To investigate anovel in-office three-dimensionally (3D) printed polymer bracket regarding slot precision and torque transmission. Based on a0.022″ bracket system, stereolithography was used to manufacture brackets (N = 30) from ahigh-performance polymer that met Medical Device Regulation(MDR) IIa requirements. Conventional metal and ceramic brackets were used for comparison. Slot precision was determined using calibrated plug gages. Torque transmission was measured after artificial aging. Palatal and vestibular crown torques were measured from 0to 20° using titanium-molybdenum(T) and stainless steel(S) wires (0.019″ × 0.025″) in abiomechanical experimental setup. The Kruskal-Wallis test with posthoc test (Dunn-Bonferroni) was used for statistical analyses (significance level p < 0.05). The slot sizes of all three bracket groups were within the tolerance range according to DIN13996 (ceramic[C]: 0.581 ± 0.003 mm; metal[M]: 0.6 ± 0.005 mm; polymer[P]: 0.581 ± 0.010 mm). The maximum torque values of all bracket-arch combinations were above the clinically relevant range of 5-20 Nmm (PS: 30 ± 8.6 Nmm; PT: 27.8 ± 14.2 Nmm; CS: 24 ± 5.6 Nmm; CT: 19.9 ± 3.8 Nmm; MS: 21.4 ± 6.7 Nmm; MT: 16.7 ± 4.6 Nmm). The novel, in-office manufactured polymer bracket showed comparable results to established bracket materials regarding slot precision and torque transmission. Given its high individualization possibilities as well as enabling an entire in-house supply chain, the novel polymer brackets bear high potential of future usage for orthodontic appliances.