Victims of sex trafficking and women purportedly involved in prostitution volun-tarily face a complex web of interconnected challenges when attempting to escape their current circumstances. By analyzing the shared and distinct challenges faced by these women, the paper aims to inform policymakers and service providers, offering recommendations to empower women seeking to escape exploitation through multi-disciplinary and interconnected networks of providers. This study surveyed 74 wom-en in Detroit, Michigan, using nonprobability convenience sampling over a 10-month period in 2020. It compared three groups of women who self-reported as victims of sex trafficking, women who voluntarily engaged in some form of commercial sex, and women currently not in the sex industry. The study examined five outcome dimen-sions: substance use, housing stability, violence, interactions with law enforcement, and healthcare barriers. Among surveyed women, 45 reported sex trafficking experi-ences, 20 engaged in prostitution voluntarily, and nine were currently neither traf-ficked nor in prostitution. While some experiences were shared, like drug use and child presence, unique challenges emerged for sex trafficking victims. Victims of sex traffick-ing reported higher rates of homelessness, violence, lower education, and poorer health compared to others. However, those who were trafficked and those who report-ed being voluntarily involved in the sex trade had many similar problems. The survey highlights the interconnected barriers faced by women in sex trafficking or prostitu-tion: substance abuse, homelessness, and health problems. All three groups of women reported having children, which underscores the great need for support systems for families of trafficking survivors or those in the sex industry. Educating professionals and raising awareness can enhance responses and interventions, enabling more women to design exit strategies and begin the path to recovery.