Real-time QRS Detection Algorithm Research Articles

A Real-Time QRS Detection Algorithm Based on Energy Segmentation for Exercise Electrocardiogram

Motion artifact is widely present in exercise electrocardiogram (ECG) signal, which is an important factor affecting the accuracy of QRS complex detection. A simple-fast QRS detection algorithm based on energy segmentation is proposed, which is suitable for exercise ECG measured by the wearable monitoring device. The proposed method mainly consists of four parts: the 15–25 Hz band-pass filter, the calculation of segmentation energy, the moving average filter and the detection of R-peaks. To enhance the information of the QRS complex, a band-pass filter is used to eliminate noises and suppress unwanted P/T waves. The information of R-R interval and QRS duration is used to energy segmentation, and moving average filter is used to obtain the adaptive energy threshold. Then, an algorithm combined adaptive energy threshold with amplitude threshold is used for QRS detection. The MIT-BIH arrhythmia database and the European ST-T database are chosen to value the correctness of the algorithm. The motion artifact contaminated ECG database is chosen to value the robustness. Exercise ECG signals obtained by lab are used to value the practicality of the algorithm. The simulation results show that the QRS detection algorithm has a sensitivity of 99.36%, a positive predictivity of 99.78%, an accuracy of 99.14%, and performs well even under ECG signal contaminated by strong motion artifacts.

A 12-Bit Dynamic Tracking Algorithm-Based SAR ADC With Real-Time QRS Detection

A 12-bit successive approximation register (SAR) ADC based on dynamic tracking algorithm and a real-time QRS-detection algorithm are proposed. The dynamic tracking algorithm features two tracking windows which are adjacent to prediction interval. This algorithm is able to track down the input signal's variation range and automatically adjust the subrange interval and update prediction code. QRS-complex detection algorithm integrates synchronous time sequential ADC and realtime QRS-detector. The chip is fabricated in a standard 0.13 μm CMOS process with a 0.6 V supply. Measurement results show that proposed ADC exhibits 10.72 effective number of bit (ENOB) and 79.63 dB spur-free dynamic range (SFDR) at 10k Hz sample rate given 41.5 Hz sinusoid input. The DNL and INL are bounded at -0.6/0.62 LSB and -0.67/1.43 LSBs. The ADC achieves FoM of 48 fJ/conversion-step at the best case. Also, the prototype is experimented with ECG signal input and extracts the heart beat signal successfully.

A Real Time QRS Detection Algorithm Based on ET and PD Controlled Threshold Strategy.

As one of the important components of electrocardiogram (ECG) signals, QRS signal represents the basic characteristics of ECG signals. The detection of QRS waves is also an essential step for ECG signal analysis. In order to further meet the clinical needs for the accuracy and real-time detection of QRS waves, a simple, fast, reliable, and hardware-friendly algorithm for real-time QRS detection is proposed. The exponential transform (ET) and proportional-derivative (PD) control-based adaptive threshold are designed to detect QRS-complex. The proposed ET can effectively narrow the magnitude difference of QRS peaks, and the PD control-based method can adaptively adjust the current threshold for QRS detection according to thresholds of previous two windows and predefined minimal threshold. The ECG signals from MIT-BIH databases are used to evaluate the performance of the proposed algorithm. The overall sensitivity, positive predictivity, and accuracy for QRS detection are 99.90%, 99.92%, and 99.82%, respectively. It is also implemented on Altera Cyclone V 5CSEMA5F31C6 Field Programmable Gate Array (FPGA). The time consumed for a 30-min ECG record is approximately 1.3 s. It indicates that the proposed algorithm can be used for wearable heart rate monitoring and automatic ECG analysis.

A Real-time QRS Detector Based on Low-pass Differentiator and Hilbert Transform

Electrocardiogram(ECG) is an important physiological signal of the human body. It is widely used in identification and arrhythmia detection. The first step of ECG application is signal segmentation, that is, the QRS detection. An effective and real-time QRS detection algorithm is proposed in this paper. A differentiator with adjustable center frequency is used to capture the first derivative information of the frequency band of the electrocardiogram. Then Hilbert transform is used to generate the envelope of the first derivative. After that, a dual threshold method is introduced to decrease FP and FN. Finally, a more precise R wave position is determined based on derivative method. The detector is validated on MIT-BIH arrhythmia database. The result show that the proposed algorithm has a high Sensitivity of 99.87%, Specificity of 99.84%, and the detection error rate is 0.28%. The average execution time of a 30 minutes record is 2.45s.

Simple and Robust Realtime QRS Detection Algorithm Based on Spatiotemporal Characteristic of the QRS Complex.

The purpose of this research is to develop an intuitive and robust realtime QRS detection algorithm based on the physiological characteristics of the electrocardiogram waveform. The proposed algorithm finds the QRS complex based on the dual criteria of the amplitude and duration of QRS complex. It consists of simple operations, such as a finite impulse response filter, differentiation or thresholding without complex and computational operations like a wavelet transformation. The QRS detection performance is evaluated by using both an MIT-BIH arrhythmia database and an AHA ECG database (a total of 435,700 beats). The sensitivity (SE) and positive predictivity value (PPV) were 99.85% and 99.86%, respectively. According to the database, the SE and PPV were 99.90% and 99.91% in the MIT-BIH database and 99.84% and 99.84% in the AHA database, respectively. The result of the noisy environment test using record 119 from the MIT-BIH database indicated that the proposed method was scarcely affected by noise above 5 dB SNR (SE = 100%, PPV > 98%) without the need for an additional de-noising or back searching process.

Characterising an ECG signal using statistical modelling: a feasibility study

For clinical use, in electrocardiogram (ECG) signal analysis it is important to detect not only the centre of the P wave, the QRS complex and the T wave, but also the time intervals, such as the ST segment. Much research focused entirely on qrs complex detection, via methods such as wavelet transforms, spline fitting and neural networks. However, drawbacks include the false classification of a severe noise spike as a QRS complex, possibly requiring manual editing, or the omission of information contained in other regions of the ECG signal. While some attempts were made to develop algorithms to detect additional signal characteristics, such as P and T waves, the reported success rates are subject to change from person-to-person and beat-to-beat. To address this variability we propose the use of Markov-chain Monte Carlo statistical modelling to extract the key features of an ECG signal and we report on a feasibility study to investigate the utility of the approach. The modelling approach is examined with reference to a realistic computer generated ECG signal, where details such as wave morphology and noise levels are variable. References S. Edla, N. Kovvali, and A. Papandreou-Suppappola. Sequential Markov chain Monte Carlo filter with simultaneous model selection for electrocardiogram signal modeling. In 34th Annual International Conference of the IEEE EMBS, San Diego, California USA, 2012. doi:10.1109/EMBC.2012.6346915. A. Gelman, J. Carlin, H. Stern, and D. Rubin. Bayesian Data Analysis: Second Edition. Chapman and Hall/CRC, 2003. J. Hampton. The ECG Made Easy. Elsevier/Churchill Livingstone, seventh edition, 2008. C. Lin, C. Mailhes, and J.-Y. Tourneret. P- and T-wave delineation in ECG signals using a Bayesian approach and a partially collapsed Gibbs sampler. IEEE Transactions on Biomedical Engineering, 57(12):2840–2849, 2010. doi:10.1109/TBME.2010.2076809. P. E. McSharry, G. D. Clifford, L. Tarassenko, and L. A. Smith. A dynamical model for generating synthetic electrocardiogram signals. IEEE Transactions on Biomedical Engineering, 50(3):289–294, 2003. doi:10.1109/TBME.2003.808805. N. Metropolis, A. W. Rosenbluth, M. N. Rosenbluth, A. H. Teller, and E. Teller. Equation of state calculations by fast computing machines. The Journal of Chemical Physics, 21(6):1087–1092, 1953. doi:10.1063/1.1699114. G. B. Moody, R. G. Mark, and A. L. Goldberger. PhysioNet: a web-based resource for the study of physiologic signals. IEEE Engineering in Medicine and Biology, 20(3):70–75, 2001. doi:10.1109/51.932728. M. Niknazar, B. V. Vahdat, and S. R. Mousavi. Detection of characteristic points of ECG using quadratic spline wavelet transform. In Interrnational Conference on Signals, Circuits and Systems. IEEE, 2009. doi:10.1109/ICSCS.2009.5412588. J. Pan and W. J. Tompkins. A real-time QRS detection algorithm. IEEE Transactions on Biomedical Engineering, BME-32(3):230–236, 1985. doi:10.1109/TBME.1985.325532. K. Thygesen, J. S. Alpert, and H. D. White. Universal definition of myocardial infarction. Journal of the American College of Cardiology, 50(22):2173–2195, 2007. doi:10.1016/j.jacc.2007.09.011. U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER), Center for Biologics Evaluation and Research (CBER). Guidance for Industry E14 Clinical Evaluation of QT/QTc Interval Prolongation and Proarrhythmic Potential for Non-Antiarrhythmic Drugs, October 2005. http://www.fda.gov/downloads/RegulatoryInformation/Guidances/ucm129357.pdf. W. Zong, G. B. Moody, and D. Jiang. A robust open-source algorithm to detect onset and duration of QRS complexes. Computers in Cardiology, 30:737–740, 2003. doi:10.1109/CIC.2003.1291261. W. Zong, M. Saeed, and T. Heldt. A QT interval detection algorithm based on ECG curve length transform. Computers in Cardiology, 33:377–380, 2006. http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=4511867.

ECG-Multichannel Frontend for Quick Stimulus Response Based on FPGA with Implemented Real-Time, Online QRS Detection Algorithm

Abstract Nowadays, economic globalisation is one of the strongest influences in the field of bioelectronics. Due to this, a solid symbiosis is increasing between research and economics. Especially small and medium-sized businesses (SMBs) expect to become and remain a part of this symbiosis. The sector of medical biosignal processing demands effective, compact, low cost and low energy embedded systems that are capable to adapt to new conditions on the market. In this paper, a system solution for SMBs is described that comes with the above-mentioned factors. For this reason, an easily adaptable multichannel frontend as daughterboard combined with an open source, online, real-time QRS detection algorithm based on Field Programmable Gate Array (FPGA) was developed. 1 Introduction The strong influence of economics in the research and the rapid globalization progress has led to a symbiosis be-tween industry and research of similar directions. The efforts of SMBs are to become and remain a part of this symbiosis. The field of bioelectronics is one of the most important fields that offers possible market entry due to its enormous potential. Medical biosignal processing is a continuously growing area of bioelectronics that demands highest efficiency. It is crucial for systems in this sector to have the capabil-ity of constantly adapting to new conditions on the mar-ket. The optimal system should be effective, profitable, compact, energy efficient and also adaptable to new con-ditions without the loss of any of the abovementioned at-tributes. The experimental realization is carried out by a highly integrated, embedded system. FPGAs offer a very good platform for embedded systems. They are suitable for creating monitoring systems or can be very helpful for signal pre-processing for real-time da-ta-monitoring by reducing PC workload. The implementa-tion of algorithms on these embedded systems differ from other computer based monitoring systems. The architecture of an FPGA brings the ability of parallel processing and offers especially for complex algorithms a very high per-formance. This technology allows the parallel collection of data from ADCs without time multiplexing. Besides that, a great modular variety is given due to hardware pro-gramming. The following system solution for SMBs was developed considering these criteria.

Quantitative investigation of QRS detection rules using the MIT/BIH arrhythmia database.

We have investigated the quantitative effects of a number of common elements of QRS detection rules using the MIT/BIH arrhythmia database. A previously developed linear and nonlinear filtering scheme was used to provide input to the QRS detector decision section. We used the filtering to preprocess the database. This yielded a set of event vectors produced from QRS complexes and noise. After this preprocessing, we tested different decision rules on the event vectors. This step was carried out at processing speeds up to 100 times faster than real time. The role of the decision rule section is to discriminate the QRS events from the noise events. We started by optimizing a simple decision rule. Then we developed a progressively more complex decision process for QRS detection by adding new detection rules. We implemented and tested a final real-time QRS detection algorithm, using the optimized decision rule process. The resulting QRS detection algorithm has a sensitivity of 99.69 percent and positive predictivity of 99.77 percent when evaluated with the MIT/BIH arrhythmia database.