Ramifications For Individuals Research Articles

“Should We Stay or Should We Go now?”

In this paper we focus on a special feature of science and technology studies: the trajectories of our engagement with ‘emerging technosciences’. Many of us entertain close links to a particular group of scientists; our scholarly careers and identities build around thematic specialisations, trans-field collaborations and convivialities. But more often than not, such engagement does not last a whole career. With every new technoscientific hype, scholars are pressed to ‘move on’, to disengage from one field and re-engage with another. It thus seems warranted to explicitly reflect on the temporal patterns of dis/engagement and to look at possible ramifications for individuals, collectives, and the innovation system at large. To inform such reflection, we opted for a mixed-methods approach, tracing patterns and moments of dis/engagement across various disciplines based on scientometric analysis, individual archaeologies of engagement, a qualitative survey, and a focused discussion among fellow scholars from the social sciences and humanities as well as the sciences. Our analysis brings distinct dis/engagement patterns to the fore, relating to disciplinary affiliations as well as career stages. In our conclusion, we discuss the relevance of these findings for science and technology studies scholars and technoscientists as well as for contemporary innovation regimes more generally.

International perspective on healthcare provider gender bias in musculoskeletal pain management: a scoping review protocol

IntroductionChronic pain affects millions of individuals worldwide. Healthcare provider gender bias in the management of these individuals has societal and individual ramifications. Yet, a thorough and comprehensive literature summary on...

‘The earrings:’ friendship across ethnic and gendered boundaries in the American West

ABSTRACTHow were relationships negotiated across ethnic, racial, and gendered boundaries in the American West in the 1920s and 1930s? Were friendships possible? What limits shaped them? In 1927, four Kiowa students enrolled at Oklahoma University as students of Swedish-born Professor of Fine Arts Oscar B. Jacobson. This article investigates the relationship between Jeanette Berry, wife of one of the Kiowa artists, and Sophie Brousse, Jacobson’s French wife. It focuses on an incident when Berry presented Brousse with a gift of earrings. Placing this gift within a discussion of friendships between strangers illuminates the lines of culture, meaning, and power that separated these women. This relationship had individual ramifications but also formed part of their respective attempts to establish positions and maintain culture within Oklahoma where both American Indians and immigrants faced changing and volatile conditions. Their encounter highlights issues of class as well as ethnicity and culture.

"Women’s Ascents to Executive Leadership: Expanding, Prospecting and Moving as Strategy"

While much research has identified the myriad reasons why women are not reaching leadership roles in the highest echelons of organizations, there is a paucity of research that explains how some women do. This dissertation explores how women in the Middle East and North Africa reach executive corporate leadership. I identify three navigational behaviors (expanding, prospecting, moving) and show how women use these behaviors to move across structures and settings. Contributions to the theory and ramifications for individuals and organizations are discussed.

Entrenched gendered pathways in science, technology, engineering and mathematics: Engaging girls through collaborative career development

Gendered educational and occupational pathways are entrenched in many countries. The underrepresentation of women in the science, technology, engineering and mathematics (STEM) fields has ramifications for individuals and for workforces. Girls’ declining interest in STEM coincides with an increasing demand for STEM-skilled professionals across the globe. This conceptual analysis establishes the extent of STEM gender inequality in Australia and argues that the lack of women in these fields is problematic. Research using Eccles’ expectancy-value theory explains gender differences in mathematics and science expectations and values. Implications for career advisers are outlined including: recommendations for engaging girls in STEM while they are in primary school; collaborating with teachers; using role models and mentors; working with families to promote STEM; and focussing on specific groups of girls. The aim of this analysis is to assist career advisers to explore STEM educational and occupational pathways with girls.

Achieving Public Health Goals Through Medicaid Expansion: Opportunities in Criminal Justice, Homelessness, and Behavioral Health With the Patient Protection and Affordable Care Act

States are currently discussing how (or whether) to implement the Medicaid expansion to nondisabled adults earning less than 133% of the federal poverty level, a key aspect of the Patient Protection and Affordable Care Act. Those experiencing homelessness and those involved with the criminal justice system--particularly when they struggle with behavioral health diagnoses--are subpopulations that are currently uninsured at high rates and have significant health care needs but will become Medicaid eligible starting in 2014. We outline the connection between these groups, assert outcomes possible from greater collaboration between multiple systems, provide a summary of Medicaid eligibility and its ramifications for individuals in the criminal justice system, and explore opportunities to improve overall public health through Medicaid outreach, enrollment, and engagement in needed health care.

Abstract 5356: Brca1 Is An Essential Regulator Of Cardiac Function

INTRODUCTION: Preservation of structure and function of the myocardium is critically dependent upon improving the survival of existing cardiomyocytes (CM), through strategies that limit CM apoptosis and DNA damage. BRCA1 is a tumor suppressor gene which functions to promote DNA repair, and protect cells against oxidative and genotoxic stress. We hypothesized that BRCA1 is a novel cellular target to limit CM apoptosis, and prevent aberrant cardiac remodeling. METHODS AND RESULTS: Experimental MI in mice caused a profound 16-fold upregulation in BRCA1 expression, which peaked at 72 hours (p<0.01). In vitro gain-of-function experiments demonstrated that Ad-BRCA1 overexpression protected neonatal rat CM against doxorubicin- and H 2 O 2 -induced apoptosis, as assessed by FACS (p<0.01) and activated caspase-3. Ad-BRCA1-expressing CM exhibited a profound reduction in p53 expression in response to doxorubicin and H 2 O 2 . Co-immunoprecipitation studies demonstrated a distinct physical interaction of BRCA1 with p53. Inhibition of p53, with pifithrin-alpha, blocked doxorubicin-induced CM apoptosis in a manner similar to BRCA1, but BRCA1-overexpressing CM, when treated with doxorubicin did not show further reduction with pifithrin-alpha, indicating an essential requirement of BRCA1 to modulate p53. In vivo gain-of-function studies demonstrated that systemic Ad-BRCA1 delivery completely prevented doxorubicin-induced cardiac dysfunction in mice (echocardiography, p<0.01). In vivo loss-of-function studies were performed in CM -specific BRCA1-KO mice (developed using Cre-lox P technology), which demonstrated marked cardiac dysfunction and mortality in response to doxorubicin administration (p< 0.01 vs. WT + Dox). CONCLUSIONS: We report for the first time an essential role of BRCA1 to limit CM apoptosis, and improve cardiac function in response to genotoxic and oxidative stress. Heart specific deletion of BRCA1 promotes severe systolic dysfunction, and limits survival. In addition to the immediate implications for cardiovascular repair, these data may have ramifications for individuals with BRCA1 mutations or cancer syndromes, particularly in the setting of adjuvant chemotherapy.

A history of sex and the state in Southeast Asia: class, intimacy and invisibility

This essay offers a history of international marriages that questions the definition of marriage and what it meant to belong, as a legal subject or citizen, to a colonial state in Southeast Asia. European imperial states deployed monogamous marriage alongside other weapons of empire as a justification for intervention into Southeast Asian societies. With monogamous marriage came also European notions of belonging that traced surnames and legal subject status (later citizenship) via husbands and fathers. The ramifications for individuals in international marriages between Asian women and European men are well known. However, the vast majority of ‘international marriages’ were not those between colonial Europeans and Southeast Asian women, but between Southeast Asian women and lower class Asian men from India and China. Colonial states ignored or failed to register these lower class intra-Asian intimacies because their unions did not threaten colonial rule so long as they ensured a continuous pool of labor and promoted the colonial economy. Unlike recent theories which argue for an omniscient state that penetrates into the personal lives of its populations, this essay maintains that states intensely regulated marriage and belonging for some subjects but not for others. This longstanding unevenness in the management of intimate unions provides a historical context for understanding shifts in the marital regimes of contemporary postcolonial states. Taking a long-term view, the essay asks if recent increases in international marriages might be better understood as spikes rather than as absolute increases resulting from ‘globalization’. A historical framework ties the rise and fall of international marriage to early modern trade patterns, imperialism's labor requirements, war, and the recent demand for labor that has arisen from low birth rates and economic changes. Each of these ‘events’ entailed a large-scale movement of populations which resulted in the development of intimate unions.

Soul Healing and the Family

SUMMARY This article focuses on families in general, both those we as social workers and other mental health professionals work with and those within which we live. Specifically, the focus is on ways that growth may be facilitated as family members operate according to the principles of acknowledging connectedness, suspending judgment, trusting the universe, creating realities, and walking the path with heart. The ramifications for individuals, families and society of the choice to pursue soul healing, or to undertake consciously a journey toward wholeness, also is discussed.

The Moderating Effects of Gender and Race in Predicting the Academic Performance of College Developmental Students

The selection of students who are most likely to succeed in a college developmental studies program is a task with serious ramifications for individuals and institutions. The present study examined the moderating influence of gender and race on the accuracy of high school grades and College Board Scholastic Aptitude (SAT) scores in predicting the academic performance of developmental students. The results indicated significant slope differences in the regression lines for race with the equation for blacks accounting for 10 percent more variance than the equation for whites. Within the racial groups, significant intercept differences based on gender were found for whites only. The relationship between high school grade point average and SAT scores in predicting freshman grade point average for developmental students was similar to the relationship reported for regularly admitted students.