Reaction Of Polyethylene Glycol Research Articles

Insight into the reactivity of aromatic-rich fractions co‑carbonized with polyethylene glycol for preparation of isotropic pitch with superior spinnability

Co‑carbonization of aromatic-rich distillate oil (HCTO-RF) with polyethylene glycol (PEG) is a reliable process to prepare isotropic pitch with superior spinnability for producing carbon fibers. In the study, HCTO-RF was fractioned into light fraction, middle fraction, and heavy fraction. The chemical structural features of each fraction and their co‑carbonization routes with PEG under the same reaction conditions were characterized and investigated. The results reveal that the light fraction was mainly composed of molecules containing one and two aromatic hexagonal rings with numerous longer alkyl side chains. The middle fraction was rich in less polycondensed two and three aromatic hexagonal ring compounds, which contained a certain number of naphthenic structures. The heavy fraction was mainly composed of four aromatic hexagonal ring compounds with higher condensation degrees and less short alkyl side chains. The co‑carbonization reaction of PEG and the three fractions proceed by the routes: the radicals produced from the homolysis of the CO and CC bonds of PEG molecules; the activation of the aromatic units triggered by abstracting hydrogen; the polycondensation of activated aromatic units. The heavy fraction exhibited the most availability for co‑carbonization reaction, followed by the middle fraction and the light fraction the worst.

Design and characterization of an in vivo injectable hydrogel with effervescently generated porosity for regenerative medicine applications

Injectable hydrogels that polymerize directly in vivo hold significant promises in clinical settings to support the repair of damaged or failing tissues. Existing systems that allow cellular and tissue ingrowth after injection are limited because of deficient porosity and lack of oxygen and nutrient diffusion inside the hydrogels. Here is reported for the first time an in vivo injectable hydrogel in which the porosity does not pre-exist but is formed concomitantly with its in situ injection by a controlled effervescent reaction. The hydrogel tailorable crosslinking, through the reaction of polyethylene glycol with lysine dendrimers, allows the mixing and injection of precursor solutions from a dual-chamber syringe while entrapping effervescently generated CO2 bubbles to form highly interconnected porous networks. The resulting structures allow preserving modular mechanical properties (from 12.7 ± 0.9 to 29.9 ± 1.7 kPa) while being cytocompatible and conducive to swift cellular attachment, proliferation, in-depth infiltration and extracellular matrix deposition. Most importantly, the subcutaneously injected porous hydrogels are biocompatible, undergo tissue remodeling and support extensive neovascularisation, which is of significant advantage for the clinical repair of damaged tissues. Thus, the porosity and injectability of the described effervescent hydrogels, together with their biocompatibility and versatility of mechanical properties, open broad perspectives for various regenerative medicine or material applications, since effervescence could be combined with a variety of other systems of swift crosslinking. Statement of significanceA major challenge in hydrogel design is the synthesis of injectable formulations allowing easy handling and dispensing in the site of interest. However, the lack of adequate porosity inside hydrogels prevent cellular entry and, therefore, vascularization and tissue ingrowth, limiting the regenerative potential of a vast majority of injectable hydrogels. We describe here the development of an acellular hydrogel that can be injected directly in situ while allowing the simultaneous formation of porosity. Such hydrogel would facilitate handling through injection while providing a porous structure supporting vascularization and tissue ingrowth.

The influence of reaction conditions on structural properties and swelling kinetics of polyurethane hydrogels intended for agricultural purposes

Polyurethane hydrogels were prepared in open and closed system, in reaction of polyethylene glycol (PEG) with different molar mass (2000, 6000 and 10,000 g/mol) and poly[(phenyl isocyanate)-co-formaldehyde] (PPIF) in order to investigate the influence of different synthesis conditions on the hydrogel structure and consequently swelling properties. The PEG molar mass was varied in order to investigate the correlation between PEG chain length, hydrogel hydrophilicity and absorption capacity. Scanning electron microscopy (SEM) and porosity studies have shown that hydrogels prepared in open system have cellular, sponge-like structure, while preparation in closed system have resulted in hydrogels with compact structure. Morphological differences were reflected on swelling kinetics and compressive properties. Swelling ratio in distilled water increases with increasing in PEG molar mass in both series, but swelling behavior of hydrogels synthesized in open system follows second-order kinetics and in closed system first-order kinetics, slower response in first 180 min, but greater capacity to retain water. Compressive modulus increases with increasing in PEG molar mass and has greater values for hydrogels synthesized in closed system. Granulated PU-PEG hydrogels have demonstrated ability to retain and deliver water in soil and contribute to tomatoes growth. Addition of hydrogel in 1 wt% in soil has resulted in higher and more developed plant. Applying the procedure of preparation in open and closed system using the same compounds give hydrogels with a different morphology, swelling and mechanical properties, which implies different application. However, comminution of both type of hydrogels to the level under the pore size, when the morphological differences disappears, give the granules (diameter around 2 mm) with the same swelling properties and potential application in agriculture.

Preparation and evaluation of novel water soluble nonionic monoesters with expected surface activity (Dept.P)

A novel five series of monoesters were prepared two series by reaction of oxypropylated 1, 6 hexane diol with two types of fatty acid chloride (lauroyl and palmi and three series by the reaction of polyethylene glycol (MWs = 400, 1500, 2000) with three types of fatty acid chloride (decanoyl, lauroyl and palmitoyl chloride)]. The unique structural features of these surfactants were confirmed by spectroscopic tools (IR- 'H NMR). These nonionic monoesters have been found to exhibit excellent surface active properties including surface tension, interfacial tension, critical micelle concentration (CMC), low foaming, emulsion stability, and wetting. Also good biodegradability in river water, stability to hydrolysis in acidic and alkaline media, solubilization and dispersant properties in disperse dye systems were determined and evaluated. The antimicrobial and antifungal properties of these prepared monoesters were measured and evaluated .A comparison studies were done between the chemical structures and surface properties of such compounds.

Preparation and evaluation of nonionic polyurethane polymers in improving the rheological properties and filtrate loss control of water base muds

Polyurethanes are special nonionic polymers which had a wide range of applications nowadays. The purpose of this work is to produce different nonionic polyurethanes by the reaction of polyethylene glycols with different molecular weights (4000, 6000, 10.000 and 20.000 g/mole) and toluene diisocyanate. The structures of the obtained polyurethanes were determined using molecular weight measurements, Fourier transform infrared spectroscopy (FTIR) and proton nuclear magnetic resonance (1H-NMR). The effect of the synthesized polyurethanes on the rheological properties of two drilling fluids was studied. The polyurethane polymers were influenced the filtrate loss of the drilling fluids in comparison to the blank. The results showed that the synthesized polyurethane nonionic derivatives were effective in enhancement of the shear thinning non-newtonian drilling fluids that following the modified power Law Model (Herschel Bulky Model). The other rheological properties of the formulated drilling water base muds including: apparent viscosity (AV), plastic viscosity (PV), yield Point (YP), and gel strength were improved considerably compared to the commercial formulation.

Synthesis of cleavable silicone surfactant for water-repellent application

Polymeric silicone-based surfactants were prepared by the reaction of polyethylene glycol, maleic anhydride, polydimethylsiloxane, silicone oil, titanium isopropoxide, and sodium hydrogen sulfite. These surfactants showed water-repellent properties when cleaved by different buffer solutions. The synergetic effect of silicone oil-based surfactants and siloxane-based surfactants was studied using different characterization techniques for the surfactants. The hydrophobic properties of cleaved silicone-based surfactants were studied by measuring the contact angle measurement. The polymeric silicone surfactants are stable in nature. The structures of various stages of reaction were confirmed by thin-layer chromatography, Fourier-transform infrared spectroscopy, ultraviolet spectra, and nuclear magnetic resonance analysis. The surface-active properties of surfactants like surface tension and critical micelle concentration as well as foaming and wetting characteristics were also studied. This water-soluble surfactant had low foaming properties and can be used in textile, agriculture, petroleum and paint industries. The cleaved form of silicone surfactant was used for water-repellent application in textile and paint industries.

IPN structured UV-induced peelable adhesive tape prepared by isocyanate terminated urethane oligomer crosslinked acrylic copolymer and photo-crosslinkable trifunctional acrylic monomer

In this paper, a linear isocyanate terminated urethane oligomer, polyethylene glycol modified isophorone diisocyanate oligomer (PEG-IPDI), was prepared by the reaction of polyethylene glycol and isophorone diisocyanate. It is mixed as a cross-linking agent with an acrylic copolymer composed of 2-ethylhexyl acrylate, butyl acrylate, methyl methacrylate, hydroxyethyl acrylate and acrylic acid to form a network pressure sensitive adhesive (PSA) through the reaction of isocyanate groups in PEG-IPDI with hydroxyl and carboxyl groups in acrylic copolymer chains. By blending this network PSA with a photo-initiator and a trifunctional acrylic monomer in a certain ratio, the UV-curable PSA was obtained. After uniformly coating it on the treated polyethylene terephthalate film, a UV-induced peelable PSA tape for a silicon wafer dicing process was prepared. The PSA network formed before UV irradiation was held together with another network produced by UV irradiation of the trifunctional acrylate monomer to give an interpenetrating network (IPN) structure. The results showed that this novel UV-curable PSA tape with IPN structure had strong peel strength before UV irradiation, and could meet the fixed requirements of silicon wafer cutting process. After UV curing, the peel strength was remarkably lowered due to the formation of IPN structure. Compared to those semi-IPN structured PSA tapes prepared with traditional multi-functional urethane acrylate oligomers, the adhesion performances of IPN structured UV peelable PSA tape prepared in this work were similar, but the remaining adhesive on the wafer after the release of the UV cured tape was greatly reduced.

Preparation of Polyurethane Silicon Oxide Nanomaterials as a Binder in Leather Finishing

Leather finishing processes using toxic organic solvent based produce volatile organic compounds (VOC), chronic exposure to this chemicals effect on workers' health causing many diseases especially lung cancer. So, polyurethane waterbased was synthesized for application in leather finishing instead of organic solvent based because it’s economic and safety for industry and workers. Preparation of water-based polyurethane (PU) depends on the reaction of polyethylene glycol (PEG, 300) with isophorone diisocyanate (IPDI) and the reaction of IPDI-1,4-butanediol (BDO) together with dimethylolpropionic acid (DMPA), was synthesized by poly-addition polymerization reaction. PU was then modified with different amounts of silicon dioxide nanoparticles (1-5 % SiO2), used as a binder in leather finishing. Leather coated was characterized physically, chemically and thermally by FTIR, GPC, DLS, TEM, SEM and TGA. The results revel that, water vapor permeability (WVP) of leather coated with PU modified with SiO2 showed improvement due to the existence of SiO2 particles which increases the interspaces of the polyurethane coating. SEM showed that when the amount of SiO2 nanoparticles increases, there is uniform nanoparticles accumulated can be observed. EDX prove the presence of Si and O2 elements and the formation of SiO2 nanoparticles. Mechanical properties discussed that tensile strength; tear strength and elongation at break % increase with increase SiO2 concentration until 3 % SiO2 nanoparticles. TGA showed an improvement of thermal stability of coated leather modified with SiO2. Therefore, this study succeeded in preparation of safe, ecofriendly of water-based polyurethane binders which modified with SiO2 for using in leather finishing.

Impact of synthesized amino alcohol plasticizer on the morphology and hydrophilicity of polysulfone ultrafiltration membrane

In this work, polysulfone (PSF) ultrafiltration membranes with increased hydrophilicity were prepared using the amino alcohol plasticizer (AAP). The AAP was synthesized by the reaction of polyethylene glycol (PEG) and isatoic anhydride (IAH). Different molecular weight of PEG and IAH (molecular weight 163Da) were used for preparing the AAP. Asymmetric membranes were fabricated by blending these plasticizers in membrane casting solution. Formation of AAP was confirmed by FTIR and 1HNMR spectra of AAP. Characterization of membranes was done in terms of hydraulic permeability, pure water flux (PWF) and hydrophilicity. PWF was found to be increased from 29.3L/m2h to 110.1L/m2h and water contact angle also reduced from 72° to 62° for plain and AAP containing PSF membrane, respectively. The morphological and structural analysis of the membranes was done by scanning electron microscope and field emission scanning electron microscope. Permeation and rejection behavior of fabricated membranes was studied by Bovine serum albumin (BSA) solution. Maximum BSA rejection was increased by 20.5% for the modified membrane. FESEM images affirm that the pore size of the membranes decreased by the addition of AAP. PEG with molecular weight of 400Da based AAP gave best performance among all the membranes for each parameter.

Investigation of the Local Environment of Hydrophobic End Groups on Polyethylene Glycol (PEG) Brushes Using Fluorometry: Relationship to Click Chemistry Conjugation Reactions on PEG-Protected Nanoparticles.

Targeted nanoparticles often require conjugating targeting ligands to polyethylene glycol (PEG) chains of a nanoparticle's dense protecting corona. "Click" chemistries are commonly employed for their bioorthogonality, with strain-promoted azide-alkyne cycloadditions (SPAAC) increasingly chosen to avoid cytotoxic copper catalysts. However, conjugation becomes compromised if reactive PEG chain ends cannot encounter their reaction counterparts. We use fluorescence to probe the location of Nile Red, methylpyrene, and butylpyrene, dyes with comparable hydrophobicities to SPAAC alkynes (logP = 3.2-5.7), tethered to PEG chains on 100 nm NPs. Using fluorescence peak shifts, we find that Nile Red resides 43% of the time in the 5k PEG corona and 57% at the more hydrophobic nanoparticle core. Increasing the PEG MW to 67k doubles the corona dye fraction to 86% (14% core). More hydrophobic methylpyrene and butylpyrene, monitored with I1/I3 ratios, reside 1% in the corona (99% core). These results explain difficulties with using SPAAC reactions for conjugating large ligands to nanoparticles with PEG coronae.

Preparation of Associative Polyurethane Thickener and Its Thickening Mechanism Research

Associative polyurethane (PU) thickener has been synthesized by preparing the prepolymer with the reaction of polyethylene glycol (PEG) and isophorone diisocyanate (IPDI), which then end‐capping with long‐chain alkanol. The synthesis process, as well as hydrophilic chain length, theoretical molecular weight, solvent ratio, and thickener percentages, has been researched. The results shows that it reaches the upmost thickening effect when the theoretical molecular weight is under 20000, soft‐segment length is under 4000, solvent ratio is 1 : 1, and thickener percentages are controlled at 10%. Furthermore, thickening mechanism of PU thickener has been analyzed detailedly through the measurement of the critical micelle concentration (CMC) of PU thickener and analysis of the influence of PU thickener on the particle size and morphology of PU dispersions. It has been observed from the scanning electron microscopy (SEM) that the PU aqueous dispersions produce a certain degree of flocculation when the PU thickener was added, and this flocculation structure has been proved to be a thixotropic structure through the characterization of the change of particle size before and after the thickener is introduced into the PU aqueous dispersions. The CMC measurement results present that the thickening effect will be apparent when the concentration is controlled in a low range.

Culture of preantral follicles in poly(ethylene) glycol‐based, three‐dimensional hydrogel: a relationship between swelling ratio and follicular developments

This study was undertaken to examine how the softness of poly(ethylene) glycol (PEG)-based hydrogels, creating a three-dimensional (3D) microenvironment, influences the in vitro growth of mouse ovarian follicles. Early secondary, preantral follicles of 2 week-old mice were cultured in a crosslinked four-arm PEG hydrogel. The hydrogel swelling ratio, which relates to softness, was modified within the range 25.7–15.5 by increasing the reactive PEG concentration in the precursor solution from 5% to 15% w/v, but it did not influence follicular growth to form the pseudoantrum (60–80%; p = 0.76). Significant (p < 0.04) model effects, however, were detected in the maturation and developmental competence of the follicle-derived oocytes. A swelling ratio of > 21.4 yielded better oocyte maturation than other levels, while the highest competence to develop pronuclear and blastocyst formation was detected at 20.6. In conclusion, gel softness, as reflected in swelling ratio, was one of the essential factors for supporting folliculogenesis in vivo within a hydrogel-based, 3D microenvironment. © 2014 The Authors. Journal of Tissue Engineering and Regenerative Medicine published by John Wiley & Sons, Ltd.

Synthesis and Characterization of Cholesterol-(1,2,3-triazole)-PEG via Click Chemistry

Firstly, toluenesulfonyl cholesterol was synthesized by the reaction of cholesterol and p-toluenesulfonyl chloride, and then reacted with sodium azide to obtain azido-cholesterol. Secondly, propargyl was introduced into the terminal groups of polyethylene glycol (PEG) by the reaction of PEG and bromine propargyl. Lastly, cholesterol-(1,2,3-triazole)-PEG oligomer was prepared by the reaction of the azido-cholesterol and propargyl-PEG via click chemistry using CuSO4.5H2O as a catalyst. The structures of the products were characterized by the FTIR and 1H NMR analysis.

Investigation on novel thermoplastic poly(urethane-thiourea-imide)s with enhanced chemical and heat resistance

A new generation of segmented thermoplastic poly(urethane-thiourea-imide)s (PUTIs) was synthesized via reaction of polyethylene glycol and thiourea-based prepolymer with dianhydride as chain extenders. NCO-terminated prepolymer was synthesized from a new diisocyanate, 3-(3-((4-isocyanatophenyl)carbamoyl)thioureido)phenyl-4-isocyanatophenylcarbamate (IPCT), as a hard segment and PEG forming soft segment. The starting materials and polymers were characterized by conventional methods and physical properties such as solubility, solution viscosity, molecular weight, thermal stability and thermal behavior were studied. PUTIs showed partially crystalline structures. Weight average molecular weights of PUTIs (GPC measurements) were in the range of 1,68,694–1,97,035. Moreover, thermogravimetric analysis indicated that poly(urethane-thiourea-imide)s were fairly stable above 500 °C having T 10 of 521–543 °C. Investigation of the results authenticated the approach of introducing thiourea (using IPCT) and imide structure in polyurethanes for the improvement of thermal stability. In comparison to typical polyurethanes, these polymers exhibited better heat resistance, chemical resistance as well as processability.

Synthesis of bis-triethoxysilane endcapped polyurethane/urea and its self-assembly morphologies with the assistance of hydrogen ion

A type of bi-triethoxysilane endcapped polyurethane/urea (SPU) with well-defined structure was synthesized through the reaction of polyethylene glycol (PEG), 2, 4-toluene diisocyanate (TDI) and bis-[trimethoxysiylpropyl]amine (DB-520). The structure of the resultant product was confirmed by Fourier transform infrared (FT-IR) and Nuclear magnetic resonance (1HNMR). Different SPU nanoparticles were obtained with the assistance of hydrogen ion, and their morphologies were characterized by combination of transmission microscopy (TEM) and FT-IR. The results showed that with increasing the concentration of hydrogen ions, the ratio of condensation accordingly increased, accompanying with the nanoparticle's morphology change from sphere to rod. Furthermore, the dispersion mechanism of SPU chains in protonic solution and the arrangement of molecular chains in hybrid particles were proposed. Copyright © 2011 John Wiley & Sons, Ltd.

Oxa-perfluoroalkyl end-capped PEG-based amphiphilic fluorocarbon polymer: synthesis and self-assembly behavior in water

Oxy-perfluoroalkylated end-capped polyethylene glycol (PEG) was synthesized by the reaction of PEG and polyethylene glycol monomethylether (PEG(MeO)) with trimer of hexafluoropropylene oxide (HFPO). The structures of the fluorinated polymers were characterized by 1H NMR, 19F NMR and FTIR. Their surface activities study shows that the fluorinated polymers have high surface activity. Core-shell micellization of the fluorinated polymers was inferred from the 19F NMR spectra derived in two different solvent environments (CDCl3 and D2O). Their self-assembly behaviors in water were studied in detail by pyrene fluorescence techniques, dynamic light scattering and scan electron microscopy. The results demonstrated that due to different fluorine content PEGF with two end-capped fluorocarbon groups can form large aggregates with the diameter size of about 132 nm, whereas PEG(MeO)F with only one-end-capped fluorocarbon groups forms small micelles with the size of round 12 nm.

GEMMA and MALDI-TOF MS of reactive PEGs for pharmaceutical applications

One of the most prominent polymer group applied for drug conjugation is poly(ethylene) glycol (PEG). Since drug production is subjected to strict restrictions on the part of the FDA and EMEA, also PEG has to be characterized accurately. Particularly its molecular mass distribution (MMD) and polydispersity can result in unrequested inhomogeneous final products. Therefore evaluation of PEG before applying it to drug conjugation is essential. In this study a new analytical method for size and molecular mass determination based on electrophoretic mobility called GEMMA is used to characterize linear PEGs with two differing terminating functional groups. To confirm the data acquired by GEMMA a second, well-established method for molecular weight determination, MALDI-TOF MS (matrix-assisted laser desorption ionization time-of-flight mass spectrometry), was applied. Utilizing these two analytical approaches four monomethoxylated PEG–succinimidyl succinate (mPEG–SS) derivatives were investigated in terms of polydispersity and MMD. Although based on differing principles, both analytical methods yield comparable results. All obtained MMD maxima for the mPEG–SS batches lie within the company stated specifications, MMD ± 10% (based on MALDI-TOF MS data). For mPEG–SS 2K a polydispersity of 1.02 and for mPEG–SS 5K, 10K and 20K a polydispersity of 1.01 were determined from GEMMA as well as from MALDI-TOF MS data and are in agreement with the company's data (based on GPC data), namely 1.05–1.10.

Adsorption behavior of rare earth elements using polyethyleneglycol (phosphomolybdate and tungstate) heteropolyacid sorbents in nitric solution

A new type of crystalline sorbent was prepared by the reaction of polyethyleneglycol (PEG) with phosphomolybdic (PMo) and phosphotungstic (PW) heteropolyacids. The morphology of the obtained sorbents was studied by X-ray diffraction (XRD) and scanning electron microscopy (SEM). It has been shown that a complexing reaction occurs between PEG and the heteropolyacids. By using these sorbents, the adsorption behaviors of rare earth elements in nitric solution were studied. The effects of temperature, contact time, nitric acid and initial metal ion concentration on the adsorption were investigated. In 0.1–5.0 mol L − 1 HNO 3, the adsorption percentage decreases with the increase of acid concentration. H,PEG400,PW and H,PEG400,PMo exhibited a different selectivity for rare earth metals, with H,PEG400,PW adsorbing in the order of La 3+ > Y 3+ > Pr 3+ > Gd 3+ > Sm 3+, and H,PEG400,PMo in the order of Y 3+ > La 3+ > Pr 3+ > Gd 3+ > Sm 3+. The experimental maximum adsorption capacities of the sorbents are in the range of 90–225 mg g − 1 for Y 3+, La 3+, Pr 3+, Sm 3+ and Gd 3+. In all cases, the maximum adsorption capacities of H,PEG400,PW are near to those of H,PEG400,PMo. The equilibrium data were evaluated according to the Freundlich and Langmuir isotherms and the Langmuir equation gave a better fit and modeled the adsorption well.

Synthesis of poly(ethylene glycol-b-styrene) block copolymers by reverse atom transfer radical polymerization

Reverse atom transfer radical polymerization (RATRP) of styrene (S) was carried out in bulk using polyazoester prepared by the reaction of polyethylene glycol with molecular weight of 3000 and 4,4′-azobis(4-cyanopentanoyl chloride) as initiator and CuCl2/2,2′-bipyridine (bpy) catalyst system to yield poly(ethylene glycol-b-styrene) block copolymer. The block copolymers were characterized 1H NMR, FT-IR spectroscopy and GPC. The 1H NMR, and FT-IR spectra showed that formation of poly(ethylene glycol-b-styrene) block copolymer. The polydispersities of block copolymers were observed between from 1.49 and 1.98 GPC measurements.

Preparation of some Ethoxylated Alkyl Sulfosuccinate Surfactants and Investigate their Mixed Solutions

Abstract A series of ethoxylated sodium monoalkyl sulfosuccinate (ESMASS) ester surfactants were prepared by reaction of polyethylene glycol (M. wt. 600) with sodium mono alkyl sulfosuccinate (SMASS). The esters were prepared by reaction of octyl, lauryl or cetyl alcohol with sodium sulfosuccinate (SSS) to prepare E(14)SMOSS, E(14)SMLSS and E(14)SMCSS. The chemical structures of the prepared surfactants were confirmed by FTIR and 1HNMR spectroscopy. The surface tension of the synthesized surfactants was measured at 25°C individually or mixing at different molar fraction with the sodium dioctyl sulfosuccinate. The surface active properties were calculated and micellization process of the mixture was investigated. The molar ratio of anionic (SDOSS) and anionic-nonionic surfactants moiety [E(14)SMOSS, E(14)SMLSS and E(14)SMCSS] in the mixed aggregates were deduced using the regular solution approximation equations. Depending on the critical micelle concentration values for each surfactant individually and mixed systems, the minimum surface tension was exhibited at mixture of [0.6 SDOSS and 0.4 E(14)SMCSS]. The micellar composition of the mixed aggregates were explained and discussed based on the effect of their chemical structures. Activity coefficient (f1, f2), interaction parameter (b) and ideality of anionic-nonionic mixed aggregates were evaluated.