This paper presents our experimental work to assess the capability of estimating the transient-induced power distribution evolution in the CABRI experimental reactor, using Cherenkov radiation in optical fibers. The CABRI reactor is designed to produce power transients from 100 kW up to 21 GW in less than 100 ms, in order to irradiate a test fuel pin under conditions representative of a Reactivity Insertion Accident in pressurized water reactors. Because of the wide response range and short response time required to follow the reactor power evolution during a complete transient, the usual means of detection, such as ionization or fission chamber, are rendered inoperable, especially for in-core or core vicinity measurements. For this reason, we suggest measuring the Cherenkov light produced within the optical fibers. The Cherenkov light emission is linked to local electron production, which is proportional to local gamma flux through the Compton or pair production cross-section. In other words, the intensity of Cherenkov radiation is related to the photon flux intensity. Knowledge of the fission photons emitted by the reactor gives direct insight into the fission rate, hence a spatial power density distribution could be reconstructed by using the measurement of Cherenkov light at different points in the reactor. The radio-luminescence measurements taken using photodiodes show very good linearity with the reactor power monitoring system despite the transient radiation induced attenuation observed in the optical fibers. The radio-luminescent light shows steady values with around 5% of variations over the 15 transients for low OH fibers and high OH fibers. Low OH tends to overestimate the FWHM of the power peak by 1–4%.