We define a suitably tame class of singular symplectic curves in 4-manifolds, namely those whose singularities are modeled on complex curve singularities. We study the corresponding symplectic isotopy problem, with a focus on rational curves with irreducible singularities (rational cuspidal curves) in the complex projective plane. We prove that every such curve is isotopic to a complex curve in degrees up to five, and for curves with one singularity whose link is a torus knot. Classification results of symplectic isotopy classes rely on pseudo-holomorphic curves together with a symplectic version of birational geometry of log pairs and techniques from four-dimensional topology.