ABSTRACT While there is an ample body of literature in the anthropology of moralities there is a surprising dearth of research on conscience per se. In Malta over the last ten years there has been a proliferation of a public discourse of ‘conscience’ – its affordances, freedoms and its legal safeguards. This has been the result of debates over reforms leading to the liberalization of sexual and family life, including most recently debates over the legalization of abortion. While the language of conscience in various human rights instruments claims a universal character its meanings, inflections and significance can vary in important ways. There is a blurred boundary between conscience and religion. This paper examines the ways in which conscience is deployed and the significance of the appeals to a national conscience in a European confessional state. It looks at the specific meanings of conscience in Malta and a brief lexical and political history It then moves on to look at the ways objections of conscience are framed in contemporary Malta in light of theological debates and their ramifications in Catholic Malta.