Kidney cancer is a significant health concern worldwide, with early detection crucial for successful treatment outcomes. Recently, there has been an increasing focus on investigating affordable and non-intrusive methods for detecting cancer at its early stages. This proposed approach delves into the utilization of antenna arrays to identify kidney cancer. Specifically, antenna array with circular polarization has been crafted to identify tumors in the human kidney. This array design has been implemented using CST software, operating at 2.4 GHz. The antenna array having a dimension of 150 mm x 150 mm. The array consists of four-square patches each having a length of 30 mm and the spacing between the patches is preferred to be 20 mm for ensuring the mutual coupling. FR4 substrate is used with the relative permittivity 4.3 and 1.6 mm thickness. The axial ratio of the circularly polarized antenna is 0.9 dB at 2.4 GHz. The reflection coefficient S 11 = –30dB. The renal phantom in humans has been built with the kidney, adrenal gland, ureter, skin, fat, and muscle components to allow for precise simulation. Following that, four stages of cancer tumors were built employing all of the necessary qualities. For every stage of the cancer tumor, the reflection coefficient growth and resonance frequency shift are calculated. For the initial stages, the resonance frequency shift is very low. Consequently, the primary determinant of detection is the rise in S 11 . For 3rd and 4th stages of the tumor, there is a significant change in resonance frequency and increase S 11 , which facilitates identification. The calculated specific absorption rate (SAR) is a smaller amount than the safety thresholds, indicating that using this method is safe. Overall, this research points to a novel, easy-to-use method for kidney cancer screening. This method has the following benefits: it is non-invasive, safe, quick, affordable, and comfortable, and it emits no ionizing radiation during the measurement process. Furthermore, a range of output parameters such as gain, directivity, and polar radiation have been accurately computed.