiomyopathy.

Patients with hypertrophic cardiomyopathy (HCM) are generally restricted regarding participation in competitive sports based on the potential risk of sudden cardiac death and malignant arrhythmias. As a result, they are often inactive and experience the negative consequences of a sedentary lifestyle. Hence, the need arises to strike the right balance between these 2 extremes through personalized exercise prescription. The aims of this study were (1) to assess the characteristics of patients with HCM practicing regular aerobic physical activity compared with sedentary patients; (2) to perform a personalized moderate-intensity exercise prescription and evaluate its effects. Patients with HCM were evaluated through clinical assessment, ECG, ambulatory ECG monitoring, echocardiography, and cardiopulmonary testing. A personalized moderate-intensity exercise prescription was performed, and the same investigations were repeated. Physically active patients with HCM demonstrated better cardiopulmonary functional capacity than sedentary patients (oxygen consumptionpeak/kg 32.9±7.4 versus 25.2±7.4 mL/min per kg P≤0.0001, ventilation/carbon dioxide production slope 26.7±4.3 versus 29.9±5.2 P=0.004), with similar prevalence of ventricular arrhythmias (P=0.43). Sedentary subjects showed a borderline higher prevalence of obesity (P=0.07) than physically active subjects. Moderate-intensity exercise prescription led to improved cardiopulmonary fitness without occurrence of adverse events. Patients with HCM practicing regular aerobic exercise have a better functional capacity in the absence of relevant events than sedentary patients. Conversely, a sedentary lifestyle led to a deterioration of cardiopulmonary functional capacity and fitness. The tailored moderate-intensity personalized exercise prescription appears to be a feasible approach in carefully selected patients with HCM to counterbalance the negative effects of sedentary behavior without significant major events.

Aerobic exercise effects on systolic blood pressure and endothelial inflammation in obese and non-obese elderly women with isolated systolic hypertension.

This study aimed to investigate the effects of a 16-week aerobic exercise program on systolic blood pressure, intracellular cell adhesion molecule-1, vascular cell adhesion molecule-1, and oxidized low-density lipoprotein of obese and nonobese elderly women with isolated systolic hypertension. Elderly women aged 70-85 years were recruited and grouped into the normal isolated systolic hypertension ( n = 12) and obese isolated systolic hypertension groups ( n = 13). The participants followed an aerobic exercise program, using a wireless heart rate monitor to maintain an appropriate heart rate reserve based on the American College of Sports Medicine exercise guidelines. The two-way repeated measures analysis of variance tested group × time interaction. Pearson's correlation and simple regression assessed the influence of each variable, which showed significant differences. An interaction effect for systolic blood pressure, intracellular cell adhesion molecule-1, and vascular cell adhesion molecule-1 ( P < 0.05) and a main time effect for oxidized low-density lipoprotein ( P < 0.05) were observed. A correlation between the rates of change in systolic blood pressure and vascular cell adhesion molecule-1 ( P < 0.05) with a 42.8% influence ( P < 0.001) and in intracellular cell adhesion molecule-1 and vascular cell adhesion molecule-1 ( P < 0.05) with a 21.6% influence ( P < 0.05) was observed. These findings collectively showed that the 16-week aerobic exercise program effectively lowered blood pressure in patients with isolated systolic hypertension, particularly in the normal group compared to the obese group. Thus, regular aerobic exercise for 16 weeks or more enhances vascular health, potentially improving the healthy life expectancy of elderly women.

8-weeks aerobic exercise ameliorates cognitive deficit and mitigates ferroptosis triggered by iron overload in the prefrontal cortex of APP Swe/PSEN 1dE9 mice through Xc-/GPx4 pathway.

Alzheimer's disease (AD) is a degenerative disorder of the central nervous system characterized by notable pathological features such as neurofibrillary tangles and amyloid beta deposition. Additionally, the significant iron accumulation in the brain is another important pathological hallmark of AD. Exercise can play a positive role in ameliorating AD, but the mechanism is unclear. The purpose of the study is to explore the effect of regular aerobic exercise iron homeostasis and lipid antioxidant pathway regarding ferroptosis in the prefrontal cortex (PFC) of APP Swe/PSEN 1dE9 (APP/PS1) mice. Eighty 6-month-old C57BL/6 J and APP/PS1 mice were divided equally into 8-weeks aerobic exercise groups and sedentary groups. Subsequently, Y-maze, Morris water maze test, iron ion detection by probe, Western Blot, ELISA, RT-qPCR, HE, Nissle, Prussian Blue, IHC, IF, and FJ-C staining experiments were conducted to quantitatively assess the behavioral performance, iron levels, iron-metabolism-related proteins, lipid antioxidant-related proteins and morphology in each group of mice. In APP/PS1 mice, the increase in heme input proteins and heme oxygenase lead to the elevated levels of free iron in the PFC. The decrease in ferritin content by ferritin autophagy fails to meet the storage needs for excess free iron within the nerve cells. Ultimately, the increase of free ferrous iron triggers the Fenton reaction, may lead to ferroptosis and resulting in cognitive impairment in APP/PS1 mice. However, 8-weeks aerobic exercise induce upregulation of the Xc-/GPx4 pathway, which can reverse the lipid peroxidation process, thereby inhibiting ferroptosis in APP/PS1 mice. 8 weeks aerobic exercise can improve learning and memory abilities in AD, upregulate GPx4/Xc- pathway in PFC to reduce ferroptosis induced by AD.

Aerobic Exercise Training for the Aging Brain: Effective Dosing and Vascular Mechanism.

This article presents evidence supporting the hypothesis that starting aerobic exercise in early adulthood and continuing it throughout life leads to significant neurocognitive benefits compared with starting exercise later in life. Regular aerobic exercise at moderate-to-vigorous intensity during midlife is associated with significant improvement in cardiorespiratory fitness, which may create a favorable brain microenvironment promoting neuroplasticity through enhanced vascular function.

Mitigating the Adverse Effects of Night Shifts: A Review of Strategies for Enhancing Health Outcomes in Shift Workers

Introduction and PurposeShift work, essential for continuous operation in industries like healthcare, transportation, and security, disrupts circadian rhythms and adversely affects health. This review consolidates findings on the multifaceted impacts of night shift work, emphasizing interventions to mitigate these effects and improve worker health and well-being. Brief Description of the State of KnowledgeNight shift work disrupts circadian rhythms, leading to cognitive decline, sleep disorders, mental health risks, cardiovascular issues, metabolic disturbances, and cancer susceptibility. Effective interventions include limiting shift lengths and frequency, incorporating rest breaks and napping, aligning meal times with circadian rhythms, using melatonin supplementation and light therapy to improve sleep quality, engaging in regular aerobic exercise, and employing stress management techniques. Summary Implementing proposed interventions can mitigate the adverse health effects of night shift work, enhancing worker well-being, efficiency, and job satisfaction. Tailoring strategies to different age groups optimizes effectiveness, with structured approaches beneficial for older workers and flexible options suitable for younger workers. Further research should explore long-term intervention effects and develop personalized strategies for diverse populations. This review provides comprehensive guidelines for managing the health impacts of night shift work, supporting improved patient safety, reduced accidents, and enhanced work performance across various industries.

The Effect of Aerobic Exercise Frequency on Reducing Blood Glucose in Type 2 Diabetes Mellitus Sufferers in the Lingsar Health Center Working Area in 2024

One of the keys to a person suffering from diabetes mellitus being able to live a healthy life like other people without diabetes is to maintain balanced blood glucose levels within normal limits. One important way to reduce blood glucose levels, especially in type 2 DM sufferers, is exercise. This study aims to identify the effect of aerobic exercise, on changes in blood glucose levels. This research is a pre-experimental research with a one group pre-posttest approach. The research sample was 33 people suffering from type 2 DM at the Lingsar Community Health Center, selected using a simple random sampling technique. Each respondent was given aerobic exercise 3 times a week with a minimum duration of 20 minutes. Data on blood glucose levels before and after the intervention were collected using an observation sheet. The results of the study showed that the average blood glucose before the intervention was 162.2 mg/dL and after the intervention it fell to 156.14 mg/dL. The t-test with a=0.05 showed r=0.000. It can be concluded that there is an effect of aerobic exercise on the respondents' blood glucose levels. Aerobic exercise has been proven to reduce the average blood glucose level after this is done regularly. This study results can be an evidenced base for community nursing to promote regular aerobic exercise among people with DM, to help reduce or control their blood glucose.

The Impact of Aerobics on Chinese Women's Psychological Health and Well-Being

The researcher aimed to assess the impact of aerobics participation on the psychological health and well-being of Chinese female students, focusing on their mental health, quality of life, self-esteem, body image, mood states, sense of belonging, and coping strategies. The study examined the respondents' profiles, including age, length of engagement, and course, to determine if these factors influenced their assessments. Additionally, it explored challenges in maintaining a regular aerobic exercise routine, the long-term psychological benefits anticipated from continued participation, and proposed a Wellness Initiative Program based on the findings. The study utilized the Descriptive research design employing both quantitative and qualitative methods of research and utilized 332 Chinese college students who are enrolled in Hengyang Normal University in Hengyang City, Hunan Province, must be enrolled this SY 2023-2024, and must be a female student who participated or enrolled in aerobics. The study revealed that young adults, mainly from the Chinese Language and Literature department, benefited from aerobics in terms of mental health and self-esteem, with older participants and those engaged longer seeing greater effects. The study recommends a Wellness Initiative Program through aerobics to improve women’s psychological health and well-being.

Anti-Inflammatory Effects of Regular Aerobic Exercise on Common Chronic Diseases and Their Mechanisms

Anti-Inflammatory Effects of Regular Aerobic Exercise on Common Chronic Diseases and Their Mechanisms

Enhancing brain health: Swimming-induced BDNF release and epigenetic influence in MS female mouse models

Multiple sclerosis (MS) is a condition characterized by inflammation in the central nervous system (CNS), impacting sensory, motor, and cognitive abilities. Globally, around three million individuals are affected by MS, with up to 97,000 cases in Iran attributed to genetic predispositions along with various environmental factors like smoking. Cognitive impairment affects a significant portion of patients, ranging from 45% to 70%. This study investigates the impact of regular aerobic swimming exercise for four weeks, mild cognitive impairment induced by encephalomyelitis, and their combination on the expression of microRNA-142-3p and its correlation with the release of brain-derived neurotrophic factor (BDNF) in relation to spatial memory. Twenty-one C57BL/6 mice were divided into three groups. RT-PCR was used for microRNA expression analysis, and BDNF levels were assessed via western blotting. Clinical scores and animal weights were monitored daily. EAE induction led to an increase in microRNA-142-3p expression and a decrease in BDNF levels compared to the control group. Exercise inversed them significantly, and improved spatial memory. Our findings indicate that engaging in regular swimming exercise can counteract the up-regulation of miR-142-3p in brain tissue, which likely contributes to mild cognitive impairment induced by MS. Additionally, the increase in BDNF following exercise appears to be associated with miR-142-3p and the enhancement of cognitive function. Thus, the therapeutic benefits of exercise, particularly in releasing BDNF to improve cognitive function in MS patients, warrant consideration. Lifestyle modifications have the potential to effectively modulate environmental influences and ethnicity, underscoring their significance in MS management.

Relationship of atherogenic index of plasma with exercise, obesity and biochemical parameters

Aims: It is well-known that regular moderate-intensity aerobic exercise has positive effects on various health indicators, including obesity and cardiovascular diseases (CVD) and atherogenic index of plasma (AIP) is defined as a highly sensitive predictor of plasma atherogenicity and cardiovascular risk. Furthermore, it is known that physical activity has a reducing effect on AIP with its ability to decrease visceral fat and its positive impact on blood lipids. Additionally, large-scale AIP screenings are recommended for the early detection of obese individuals and effective intervention. This study aims to determine the relationship between regular exercise and cardiometabolic parameters and obesity based on current data. Methods: The study involved a total of 126 participants aged 18-65 and it was conducted in the form of file screening, where the medical history reports of all patients were examined, and systemic physical findings were assessed. Fasting blood samples were used to determine the lipid profile. Anthropometric measurements and biochemical parameters of the participants were determined and AIP was calculated using the formula AIP=log10 (TG/HDL-C). Participants were categorized into groups based on their exercise status, BMI, and AIP risks, and the data of the study groups were evaluated statistically. Results: Participants were divided into two groups based on exercise status, and in the exercise group, body mass index (BMI), body weight, waist circumference, AIP, and triglyceride levels were found to be lower, while high-density lipoprotein (HDL) levels were higher compared to the non-exercise group. In all participants, moderate-intensity exercise was negatively correlated with AIP, body weight, BMI, waist circumference, triglyceride, and low-density lipoprotein (LDL) levels; and positively correlated with HDL levels. Conclusion: The relationships uncovered in this study among exercise, cardiometabolic parameters, and obesity status are expected to contribute to future research, especially in studies focusing on the impact of exercise on CVD and obesity.

Mediterranean Diet Combined with Regular Aerobic Exercise and Hemp Protein Supplementation Modulates Plasma Circulating Amino Acids and Improves the Health Status of Overweight Individuals.

Plant protein is considered a sustainable health-promoting strategy to prevent metabolic syndrome. Lifestyle changes (including dietary patterns and exercise) have been demonstrated to exert an effect on human health by modulating the biochemical status in humans. The objective of this study was to assess whether supplementation with hemp protein within a Mediterranean diet context together with exercise could help to ameliorate the metabolic statuses of patients prone to developing metabolic syndrome. For this study, 23 patients followed with Mediterranean diet and engaged in aerobic exercise according to the WHO's recommendations, while also being supplemented with hemp protein, for 12 weeks. A comparison of anthropometric, biochemical, and mineral data as well as amino acid values was made between the start and the end of the study, with the subjects acting as their own control group. Statistical analyses included a paired t-test, Wilcoxon paired test, Pearson correlation coefficient, and Sparse Partial Least Squares Discriminant Analysis to evaluate significant differences and correlations among parameters. There were statistically significant changes in total cholesterol, HDL-C (+52.3%), LDL-C (-54.0%), and TAG levels (-49.8%), but not in glucose plasma levels. Following the intervention, plasma concentrations of some amino acids, including α-aminoadipic acid, phosphoethanolamine, and 1-metylhistidine, increased, whereas those of asparagine and alanine declined. Different correlations between amino acids and the other parameters evaluated were reported and discussed. A Mediterranean diet combined with regular aerobic exercise, together with protein supplementation, can highly improve the metabolic parameters and anthropometric parameters of subjects with obesity and impaired glucose levels, ameliorating their health status and likely delaying the development of metabolic syndrome.

Effects of step aerobic exercises on rhythm skill and static balance

This study aimed to examine the effects of 8-week step aerobic exercises on the rhythm skills and static balance of young individuals. 53 university students participated in the research voluntarily. Participants practiced step aerobic exercises with a licensed trainer for 8 weeks. The participants' static balance and rhythm skills were observed before and after the study. At the end of the study, participants' BMI, static balance performance and rhythm skill performances changed significantly. Additionally, it was determined that there was a significant negative way relationship between the participants' balance performances and rhythm skills. Based on the research findings, it can be said that regular step aerobic exercises can be used as an effective method in developing the static balance and rhythm skills of young individuals.

Stopgap Measures for Obesity Prior to Surgery.

The data on preventive measures for managing obesity prior to surgery is limited. This review highlights the role of stopgap measures for managing obesity before surgery. Body weight regulation to achieve sustainable weight loss is a gradual process. Regular aerobic exercises, transformative yoga and restrained eating can contribute to a calorie deficit. Behavioural strategies aim to raise awareness, set goals, manage stress, and support adherence to healthier lifestyles. Pharmacotherapy can be adjunctive in inducing weight loss but could be better at maintaining weight. Intragastric balloon and endoscopic sleeve gastroplasty are restrictive procedures for patients before surgery. Obesity is a multifaceted chronic disease with adverse health consequences. There is a need to identify contributors to weight gain and treatment should target the cause of obesity. Utilize stop-gap measures and monitor progress for step-up or more intensive treatment. Structured weight loss needs lifelong commitment.

Effect of Regular Aerobic Exercise on Cognitive Function, Depression Level and Regulative Role of Neurotrophic Factor: A Prospective Cohort Study in the Young and the Middle-Aged Sample.

Mild cognitive impairment (MCI) and depressive disorder (DD), which are associated with unhealthy lifestyles, are prevalent worldwide. This study aimed to investigate the effects of regular aerobic exercise on cognitive function, depression, and the regulatory role of neurotrophic growth factors for providing scientific basis in preventing MCI and DD in healthy individuals. Eighty members of the fitness center and 80 community residents were recruited, who were administered by the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) and the Patient Health Questionnaire (PHQ-9). Brain-derived neurotrophic factor (BDNF) and glial cell-line-derived neurotrophic factor (GDNF) in the peripheral blood were detected by enzyme-linked immunosorbent assay (ELISA). The RBANS and other factor scores, except for visuospatial abilities, were higher and PHQ-9 scores were lower in the study group than in the control group. The concentrations of BDNF and GDNF in the study group were higher than those in the control group. RBANS and its factor scores positively and PHQ-9 negatively correlated with BDNF and GDNF levels. Finally, multiple regression analysis showed that BDNF, as a predictor of RBANS, could explain 59.90% of its variance and that GDNF was a predictor of PHQ-9 could explain 12.30% of the variance. Regular aerobic exercise can improve cognitive function and depressive symptoms by increasing the BDNF and GDNF levels.

Fresh goat's milk and Long-term aerobic exercise improve bone health in Athletes

Objective: To analyze the effect of fresh goat's milk intake and long-term aerobic exercise on serum calcium and its relationship to bone resorption in male athletes. Methods: This research was an experimental study using a pretest-posttest design with a control group design. Subjects were 29 gymnastics athlete volunteers: trial group (n=19) and control group (n=10), male, aged 19-26 years. The treatments were fresh goat milk (1x250ml/day, given from 07.00 p.m to 08.00 p.m) and aerobic exercise (3-5 times/week, medium intensity, duration 50-60 minutes), for 90 days. Results: The results showed that serum calcium levels in the trial group were significantly higher than in the control group (9.58±0.26; 9.87±0.32 vs. 9.74±0.42; 9.37±0.38: p=0.001) after consumption of goat milk and long-term regular physical exercise. The results also showed that there was a significant decrease in CTx-1 levels in the trial group compared with the control group (0.603±0.25; 0.45±0.16 vs. 0.73±0.32; 0.76±0.30: p=0.001) after goat milk intake and regular aerobic exercise. Conclusion: Consumption of fresh goat's milk and long-term aerobic exercise increased calcium levels and decreased CTx-1 levels. Therefore, the combination of both therapies reduces bone resorption, and fresh goat's milk is allowed to be consumed regularly as a sports nutrition to reduce the risk of premature osteoporosis in athletes.

Vascular Responses to Acute Induced Inflammation With Aging: Does Fitness Matter?

Acute inflammation impairs vascular function in an age-dependent manner and affects cardiovascular event risk. Regular aerobic exercise preserves vascular function with aging and potentially modifies how acute inflammation affects the vasculature. We hypothesize high cardiorespiratory fitness may accompany greater arterial responsiveness post-acute inflammation in older adults.

Exercise-induced β-hydroxybutyrate promotes Treg cell differentiation to ameliorate colitis in mice.

Increasing attention is being paid to the mechanistic investigation of exercise-associated chronic inflammatory disease improvement. Ulcerative colitis (UC) is one type of chronic inflammatory bowel disease with increasing incidence and prevalence worldwide. It is known that regular moderate aerobic exercise (RMAE) reduces the incidence or risk of UC, and attenuates disease progression in UC patients. However, the mechanisms of this RMAE's benefit are still under investigation. Here, we revealed that β-hydroxybutyrate (β-HB), a metabolite upon prolonged aerobic exercise, could contribute to RMAE preconditioning in retarding dextran sulfate sodium (DSS)-induced mouse colitis. When blocking β-HB production, RMAE preconditioning-induced colitis amelioration was compromised, whereas supplementation of β-HB significantly rescued impaired β-HB production-associated defects. Meanwhile, we found that RMAE preconditioning significantly caused decreased colonic Th17/Treg ratio, which is considered to be important for colitis mitigation; and the downregulated Th17/Treg ratio was associated with β-HB. We further demonstrated that β-HB can directly promote the differentiation of Treg cell rather than inhibit Th17 cell generation. Furthermore, β-HB increased forkhead box protein P3 (Foxp3) expression, the core transcriptional factor for Treg cell, by enhancing histone H3 acetylation in the promoter and conserved noncoding sequences of the Foxp3 locus. In addition, fatty acid oxidation, the key metabolic pathway required for Treg cell differentiation, was enhanced by β-HB treatment. Lastly, administration of β-HB without exercise significantly boosted colonic Treg cell and alleviated colitis in mice. Together, we unveiled a previously unappreciated role for exercise metabolite β-HB in the promotion of Treg cell generation and RMAE preconditioning-associated colitis attenuation.

Regular Intermittent Aerobic Exercise Reduces Arterial Stiffness Associated with Postprandial Hyperglycemia in Middle-Aged and Older Individuals

Hardening of arterial walls associated with elevated postprandial blood glucose levels increases the risk of cardiovascular disease; however, the impact of intermittent aerobic training on reducing arterial stiffness is unknown. The aim of this study was to examine the chronic effects of intermittent aerobic exercise on arterial stiffness during hyperglycemia in middle-aged adults: 30 healthy middle-aged adults were randomly assigned to an 8-week intermittent aerobic training group (n = 15, jogging or running, 30 min/run, 3 times/week, 65% reserve heart rate) and a control group (n = 15, no training). Pulse wave velocity (PWV) of carotid-femoral (cf) and brachial-ankle (ba), heart rate, blood pressure, and blood glucose was measured before a 75 g oral glucose tolerance test (OGTT) and 30, 60, and 90 min after the test, before the exercise intervention, and 4 and 8 weeks after intervention. The baPWV and blood glucose levels before the intervention were elevated at 30, 60, and 90 min in both groups compared to levels before the 75 g OGTT (p &lt; 0.01). The baPWV and blood glucose levels after 4 and 8 weeks of intervention were unchanged in the training group compared to that before the 75 g OGTT, but increased at 30, 60, and 90 min in the control group compared to that before the 75 g OGTT (p &lt; 0.01). The baPWV and blood glucose levels at 30 and 60 min after the 75 g OGTT after 4 and 8 weeks of intervention were lower in the training group than in the control group (p &lt; 0.01). These results indicate that intermittent aerobic exercise training may reduce the acute increase in arterial stiffness after hyperglycemia.

The intensity paradox: A systematic review and meta-analysis of its impact on the cardiorespiratory fitness of older adults.

The present systematic review and meta-analysis aimed to compare the effect of moderate- versus high-intensity aerobic exercise on cardiorespiratory fitness (CRF) in older adults, taking into account the volume of exercise completed. The databases MEDLINE (Ovid), EMBASE (Ovid), and CENTRAL (Cochrane Library) were searched to identify randomized controlled trials (RCTs). Two reviewers extracted data and assessed bias. Comprehensive Meta-Analysis software calculated overall effect size, intensity differences, and performed meta-regression analyses using pre-to-post intervention or change scores of peak oxygen uptake (V̇O2 peak). The review included 23 RCTs with 1332 older adults (intervention group: n = 932; control group: n = 400), divided into moderate-intensity (435 older adults) and high-intensity (476 older adults) groups. Meta-regression analysis showed a moderate, but not significant, relationship between exercise intensity and improvements in V̇O2 peak after accounting for the completed exercise volume (β = 0.31, 95% CI = [-0.04; 0.67]). Additionally, studies comparing moderate- versus high-intensity revealed a small, but not significant, effect in favor of high-intensity (Hedges' g = 0.20, 95% CI = [-0.02; 0.41]). Finally, no significant differences in V̇O2 peak improvements were found across exercise groups employing various methods, modalities, and intensity monitoring strategies. Findings challenge the notion that high-intensity exercise is inherently superior and indicate that regular aerobic exercise, irrespective of the specific approach and intensity, provides the primary benefits to CRF in older adults. Future RCTs should prioritize valid and reliable methodologies for monitoring and reporting exercise volume and adherence among older adults.

Effects of Regular Aerobic Exercise on Cardiovascular Health Factors and Heart Function in Sedentary Male Office Workers

OBJECTIVES This study aimed to investigate the effects of regular aerobic exercise on cardiovascular health factors and heart function in sedentary male office workers.METHODS To achieve this aim, 20 individuals were selected as subjects: 10 in the exercise group (who have been regularly exercising for over 5 years, more than 4 times per week, for 1 hour or more per workout) and 10 in the control group (defines sedentary behavior more of moderate-intensity exercise for 30 minutes or longer, at least three days a week ). For data processing, the average and standard deviation were calculated using the SPSS 21.0 statistical program, and the difference in the mean value change between groups was verified by performing an independent t-test.RESULTS There were significant differences between groups in factors related to cardiovascular health, such as resting heart rate, maximum systolic blood pressure, maximum oxygen intake, and exercise duration. Regarding heart function, there were significant differences between both groups in peak velocities of early and atrial fillings, as well as in early and late diastolic annulus velocities.CONCLUSIONS Taken together, regular aerobic exercise appears to have a positive impact on cardiovascular health factors and heart function in sedentary male office workers.