One of the important areas of humanitarian research in the first quarter of the 21st century was the problems of transhumanism, including the analysis of its cultural aspects. The aim of this study is to characterize the specific features of transhumanist culture in relation to the issue of subjectivity concerning the posthuman. The research was based on a number of methods, including: analysis and synthesis, deduction and induction, generalization, as well as philosophical-historical and hermeneutic methods. It is emphasized that the corporeality of human beings, serving as a crucial factor in the formation of culture, significantly determines the properties of subjectivity. A culture devoid of human subjectivity degenerates into a lifeless body of civilization. However, certain strands of posthumanism aim for a radical transformation of the body, potentially leading to its elimination through NBICS technologies (Nanotechnology, Biotechnology, Information technology, Cognitive science, and Socio-Humanities). To understand the projects of immortalism, the concepts of “subject-for-itself” and “subject-for-us” are introduced. Based on the results obtained, conclusions are drawn indicating that technological determinism, as a methodological approach to the investigation of posthuman issues in transhumanism, has been absolutized. As a result, this can lead to the desubjection of the posthuman and the elimination of the culture of posthumanism as a whole.
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