Catalytic regeneration has become one of the most promising technologies to solve the high energy consumption problem of CO2 capture in organic amine solutions. As the most mainstream type of catalyst, the instability of acidic catalysts in alkaline solutions attracts increasing attention from researchers. Herein, we proposed a composite catalyst of MnOOH loaded HZSM-5 to weaken the adsorption of alkaline substances and improve the catalytic stability of the catalytic material. The optimized catalytic effect is obtained when the mass ratio of MnOOH is 20% The CO2 desorption efficiency is increased by 68.2%, and the energy consumption is reduced by 31.8% when the dosage of the catalyst is only dosage of 0.2 wt% amine solution. Through materials characterization and DFT calculations, it was found that the surface O and hydroxyl groups on MnOOH are the key factors for proton cycling, and HZSM-5 has an important impact on improving proton transfer rate. This work provides a valuable approach to solving the stability problem of acidic catalysts.