Ratio Of Particles Research Articles

Phenotypic and genotypic features of children with familial hypercholesterolemia

Dyslipidemia is a metabolic disorder in which the ratio of lipid particles in the blood changes. It is often associated with other conditions and diseases during childhood. Lipid metabolism disorders in children can be divided into two categories: primary, which are inherited from parents or occur de novo, and secondary, which occur during life. Familial hypercholesterolemia is the most common type of primary disorder, characterized by an increase in blood lipoprotein levels. However, the lipid composition in children with established familial hypercholesterolemia can vary. One factor that may contribute to higher lipid levels in these children is the presence of mutations in the apolipoprotein E gene.Purpose of the study was to investigate the phenotypic and genotypic features of children with familial hypercholesterolemia in order to better understand this condition.Materials and methods. Children with a clinical diagnosis of familial hypercholesterolemia underwent DNA sequencing to identify mutations in genes related to LDLR, APOB, LDLRAP1, and APOE genes.Results. Children with familial hypercholesterolemia most often carry the polymorphism c.388T>C in the ApoE gene (g.45411941T>C, p.Cys130Arg, rs429358). Also, 24.1% of children were found to be isolated carriers of various ApoE haplotypes, which are risk factors for dyslipidemia. In children with a pathogenic mutation characteristic of familial hypercholesterolemia and carriage of polymorphisms in the ApoE gene, the LDL level was statistically higher compared to non-carriers.Conclusion. Carriage of various polymorphisms in the ApoE gene in children with familial hypercholesterolemia may lead to an increase in the already elevated levels of LDL and total cholesterol.

Infectivity of Hepatitis B Virus Surface Antigen-Positive Plasma With Undetectable HBV-DNA: Can HBsAg Screening Be Discontinued in Egyptian Blood Donors?

Hepatitis B Virus (HBV) infectivity data were reviewed and the 50% infectious dose (ID50) was reassessed in different HBsAg-positive infection stages enabling modelling of transfusion-transmitted (TT)-HBV infection risk if HBsAg donor screening was replaced by individual donation nucleic acid amplification technology (ID-NAT). Quantitative HBsAg and HBV-DNA assays were performed against international standards to compare the ratio between potential infectious HBV virions and subviral HBsAg particles in Egyptian HBsAg-positive blood donors as well as in Japanese chimpanzee samples of known infectivity. HBV-DNA load below the quantification limit of detection was estimated against a reference standard by replicate NAT testing (n = 25). Infectivity of chimpanzee samples collected during ramp-up and declining viremic phase were tested in a human liver chimeric mice (HLCM) model and compared with published infectivity data from different HBsAg-positive infection stages. Lowest estimates of ID50 in HBsAg-positive plasma were 3-6 HBV virions in chimpanzee studies. Infectivity decreased approximately 10-100-fold in the declining viremic phase using HLCM. In acute phase samples, HBV to HBsAg particle ratios varied between 1:102-104 but in HBsAg-positive blood donors this particle ratio reached 1:106-1012 when viral load was below 100 HBV-DNA copies/mL. Modelled TT-HBV risk of an HBsAg-positive/ID-NAT nonreactive blood transfusion was estimated at 5.5%-27% for components containing 20-200 mL of plasma when assuming an ID50 of 316 (point estimate between 100 and 1000) virions. It cannot be ensured that discontinuation of HBsAg donor screening and reliance on ID-NAT alone is safe.

Dynamic formation of gradient structure by microparticle impact — A crystal plasticity material point method study

Metallic materials with unique microstructure can achieve desirable strength-ductility synergy. However, effectively fabricating and precisely controlling microstructure distribution in metals remain challenging. Microparticle impact, the key process of cold spray technique, can lead to a gradient structure in the particle, which may also serve as a promising additive manufacturing technology. To investigate the dynamic formation mechanism of heterogeneous microstructure and its significant influencing factors, the crystal plasticity material point method (CPMPM) is developed, especially for microstructure formation under a high strain rate and large deformation. Our work provides a quantitative analysis of evolution of structural gradient during impact. It is found that decreasing grain size can afford a larger structural gradient and there is negligible influence on the compression ratio of particles. It suggests that microstructure distribution can be tailored by optimizing the impact process without influencing vertical deformation of particles.

A qualitative approach to describe the viscosity of flowable concrete made with manufactured sand containing different microfines

The concrete made with different manufactured sands can exhibit complex rheological properties. The prediction of viscosity is crucial in concrete placement, but remains challenging given the varied content and characteristics of microfines in the sands. This paper studies the influence of tuff (TF) and limestone (LS) microfines with disparate particle size distributions on the pseudo-Newtonian viscosity of concrete prepared with crushed sand. The concrete had a fixed water-to-binder mass ratio of 0.32 and polycarboxylate ether superplasticizer (PCE) dosage of 0.14 % by mass of biner. Test results showed that the microfines in manufactured sand can reduce the aggregate-to-excess cement paste ratio, leading to lower contact interactions between the aggregate grains. But the ratio of total powder particles and entrained air to excess interstitial solutions increased for the fluid paste matrix of the concrete, which caused greater flow resistance related to the powder contacts and air bubble deformations. A qualitative approach correlating the volume ratio of aggregate grains to excess cement pastes and that of total powder particles and entrained air to excess interstitial solutions was proposed to describe the pseudo-Newtonian viscosity of concrete, regardless of the different microfine additions in manufactured sand.

Optimising the feeding system for improving pellet distribution levels in gas-based shaft furnace based on the improved analytic hierarchy process

To improve the gas flow distribution inside the gas-based shaft furnace and ensure the chemical reaction, the discrete element method was used to calculate the effects of revolving chute inclination, particle size mass distribution, particle size distribution width, and hopper angle on the pellet distribution indicators (particle segregation, porosity, gas permeability and feeding time). An improved analytic hierarchy process was presented to fully analyse the nine schemes set up as part of the research. The findings demonstrated that the positive segregation of small particles at the furnace's centre and wall occurred with several feeding systems. The largest influences on porosity were differences in particle size mass distribution and particle size distribution width, and an increase in the proportion of small particles resulted in a significant decrease in porosity. The increase of the mass ratio of large particles made the highest permeability, but also caused uneven distribution of the furnace charge along the radial direction. The simulation results and the ranking of benefits and drawbacks produced by the improved analytic hierarchy process approach agree, demonstrating the applicability of the method to optimise the feeding system as well as its value in identifying the major influences on the feeding system.

Performance analysis of vertical smart isolator based on magnetorheological elastomer

ABSTRACT As one of the field-dependent smart materials whose stiffness and damping properties can change instantaneously and reversibly, magnetorheological elastomer (MRE) has been extensively utilized on base isolation for vibration reduction. However, most previous studies have focused on the shear dynamic performance of MRE isolators, and there are few reports on the vertical extrusion performance of basic isolators within construction equipment. In this paper, MRE materials with strong bearing capacity and suitable vertical stiffness were fabricated by comprehensively considering the selection of raw materials, particle ratio, and sample size. The tension-compression viscoelasticity of the prepared MRE under varying magnetic fields and strain amplitudes was experimentally evaluated using an MRE axial MR testing system. Eventually, a single-degree-of-freedom dynamic test rig for vibration isolation of equipment in buildings, which integrates a vertical isolator with MRE as the core component, was constructed to perform a series of experimental investigations on the alterable frequency vibration capability of the designed MRE vertical isolator. The test results reveal that the controllable stiffness-damping properties of the prepared MRE in the axial tension-compression mode can enable the developed vertical isolator to exhibit superior frequency shifting and vibration attenuating characteristics in structural vibration.

Strangeness production in sNN\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$ \\sqrt{s_{\ extrm{NN}}} $$\\end{document} = 3 GeV Au+Au collisions at RHIC

We report multi-differential measurements of strange hadron production ranging from mid- to target-rapidity in Au+Au collisions at a center-of-momentum energy per nucleon pair of sNN\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$ \\sqrt{s_{\ extrm{NN}}} $$\\end{document} = 3 GeV with the STAR experiment at RHIC. KS0\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$ {K}_S^0 $$\\end{document} meson and Λ hyperon yields are measured via their weak decay channels. Collision centrality and rapidity dependences of the transverse momentum spectra and particle ratios are presented. Particle mass and centrality dependence of the average transverse momenta of Λ and KS0\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$ {K}_S^0 $$\\end{document} are compared with other strange particles, providing evidence of the development of hadronic rescattering in such collisions. The 4π yields of each of these strange hadrons show a consistent centrality dependence. Discussions on radial flow, the strange hadron production mechanism, and properties of the medium created in such collisions are presented together with results from hadronic transport and thermal model calculations.

The Composition of the HDL Particle and Its Capacity to Remove Cellular Cholesterol Are Associated with a Reduced Risk of Developing Active Inflammatory Rheumatoid Arthritis.

In rheumatoid arthritis (RA), the risk of cardiovascular death is 50% higher compared to the general population. This increased risk is partly due to the systemic inflammation characteristic of RA and changes in the lipoprotein profiles. This study investigated plasma lipid levels, lipid ratios, and the composition and functionality of high-density lipoprotein (HDL) in control individuals and RA subjects based on the disease's inflammatory score (DAS28). This study included 50 control (CTR) individuals and 56 subjects with RA, divided into remission/low-activity disease (DAS28 < 3.2; n = 13) and active disease (DAS28 ≥ 3.2; n = 43). Plasma lipids (total cholesterol, TC; triglycerides, TG) and the HDL composition (TC; TG; phospholipids, PL) were determined using enzymatic methods; apolipoprotein B (apoB) and apoA-1 were measured by immunoturbidimetry. HDL-mediated cholesterol efflux and anti-inflammatory activity were assessed in bone marrow-derived macrophages. Comparisons were made using the Mann-Whitney test, and binary logistic regression was used to identify the predictors of active RA. A p-value < 0.05 was considered significant. TC, HDLc, and the TC/apoB ratio were higher in RA subjects compared to the CTR group. Subjects with active disease exhibited higher levels of TG and the TG/HDLc ratio and lower levels of HDLc, the TG/apoB ratio, TC, and apoA-1 in HDL particles compared to those with remission/low-activity RA. Increased levels of HDLc [odds ratio (OR) 0.931, 95% CI = 0.882-0.984], TC/apoB (OR 0.314, 95% CI = 0.126-0.78), HDL content in TC (OR 0.912, 95% CI = 0.853-0.976), PL (OR 0.973, 95% CI = 0.947-1.000), and apoA-1 (OR 0.932, 95% CI = 0.882-0.985) were associated with a decreased risk of active disease, but BMI (OR 1.169, 95% CI = 1.004-1.360) and TG (OR 1.031, 95% CI = 1.005-1.057) were positively associated with active disease. A reduction in HDL-mediated cholesterol efflux increased the OR for active RA by 26.2%. The plasma levels of HDLc, along with the composition and functionality of HDL, influence the inflammatory score in RA and may affect the development of cardiovascular disease.

Flattenicity as centrality estimator in p-Pb collisions simulated with PYTHIA/Angantyr

Abstract In this paper, a centrality estimator based on flattenicity is studied using PYTHIA~8.312 Angantyr, whose existing implementation is enough to study the particle production in p--Pb collisions in the absence of medium effects. The number of binary nucleon-nucleon collisions for different centrality estimators are compared. The studies include forward multiplicity, forward flattenicity and midrapidity multiplicity. The results using flattenicity show the smallest deviations ($&lt;8$\%) with respect to the results which use impact parameter for centrality classes. On the other hand, the multiplicity-based estimators exhibit huge deviations (up to a factor 2) with respect to the results using impact parameter. The particle ratios (proton-to-pion and kaon-to-pion ratios) and nuclear modification factors as a function of $p_{\rm T}$ are also studied for the different centrality estimators. The studies presented here are relevant to help in the investigation of the plethora of effects, which have been reported by experiments at the LHC.

Hybrid CoFe2O4-CNTs-graphene: Synthesis and characterization for energy storage devices

Hybrid materials play a crucial role in a spectrum of energy storage devices. Among them CoFe2O4–CNT–graphene hybrid stands out as versatile magnetic materials with wide-ranging applications spanning electronics, magnetism, and sensor industries. In this study, we synthesized CoFe2O4–CNT–graphene hybrid utilizing ultrasonication method. This fabrication method resulted in the formation of CoFe2O4 nanoparticles, along with bamboo-like carbon nanotubes (CNTs) and graphene nanosheets which collectively establish an open three-dimensional structure. Thorough analyses were conducted on the synthesized nano-composites employing various characterization techniques such as XRD, FT-IR, Raman and FESEM. Further characterization through XPS confirmed the formation of spinel ferrites, detecting the presence of carbon sp2, C1s, carboxylates (O-C-OH), and sp3 carbon, indicating the presence of carbon‑carbon (CC) bonds and confirms the energy levels of Co2p1/2 and Co2p3/2 indicating the effective incorporation of CFO onto the CNT/graphene surface. Analysis of dielectric parameters revealed promising characteristics for high-frequency devices, attributed to low dielectric loss, high quality factor, short relaxation time, and diverse responses exhibited by these materials. The M–H loops of the composite samples displayed ferromagnetic hysteresis behavior due to the presence of ferrite in the matrices. The coercivity value shows a slight improvement in the hybrid samples, while saturation magnetization values decrease, indicating a 1:1 weight ratio of ferrite particles to the host matrix with the incorporation of nonmagnetic CNTs and graphene, and the Hc value increases with the addition of these carbon-based materials due to increased surface anisotropy energy. Upon evaluation of dielectric and magnetic properties the hybrid materials demonstrated an enhanced dielectric and magnetic properties which render these materials suitable for utilization across a spectrum of energy storage devices.

Effects of Particle Size and Shape on the Texture Property of a Solid-Liquid Dispersion System With Gel Particles.

Food texture is one of the most important factors for assessing the quality and acceptability of food. However, the study of food texture has been delayed compared with other factors, such as flavor and taste, due to the difficulty of quantitative analysis related to real physiological senses. Furthermore, the numerical and systematic evaluation of the texture property of dispersion systems, in which solid particles are dispersed in a liquid medium, is very difficult, despite most foods being in a solid-liquid dispersion state during mastication in the human mouth. In this study, the texture property of a solid-liquid dispersion system with spherical and cubic gel particles of agar and konjac was examined to evaluate the physical behavior of food during mastication using the back extrusion method. The yield stress of the system strongly depended on the size and shape of the particles, the mixing ratio of particles of different sizes and shapes, and the concentration of components in the particles. The proposed index, reflecting the size, shape, and number of particles and the yield stress of a single particle, expressed well the measured yield stress of the entire dispersion system. However, the adhesiveness and recoverability showed relatively little dependence on particle size. The findings obtained in this study will contribute to elucidating the texture property of various foods and to the development of new and novel food products and cuisines, thereby benefiting food science and industry.

Shear Mechanism and Optimal Estimation of the Fractal Dimension of Glass Bead-Simulated Sand

Spherical glass beads weaken the influences of particle morphology, surface properties, and microscopic fabric on shear strength, which is significant for revealing the relationship between macroscopic particle friction mechanisms and the particle size distribution of sand. This paper explores the shear mechanical properties of glass beads with different particle size ratios under different confining pressures. It obtains the particle size ratio and fractal dimension D through an optimal mechanical response. Simultaneously, we explore the range of the fractal dimension D under well-graded conditions. The test results show that the strain-softening degree of Rs is more obvious under a highly effective confining pressure, and the strain-softening degree of Rs can reach 0.669 when the average particle size d¯ is 0.5 mm. The changes in the normalized modulus ratio Eu/Eu50 indicate that the particle ratio and arrangement are the fundamental reasons for the different macroscopic shear behaviors of particles. The range of the peak effective internal friction angle φ is 23 °~35 °, and it first increases and then decreases with the increase in the effective confining pressure. As the average particle size increases, the peak stress ratio MFL and the peak effective internal friction angle φ first increase and then decrease, and both can be expressed using the Gaussian function. The range of the fractal dimension D for well-graded particles is 1.873 to 2.612, and the corresponding average particle size d¯ ranges from 0.433 to 0.598. Under the optimal mechanical properties of glass beads, the particle size ratio of 0.25 mm to 0.75 mm is 23:27, and the fractal dimension D is 2.368. The study results provide a reference for exploring friction mechanics mechanisms and the optimal particle size distributions of isotropic sand.

Abundance measurements reveal the balance between lysis and lysogeny in the human gut microbiome.

The human gut contains diverse communities of bacteriophage, whose interactions with the broader microbiome and potential roles in human health are only beginning to be uncovered. Here, we combine multiple types of data to quantitatively estimate gut phage population dynamics and lifestyle characteristics in human subjects. Unifying results from previous studies, we show that an average human gut contains a low ratio of phage particles to bacterial cells (~1:100), but a much larger ratio of phage genomes to bacterial genomes (~4:1), implying that most gut phage are effectively temperate (e.g., integrated prophage, phage-plasmids, etc.). By integrating imaging and sequencing data with a generalized model of temperate phage dynamics, we estimate that phage induction and lysis occurs at a low average rate (~0.001-0.01 per bacterium per day), imposing only a modest fitness burden on their bacterial hosts. Consistent with these estimates, we find that the phage composition of a diverse synthetic community in gnotobiotic mice can be quantitatively predicted from bacterial abundances alone, while still exhibiting phage diversity comparable to native human microbiomes. These results provide a foundation for interpreting existing and future studies on links between the gut virome and human health.

Expanding the Controllable Range of the Mean Residence Time Ratio of Polydisperse Particles in Multiple-Chamber Fluidized Beds: A Coarse-Grained CFD-DEM Study

Expanding the Controllable Range of the Mean Residence Time Ratio of Polydisperse Particles in Multiple-Chamber Fluidized Beds: A Coarse-Grained CFD-DEM Study

Dielectric constant enhancement of BaTiO3/SU-8 for low-voltage droplet actuation

Digital microfluidics (DMF) technology, which called lab-on-a-chip will bring technological innovations to the field of biochemistry. Electro-wetting-on-dielectric (EWOD) is one of the forms of DMF which actuate independent droplets through electric field enabling more accurate and efficient actuation. Nowadays, the high driving voltage required for droplet actuation remains a major obstacle to the practical application of this technology. Dielectric layer is the main factor affecting the driving voltage. In this study, we fabricate a dielectric layer film that can reduce the driving voltage by doping BaTiO3 nanoparticles with high dielectric constant in SU-8 at room temperature. The volume ratio of dopant particles and spin coating speed are studied to determine the optimal processing conditions for low-voltage droplet actuation. As the volume ratio of the dopant particles increased, the dielectric layer dielectric constant firstly increases and then decreases. When the volume ratio of BaTiO3:SU-8 is 1:10, the maximum dielectric constant is achieved. The dielectric wetting properties follow the same trend as the change in dielectric layer dielectric constant. Thus, the parameters of a volume ratio of 1:10 and spin coating speed of 7500 rad/min are finally selected for the preparation of the dielectric layer. These measures resulted in lower threshold voltages for droplet actuation, which contributes to advancing the application and widespread adoption of DMF technology.

Experimental study and modeling of CaO carbonation: Effects of operating conditions on the carbonation behaviors of the calcined limestone particles

Thermochemical energy storage has received wide attention recently due to its high energy storage density and power cycle efficiency. However, most researchers focus on synthesizing new calcium-based heat storage materials, and there is still a significant knowledge gap on the effects of operating conditions on the carbonation behaviors of the calcium-based particles. In this study, the effects of carbonation temperature, CO2 concentration and raw particle size on the carbonation rate, conversion ratio and particle diameter were experimentally investigated. The results showed that the carbonation rate peaked between 873 K and 973 K, and it decreased at 1023 K due to sintering. Increasing the CO2 concentration from 15 vol% to 50 vol% enhanced the carbonation rate, while the promotional effect was weaker at higher CO2 concentrations. The maximum conversion ratio of the CaO particles was independent of the CO2 concentration, and the particle diameter increased by 7.3 % after the carbonation process. Additionally, a carbonation model was developed and validated by the experimental results. Simulation results revealed that increasing the raw particle size from 0.1 mm to 0.5 mm caused the carbonation reaction to transition from a kinetic-controlled regime to a diffusion controlled regime, significantly reducing the carbonation rate.

Modeling Particle Versus SEI Cracking in Lithium-Ion Battery Degradation: Why Calendar and Cycle Aging Cannot Simply be Added

Degradation models are important tools for understanding and mitigating lithium-ion battery aging, yet a universal model that can predict degradation under all operating conditions remains elusive. One challenge is the coupled influence of calendar and cycle aging phases on degradation mechanisms, such as solid electrolyte interphase (SEI) formation. In this work, we identify and systematically compare three different SEI interaction theories found in the literature, and apply them to experimental degradation data from a commercial lithium-ion cell. In a step-by-step process, and after careful data selection, we show that SEI delamination without any cracking of the active particles, and SEI microcracking, where cycling only affects SEI growth during the cycle itself, are both unlikely candidates. Instead, the results indicate that upon cycling, both the SEI and the active particle crack, and we provide a simple, 4-parameter equation that can predict the particle crack rate. Contrary to the widely-accepted Paris’ law, the particle crack rate decreases with increasing cycles, potentially due to changing intercalation dynamics resulting from the increasing surface-to-volume ratio of the active particles. The proposed model predicts SEI formation accurately at different storage conditions, while simply adding the degradation from pure calendar and cycle aging underestimates the total degradation.

Gravitational wave probe of Planck-scale physics after inflation

Particle decays are always accompanied by the emission of graviton quanta of gravity through bremsstrahlung processes. However, the corresponding branching ratio is suppressed by the square of the ratio of particle's mass to the Planck scale. The resulting present abundance of gravitational waves (GWs), composed of gravitons, is analogously suppressed. We show that superheavy particles, as heavy as the Planck scale, can be naturally produced during the post-inflationary reheating stage in the early Universe and their decays yield dramatic amounts of GWs over broad frequency range. GW observations could hence directly probe Planck-scale physics, notoriously challenging to explore.

Numerical prediction on frictional characteristics of binary mixtures consisting of flexible cylindrical particles and rigid spheres

A Discrete Element Method (DEM) model for deformable cylindrical particles is established to investigate the Jenike shear process of binary mixtures consisting of flexible cylindrical particles and rigid spheres. The effects of the shape of flexible cylindrical particles and the proportion of cylindrical particles to spherical ones on the friction behavior of the mixture are discussed. Numerical results show that both the shear stress and internal friction angle increase with the aspect ratio (Ar) of the flexible cylindrical particles but decrease with the increase of the proportion of spherical particles. The role of Ar becomes slight when when the amount of spheres are much higher than the cylindrical particles (double or higher). For the mono-system containing flexible cylindrical particles of Ar=6 but without spheres, the strong interlocking packing structure leads to high shear stress and internal friction angle. It is indicated that the inclusion of rigid spheres disrupts the interlocking structure between flexible cylindrical particles and acts as a lubricant during the shear process. Based on the numerical results, a predictive correlation is established to predict the frictional characteristics of binary mixtures consisting of flexible cylindrical particles and rigid spheres considering the effect of particle shape and proportion. Furthermore, through a microscopic analysis of the numerical results, a deeper understanding of this phenomenon is gained. It is confirmed that the spherical particles can fill the voids between the flexible cylindrical particles, increasing the compactness of the mixture and promoting lubrication effects. The current research contributes to the better understanding of the mechanism of particle flow and is of paramount importance to improve the kinetic theories for complex granular flows.

Effect of SiC dominated with ZrB2 particles on the ablation and mechanical properties of carbon/novolac‐epoxy (EPN1180) composite at 3000°C

AbstractThis study investigates the mechanical properties and erosion resistance of high temperature–pressure carbon‐epoxy novolac insulation reinforced with ZrB2/SiC particles. For this reason, at first, five samples were fabricated using the hot press, which included resin epoxy novolac EPN1180 base without reinforcement and four samples containing resin with 20:80, 30:70, 40:60, and 50:50 of SiC: ZrB2 particles respectively. After manufacturing of the samples, the mechanical properties were evaluated through bending and tensile testing, followed by erosion resistance properties by the use of oxyacetylene flame erosion tests. Chemical composition and surface morphology analysis of the composites were conducted using energy‐dispersive spectroscopy, scanning electron microscopy, and x‐ray diffraction analysis. Results indicate that the addition of ceramic particles enhances both mechanical properties and erosion resistance of the composite. The pure resin sample exhibited the highest weight loss and thickness reduction, while the sample containing 40% SiC and 60% ZrB2 demonstrated the least weight loss and thickness reduction about 55% and 83% respectively compared to pure sample. Additionally, the sample with 30% SiC and 70% ZrB2 had the lowest backside temperature. Furthermore, the sample with 20% SiC and 80% ZrB2 exhibited the highest mechanical properties, with a tensile strength of 422.5 MPa and flexural strength of 587.11 MPa. Morphological analysis revealed the presence of phases such as SiO2, ZrO2, and ZrSiO4 attributable to the ZrB2/SiC particles, contributing to the enhancement of erosion resistance.Highlights Examines volume ratios of ZrB2/SiC. Discovers the best particle ratio (20%SiC, 80%ZrB2) for mechanical properties. Identifies the best particle ratio (30% SiC, 70% ZrB2) for erosion resistance. Reveals key phases enhancing erosion resistance with advanced analysis methods. Linear and mass ablation rate improved by 83% and 55% (best formation).