Radiation materials pose a serious danger to human life and health, especially for personnel who interact with such materials in the performance of their duties. The effect on the human body of ionizing radiation that emits radiation material manifests itself in the form of «radiation sickness», when all human organs are affected, and radioactive rays can cause gene mutations that can be inherited in the form of deformities or serious diseases. For this reason, it is very important to ask whether the radiation safety of officials of customs authorities is ensured at a sufficient level, who, when carrying out customs control of such materials, endanger their lives and health. The analysis carried out in the study testifies to the disparity in the requirements and established rules for ensuring the safety and protection of the health of customs officials working with radioactive materials. In this regard, this article studied the risks of the negative impact of radiation materials on the health of a customs inspector during customs control, studied in detail the process of organizing the work of group «A» personnel who have access to work with such materials, and formulated appropriate conclusions and recommendations for eliminating imperfections in ensuring the radiation safety of customs officials from the harmful effects of radioactive materials in order to protect the life and health of the inspector from the radiation threat in the performance of his duties.