Because of the increased use of ionizing radiation, radiation management and security procedures are now regarded a standard part of many therapeutic and specialist fields. The focus of this work is on the radiation security features of Novel Oxide Glass (PZBKTANEr). The unique glass assembly is 40P2O5-30ZnO- 20BaF2-3.8K2TeO3- 1.2Al2O3-5Nb2O5-3Er2O3 in mol percent (test code PZBKTANEr). For the suggested oxide glass, several radiation shielding characteristics have been investigated for a specific energy range of ionizing radiation. The linear and mass attenuation coefficients, mean free path, half-value layer, total nuclear and electronic cross-sections, and fast neutron expulsion cross-section are among the radiation shielding properties. Furthermore, the unique fabricated glass (PZBKTANEr) was compared to commonly used radiation protection compositions, such as RS-253 G18, RS-360, RS-520, Chromite, Ferrite, Magnetite, and Barite glass, as well as RS-253 G18, RS-360, RS-520, Chromite, Ferrite, Magnetite, and Barite glass. Also, we studied the structure of fabrication by using Raman spectra. The findings suggest that the new oxide glass might be used in a broad variety of ionizing radiation applications for protection in both therapeutic and industrial applications.