Image-guided reduction of intussusception is considered a radiologic urgency requiring 24-h radiologist and technologist availability. To assess whether a delay of 6-12h between US diagnosis and fluoroscopic reduction of ileocolic intussusception affects the success frequency of fluoroscopic reduction. Retrospective review of 0-5-year-olds undergoing fluoroscopic reduction for ileocolic intussusception from 2013 to 2023. Exclusions were small bowel intussusception, self-reduced intussusception, first fluoroscopic reduction attempt>12h after US, prior bowel surgery, inpatient status, and patient transferred for recurrent intussusception. Data collected included demographics, symptoms, air/contrast enema selection, radiation dose, reduction failure, 48-h recurrence, surgery, length of stay, and complications. Comparisons between<6-h and 6-12-h delays after ultrasound diagnosis were made using chi-square, Fisher's exact test, and Mann-Whitney U tests (P< 0.05 considered significant). Of 438 included patients, 387 (88.4%) were reduced in <6h (median age 1.4years) and 51 (11.7%) were reduced between 6 and 12h (median age 2.05years), with median reduction times of 1:42 and 7:07h, respectively. There were no significant differences between the groups for reduction success (<6 h 87.3% vs. 6-12h 94.1%; P-value = 0.16), need for surgery (<6h 11.1% vs. 6-12h 3.9%; P-value=0.112), recurrence of intussusception within 48h after reduction (<6h 9.3% vs. 6-12h 15.7%; P-value=0.154), or length of hospitalization (<6h 21:07h vs. 6-12h 20:03h; P-value=0.662). A delay of 6-12h between diagnosis and fluoroscopic reduction of ileocolic intussusception is not associated with reduced fluoroscopic reduction success, need for surgical intervention after attempted reduction, recurrence of intussusception following successful reduction, or hospitalization duration after reduction.