Registration Of Patient Data Research Articles

Variation in blood pressure and heart rate of radiological technologists in worktime tracked by a wearable device: A preliminary study

The aim of this preliminary study was to measure the systolic BP (SBP) and diastolic BP (DBP) and heart rate (HR) of radiological technologists by WD, and evaluate variation among individuals by worktime, day of the week, job, and workplace. Measurements were obtained using a wristwatch-type WD with optical measurement technology that can measure SBP and DBP every 10 minutes and HR every 30 minutes. SBP, DBP, and HR data obtained at baseline and during work time were combined with the hours of work, day of the week, job, and workplace recorded by the participants in 8 consecutive weeks. We calculated the mean, the ratio to baseline and coefficient of variation [CV(%)] for SBP, DBP, and HR. SBP, DBP, and HR values were significantly higher during work hours than at baseline (p<0.03). The ratio to baseline values ranged from 1.02 to 1.26 for SBP and from 1.07 to 1.30 for DBP. The ratio to baseline for SBP and DBP showed CV(%) of approximately 10% according to the day of the week and over the study period. For HR, ratio to baseline ranged from 0.95 to 1.29. The ratio of mean BP to baseline was >1.2 at the time of starting work, middle and after lunch, and at 14:00. The ratio to baseline of SBP were 1.2 or more for irradiation, equipment accuracy control, registration of patient data, dose verification and conference time, and were also working in CT examination room, treatment planning room, linac room, and the office. CV(%) of BP and HR were generally stable for all workplaces. WD measurements of SBP, DBP, and HR were higher during working hours than at baseline and varied by the individuals, work time, job, and workplace. This method may enable evaluation of unconscious workload in individuals.

Abstract OT2-5-01: Brain metastases in breast cancer network Germany (BMBC, GBG 79): Multicentric, retro- and prospective collection of patient data and biomaterial from breast cancer patients with brain metastases

Abstract Background: The incidence of brain metastases in breast cancer patients is rising and has become a major clinical challenge in the last years. So far, limited therapeutic options and insights into the biology of brain metastases exist. Most reports include patients with brain metastases from different tumor entities and few studies so far analyzed exclusively patient data or tumor samples from breast cancer patients. In this context, an open, multicenter registry and biobank should be helpful for analysis of a large number of breast cancer patients with brain metastases. Therefore, we initiated the Brain Metastases in Breast Cancer Network Germany (BMBC; GBG79). Trial design and eligibility criteria: Patients with brain metastases from breast cancer are eligible. Registration of patient data is allowed retrospectively and prospectively. To enable an easy access, an internet-based database was chosen ("MedCodes" by the German Breast Group). Specific aims: Documented data cover incidence, symptoms, number and localization of brain metastases, histopathology, imaging methods, outcome, therapy, and quality of life measurement. Tissue of brain metastases and primary tumors will be collected for translational research projects. Planned analyses include treatment patterns in Germany, patient outcome, as well as validation of prognostic scoring systems in a multicenter setting and in the context of new targeted therapies. Translational research projects investigate the impact of glycosylation, resistance mechanisms against HER2-targeted therapies, role of the blood brain barrier, evaluation of markers of radioresistance and specific genomic alterations associated with brain tropism of breast cancer cells. The registry and biobank should be also open for cooperation with other groups. Present accrual and target accrual: The accrual target is app. 1000 patients in the database and app. 400 tissues of brain metastases from German centers. The study was opened for documentation in April 2014 with more than 50 participating centers as of June 2014. Citation Format: Isabell Witzel, Elena Laakmann, Tanja Fehm, Volker Möbus, Gunter vonMinckwitz, Julia Kaiser, Sibylle Loibl, Volkmar Müller. Brain metastases in breast cancer network Germany (BMBC, GBG 79): Multicentric, retro- and prospective collection of patient data and biomaterial from breast cancer patients with brain metastases [abstract]. In: Proceedings of the Thirty-Seventh Annual CTRC-AACR San Antonio Breast Cancer Symposium: 2014 Dec 9-13; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2015;75(9 Suppl):Abstract nr OT2-5-01.

OP060: Virtual 3D maxillary tumor marking – Exact intraoperative coordinate mapping improve post-operative radiotherapy – Technology, principal consideration and clinical implementation

Background The quality of the interdisciplinary interface in oncological treatment between surgery, pathology and radiotherapy is mainly dependent on reliable anatomical three-dimensional (3D) allocation of specimen and their context sensitive interpretation which defines further treatment protocols. Computer-assisted preoperative planning (CAPP) allows for outlining macroscopical tumor size and margins. A new technique facilitates the 3D virtual marking and mapping of frozen sections and resection margins or important surgical intraoperative information. These data could be stored in DICOM format (Digital Imaging and Communication in Medicine) in terms of augmented reality and transferred to communicate patient’s specific tumor information (invasion to vessels and nerves, non-resectable tumor) to oncologists, radiotherapists and pathologists. Aim The purpose of this work was to develop, establish and clinically evaluate a novel, user-friendly, language independent and multidisciplinary tool to provide intraoperative collected data to the surgeon, oncologist, radiotherapist, pathologist and radiologist. Methods 19 Patients where operated with the support of computer assisted surgery. Time needed for preoperative planning including data transfer, dataset alignment, automatic and manual object segmentation, trajectories and additional safety checkups was measured in minutes. Accuracy of our set-up was recorded after registration. Finaly surgical time and Quality improvements were evaluated by comparison of hard and soft-tissue and the deviation of the correct position of the preplaned implants with the postoperative results was compared. Results Successful preoperative planning, import of image data suitable for navigation and intraoperative precise infrared-based navigation was obtained for all patients without any complications. The registration of patient data at the navigation system using screws as fiducial markers delivered a navigation accuracy with a mean deviation of 1.3 ± 0.6 mm in our cases. The novel method of intra-operative marking of specimen either frozen sections or surgical margins eases the storage and further use of intra-operative information. Image-guided navigation technique for head and neck oncologic surgery provides a precise, safe surgical method with real time excellent anatomic orientation. Conclusion Regarding the advantages of computer-assisted surgery, this technique will play a major part in craniofacial reconstructive surgery and will address widespread general methodological solutions that are of great interest in multidisciplinary oncologic treatment.

Psykiatrisk patientsregistrering Det psykiatriske centralregister i Danmark. En analyse af kritikken for og imod

Psychiatric research increasingly includes manual and computerized registration of patient data. There has been a fear of violation of the integrity of the individual, for which reason a law has been passed. The fear is prevalent in Norway and has resulted in abolition of a continuous registration in the Central Register. This article deals primarily with Danish conditions of the Psychiatric Central Register in Aarhus (DPC). The DPC is accumulative and an identification index. The criticism of the DPC in the Danish daily press has thrown light on many essential issues concerning psychiatric patient registers. Meanwhile, the criticism has not been objective. It is uniform and incorrect, with insistence on abolition or limitations of the DPC. The balance between personal integrity and the needs of the community for registers is discussed. The article is in favor of a greater openness among laymen and internally in both the scientific press and the daily press.