Purpose The present study covers simulation of blood flow in a roughness impact R test model to anticipate the hemodynamic conditions of adhesion of blood elements to the modified surface. It was performed using numerical modelling of this process. The aim of these simulations is to create a surface morphology that stimulates the adhesion of blood elements to the surface of base plate of impact R test. Methods The morphology of base plate of impact R test was developed using a vacuum powder sintering of commercial purity titanium powder (CP-Ti) on Ti6Al7Nb substrate. The finite volume method (FVM) and disperse particle method (DPM) were applied to develop the target model of a roughness impact R test. The morphology of modified surfaces was documented with digital microscope and SEM (scanning electron microscopy). Results The impact R test developed using the two phase blood model performed on regularly structured base plate resulted in shear stress values higher than the analogous for the model lacking such modification. The most significant reduction in maximum values of shear stress occurred in case of the DPM model and especially in the model with regular structures. Conclusions The proposed models are very effective in modeling of the analysis of blood flow in roughness impact-R test.