Replacing ordinary concrete in partially encased concrete (PEC) columns with high-strength and durability reactive powder concrete (RPC) significantly improves their axial capacity and suppresses local buckling of the steel section. To study the axial mechanical performance of partially encased composite reactive powder concrete (PEC-RPC) columns after exposure to high temperatures, axial compression tests of eight PEC-RPC column specimens were designed and conducted. Thermal response, failure modes, axial load-vertical displacement curves, and strain-axial strain curves of different specimens were observed considering the effects of link spacing, cross-sectional dimensions, constant temperature duration, and cooling methods. Results indicate: PEC-RPC columns exhibited whitening on the surface of RPC after high-temperature exposure, specimens with the largest link spacing experienced RPC peeling due to concentrated thermal stress, exacerbated by spraying water, which created a stress difference between the surface and the interior, resulting in RPC peeling. The deeper the thermocouple was embedded, the lower the measured temperature. Additionally, due to the significantly lower thermal conductivity of RPC compared to steel, the temperature at measurement points within the RPC is much lower than that at the steel web. The failure mode of PEC-RPC columns after axial loading was characterized by the crushing of RPC and local buckling of section steel. The larger the link spacing, the more prone it was to multi-layer buckling, and columns with larger cross-sectional sizes tended to exhibit shear failure. The characteristic value of mechanical performance showed higher sensitivity to cross-sectional dimensions, but relatively lower sensitivity to link spacing and constant temperature duration. As the cross-sectional dimensions increased from 150×150 mm to 250×250 mm, the peak load, residual bearing capacity, stiffness, and ductility increased by 72.51–164.86 %, 89.8–173.6 %, 61.85–151.47 %, and 13.72–31.46 %, respectively. Finally, based on partition constraint theory and superposition principle, a simplified method for calculating the axial mechanical performance of PEC-RPC columns after exposure to high temperatures was proposed.