Mechanoreceptors Research Articles

A Silver Nanowires‐Based Flexible Capacitive Touch Screen in Tactile Displays for Individuals with Visual Impairment Using Gesture Recognition

AbstractCapacitive touch screens (CTS's) are essential components in most of today's digital devices. However, for the visually impaired (VI) users due to the uneven topography of the tactile surface, CTS's are more challenging to implement and thus this field remains largely underdeveloped. Considering the limited space around the microactuators driving the typical Braille dots for a tactile screen with ten dots‐per‐inch (dpi) resolution, the materials used for CTS should be flexible and durable with high mechanical strength. In this work, a flexible CTS based on polyimide (PI) and silver nanowires (AgNWs) as electrodes with a total thickness of 210 µm is developed. The dimensions of the AgNWs are on average 7.9 ± 2.4 µm in length and 85 ± 24 nm in width. The AgNWs electrodes showed low resistance and good adhesion to the PI substrate. A gesture recognition application is collected from the capacitive data to classify different gestures (including single‐ and double‐click, swipe‐left and ‐right, scroll‐up and ‐down as well as zoom‐in and ‐out) with two different approaches; machine learning and deep learning are implemented. The best performance is obtained using the YOLO model with a high validation accuracy of 97.76%. Finally, a software application is developed with the proposed hand gestures in real‐time to foster interaction of VI users with the tactile display allowing them to navigate a Windows file system and interact with the documents via hand gestures in a similar manner as sighted users on a conventional touch display will be able to do. This work paves the way to utilize CTS for the tactile displays in the market developed for VI users.

Flexible Thermoelectric BiSbTe/Carbon Paper/BiSbTe Sandwiches for Bimode Temperature‐Pressure Sensors

AbstractBimode temperature‐pressure sensors hold significant promise in personal health monitoring, wearables and robotic signal detection. Traditional bimode sensors typically combine two independent sensors, leading to fabrication complexity. This study develops a bimode temperature‐pressure sensor by using a facile electrodeposition method to create sandwiched BiSbTe/Carbon Paper/BiSbTe thin films and stacking them to a vertical structure. It demonstrates high sensitivity for temperature sensing, capable of detecting temperature difference as low as 1 K, and a rapid response time of 0.92 s due to a vertical structure. Utilizing its thermoelectric mechanism, the sensor achieves self‐powered sensing for finger touch and respiration states. Furthermore, its island‐like contact surface ensures high sensitivity with an extremely fast response time of 0.17 s, by rapidly changing contact resistance under pressure, allowing it to detect various human behaviors, including body movements and micro‐expressions. Beyond its sensing capabilities, the film excels in flexibility, electromagnetic interference shielding, and stability, presenting significant potential for integration into self‐powered electronic skin systems for health monitoring, wearables, artificial intelligence, and other electronic skin applications.

Association of dietary choline intake with incidence of dementia, Alzheimer's disease and mild cognitive impairment: a large population-based prospective cohort study

ObjectiveExplore the associations between dietary choline intake and the incidence of dementia, Alzheimer's disease (AD), mild cognitive impairment (MCI), and current cognitive performance in the UK Biobank cohort. MethodsDietary choline intake was categorized into quartiles of consumption based on 24-hour dietary recalls, with units expressed as milligrams per day. Diagnoses of dementia, AD, and MCI were identified using ICD-9/10 codes. Current cognitive performance was assessed via the computerized touchscreen interface. After adjusting for sociodemographic factors, dietary and lifestyle behaviors, and comorbid conditions, Cox proportional hazards regression, logistic regression, and restricted cubic splines were used to analyze the association between choline intake and dementia or cognitive performance. ResultsAmong 125,594 participants (55.8% female), with a mean age of 56.1 years (range: 40 to 70 years) at baseline, and a median follow-up of 11.8 years, 1,103 cases of dementia (including 385 AD) and 87 cases of MCI were recorded. U-shaped associations were observed between choline intake and dementia and AD. Participants in the 2nd quartile of total choline intake had lower risks compared to those in the lowest quartile, with HR of 0.80 (95% CI: 0.67, 0.96) for dementia and 0.76 (0.58, 1.00) for AD. Moderate intake of choline derivative, including free choline (HR, 0.77; 95%CI, 0.65, 0.92), phosphatidylcholine (0.82; 0.68, 0.98), sphingomyelin (0.82; 0.69, 0.98) and glycerophosphocholine (0.83; 0.70, 1.00), were associated with a 17% to 23% lower odds of dementia. Additionally, moderate total choline intake was associated with an 8% to 13% lower odds of poor cognitive performance in visual attention (OR, 0.92; 95%CI, 0.86, 0.99), fluid intelligence (0.87; 0.82, 0.92), and complex processing speed (0.90; 0.84, 0.95). ConclusionsIn conclusion, our findings suggest that moderate dietary choline intake, ranging from 332.89 mg/d to 353.93 mg/d, is associated with lower odds of dementia and better cognitive performance.

Automation and innovation in home hemodialysis machines.

In this review, we discuss the timeline of innovation and technologic development in home hemodialysis (HHD) in the United States and the legislative approvals that accompanied them. The most recently FDA-approved home hemodialysis devices provide features that include on-demand and batch dialysate generation, access disconnect for venous needle dislodgement, touchscreen interface with visual and auditory prompts and animations, drop-in sterilized cartridges with prestrung tubing, hot water disinfection of tubing allowing extended-use, dialysate flow rates as high as 500 ml/min, as well as remote treatment monitoring capabilities. Furthermore, wearable/portable dialysis devices are currently under development to simplify dialysis delivery to patients with end-stage kidney disease. Home hemodialysis devices providing longitudinal hemodialysis across different clinical settings, virtual reality headsets for more personalized training, automated patient support, as well as wearable device development and innovations give hope for a future where home hemodialysis is more accessible and seamless.

Mobile crawler robot for seed sowing and route planning through neuro-diffuse control

The main objective of this project is to build a mobile terrestrial robot that allows the sowing of seeds of various types of plants that are cultivated in an artisanal way. A structure based on tracked locomotion has been designed that involves the use of several sensors, DC motors, and control systems based on two Arduino boards, which together allow the mobile robot to interact with the irregular environment through which it moves. The locomotion process carried out by the seeding robot is configured through an HMI interface implemented on a touch screen, where the user chooses the type and quantity of seeds to be sown so that the robot then follows an autonomous rectilinear trajectory which is supervised and corrected utilizing a neuro-diffuse control such as ANFIS. In addition, the mobile robot has a battery feeding and charging system through solar panels, which gives it complete autonomy to carry out the work entrusted to it.

Device to Measure, Monitor and Control Variables for Agricultural Purposes

The measurement of meteorological variables is important for decision-making in the field. Accurate data can help farmers optimize their activities to improve food production. Traditional methods of monitoring variables can be expensive or complex for small-scale farmers to use. This indicates a need for low-cost and user-friendly devices. Currently, there is technology for developing these types of devices, which could be useful to automate processes based on variable monitoring and improve food production. Due to this, a device based on the Arduino Mega<SUP>TM</SUP> board was developed to monitor air temperature, relative humidity, rain, and soil moisture. In addition, equipment was developed to be controlled based on a rain gauge. The device has a TFT touch screen for easy-user interaction and 4 menus for information display (summary, floor, date-time and manual equipment control). The program of the device required more lines of code (59.65%) to establish user-device interaction compared to its internal processes (18.66%) and variable declarations (21.68%). A container was 3D printed to house all the integrated circuits and the device was tested under both indoor (Jun-10, 2024 to July-17, 2024) and outdoor (Jul-22, 2024 to Aug-18, 2024) conditions. Under indoor conditions, a 3% difference was found in the temperature measurements taken under the same conditions (using DS18B20 and MLX90614 sensors). Under outdoor conditions it was found that the air temperature decreased by an average of 2.33°C when increasing the height from 8ft to 16ft and the relative humidity decreased by an average 3.48% when increasing the height from 8ft to 16ft. There was a 3.4% difference in total rain measured by the rain gauges. Finally, the developed device performed adequately during the two months of testing in both conditions, measuring variables and controlling equipment (the equipment went from waiting mode to rain harvesting mode 92 times).

One-Second Touchscreen Disinfection with Internal UVC-LEDs

The transmission of pathogens via touchscreens is a concern both in medical environments regarding nosocomial infections and in public spaces. This study presents the development of a self-disinfecting touchscreen system and its implementation into an existing medical device. The disinfection was achieved by irradiating UVC light laterally into the quartz front glass of the touchscreen. The system also included a two-stage safety shutdown feature to protect users from UVC exposure. To detect the presence of the user’s hand, a proximity sensor behind the front glass of the touch screen was installed in combination with touch input registration. A rapid disinfection of staphylococci was achieved without compromising usability and user safety. The prototype demonstrated a bacterial reduction of 99.96% or 3.4 (±0.36) log levels in less than 1 s. The results suggest that the technology has the potential to make a significant contribution to reducing the transmission of infections in healthcare settings and beyond.

Preparation and Characterization of Nanostructured ITO Thin Films by Spray Pyrolysis Technique: Dependence on Annealing Temperature

Transparent conducting oxides (TCOs) like Indium tin oxide (ITO) have wide attention from all scientists which have low resistance and high visible light transmittance, used as transparent electrodes in many optoelectronic devices such as liquid crystal displays, touch screens, light emitting diodes, and solar cells. In this research, the relationship between the crystallization, optical transmittance, and surface roughness of nanostructured ITO thin films and the change in annealing temperature was investigated. To enhance the efficiency of this material in optoelectronic applications, both the optical transmittance in the visible region and the crystallite size must be increased. These results can be obtained by the heat treatment of the films. Nanostructured ITO thin layer films have been successfully prepared at a substrate temperature equal to (350)℃ by chemical spray pyrolysis (CSP) technique. The physical characterizations of nanostructured ITO thin layer films were investigated at different annealing temperatures (400,450 and 500)℃. The presence of diffraction peaks indicates that the as-deposited and post annealed films are polycrystalline cubic structure and the peak (400) is a preferred growth orientation. For all samples the value of intensity of diffraction peaks increases with increasing substrate temperature. The crystallite size of nanostructured ITO thin films is strongly related to the annealing temperature. The crystallite size estimated from XRD was found to rise with rising annealing temperature. The surface roughness of nanostructured ITO thin layer films increases with rising annealing temperature. High values of transmittance have been measured in the visible region 550 nm equal to (70, 82, 84 and 88)% corresponding to annealing temperature (350,400,450 and 500)℃ respectively.

Hierarchically‐Interlocked, Three‐Axis soft Iontronic Sensor for Omnidirectional Shear and Normal Forces

AbstractArtificial tactile sensing capable of measuring shear and normal forces is crucial for the diverse human‐machine interactions and dexterous robotic manipulations. However, existing soft multi‐axis force sensors usually suffer from limited detectable directions and complex coupling mechanisms, limiting their applications in realistic wearable and robotic systems. Here, a hierarchically‐interlocked, three‐axis soft iontronic sensor is presented with an asymmetrical electrode pattern that leverages the mortise‐and‐tenon structure and ultracapacitive principle to detect omnidirectional shear and normal forces. The designed sensor facilitates the decoupling process and achieves enhanced sensing performances including high accuracy, fast response ability, and mechanical robustness. Prototypical integration and application of the sensor are demonstrated to perform wearable telecontrol of virtual platforms and assist robot gripper through closed‐loop force feedback. A sensing array is further developed to construct a touch panel and identify handwriting based on the continuously measured directions of applied forces. This work may offer a potentially promising solution for the next‐generation intelligent electronic skins requiring multimodal tactile sensing information.

Wind power plant site selection problem solution using GIS and resource assessment and analysis of wind energy potential by estimating Weibull distribution function for sustainable energy production: The case of Bitlis/Turkey

Wind energy, being a sustainable energy source, is a benign, dependable, limitless, and cost-effective source of energy. This study involved the creation of a wind power plant site selection map at a provincial scale using a GIS application. The map took into account both environmental risks and environmental criteria. A wind energy measurement station of the PCE-FWS 20 type, equipped with a touch screen, was installed in the Rahva campus of Bitlis Eren University. Over the course of one year, data on wind direction, wind speed, temperature, relative humidity, and air pressure were collected at 5-s intervals and averaged over 20-min periods. The purpose of this study was to assess the suitability of the measured region for wind energy potential. A comprehensive statistical analysis was conducted using all the data collected during this period to assess the wind energy potential in the studied region. The Weibull distribution was employed to analyse the wind energy potential of this particular region. We employed graphical techniques to ascertain the Weibull distribution. The wind data analysis and simulation were conducted using the Matlab application. Analysed were the monthly statistical wind energy potential of the region, wherein the average wind speed and power density values were determined and presented through graphs at 20-min intervals. Upon analyzing the map generated using the Geographical Information Systems (GIS) technique, it has been ascertained that Bitlis Eren University Rahva campus is located in favorable areas.

Dual‐active‐layer flexible piezoresistive sensor based on wrinkled microstructures and electrospun fiber network for human‐related motion sensing applications

AbstractFlexible pressure sensors with high sensitivity and a wide detection range must be developed for practical applications. In this study, a dual‐active‐layer flexible piezoresistive sensor was developed. A reduced graphene oxide film with wrinkled microstructures was prepared by a simple and low‐cost substrate pre‐stretching method and used as the first active layer. A thermoplastic polyurethane electrospun fiber membrane was modified by fast polydopamine coating and ultrasonication with multi‐walled carbon nanotubes and used as the second active layer. Owing to the continuously changing conductive pathways created by the wrinkled microstructures and fiber network under pressure deformation, the sensor achieved a detection range of 0–100 kPa, with sensitivities of 8.5, 1.35, and 0.39 kPa−1 in the ranges of 0–1, 1–20, and 20–100 kPa, respectively. Additionally, the sensor exhibited a low detection limit (2 Pa), response and recovery times of 105 and 85 ms, respectively, and reliable service performance over 10,000 loading/unloading cycles. The sensor enabled real‐time monitoring of finger and wrist bending, beaker‐holding, and fingertip‐sliding on a touch screen, demonstrating its feasible applications in wearable electronics and human–machine interface devices.

In-situ cured gel polymer/ecoflex hierarchical structure-based stretchable and robust TENG for intelligent touch perception and biometric recognition

Gel-based sensors for next generation touch panels have been acknowledged for their exceptional sensitivity and flexibility. However, these sensors typically depend on a metal grid connection, which is susceptible to structural deformation under heavy stress applications and necessitates external power. Here, we report a novel in-situ cured gel polymer electrode-based triboelectric nanogenerator (GPE-TENG) that is stretchable, semi-transparent, and durable, designed to enable a self-powered touch panel for intelligent touch perception. The in-situ curing of the hierarchical structure of the ionic polymer gel encapsulated within the ecoflex ensures robust adhesion of the ionic conductive polymer gel (PEO/LiTFSI) to the ecoflex layers, addressing the issue of delamination in TENG components under mechanical stress. As a result, the GPE-TENG demonstrates high durability, enduring under stretching of approximately 375 % and sustaining heavy mechanical deformations (under folding, twisting, and rolling) over a long period (approximately 2 months) without loss of functionality. Remarkably, the GPE-TENG exhibits outstanding energy harvesting capabilities with a peak power density of 0.36 W m-2. Notably, the GPE-TENG generates electrical signals through simple device stretching, thus serving as a self-powered wearable sensor for human activity monitoring. Moreover, a 9-digital arrayed (3 × 3) flexible, semi-transparent, and self-powered touch panel based on the GPE-TENG shows multifunctionality, including touch track/pattern recognition (i.e. touch and sliding mode) and a highly accurate (∼98 %) deep learning assisted smart biometric system for user identification.

A Signal Amplitude-Insensitive Triboelectric Touch Panel with a Significantly Reduced Signal Channel and Deep-Learning-Enhanced Robustness.

The self-powered triboelectric touch panel has garnered considerable research attention due to its potential to reduce system energy consumption and its applications in human-machine interfaces, e-skin, and the Internet of Things. Current methods for achieving triboelectric-based touch positioning in an M × N detection pixel array typically require signal amplitude comparison across at least M + N signal channels, thereby limiting lightweight design possibilities. In contrast, our novel "resistor ladder" approach necessitates only 4 signal channels for touch positioning. This method leverages a lookup table correlating touch positions with amplitude ratios from different channels, rendering it insensitive to signal amplitude and significantly enhancing robustness. We fabricated a transparent touch panel using PET tribomaterial, where the surface roughness was enhanced through plasma treatment. The panel successfully demonstrated touch positioning for 128 taps within a 4 × 4 pixel detection array and sliding positioning using a predefined lookup table. To further enhance device robustness, a 2D convolutional neural network was implemented, which achieved an impressive touch positioning accuracy of 97.7% even under artificially introduced signal defects. This study represents an initial exploration of amplitude-insensitive touch and sliding positioning methods, significantly reducing the number of required signal channels and enhancing the robustness of triboelectric touch panels.

Bulbul Memorial Museum as a Center of Cultural and Historical Memory

The aim of the article is to study and introduce into scientific circulation information about the current activities of the Bulbul Memorial Museum regarding the preservation of the musical heritage of the founder of the professional vocal art of Azerbaijan. The material base of the study consists of the exposition of the Bulbul Memorial Museum and archival sources. Results. The article examines the history of creation and the current activities of the Bulbul Memorial Museum in Shusha after the occupation. The exposition of the museum is characterised, which presents Bulbul’s personal belongings, materials reflecting his creative, scientific, educational and social activities. The article provides a brief overview of the artist’s creative achievements, and also examines Bulbul’s documents and works. In particular, the article begins a discussion about such a peak of Bulbul’s work as the opera “Keroglu”. The activities of the Research Music Cabinet, which plays an indispensable role in the history of the musical culture of Azerbaijan, are highlighted. Information is provided on the unique exhibits known as phonograph records, which are well preserved at the Bulbul Memorial Museum. Scientific novelty. For the first time, the role of information technologies in the presentation of the Bulbul Memorial Museum is studied through the prism of preserving the musical heritage of the founder of professional vocal art of Azerbaijan. Conclusions. The Bulbul Memorial Museum in Shusha contains a powerful display of personal things and documents highlighting Bulbul’s musical legacy as the founder of professional vocal art in Azerbaijan. The use of information technologies for the presentation of the museum’s exposition meets modern requirements of museum activity. The use of a modern technological tool in the Bulbul house-museum — a monitor with a touch screen — is an important feature that arouses interest in the museum.

Deciphering the genetic basis of behavioral traits in dogs: Observed-trait GWAS and latent-trait GWAS analysis reveal key genes and variants

Dogs exhibit remarkable phenotypic diversity, particularly in behavioral traits, making them an excellent model for studying the genetic basis of complex behaviors. Behavioral traits such as aggression and fear are highly heritable among different dog breeds, but their genetic basis is largely unknown. We used the genome-wide association study (GWAS) to identify candidate genes associated with nine behavioral traits including; stranger-directed aggression (SDA), owner-directed aggression (ODA), dog-directed aggression (DDA), stranger-directed fear (SDF), nonsocial fear (NF), dog-directed fear (DDF), touch sensitivity (TS), separation-related behavior (SRB) and attachment attention-seeking (AAS). The observed behavioral traits were collected from 38,714 to 40,460 individuals across 108 modern dog breeds. We performed a GWAS based on a latent trait extracted using the confirmatory factor analysis (CFA) method with nine observable behavioral traits and compared the results with those from the GWAS of the observed traits. Using both observed-trait and latent-trait GWAS, we identified 41 significant SNPs that were common between both GWAS methods, of which 26 were pleiotropic, as well as 10 SNPs unique to the latent-trait GWAS, and 5 SNPs unique to the observed-trait GWAS discovered. These SNPs were associated with 21 genes in latent-trait GWAS and 22 genes in the observed-trait GWAS, with 19 genes shared by both. According to previous studies, some of the genes from this study have been reported to be related to behavioral and neurological functions in dogs. In the human population, these identified genes play a role in either the formation of the nervous system or are linked to various mental health conditions. Taken together, our findings suggest that latent-trait GWAS for behavioral traits in dogs identifies significant latent genes that are neurologically prioritized.

A COMPREHENSIVE REVIEW ON GRAPHENE: HISTORICAL DEVELOPMENT, PROPERTIES, APPLICATIONS, CHALLENGES AND FUTURE SCOPE

Graphene, due to its extraordinary properties is revolutionizing various fields. This paper explores some unusual characteristics of graphene such as mechanical properties, electrical and thermal conductance, and optical transparency. We will discuss its potential uses in various areas: super-strong composites for ultra-light and extra-durable materials and next-generation gadgets where graphene exposure might offer improved speeds. In addition, the possible applications of this nano-material in developing novel clear and flexible touch panels and advanced water filtration technologies are explored. But there are also problems with increasing output, maintaining the quality, and managing safety and health aspects despite its great potential. The paper also discusses the probable future impact of graphene on the sector of medicine, the usage of renewable energy, smart communities, and more. This analysis enhances the identification of graphene as a future wonder material by highlighting the state of research, the application of the material, and the opportunities as well as the challenges that the field has and will encounter.

棉花精量铺膜穴播机自动断膜带系统设计与试验

To achieve the process of automatic film cutting for cotton and improve the efficiency of cotton precision film hole seeding machine operation, this paper proposes a wireless handle button control method and designs a automatic film and tape cutting system for cotton precision film-laying hole seeder. The system includes electromagnetic integrated valve group, hole opener lifting hydraulic cylinder, membrane pressing hydraulic cylinder, multifunctional hydraulic cylinder for cutting film, strapping support hydraulic cylinder, hydraulic limit sensor, arc-shaped film cutting shovel reset sensor, wireless control handle for film cutting and film cutting controller. The system is based on the VisualTFT platform, equipped with a multi-functional touch screen. By integrating functions such as obtaining the forward distance of the machine, hydraulic control principles, and wireless control models for film cutting and burying, it achieves automatic cutting and burying of ground film and drip tape processes. The experiment verified the working performance of the automatic film cutting and feeding system of the cotton seed precision film mulching hole seeder and the results showed that the average monitoring accuracy of the machine's forward distance was 98.16%; the response time for controlling the film cutting belt and burying film belt was ≤0.78s, and the execution time was ≤2.68s; the success rate of cutting film strips was 100.00% and the success rate of burying film strips was above 98.33%, which met the operational requirements of automatic film strip cutting for precise cotton seeding film hole planting machines.

Assessing the stability of responding of male mice in the touchscreen 5 choice serial reaction time task: Focus on premature responding.

The five-choice serial reaction time task (5CSRTT) is a test of attention that provides a well-validated ancillary measure of impulsive action, measured by premature responses. The task has been adapted for mice in touchscreen operant boxes, which is thought to offer improved test-retest reliability. Few studies have assessed the long-term stability of performance, including premature responding in this version of the task. We used the touchscreen 5CSRTT to conduct longitudinal testing of stability of premature responding following repeated behavioral and pharmacological manipulations. Male C57BL/6J mice were trained on a baseline version of the 5CSRTT. They were then tested on versions of the task in which the stimulus duration was reduced, and inter-trial intervals were elongated or varied within-session. Premature responding was subsequently tested following administration of pharmacological agents known to bi-directionally affect attention and impulsive action-cocaine, atomoxetine, and yohimbine. Mice were lastly re-tested 6 months later using the 5CSRTT with elongated inter-trial intervals. A reduced stimulus duration impacted attention, with reduced accuracy and increased omissions, but had no effect on premature responding. Both elongating and varying the inter-trial interval within-session increased premature responses. Mice showed similar and stable levels of increased premature responding 6 months later. Cocaine increased premature responding, though less than previously reported in rats. Atomoxetine reduced premature responding. Yohimbine had no effect on premature responding in the baseline task but decreased premature responding when tested using an elongated inter-trial interval. Overall, these results highlight that the touch screen adaptation of the 5CSRTT is an effective method for longitudinal testing of attention and impulsive action and remains sensitive to performance changes arising from repeated pharmacological and behavioral challenges.

Abstract B142: The impact of financial toxicity as a barrier to access and participation in early phase clinical trials for underrepresented populations using the COST–FACIT tool

Abstract Background: ASCO has reaffirmed critical role of early phase (EP) clinical trials (CT) in cancer research and treatment that patients (pts) may achieve improvement in quality of life, experience psychological and direct medical benefits. Disparities in access and participation to CT exist and are more profoundly seen in EP CT with challenge of engaging underrepresented populations (UP) in EP CT which are often complex and only available at larger cancer centers in metropolitan areas. NCI’s Create Access to Targeted Cancer Therapy for Underserved Populations (CATCH-UP.2020) helped bring EP CT to UP. To determine the impact of financial toxicity (FT) as a barrier specific to EP CT participation of UP, the validated COST-FACIT tool was used to survey cancer pts undergoing treatment at the University of Kansas Cancer Center. Methods: This study was approved by our Institutional Review Board (Study 00150640). During routine scheduled visits, pts completed COST-FACIT survey on touch screen tablet. A list of validated questions on EP CT awareness, access, and willingness to participate were included in the survey. Pts responded to 12-item COST-FACIT questionnaire describing the relationship between financial stress and treatments (scale 0 to 4). The score was computed using responses captured from COST-FACIT. Based on literature, scores <26 were determined to be higher FT. Two-sided Fisher's Exact Tests were used to test for a significant association at an alpha level of 0.05. UP included racial and ethnic minorities, low socioeconomic status, low education, and rural. Results: Of 108 pts, 101 completed surveys. 45% identified as female and 55% as male. 11.2% 18–35 years (yrs) of age, 13.9% 36 –50 yrs, 24% 51–65 yrs and 54% >65 yrs. 62.4% were white, 17.8% black, and 19.8% others (Asian or Native American). 8.9% completed <12th grade, 23.8% completed high school, 29.7% have some college experience, 22% completed college and 16% have master’s/doctoral degree. COST-FACIT mean score was 25.7 (SD 10.4, r^2 of 0.48) showing significant financial stress. 46% of pts had scores <26. Pts 18-35 yrs (p=0.02), 36–65 yrs (p=0.00), had yearly incomes of >150,000 (p=0.02) or unaware of their yearly income (p=0.05) were more likely to have significant FT. Pts with < 12th grade (14.89%) or some college experiences (34.09%) were likely to have significant FT. Pts identifying as Asian or Native American were more likely to experience FT than white or black. Conclusion: Almost half of our pts suffer from significant FT creating disparities in EP CT access and participation. Data suggest ages 35-65 yrs, low levels of education, and races other than white and black experience higher levels of FT that is a barrier to EP CT participation. These data support our ongoing efforts to bring innovative EP CT to everyone including the VA and our other outreach partners with higher concentrations of UP. Data on rural and health professional shortage areas will be reported during the meeting. This project was supported in part by The University of Kansas Cancer Center P30CA168524. Citation Format: Kamiyah Hicks, Anusha Chidharla, Dinesh Pal Mudaranthakam, Hope Krebil, Issa Espinoza, Asuka Suzuki, Sam Pepper, Angelica Allen, Jill Hamilton - Reeves, Debra Sullivan, Anna Arthur, Saqib Abbasi, Anup Kasi, Rahul Parikh, Elizabeth Wulff - Burchfield, Al - Ola Abdallah, Lori Barbosa, Erin Carroll, Jennifer Heins, Tara Lin, Gary Doolittle, Weijing Sun, Joaquina Baranda. The impact of financial toxicity as a barrier to access and participation in early phase clinical trials for underrepresented populations using the COST–FACIT tool [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr B142.

Human body features recognition based adaptive user interface for extra-large touch screens

With the widespread use of extra-large touch screens (eLTS) in various settings such as work and education, interaction efficiency and user experience have garnered increased attention. The current user interface (UI) layouts of eLTS are primarily categorized into two modes: fixed position and manual adjustment. The fixed UI layout fails to accommodate users of different heights and sizes, while the manual adjustment mode involves cumbersome steps and lacks sufficient flexibility. This study proposes an adaptive UI for eLTS. The optimal operational area on the eLTS is determined based on users’ height, eye level, arm length, face orientation, and distance from the screen. The eLTS menu is then positioned and displayed within this optimal area. Simulations involving users of various heights (P1 female, P50 male and female, and P99 male) were conducted to evaluate fatigue using the rapid upper limb assessment (RULA) method. The results indicate that the proposed adaptive UI significantly reduces user fatigue.