Regional Collaborative Networks Research Articles

Evolution of regional collaborative innovation network by the ‘two-wheel drive' of external proximity and endogenous gravity

ABSTRACT Collaborative innovation is the key support for promoting high-quality regional development. Taking Guangdong, Fujian and Zhejiang coastal city clusters as an example, this paper analyzes the evolution mechanism of collaborative innovation network based on the ‘two-wheel drive' perspective of external proximity and endogenous gravity. The results show that the difference of resource control ability among nodes in the network is decreasing, and the inverted ‘V’ structure with Xiamen and Putian as the main apex has evolved into a more robust ‘dual core’ (Fuzhou-Xiamen) radiation-type spatial structure. In addition, the evolution of regional collaborative innovation network is driven by ‘two wheels’. In external proximity, institutional proximity plays the strongest role in promoting, followed by geographical proximity, and the promoting role of technological proximity is gradually weakened. In the endogenous gravity, the influence of investment in science and education is strengthening, while the influence of the administrative level is declining.

Vietnam’s STEM Education Landscape: Evolution, Challenges, and Policy Interventions

In Vietnam, national policies increasingly prioritize STEM education, recognizing its critical role in developing future workforce skills. However, significant gaps remain between policy and practice. Currently, STEM education in Vietnam is primarily found in extracurricular activities, with limited systematic integration into the formal curriculum. Key challenges include inadequate teacher capacity, insufficient resources, sociocultural biases, and difficulties in translating national STEM goals into classroom practices. Future research should focus on several key areas to further strengthen STEM education in Vietnam. Evaluating effective curriculum models will help integrate STEM into the core curriculum more systematically. Assessing professional development programs will ensure that teacher training initiatives are effective and impactful. Addressing sociocultural biases is necessary to promote diversity and inclusion in STEM fields. Analyzing regional collaboration networks can identify best practices and foster knowledge sharing among ASEAN countries. Implementing context-specific reforms will ensure that solutions are tailored to the unique challenges and opportunities in Vietnam. Addressing these priorities will enable Vietnam to make informed decisions, strengthen STEM education, and develop a skilled workforce for sustainable economic growth.

Drifting towards multidimensional collaborative innovation: the co-evolution of collaboration networks and policy in China’s nuclear power industry

Purpose Nuclear power is a stable and reliable energy source that can improve energy structure while reducing carbon emissions, which is of great significance for environmental protection and combating climate change. As a unique industry, it is facing rare development opportunities in China and has broad market prospects. However, the characteristics of technical difficulty, loose organizational structure and uneven regional distribution limit the expansion of the nuclear power industry. This paper aims to a better understanding of the accumulation process for innovation capability from the perspective of network evolution and provides policy guidance for the market development of the nuclear power industry (NPI). Design/methodology/approach Methodologically, social network analysis is used to explore the co-evolution of multidimensional collaboration networks. First, the development and policy evolution of the NPI is introduced to divide the evolution periods. Then, the authors identify and analyze the core organizations, technologies and regions that promote nuclear power patent collaboration. Furthermore, three levels of collaboration networks based on organizations, technologies and regions are constructed to analyze the coevolution of patent networks in China’s NPI. Findings The results show that nuclear power enterprises always play the foremost role in the organizational collaboration network (OCN), and the dominance of foreign enterprises is replaced by Chinese state-owned enterprises in the third period. The technology hotspot has shifted from nuclear power plant construction to the control system. The regional collaboration network was initially formed in the coastal areas and gradually moved inland, with Guangdong and Beijing becoming the two cores of the network. The scale of three collaboration networks is still expanding but the speed has slowed down. Originality/value In response to the pain points of the NPI, this research focuses on multidimensional collaborative innovation, investigates the dynamic evolution process of collaborative innovation networks in China’s NPI and links policy evolution with network evolution creatively. The ultimate result not only helps nuclear power enterprises integrate innovative resources in complex environments but also promotes industrial upgrading and market development.

Inborn Errors of Immunity in Jordan: First Report from a Tertiary Referral Center.

Inborn errors of immunity (IEI) are a heterogeneous group of diseases with variable clinical phenotypes. This study was conducted to describe the epidemiology, clinical presentations, treatment, and outcome of IEI in Jordanian children. A retrospective data analysis was conducted for children under 15 years diagnosed with IEI from the pediatric Allergy, Immunology, and Rheumatology Division-based registry at Queen Rania Children's Hospital, Amman, Jordan, between 2010 and 2022. A total of 467 patients, 263 (56.3%) males and 204 (43.7%) females, were diagnosed with IEI. The mean age at symptom onset was 18 months (1 week to 144 months), a positive family history of IEI was reported in 43.5%, and the consanguinity rate was 47.9%. The most common IEI category was immunodeficiencies affecting cellular and humoral immunity at 33.2%, followed by predominantly antibody deficiencies at 16.9%. The overall median diagnostic delay (range) was 6 (0-135) months; patients with a positive family history of IEI had a statistically significant shorter diagnostic delay. Pulmonary and gastrointestinal clinical features were the most common at 55.2% and 45.6%, respectively. The overall mortality was 33.2%; the highest rate was reported in severe combined immunodeficiency at 56.2%. The high minimal estimated IEI prevalence at 16.2/100,000 Jordanian children compared to the regional and worldwide data, with the diversities in clinical presentation and distribution of IEI categories in our cohort point to unique features of IEI in Jordanian children, call for national registry establishment, regional and international collaborative networks.

Home-based management of hypoxaemic COVID-19 patients: design of the Therapy@Home pilot study

IntroductionDuring the COVID-19 pandemic, hospital capacity was strained. Home-based care could relieve the hospital care system and improve patient well-being if safely organised.We designed an intervention embedded in a regional...

Consensus-based indicators for evaluating and improving the quality of regional collaborative networks of intensive care units: Results of a nationwide Delphi study

PurposeTo select a consensus-based set of relevant and feasible indicators for monitoring and improving the quality of regional ICU network collaboratives. MethodsA three-round Delphi study was conducted in the Netherlands between April and July 2022. A multidisciplinary expert panel prioritized potentially relevant and feasible indicators in two questionnaire rounds with two consensus meetings between both rounds. The RAND/UCLA appropriateness method was used to categorize indicators and synthesize results. A core set of highest ranked indicators with consensus-based levels of relevance and feasibility were finally tested in two ICU networks to assess their measurability. ResultsTwenty-four indicators were deemed as relevant and feasible. Seven indicators were selected for the core set measuring the standardized mortality rate in the region (n = 1) and evaluating the presence, content and/or follow-up of a formal plan describing network structures and policy agreements (n = 3), a long-term network vision statement (n = 1), and network meetings to reflect on and learn from outcome data (n = 2). The practice tests led to minor reformulations. ConclusionsThis study generated relevant and feasible indicators for monitoring and improving the quality of ICU network collaboratives based on the collective opinion of various experts. The indicators may help to effectively govern such networks.

Regional Collaboration and Trends in Clinical Management of Thyroid Cancer.

This study examines the trends in the management of thyroid cancer and clinical outcomes in the Southwestern region of The Netherlands from 2010 to 2021, where a regional collaborative network has been implemented in January 2016. Retrospective cohort study. This study encompasses all patients diagnosed with thyroid cancer of any subtype between January 2010 and June 2021 in 10 collaborating hospitals in the Southwestern region of The Netherlands. The primary outcome of this study was the occurrence of postoperative complications. Secondary outcomes were trends in surgical management, centralization, and waiting times of patients with thyroid cancer. This study included 1186 patients with thyroid cancer. Median follow-up was 58 [interquartile range: 24-95] months. Surgery was performed in 1027 (86.6%) patients. No differences in postoperative complications, such as long-term hypoparathyroidism, permanent recurrent nerve paresis, or reoperation due to bleeding were seen over time. The percentage of patients with low-risk papillary thyroid carcinoma referred to the academic hospital decreased from 85% (n = 120/142) in 2010 to 2013 to 70% (n = 120/171) in 2014 to 2017 and 62% (n = 100/162) in 2018 to 2021 (P < .01). The percentage of patients undergoing a hemithyroidectomy alone was 9% (n = 28/323) in 2010 to 2013 and increased to 20% (n = 63/317; P < .01) in 2018 to 2021. The establishment of a regional oncological network coincided with a de-escalation of thyroid cancer treatment and centralization of complex patients and interventions. However, no differences in postoperative complications over time were observed. Determining the impact of regional oncological networks on quality of care is challenging in the absence of uniform quality indicators.

A study on the multidimensional driving mechanism of cross-regional scientific collaboration network in China

ABSTRACT Multidimensional proximity has been considered the important factor affecting regional scientific collaboration network (RSCN) and has received extensive attention from scholars. This paper constructs a cross-RSCN based on co-authorship across 31 regions in China, incorporates traditional multidimensional proximity and network embedding proximity into a unified framework and proposes a five-factor driving model for dissecting the mechanism of cross-regional scientific collaborative innovation (CI). The results show that the scientific collaboration network is gradually becoming saturated with connections, and the polarisation of cross-regional collaboration is increasingly serious. The collaboration intensity is affected by the co-movement of several proximity factors, among which geographic proximity (GP) is the main but not the sole one that positively affects the cross-regional scientific collaboration. Based on the decision tree model, we conclude that structure proximity may compensate for low GP and low economic proximity (EP) on cross-regional CI performance. The positive effect of network location proximity on regional scientific collaboration is more sensitive when the EP is not high. The findings provide significant guidance for scientific research institutions, universities and regional policy-makers to select appropriate partners as well as network embedding strategies, and further contribute to long-term improvement of scientific innovation performance and stable regional economic growth.

Structural Characteristics and Evolution Trend of Collaborative Governance of Air Pollution in “2 + 26” Cities from the Perspective of Social Network Analysis

The regional and complex air pollution problem has become a major bottleneck restricting the sustainable development of regional economies and societies. Constructing a regional collaborative governance network has become a key solution to solving the cross-regional air pollution problem. By performing a social network analysis, this paper analyzes the overall structure, internal characteristics, and evolution trend of the collaborative governance network of regional air pollution by selecting the data samples of the “2 + 26” cities from 2017 to 2021. The study found that the excellent results of air pollution control in Beijing–Tianjin–Hebei and its surrounding areas are due to precise and efficient collaboration among the “2 + 26” cities. The collaborative network formed by “2 + 26” cities based on the joint initiation of severe weather emergency responses is an important measure that can help to effectively control regional air pollution problems. There is a distinct difference in the collaborative pattern in the “2 + 26” cities air pollution collaborative governance model, showing a nested-difference network structure.

Preface by the Chairman of Organizing Committee of 4th ICCEE 2022

The organizing committee would like to extend a warm welcome to everyone who is attending and contributing to the “4th International Conferences on Civil and Environmental Engineering (ICCEE) 2022”. The theme of the conference is Toward Smart and Green Infrastructure for Achievement of Sustainability and Development Goals. The conference, held in Bali, Indonesia, aims to promote scientific and technological advancement, knowledge exchange, and cooperation among engineers and researchers in infrastructure development, civil and environmental studies, and other engineering-related fields.ICCEE 2022 is the fourth international conference held by the Departments of Civil Engineering and Environmental Engineering, following the successful 2010 conference attended by 260 participants, 284 participants in 2015, and 292 participants in 2019, all of whom were local and foreign participants. ICCEE 2022 is a continuation of the first, second, and third conferences, and it will provide opportunities for researchers to present and publish their research, as well as serve as a venue for strengthening national, regional, and international research collaboration networks for the Departments of Civil Engineering and Environmental Engineering. We will have one honorable keynote speaker and four invited speakers present during the day of plenary sessions. The parallel sessions will take place over the course of a single day, and 136 papers will be presented.We would like to thank the scientific committees, reviewers, all participants, keynote and invited speakers, presenters, and moderators for their contributions to this conference. Our thanks go to our sponsors: Centre of Technology Hasanuddin University, PT. Bosowa Beton Indonesia, PT. Amythas, PT. Adhi Karya Persero, PT. WIKA Beton, PT. Bumi Karsa, PT. Nindya Karya, PT Yodya Karya, and our co-organizers: Kyushu University, Universitas Udayana Bali, Politeknik Negeri Bali, Politeknik Transportasi Darat Bali, and Universitas Pendidikan Nasional.We sincerely hope that the 4th ICCEE 2022, themed “Toward Smart and Green Infrastructure for Achievement of Sustainability and Development Goals” will provide us with an invaluable opportunity to share knowledge and experiences. Dr. Eng. Muh. Akbar Caronge, S.T., M.Eng. Chairman of Organizing CommitteeList of Committee is available in this Pdf.

DD-06 SPIN (SURGICAL PRACTICES IN INCISIONAL HERNIA REPAIR). A NATIONAL TRAINEE-LED COLLABORATIVE MULTICENTRE PROSPECTIVE OBSERVATIONAL STUDY

Abstract Aim There is currently no established UK database establishing reliable outcome data for surgical repair of incisional herniae (IH). Their heterogeneity (variability in size, patient comorbidity, and multiple repair techniques) has resulted in no surgical management or outcome reporting consensus. This study aims to utilise national trainee led research collaboratives to perform a multi-centre, observational, prospective study to assess variation in IH defects (by utilising pre-defined criteria from The European Hernia Society (EHS) classification for IH and a Modified Ventral Hernia Working Group) and their subsequent operative management. This study will yield valuable, standardised data on variation in practice and outcomes (complications and 3 and 12-months follow-up) to provide a platform for expanding IH research. Materials and Methods All NHS hospitals in England undertaking elective IH repair will be eligible for inclusion. Dissemination of and recruitment to the study will be driven by regional research collaborative networks. This study will include all elective adult IH repairs with. Data will be collected and managed using REDCap electronic data capture tool. There will be three distinct phases comprising; The study is currently unfunded. Funds are sought to obtain NHS Trust sponsorship and proceed to phase 3 of the study.

A regional approach to reduce postoperative opioid prescribing in Ontario, Canada.

Opioid-related morbidity and mortality continue to rise in the province of Ontario. We implemented a provincial campaign to reduce the number of opioid pills prescribed at discharge after surgery in the Ontario Surgical Quality Improvement Network (ON-SQIN). Activities related to the provincial campaign were implemented between April 2019 and March 2020 and between October 2020 and March 2021. Self-reported data from participating hospitals were used to determine changes in postoperative opioid prescribing patterns across participating hospitals. A total of 33 and 26 hospitals participated in the provincial campaign in the first and second year, respectively. During the first year of the campaign, the median morphine equivalent (MEQ) from opioid prescriptions decreased significantly in a number of surgical specialties, including General Surgery (from 105 [75-130] to 75 [55-107], P < 0.001) (median, interquartile range) and Orthopedic Surgery (from 450 [239-600] to 334 [167-435], P < 0.001). The median number of opioid pills prescribed at discharge per surgery also decreased significantly, from 25 (15-53) to 15 (11-38) for 1 mg hydromorphone (P < 0.001) and 25 (20-51) to 20 (15-30) for oxycodone (P < 0.001). The decrease in opioid prescriptions continued in the second year of the campaign. Our approach resulted in a significant reduction in the number of postoperative opioids prescribed across a number of surgical specialties. Our findings indicate that evidence-based strategies derived from a regional collaborative network can be leveraged to promote and sustain quality improvement activities.

Research on Regional Collaborative Network Innovation and Enterprises’ Innovation Performance in the Sustainable Development of Yangtze River Delta, China

As one of the most dynamic and sustainable economic regions in China, Yangtze River Delta has been forming an innovation cluster of high-quality development. To explore the driving force during the integration of Yangtze River Delta, this article constructs a driving force model and makes an empirical study by the structural equation modeling method. The model proves that heterogeneity knowledge will positively affect innovation, that innovation performance has a strong positive impact on regional collaborative network innovation, that regional collaborative network innovation exerts a positive effect on knowledge spillover, and that organizational learning can affect innovation performance positively. Based on the above research results, some recommendations are proposed. Those recommendations consist of: (a) to forge a dynamic sustainable and innovative regional collaborative network system lay a foundation of high-quality development; (b) while the two driving forces of heterogeneity knowledge and organizational learning activated, the indices of enterprise innovation performance should be optimized.

How financial development scale and R&D influence regional innovation efficiency: empirical evidence from the financial industry.

Financial elements and R&D elements are significant drivers for enhancing regional innovation efficiency. This paper measures financial elements by financial development scale and the marketization level of the financial industry and R&D elements by the inputs and flow of R&D personnel and R&D capital and specifically considers R&D element flow to quantify the consequential spatial spillover effects. Based on provincial panel data from 2008 to 2018, the paper firstly estimates the regional innovation efficiency of China’s 30 provincial-level administrative regions using super-efficiency DEA and then conducts an empirical analysis of the influence of financial elements and R&D elements on regional innovation efficiency by the use of the Tobit model and three spatial econometric models. It is found that, by and large, the financial development scale, the marketization level of the financial industry, the inputs of R&D personnel and R&D capital, and R&D capital flow all have significant effects on regional innovation efficiency. Nonetheless, by region, R&D personnel flow in central China can significantly boost regional innovation efficiency while fails in eastern and western China. From the spatial perspective, both financial elements and R&D elements have significant positive spatial spillover effects. Therefore, in order to bolster regional innovation efficiency, it is crucial to improve the allocation of financial elements and R&D elements and build a tight regional collaborative innovation network.

Variable coastal hypoxia exposure and drivers across the southern California Current

Declining oxygen is one of the most drastic changes in the ocean, and this trend is expected to worsen under future climate change scenarios. Spatial variability in dissolved oxygen dynamics and hypoxia exposures can drive differences in vulnerabilities of coastal ecosystems and resources, but documentation of variability at regional scales is rare in open-coast systems. Using a regional collaborative network of dissolved oxygen and temperature sensors maintained by scientists and fishing cooperatives from California, USA, and Baja California, Mexico, we characterize spatial and temporal variability in dissolved oxygen and seawater temperature dynamics in kelp forest ecosystems across 13° of latitude in the productive California Current upwelling system. We find distinct latitudinal patterns of hypoxia exposure and evidence for upwelling and respiration as regional drivers of oxygen dynamics, as well as more localized effects. This regional and small-scale spatial variability in dissolved oxygen dynamics supports the use of adaptive management at local scales, and highlights the value of collaborative, large-scale coastal monitoring networks for informing effective adaptation strategies for coastal communities and fisheries in a changing climate.

Hospital-based health technology assessment in Brazil: current experiences and challenges

Abstract In Brazil, there is no consensus on the concept of hospital-based health technology assessment (HB-HTA). There is great variability in the existing models and difficulty in evaluating their results—whether in respect of clinical decisions, quality of care, and hospital policy and management or in respect of optimizing the use of resources. This study aims to discuss the experiences of HB-HTA, its integration into the regulatory system for the adoption of new technologies into the Brazilian public (SUS) (Unified Health System), and its main challenges. During a workshop, a panel of specialists in HTA and/or HB-HTA was formed, representative of four different perspectives: (i) Health services and health technology assessment units, (ii) Academia, (iii) Secretary of State for Health, and (iv) the Federal SUS sector. This was followed by discussion, a preliminary consensus, contributions from the audience, a plenary session, and a final consensus. HB-HTA is not institutionalized, nor is it part of the regulation system for the adoption of new technologies in the SUS. The main challenges are the difficulties in creating qualified teams, financial support, and sustainability. The work of these bodies in respect of the evaluation of new technologies deserves further studies analyzing the relationship between the pressure for adoption from the hospital team and industry professionals and legal rulings. It is necessary to strengthen HB-HTA culture and implement this policy in hospital management, making assessment bodies a part of managerial and decision-making processes in hospitals, and develop regional collaborative networks and a national network of HTA.

Regional Supervision of Healthcare Institutions With a Focus on Antimicrobial Resistance

Background: Resistance to antibiotic drugs, also called antimicrobial resistance (AMR) is a serious threat to (public) health. Surveillance reports throughout the world show that formation and spread of highly resistant microorganisms (HRMOs) continues to be substantial. In The Netherlands, 10 regional collaborative networks on AMR have been established among healthcare institutions to mitigate the existing risks concerning HRMO by collaborative actions in antibiotic stewardship and infection prevention. Objective: We sought to determine whether the healthcare institutions in one of the regional collaborative networks in The Netherlands contribute adequately to reducing the risks of formation and/or spread of HRMO. Methods: The Health and Youth Care Inspectorate in The Netherlands visited 37 institutions in the region of Limburg (the southern province). The following healthcare sectors were included: hospitals (n = 5), rehabilitation clinics (n = 2), long-term care facilities (n = 5), homecare institutions (n = 4), mental healthcare institutions (n = 2), dental care clinics (n = 4), general practitioners (GPs; n = 10), municipal health services (n = 2) and healthcare facilities for mentally disabled people (n = 3). In each visit, 5 topics were addressed: antibiotic policy, infection prevention, information transfer, governance and collaboration in the region. Results and Conclusions: In general, the healthcare institutions had an adequate to good score. Good results were seen in antibiotic policy (ie, the use of diagnostic tools to avoid the use of antibiotics); information transfer among GPs and in homecare institutions; and infection prevention in homecare institutions and dental care clinics. Exceptions with inadequate scores were observed in several areas: absence of prescription guidance specifically for antibiotics in various sectors; infection prevention among GPs, and dental care clinics. In 4 cases (ie, 3 GPs and 1 dental care clinic), we stopped using the autoclave because of lack of proof of proper maintenance.Funding: NoneDisclosures: None

Fuzzy Principal Component Analysis Model on Evaluating Innovation Service Capability

This article mainly evaluates the regional innovation service capacity through the TOPSIS method. Firstly, a regional collaborative innovation network is constructed and the Yangtze River Delta region is selected for analysis. Secondly, an evaluation index is constructed for innovation service capability, fuzzy principal component analysis is used to refine quantitative and qualitative index data of innovation service capability, and the index weight is calculated. Then the region of the Yangtze River Delta is selected and TOPSIS method is used to assist in the effective decision-making process of the evaluation of innovative service capabilities. Due to the large amount of data in this article, MATLAB programming is used. Finally, through the comparative analysis of the results, countermeasures and suggestions are put forward from the perspective of the improvement of collaborative innovation service capabilities.

Early and late stages of Developmental Biology in Argentina

The history of science in Argentina is based on the enormous contribution that the great immigration of the 19th and 20th centuries produced in the country. The scientific and philosophical ideas and the role played especially by Italian scientists who arrived in the country produced a great impact on the different disciplines including Development Biology in emerging universities. The University of Tucumán pioneered the study of experimental biology, making important contributions to reproductive biology and to the early development of amphibians. The contribution of the Italian embryologist Armando Pisanó and the Argentinian Francisco D. Barbieri expanded the field to other universities and research centers located in Córdoba, La Plata, Bahía Blanca and Rosario. Given its strategic position, laboratories located in the city of Buenos Aires reached technological advances faster than others. Indeed, these laboratories saw the evolution from experimental biology to developmental genetics, renewing interest in this area. Currently, Developmental Biology brings together young researchers eager to consolidate regional and global collaboration networks that seek to help solve specific problems such as fertility, epigenetics, stem cells and tissue engineering.

Chinese Stroke Association guidelines for clinical management of cerebrovascular disorders: executive summary and 2019 update on organizational stroke management

AimStroke is characterised by high morbidity, mortality and disability, which seriously affects the health and safety of the people. Stroke has become a serious public health problem in China. Organisational...