This paper presents a novel, to the best of our knowledge, high-speed transmission system that integrates a new structured light beam, specifically the perfect vortex Laguerre-Gaussian (PVLG) beam, with an optical code division multiple access (OCDMA) system utilizing a premutation vector (PV) code. The PVLG beams are distinguished by their unique shape, which remains nearly invariant during propagation regardless of the azimuthal order of the orbital angular momentum (OAM), facilitating the multiplexing of multiple OAM beams within the same spatial area. Additionally, the system employs hybrid multimode fiber (MMF) and free space optics (FSO) channels, with consideration of foggy weather conditions in the FSO channel. A comparative analysis between the performance of PVLG beams and standard LG beams is conducted. Performance evaluation metrics include the Q-factor, bit error rate (BER), and eye diagrams, providing comprehensive insights into received signal quality. The results demonstrate that the system utilizing PVLG beams outperforms the one using standard LG beams. Specifically, the system achieves a maximum MMF length of 0.35 km with a BER of approximately 10−4 and a Q-factor of around three when the MMF cable channel is used only. For the FSO channel, the achievable ranges are 1.1 km, 0.7 km, and 0.35 km under low fog (LF), medium fog (MF), and high fog (HF) conditions, respectively, maintaining the same BER and Q-factor values. Moreover, the hybrid MMF/FSO channel extends the transmission range to 1.2 km under LF conditions and to 0.45 km under HF conditions, with consistent BER and Q-factor values. Each of the four PVLG beams carries 40 Gbps, resulting in a total transmission capacity of 160 Gbps. Thus, the proposed system is well positioned to meet the high-speed data transmission demands of next-generation 6G networks.