Reductive Cyclodimerization Research Articles

Reductive cyclodimerization of chalcones: exploring the "self-adaptability" of galvanostatic electrosynthesis.

The "self-adaptability" of galvanostatic electrolysis was shown to assist a multistage unprecedented chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. The process, all involving the reductive events, delivered densely functionalized cyclopentanes featuring five contiguous stereocenters (25 examples, yields of up to 95%, dr values up to >20 : 1). Dedicated and combined experimental as well as electrochemical investigation revealed the key role of a dynamic kinetic resolution of the aldol intermediate for the reaction mechanism.

A [2 + 3] Reductive Cyclodimerization of Quinoline by SmI2.

Pyridine and its derivatives are rather difficult to reduce, and the products often undergo a very fast reoxidation to regain aromaticity. The reduction of quinoline by SmI2 results in an instantaneous [2 + 3] cyclization reaction, forming a bridged seven-membered ring within a polycyclic system.

ChemInform Abstract: Zinc‐Mediated Reductive Cyclodimerization of α,β‐Unsaturated Aryl Ketones under Aqueous Conditions.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Intermolecular Reductive Cyclodimerization of Cyclic α,β‐Unsaturated Ketones Promoted by a Low‐Valent Titanium Reagent: A Facile Synthesis of Some New Spiro Compounds.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

Intermolecular Reductive Cyclodimerization of Cyclic α,β-Unsaturated Ketones­ Promoted by a Low-Valent Titanium Reagent: A Facile Synthesis of Some New Spiro Compounds

The intermolecular reductive cyclodimerization reactions of cyclic α,β-unsaturated ketones such as 2-benzylideneindan-1-ones, 2-benzylidene-1-tetralones, 3-benzylidenechroman-4-ones, and 3-benzylidenethiochroman-4-ones induced by a low-valent titanium reagent were studied. Some new spiro compounds were prepared in good yields under neutral and mild conditions. High stereoselectivity was achieved and the stereochemistry of the products was confirmed by X-ray diffraction analysis.

Zinc-Mediated Reductive Cyclodimerization of α,β-Unsaturated Aryl Ketones Under Aqueous Conditions

Zinc-mediated reductive cyclodimerization of α,β-unsaturated aryl ketones produces 3,4-trans-diarylcyclopentanols 2 regio- and stereoselectively in good yields in a 1:4 (v/v) mixture of saturated aqueous NH4Cl and tetrahydrofuran at room temperature.

Reductive cyclodimerization of arylmethylidenemalononitriles promoted by samarium and catalytic amount of iodine: facile synthesis of cyclopentene derivatives

Reductive cyclodimerization of arylmethylidenemalononitriles promoted by samarium and catalytic amount of iodine: facile synthesis of cyclopentene derivatives

Reductive cyclodimerization of arylmethylidenemalononitriles promoted by samarium and catalytic amount of iodine: facile synthesis of cyclopentene derivatives

Reductive cyclodimerization of arylmethylidenemalononitriles promoted by samarium and catalytic amount of iodine: facile synthesis of cyclopentene derivatives

Reductive cyclodimerization of arylmethylidenemalononitriles promoted by samarium and catalytic amount of iodine: facile synthesis of cyclopentene derivatives.

Samarium and a catalytic amount of iodine were used to obtain functionalized cyclopentenes by reductive dimerization followed by intramolecular cyclization of 1,1-dicyanoalkenes under mild conditions.

Reductive Cyclodimerization of Arylmethylidenemalononitriles Promoted by AlCl3/Sm System: A Facile Synthesis of Cyclopentamine Derivatives.

AbstractFor Abstract see ChemInform Abstract in Full Text.

Reductive Cyclodimerization of Arylmethylidenemalononitriles Promoted by Sm/InCl3×4H2O System in Aqueous Media: Highly Stereoselective Synthesis of Cyclopentamine Derivatives.

AbstractFor Abstract see ChemInform Abstract in Full Text.

Cyclodimerization of 1,1-dicyanoalkenes and arylidenecyanoacetates promoted by ytterbium diiodide

The reductive cyclodimerization of 1,1-dicyanoalkenes and arylidenecyanoacetates promoted by Ybl2 has been studied. Functionalized cyclopentenes are obtained in both high yields and stereoselectivity.

Reductive cyclodimerization of arylmethylidenemalononitriles promoted by AICI3/Sm system : a facile synthesis of cyclopentamine derivatives

Reductive cyclodimerization of arylmethylidenemalononitriles promoted by AICI3/Sm system : a facile synthesis of cyclopentamine derivatives

Reductive Cyclodimerization of α, β‐ Unsaturated Ketones Promoted by AlCl3/Sm System: A Facile Synthesis of 2‐Aroyl‐1,3,4‐triaryl Cyclopentanol Derivatives

AbstractPromoted by AlCl3/Sm bimetallic system, α, β‐unsaturated ketones underwent reductive cyclodimerization to afford cyclopentanol derivatives under mild conditions. The reaction is stereocontrolled and regioselective over the competitive carbon‐carbon double bond reduction.

ChemInform Abstract: Zinc‐Induced Novel Reductive Cyclodimerization of Some α,β‐Unsaturated Ketones.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

The crystal structure of a novel complex [Sm(HMPA) 3(H 20) 4] 3+3[I −] formed in the reductive cyclodimerization of linear α,β-unsaturated ketones by SmI 2

The samarium iodide/HMPA has been used to promote cyclodimerization of linear α,β-unsaturated ketones. A novel complex [Sm(HMPA) 3(H 2O) 4] 3+3[I −] ( 1) was isolated from the reaction and its X-ray crystal structure was determined. The Sm ion is hepta-coordinated displaying a pentagonal bipyramid geometry and an extensive hydrogen-bond network which keeps together the molecules in the crystal.

Nitroenamines - 7. Synthesis of 2, 5-bis-ω-aminoalkyl pyrazines through a novel reductive cyclodimerization

Nitroenamines - 7. Synthesis of 2, 5-bis-ω-aminoalkyl pyrazines through a novel reductive cyclodimerization