Tibet lies in the southwest border of the motherland and located in the hinterland of the Qing-Tibet Plateau, known as the “third pole of the world”. With the rapid development of tourism, the unbalanced development of regional tourism economy has become a common social and economic phenomenon., The paper Based on Tibet seven cities as the research object, in terms of the time and space, this dissertation analyzed the Tibet nearly a decade of tourism regional difference of tourism economy, with a series of analytical methods, such as range, standard deviation, extreme point and variable coefficient and so on. The result shows that the regional difference of Tibet tourism economy is evident. The absolute difference is enlarge unremmittingly, while the relative differences show a shrink trend in fluctuation. from the space tourism economy of Lhasa is well ahead of other cities in Tibet, The tourism economy of xigaze and Nyingchi are far behind of Lhasa, the tourism economy of Naqu and Ali are far behind of Lhasa from the space Lhasa, as the core of Tibet becomes the circle of tourism economic in Tibet. Then, according to the factor analysis method, evaluate seven cities in Tibet tourism to make Tibet tourism economy development level into four types, predevelopmental, rapid development, slow developmental and retarded development.