Rare Case Of Primary Tuberculosis Research Articles

Primary tuberculosis of the breast from mankweng hospital

Object of study: To share our experience with a rare case of Primary Tuberculosis of Breast.
 The problem to be solved: Tuberculosis of the breast is a rare type of extrapulmonary tuberculosis and usually affects young lactating multiparous women. It accounts for less than 0.1 % of all breast pathologies. Tuberculosis of the breast is often misdiagnosed. Therefore, a high index of suspicion is needed when evaluating cases of breast abscesses, fistulae, or mass.
 Main scientific results: A case of a 27-year-old female with no known co-morbidities, HIV negative who presented to our Surgical Outpatient Department with a 1-year history of a painless left breast lump. No previous history of pulmonary tuberculosis was reported. Breasts ultrasonography indicated BIRADS (Breast Imaging-Reporting and Data System) V: lesion highly suspicious of malignancy. Histopathological analysis of the core biopsy showed features of a necrotizing granulomatous mastitis with adjacent fat necrosis. Ziehl-Neelsen stain was negative though histological results were worrisome of a mycobacterial infection. Patient responded well to antitubercular therapy as evidenced by lump regression, ulceration healed, peau d’orage currently resolved, and the overall size of the breast is going back to its normal state.
 The area of practical use of research results: Family medicine physicians, Primary health care center, District level or regional level hospital.
 An innovative technological product: a high index of suspicion tuberculosis is needed when evaluating cases of breast abscesses, fistulae, or mass. Awareness of this condition is important as it can clinically, and radiologically mimic breast carcinoma.
 Scope of application of an innovative technological product: Family medicine physicians, Primary health care center.

‘TB or not TB’ – A rare case of primary tuberculosis of the breast

‘TB or not TB’ – A rare case of primary tuberculosis of the breast

A rare case of primary tuberculosis in a solitary thyroid nodule

Tuberculosis (TB) of the thyroid gland is extremely rare with fewer than 200 cases reported worldwide. We report a case of primary TB of the thyroid in a 73-year-old gentleman with no risk factors for TB, presenting with a painless right neck mass of one week's duration. A pre-operative ultrasound scan reported a solid-cystic, right TIRADS 5 nodule, and initial fine needle cytology showed granulomatous inflammation and was negative for AFB on Ziehl-Neelsen stain. A right hemithyroidectomy was done subsequently, and histology demonstrated necrotizing granulomatous inflammation, but TB-PCR detected Mycobacterium DNA.Primary TB of the thyroid is rare and can manifest in patients with no apparent risk factors for TB. Initial cytology may only yield granulomatous inflammation and surgery is needed to ascertain the exact cause of granulomatous inflammation and additional TB-PCR can help clinch the diagnosis.

A rare case of primary tuberculosis of the submandibular gland!!!

A rare case of primary tuberculosis of the submandibular gland is reported here which required surgical gland excision for definitive diagnosis. It is presented in view of its rarity, the extreme difficulty in the diagnosis of this kind of disease and highlighting the importance of histopathological examination.

A Rare Extra-Pulmonary Presentation Of Tuberculosis As Gum Tuberculosis

Tuberculosis (TB) is a chronic granulamatous disorder presenting mostly (80%) as a pulmonary disease, the extra-pulmonary presentation being relatively uncommon. The oral cavity can sometimes be a site for extra-pulmonary tuberculosis with a highly variable clinical presentation including ulceration, diffuse infl ammatory lesions, granulomas and fi ssures. Oral lesions usually appear secondary to a primary tubercular infection elsewhere, although primary infection of the oral mucosa by Mycobacterium tuberculosis has been described. We report here a rare case of primary tuberculosis of the hard palate extending to gingiva, manifesting as gingival enlargement with ulceration. Diagnosis was established by histopathological examination of tissue biopsy and by chest radiography. The patient was put on anti-tubercular therapy for nine months to which a prompt response was obtained. This emphasizes the need to consider tuberculosis in the differential diagnosis of non-healing mucosal lesions of oral cavity for early diagnosis and prompt treatment. SAARC Journal of Tuberculosis, Lung Diseases & HIV/AIDS; 2013; X(1); 37-39 DOI: http://dx.doi.org/10.3126/saarctb.v10i1.8675

Primary Lingual Tuberculosis in Immunocompetent Patient: a Case Report

Oral manifestations of tuberculosis are quite rare with an incidence rate of 1.4%. The tongue is the most common site of oral tuberculosis having varied presentations. Lingual tuberculosis is a diagnostic dilemma because of its rarity, particularly in immunocompetent patients. We are reporting a rare case of primary tuberculosis of the tongue in a 38 year old male diagnosed on fine needle aspiration cytology.

Primary Tuberculosis of the Tongue: A Case Report

The purpose of this article is to report a rare case of primary tuberculosis of the tongue. Tuberculosis is an infectious, chronic granulomatous disease that can involve almost any organ in the body, but primary lesions are usually confined to the lungs. Oral lesions are an infrequent occurrence in tuberculosis, and tuberculosis of the oral cavity is often a consequence of active pulmonary tuberculosis. Although primary tuberculosis in the oral cavity has been documented, it is a rare occurrence. A 42-year-old male patient presented with chief complaints of severe pain and ulceration on the ventrolateral surface of the left side of the tongue, measuring about 1.25 x 1.50 cm with surrounding erythema and induration of one-month duration. The ulcer was initially painless but became painful later with increased severity over time. The sore tongue caused difficulty in eating, drinking, swallowing, and even talking. The patient also complained of malaise for some duration, but there was no history of fever, cough, weight loss, and his bladder-bowel habits were normal. An excisional biopsy differentiated the lesion from squamous cell carcinoma and confirmed the diagnosis. Even though primary tuberculosis in the oral cavity is a rare finding, it must be included in the differential diagnosis of mucosal lesions. This case provides a clinical example of the importance of this inclusion for the well being of the patient and for the community due to the communicable nature of the disease.

Primary tuberculosis of bilateral submandibular salivary glands

A rare case of primary tuberculosis of bilateral submandibular salivary glands is presented with review of relevant literature. The patient was managed on conservative therapy.