Regions Of Serbia Research Articles

The epidemiology of road traffic injuries in the republic of Serbia: a study based on hospital data, 2015-2019.

Road traffic injuries (RTI) are the leading cause of death and severe disability among individuals under the age of 40, posing a significant public health challenge globally. This manuscript highlights key aspects of the epidemiology of injuries in road traffic crashes (RTC) in Serbia, based on hospitalization report data. The main aim of this study was to analyze the epidemiological characteristics of road traffic injuries (RTI) based on hospital data over a five-year period in Serbia. The data for this study were obtained from the Hospitalization Report, which is part of the hospitalization database maintained by the Institute for Public Health of Serbia "Dr Milan Jovanović Batut," covering the period from January 2015 to December 2019. The research included data from the Hospitalization Reports of 66 healthcare institutions across Serbia. During the study period, a total of 15,028 patients with road traffic injuries were admitted to healthcare institutions in Serbia. During the five-year period, the crude RTI incidence rate increased every year, from 39.0/100, 000 in 2015 to 43.7/100,000 in 2019. Older adult people aged 65 and over were particularly vulnerable as bicyclists and pedestrians (31.3, 27.7%, respectively). The Vojvodina region experienced a higher incidence of injuries among bicyclists compared and car accidents were most frequent in Central Serbia than in the other regions of Serbia. Craniocerebral injuries were the most common type of road traffic injury, accounting for 37.8% of cases. Significant differences in the types of injuries were observed based on age (χ 2 = 649.859; p < 0.001) and gender (χ 2 = 31.442; p < 0.001). Understanding the epidemiological profile of road users involved in accidents is essential for monitoring and controlling specific risk factors. Our results highlight the need for enhanced traffic safety measures at the local level.

PCV2 AND PCV3 GENOTYPING IN WILD BOARS FROM SERBIA

Porcine circoviruses 2 and 3 (PCV2 and PCV3) are known agents of diseases in domestic pigs and wild boars. PCV2 is an economically important pathogen causing porcine circovirus-associated diseases (PCVAD), while the recently discovered PCV3 is associated with similar disorders. Wild boars can serve as a PCV reservoir for domestic pigs, which is a particular risk for pig farms with low biosecurity. Reports of these infections in Serbia are sporadic, and this study was intended as a follow-up to an earlier study. Our aim was to assess the prevalence and genetic characteristics of PCVs circulating in wild boars in a region in north-eastern Serbia with extensive hunting areas. In our study of 103 samples, 17.48% tested positive for PCV2 and 15.53% for PCV3. The low co-infection rates in 2.94% of the PCR-positive samples, suggests these viruses circulate independently. PCV2 prevalence was lower than in our previous study (40.32% out of 124 samples), but the genetic stability of circulating strains was detected with a clear genotype shift towards PCV2d-2. Moreover, this is the first report of PCV3 occurrence in wild boar in Serbia, and the detected strains were grouped into two genotypes: PCV3-1 and PCV3-3c. The PCV3-1 sequences were clustered with German strains, indicating the prevalence of this genotype in Europe. However, no further geographical correlation could be established, as the PCV3-3c representative was separated within the cluster containing Chinese and Indian strains. Furthermore, there was no correlation between PCV positivity and pathological findings in the sampled animals indicating subclinical infection.

Unlocking the Potential of the Elderly Population in Serbia: A Modeling Study on Musculoskeletal Disorders and Associated Factors.

Background/Objectives: A properly functioning musculoskeletal system is imperative for human well-being at every stage of life, including at an older age. This study's aim was to assess the relationship between sociodemographic and physical functioning variables and the presence of individual musculoskeletal disorders (MSDs), MSD comorbidity, and multimorbidity, as well as to determine factors that are independent predictors of the presence of MSDs in people over 65 years old. Methods: This population-based study included 3701 participants aged 65 years and older. Data on individual MSDs addressed cervical and lumbosacral spine regions and degenerative joint disease (arthrosis). The subjects were categorized into four groups: those without any diseases; those with one MSD; those with two MSDs (comorbidities); and those with three MSDs (multimorbidities). The sociodemographic and physical functioning variables were analyzed. Results: Females were more likely to have MSDs (two: OR 1.95 and three: OR 2.25) than men. Elderly people aged 75 and above were 1.49 times more likely to have three MSDs. Elderly people with elementary school education were more likely to have MSDs (two: OR 1.34 and three: OR 2.06) than those with high school/university education. The low-income population was 2.47 times more likely to have three MSDs. Individuals with partial activity limitations because of health problems had greater chances of having one, two, or three MSDs (OR 1.60, 1.59, and 1.94, respectively), and elderly individuals with severe limitations had an OR of 1.43, 2.17, and 4.12, respectively. Individuals with some/many difficulties in walking up or down 12 steps were more likely to have MSDs (two: OR 2.26 and three: OR 2.28). Conclusions: The significant predictors of experiencing a single MSD, MSD comorbidity, or MSD multimorbidity include residing in the Serbian capital city and having limitations in activities due to health problems. A significant predictor of having a single MSD or MSD comorbidity is residing in the northern region of Serbia. A significant predictor of MSD comorbidity is residing in the southeastern region of Serbia. Significant predictors of MSD comorbidity or MSD multimorbidity include female gender, an elementary school educational level, and experiencing difficulty in walking up or down 12 steps. Significant predictors of MSD multimorbidity are being 75 years of age and above and having a lower income.

Serbia multidisciplinary approach for surveillance and risk identification – The “One Health” information for action

Abstract Issue/problem To date, Serbia has not detected locally acquired Dengue cases. Since a competent Dengue virus vector Aedes albopictus (Ae. albopictus) has been detected since 2017, imported cases have the potential to trigger local transmission. Description of the problem To ensure preparedness and timely response in the event of an epidemic signal in Serbia, we described the imported Dengue cases and analysed the geographical distribution and density of the vector. Probable and confirmed imported cases meeting the 2018 EU case definition were reported via the National Notifiable System between January 2019 and December 2023. We monitored the density and geographical spread of mosquitos, including Ae. albopictus, which were collected during May-October 2022 and 2023. Mosquito genera were determined according to morphological criteria and DNA barcoding. Results During the investigation period, physicians reported three probable and four confirmed imported Dengue cases; the mean age was 28.4 (standard deviation (SD)=11.5) years and 57% were male. Cases had travelled in Southeast Asia (n = 6) and the Caribbean (n = 1). The mean time interval from symptom onset to seeking medical care was 3.6 (SD = 2.1) days and from symptom onset to laboratory confirmation 7.4 (SD = 6.3) days. We collected 1994 Ae. albopictus mosquitoes in 308 sampling sites across 12 Serbian regions. We observed the highest number of mosquitoes in September (38%, p &amp;lt; 0.001) and in the Belgrade region (81%, p &amp;lt; 0.001). In 2022, we detected Ae. albopictus mosquitos in seven regions and in 2023 in nine. Lessons Ae. albopictus mosquitoes were widely distributed in Serbia, with the highest presence during September and in the capital region. The importation of Dengue cases from affected countries underscores the need for enhanced integrated and “real-time” surveillance linked with vector control activities.

Inequities in the green transition: anti-mining protests in the European periphery

Supposed green technological fixes to the climate crisis necessitate the mining of raw materials such as lithium en masse, spurring the proliferation of mining globally and the associated social and ecological harms. Major economies are engaged in a resource race for critical raw materials that are indispensable inputs for electric vehicles and digital technologies in the green transition and fourth industrial revolution (Kalantzakos, 2020; Kalantzakos et al, 2023). As this race materialises, so too has resistance and contestation on the proposed mining sites. This article engages with the critical literature on ecologically unequal exchanges (Hornborg, 1998; 2014; 2016) and extractivism (Acosta, 2013) to explore protracted civil society resistance to two lithium mining projects in rural and agrarian regions of Serbia and Portugal. The European Union is pursuing a dual agenda of decarbonising personal use transport and resource autonomy in an increasingly shifting geopolitical order; in turn a massive effort for onshoring mining activities is underway in Europe. The author argues that recent policy enactments by the European Union for onshore mining produces ecological and social harms in rural and agrarian areas and is illustrative of an unequal ecological and economic exchange. Agrarian and subsistence livelihoods are affected in pursuit of green technological solutions, highlighting the contradictory character of the green transition under capitalism and ultimately advocates for a degrowth position.

Impact of Vitamin D Status and Nutrition on the Occurrence of Long Bone Fractures Due to Falls in Elderly Subjects in the Vojvodina Region of Serbia.

Bone fractures are a significant public health issue among elderly subjects. This study examines the impact of diet and vitamin D status on the risk of long bone fractures due to falls in elderly subjects in Vojvodina, Serbia. Conducted at the University Clinical Center of Vojvodina in autumn/winter 2022-2023, the study included 210 subjects >65 years: 105 (F: 80/M: 15) with long bone fractures due to falls and 105 (F: 80/M: 15) controls. Groups were similar regarding age and BMI. Dietary intakes (by two 24-h recalls) and serum vitamin D levels were analyzed. The fracture group had a significantly lower median daily vitamin D intake (1.4 μg/day vs. 5.8 μg/day), intake of calcium, energy, proteins, fats, fibers, dairy products, eggs, fish, edible fats/oils, and a higher intake of sweets (p < 0.001 for all). Serum vitamin D levels were significantly lower in the fracture group (40.0 nmol/L vs. 76.0 nmol/L, p < 0.001). Logistic regression identified serum vitamin D as the most important protective factor against fractures, and ROC curve analysis indicated that serum vitamin D levels > 50.5 nmol/L decreased fracture risk. Nutritional improvements (increased intake of vitamin D and protein sources such as fish, eggs, and dairy), increased sun exposure, and routine vitamin D supplementation during winter are advised.

Wine – The Favourite Beverage of Serbian Medieval Rulers and Nobility

Wine, as the most noble and beloved drink of the Middle Ages, was primarily consumed in the courts of Serbian medieval rulers and nobility. During the early decades of the 14th century, Serbian rulers and nobles imported wine from the coastal cities of Zeta, which were under Serbian rule and where viticulture was the main agricultural production. The nobility from Serbian lands gravitating towards the Adriatic Coast (Trebinje and Hum) during the 14th and 15th centuries imported wine from the region of Dubrovnik, which represented the largest producer of this drink on the eastern coast of the Adriatic Sea. By the first decades of the 15th century, viticulture had reached a higher level of development even in the inner Serbian regions, especially in the vicinity of urban settlements, enabling rulers and nobility to have access to larger quantities of domestic wine. During visits and stays in Dubrovnik, Serbian rulers and regional lords were often honored with generous amounts of wine. This drink was almost invariably present at rulers’ and nobility’s banquets, organized for various occasions, but also as a form of everyday socializing and entertainment, where toasts were raised with glasses of wine in hand. The military dignitaires and soldiers also consumed wine during military campaigns. It is assumed that various types of red wine were more commonly consumed, among which the well-known kratošija from the Budva area and tamjanika from the Dubrovnik region, the latter also being cultivated as a white variety. White wine was considered more luxurious, such as trebbiano wine from Dubrovnik, wine from the Itailian town of Ortona, as well as the particulary esteemed malvasia, which Serbian and Bosnian rulers imported from Dubrovnik and Venice in the late 14th and the first half of the 15th century. In the summer months, wine was consumed chilled with ice, while during winter, pure wine was consumed. At the ruler’s court, a servant or cupbearer was responsible for the wine, referred to during the period of the Serbian Empire (1346–1371), as enohijar, a term of Greek origin. The person overseeing the servant and other courtiers in the ruler’s court held the title of grand servant, which was granted to members of the most prestigious noble families. Large quantities of wine were stored in fortresses near the ruler’s court or in special cellars called vinice or pivnice. Rulers and nobles’ tableware for pouring and drinking wine was made from precious metals, mostly silver. For pouring wine, vessels known as bokal, bardak, imbrik, kondir, možul, and others were used, with the goblet, glass and cup being especially favored among the wine glasses.

Overview of the Implementation of the First Year of Immunization against Human Papillomavirus across Different Administrative Units in Serbia and Montenegro.

Despite the availability of a safe and effective vaccination, uptake of human papillomavirus (HPV) vaccination remains low worldwide. We aimed to analyze the coverage of HPV immunization during the first year of the immunization program and the sociodemographic characteristics across different administrative units in Serbia and Montenegro. Coverage of HPV vaccination in Serbia for females aged 9-14 and 15-19 years was 5.5% and 5.9%, respectively. The coverage rate of immunization against HPV in Montenegro for girls aged 9-14 years was 22.1%. Within Serbia, only one administrative region (Moravica) had HPV immunization coverage in girls 9-19 years old above 10%, 11 districts had coverage from 5 to 10%, while 13 districts had coverage below 5%. As per Montenegro, two administrative units, Cetinje and Berane, reported the highest coverage, with 39% and 36.4% of vaccinated eligible girls, respectively. When we explored the coverage of HPV immunization among girls aged 9-19 years across different regions in Serbia, we observed that the level of coverage did not correlate with the number of pediatricians or with the population density. In Montenegro, we observed a similar situation. On the other hand, we noticed a statistically significant moderate negative correlation (r = -0.446; p = 0.026) between HPV immunization coverage and the percentage of illiterate women in the administrative units. Comparing the coverage between the two countries we found that the higher coverage in Montenegro corresponded with a smaller number of female populations aged 9-14 years, with higher average net monthly income, with smaller population density and smaller number of pediatricians, among divorced persons, and among those without formal education or incompletely primary education. Taking into account the experiences in Montenegro, increasing immunization coverage in Serbia could be achieved through a more vigorous educational campaign targeting schools, the general population, and healthcare workers as well as by additionally incentivizing those engaged in these activities.

Characteristics of Patients with Sarcoidosis with Emphasis on Acute vs. Chronic Forms-A Single Center Experience.

Sarcoidosis is a granulomatous disease of unknown etiology that can affect almost any organ. Although the acute form can have spontaneous regression, a certain number of patients can have a chronic form, which leads to an increase in mortality and a decrease in the quality of life. Considering that the risk factors are still unknown, we wanted to compare the characteristics of patients with acute and chronic forms of sarcoidosis in Serbia in order to determine significant differences between them with hopes of contributing to everyday clinical practice. A total of 2380 patients treated in our clinic were enrolled in this study. They were separated into the following two groups: 1126 patients with acute form and 1254 patients with chronic form. They were further compared by gender, smoking status, radiological status, exposition, biomarkers for sarcoidosis, organ involvement, and other comorbidities; the distribution of patients according to regions of Serbia was also noted. Statistical significance was found in radiological findings (p < 0.001), biomarkers (calcium in 24 h urine p < 0.001; chitotriosidase p = 0.001), and the affliction of organs (p < 0.001). The differences noted in this paper could help improve our understanding of this disease.

Value Added in Irrigated Contrary to Rainfed Corn Production

Abstract Occurred climate change and incurvation of weather patterns globally brings unpredictable production in many economic sectors, especially agriculture, or closely in crop production. In this circumstances, rainfed crop production in many countries used to become old-fashioned system of production, while implementing irrigation tends to be reality that provides long-term food security and farms’ profit stability. The main goal of research is to economically justify the appliance of irrigation in conventional corn production at the farm level. In research used dataset corresponds to South Banat region in Serbia, while used method assumes calculation of contribution margin. Comparing the values of gross financial results gained in corn growing organized in similar production conditions, but with or without applying the irrigation, achieved results show its rise for almost six times after implementing the irrigation systems. Besides, overall profitability in rainfed corn production shows much higher sensibility towards the change in obtained incomes and variable costs.

Aquatic Insects (Ephemeroptera, Plecoptera and Trichoptera) Metric as an Important Tool in Water Quality Assessment in Hilly and Mountain Streams

The aim of the study was to test the significance of the EPT index in the water quality assessment of three types of water bodies in hilly and mountainous region of Serbia. The aquatic macroinvertebrate community was dominated by the group of insects, of which 95 taxa represent the EPT group. We compared the obtained values of biological indices used for the assessment of water quality according to the national legislation with the overall status assessment represented by the ecological quality classes (EQC). The results of the Spearman correlation test showed a negative correlation of EQC with the EPT index, BMWP score, H′, total number of taxa and number of sensitive taxa, while a positive correlation was observed for the values of SI and Tubificinae %. The values of EQC and biological indices were subjected to principal component analysis (PCA). The results showed that the parameters that contributed most to the differences were the EPT index, the BMWP score and the number of sensitive taxa. The results indicate that the EPT index is an excellent indicator of changes in water quality and an important tool for the ecological categorization of water bodies in mountain regions.

Hydrochemical Characteristics and Suitability Assessment of Groundwater Quality for Irrigation

The hydrochemical properties of groundwater play a crucial role in crop growth and soil health, as well as the maintenance of irrigation equipment. To ensure suitable water quality for irrigation, the present study was conducted to evaluate the hydrochemical properties of irrigation groundwater in a typical agricultural region of Serbia. Groundwater was sampled at three monitoring locations in the Srem region in Republic of Serbia between 2011 and 2020. Examined parameters included electrical conductivity (EC), total dissolved salts (TDS), pH values, and the concentrations of cations (sodium (Na+), calcium (Ca2+), magnesium (Mg2+) and potassium (K+)) and anions (bicarbonate (HCO3−), chloride (Cl−), sulfate (SO42−), and nitrate (NO3−)). Further assessment was done using three classification systems; Nejgebauer’s, the US USSL, and the FAO classification. To obtain a more detailed assessment, additional indices were included, such as Soluble Sodium Percentage (SSP), Sodium Adsorption Ratio (SAR), Residual Sodium Carbonate (RSC), Permeability Index (PI), Kelly’s Ratio (KR), Magnesium Adsorption Ratio (MAR), and Total Hardness (TH). The PCA analysis detected that the concentration of K+, Ca2+, and Na+ in the irrigation water were lower in recent years, while the concentration of Cl− was higher. The cluster analysis grouped the parameters into three clusters; I—electroconductivity, II—dry residue and HCO3−, and III—other water parameters for all three monitoring localities. According to the applied classifications, the majority of underground water samples were suitable for irrigation. However, some samples fell out of the range of the first class, indicating the need for regular water quality monitoring. In light of climate changes that influence water deficiency, the urgent need for wise and sustainable water use implies the application of a comprehensive approach to irrigation water quality assessment, as shown in this study.

The incidence of patients with pseudoexfoliation in two different regions of Serbia

Introduction/Objective. Pseudoexfoliation (PEX) is an age-related systemic disorder, which can affect the whole body, as well as the eye. It is characterized by abnormal production and accumulation of pseudoexfoliative material. When present in the eye, it can cause different difficulties, but most common are PEX glaucoma (XFG) and intraoperative and postoperative complications of cataract surgeries. The aim of this study was to determine an incidence of patients with PEX in two different regions of Serbia. Methods. The study included 7451 patients scheduled for cataract surgery in two regions of Serbia. It was designed as a multicentric, retrospective study with evaluation of the medical records of all patients who underwent cataract surgery. The study evaluated: incidence of PEX syndrome and PEX glaucoma, age, and sex of patients, as well as preoperative antiglaucomatous therapy and intraoperative and postoperative cataract surgery complications. Results. PEX syndrome (XFS)was recorded in 676 patients (407 females and 269 males), while 243 patients had XFS. It represented 3.26% of patients included in the study. Mean age of XFG patients was 78.1 ?} 2.1 years with a statistically significant difference (p &lt; 0.05) among incidence of XFG in females compared to males. Intraoperative and postoperative complications during cataract surgery were significantly common in patients with PEX (p &lt; 0.05) Conclusion. PEX can complicate cataract surgery, while on the other hand XFG is more difficult to treat and control than most other glaucomas. Therefore, patients with PEX require special treatment during follow-up and treatment.

Kvalitet semena lucerke iz različitih regiona Srbije u periodu čuvanja do 42 meseca

This study presents the findings from assessing the quality of alfalfa seeds collected from three Serbian regions: in each region, batches of seeds from six places were analyzed. The following criteria were investigated: the proportion of dormant seeds, the germinated seed content, the proportion of dead seeds, and the percentage of aberrant seedlings. Seed quality was assessed after six, eighteen, thirty, and forty-two months of storage. The highest seed quality was obtained after thirty and eighteen months of seed storage (91% and 89% of germination, respectively). During the 42-month storage period, the percentage of dead seeds (8%) and abnormal seedlings (7%) increased, while germination declined to 84%. In a storage period of six months, the participation of dormant seeds of 21% affected the germination rate, which was 77%, regardless of the low proportion of dead seeds (1%) and abnormal seedlings (2%).

KONCEPTUALIZACIJA DETINjSTVA U DETINjSTVU – PEDESETOGODIŠNjA BAŠTINA

Childhood – a children’s literature journal (Detinjstvo – časopis o književnosti za decu) has been published continuously since 1975 in Novi Sad in the Zmaj’s Children’s Games (Zmajeve dečje igre) edition. During its half a century of existence, six editors-in-chief and many more editorial teams have changed. On the pages of Childhood, texts of different nature were published, but all of them were dedicated to children’s literature and childhood, examining their various aspects. This text shows how criticism, evaluation of works of literature for children, actually evaluates the recipient itself, that is a child. It is also shown how the attitude towards the language of the literary work reflects the understanding of the child’s overall development, not only speech development. Insights into childhood and the child in older literature (for example, medieval) and oral tradition lead to a conclusion about the position of the child during the historical development of society. The image of childhood and children in different genres and in the works of different writers is most common on the pages of Childhood. It goes from the vision of an “ideal times” in which the “ornament of the world” flourishes, to the representation of a lonely child, left to itself and the terror of a consumer society in which it has the status of a “suppressed group”. The paper provides a broad framework that includes the concept of a child and childhood in a series of variations that are difficult to encompass. In such a widely covered synchronic and diachronic understanding of the child and childhood, in the Yugoslav, South Slavic and Serbian regions, but also in constant communication with general movements and knowledge, in the texts of different preoccupations (program texts, literary criticism and presentations, didactic texts), concepts of the child as an unfinished being and the child as an ideal and idealized projection of humanity are clearly observed, but also observed are the general value system of the culture, the national culture above all, and the culture of Western civilization with its essentially ambivalent attitude towards the child and childhood.

Popis 2022 - stanovništvo Srbije prema nacionalnoj pripadnosti

Ethno-demographic and ethno-statistical studies of the population of Serbia according to nationality are based on the census as the most important official source of data, which is held every ten years and provides information on demographic trends, the number and characteristics of all ethnic communities in Serbia, but also provides a database for the adoption of necessary measures population, social, economic, minority and other state policies important for the stable, even and prosperous development of the country. The paper highlights the impact of various factors on national declaration, as well as the buoyancy of this feature, whose subjectivity has influenced large fluctuations in the number of individual ethnic communities, as well as the accuracy and possibility of comparing census results. Changed census methodology, new methodological solutions, criteria, classifications, definitions, often as a result of national ideology, political decisions and social circumstances, had a great immediate impact on the changes in the population dynamics of all, and especially some nationalities. The paper analyzes the national composition of the population of Serbia (without Kosovo and Metohija) according to the data of the last census from 2011, as well as the significant demographic changes that occurred in the period between the two censuses (2011-2022), while looking at the similarities and differences between the regions. of Serbia (Belgrade region, Vojvodina region, Šumadija and Western Serbia region and Southern and Eastern Serbia region). The focus of the research is on the most important factors that influenced the change in the ethnic structure, such as differences in the rates of natural increase and migration balance according to nationality, but also ethnic alternation under the influence of numerous non-demographic, namely political, social, economic, religious, psychological and other factors. The different population dynamics of ethnic communities, i.e. the increase in the number and share of some, while at the same time the decrease in the number of others, determined the direction and intensity of changes and affected the national composition of the population, as well as the process of ethnic homogenization or dispersiveness of individual nationalities, which created and changed everything the ethnic image of Serbia.

Antibakterijska aktivnost etarskih ulja odabranih lekovitih biljaka na izazivače respiratornih infekcija u pedijatrijskoj populaciji

Acute respiratory infections (ARI) are the most common infectious diseases today and are the reason for as many as 75% of prescribed antibiotics in the world. For this reason, ARI is responsible for the emergence of bacterial resistance to the most commonly used antibiotics. The paper aimed to examine the potential antibacterial activities of the essential oil of medicinal plants Lavandula angustifolia Mill., Mentha spicata L., Chamomilla recutita (L.) Raushert, Salvia officinalis L., Urtica dioica L., from the region of southeastern Serbia, on bacteria associated with respiratory infections in the pediatric population. Relevant, dichotomous keys were used to determine the plant material. The extraction of the essential oil was performed with a Clevenger-type apparatus, while the antibacterial activity was examined with an aromatogram, using the disk-diffusion method. Statistical analysis was performed with a one-factor ANOVA test. The use of essential oils can be an alternative solution to combat multidrug-resistant bacteria. In our research, the oil of Salvia officinalis L. showed the strongest inhibitory effect against Moraxella sp., while the oil of Chamomilla Recutita (L.) Raushert showed the weakest effect against Haemophilus sp. In general, the essential oil of Chamomilla recutita (L.) Raushert showed the weakest effect against all isolated pathogens. The essential oil of the investigated plants can be used as a potential source of natural antibacterial compounds. Because of all the above, it is necessary to further investigate and identify the biologically active compounds of the investigated plants.

POSSIBILITIES OF SUSTAINABLE DEVELOPMENT OF SPORTS TOURISM IN SERBIA

The development of sports tourism in the modern age is linked to the concept of sustainability. Sports tourism is a specific form of tourism that involves the use of ecological, economic and social principles of sustainability. Recreational sports in today's conditions become an integral part of the lives of both people at home and those who go on trips, so tourist destinations have turned to the development and improvement of sports tourism. Destinations located in areas of rural development have enormous potential for the development of sports tourism, and they have the greatest potential if they are in the initial stages of development. Serbia is well-known in the world of sports, so the development of sports tourism can be recognized in neighboring countries and in other countries that have insufficiently used this market. It is Serbia that can provide education in the field of sports tourism to neighboring countries. The countries of the Western Balkans are undervalued in the context of tourism development, so in the coming period it is necessary to determine which elemental services would provide a faster incentive for more intensive development. For the purposes of this paper, research was conducted that will provide answers about the possibilities of sustainable development of sports tourism in Serbia. The total number of respondents is 200. The survey was conducted online and included all regions in Serbia.

Economic burden of breast cancer in northern Serbia.

Breast cancer is the most common cancer in terms of incidence and mortality among all cancers in women in Vojvodina, the northern region of Serbia. In addition to the effectiveness and safety of therapy, it is important to put emphasis on the cost of treatment, as well as on the optimal allocation of limited resources. This study aimed to assess the overall economic burden of breast cancer in Vojvodina, as well as the ratio of direct and indirect costs in 2019. Costs were estimated using Cost of Illness (COI) evaluation, from a social perspective, based on the prevalence of the disease. The total costs included both direct and indirect expenditures. Direct costs associated with breast cancer comprised expenses linked to screening, hospital treatment, outpatient care, and prescribed medications. Indirect costs were estimated using a human capital approach, encompassing expenditures tied to lost productivity arising from sick leave, early retirement, and premature death. The total cost of breast cancer in Vojvodina during 2019 was estimated to be 15 million euros. Among the total cost, direct costs accounted for 5 million euros, representing 34% of the overall expenses. Hospital treatment costs accounted for 76% of the direct costs, while screening costs represented 1%. Indirect costs amounted to 10 million euros, constituting 66% of the total cost. The primary driver was attributed to production losses caused by premature retirement, which accounted for 50% of the indirect costs. Breast cancer is a huge financial burden on both the health system and society in Vojvodina, accounting for 0.12% GDP. The dominance of indirect costs in total costs, can provide significant guidance to decision-makers in the healthcare system in terms of better allocation of limited resources to breast cancer prevention and early detection strategies.

Evidence of tick-borne encephalitis virus neutralizing antibodies in Serbian individuals exposed to tick bites.

Tick-borne encephalitis (TBE) is an emerging vector-borne and food-borne disease caused by the tick-borne encephalitis virus (TBEV; Orthoflavivirus encephalitidis), with a distribution spanning the Eurasian continent. Despite its significant public health impact in various European regions, TBE remains largely underdiagnosed in Serbia due to limited awareness and diagnostic challenges. In response to this, our study aimed to comprehensively assess TBEV exposure in individuals infested with ticks and to identify potential TBEV foci within Serbia. From 2019 to 2021, we conducted an observational study involving 450 patients who reported tick infestations. Our demographic analysis revealed a median age of 38 years, with a slight male predominance among the participants. We documented tick infestations in 38 municipalities across 14 districts of Serbia, with a notable concentration in proximity to Fruška Gora Mountain. The ticks most frequently removed were Ixodes ricinus, with nymphs and adult females being the predominant stages. On average, nymphs were removed after about 27.1 hours of feeding, while adult females remained attached for approximately 44.4 hours. Notably, we found age as a significant predictor of infestation time for both nymphs and adult females. Furthermore, we detected TBEV-neutralizing antibodies in 0.66% of the serum samples, shedding light on potential TBEV foci, particularly in Fruška Gora Mountain and other regions of Serbia. Our study emphasizes the urgent need for active TBE surveillance programs, especially in areas suspected of hosting TBEV foci, in order to assess the true TBE burden, identify at-risk populations, and implement effective preventive measures.