The performic acid epoxidation of 4-methyloct-4-ene, a model compound for 1,4-polyisoprene, is the subject of this study. The purpose was the optimization of the conditions for the epoxidation reaction by this oxidation agent. The first part of this work is concerned with the identification and characterization of the reaction products through NMR and FTIR spectroscopies. Four main products were characterized. Among them, an epoxide results from the epoxidation of 4-methyloct-4-ene by performic acid and three others, namely a ketone, a diol and a glycol ester, are the result of epoxide rearrangements. The second part is devoted to kinetic studies of the epoxidation reaction through high performance liquid chromatography (HPLC) technique. This investigation allowed an insight into the influence of the reaction parameters (temperature and concentration of hydrogen peroxide) on the conversion rate. The determining step of the epoxidation reaction was the formation of performic acid. The enthalpy of activation was found to be ΔH ∗ = 91 kJ/mol and the entropy of activation ΔS ∗=−34.6 J/mol K.