Detective Quantum Efficiency Research Articles

Measurement of the biphoton second-order correlation function with analog detectors.

An experimental scheme and data processing approaches are proposed for measuring by analog photo detectors the normalized second-order correlation function of the biphoton field generated under spontaneous parametric down-conversion. Obtained results are especially important for quantum SPDC-based technologies in the long-wave spectral ranges, where it is difficult to use the single-photon detector at least in one of the two biphoton channels. The methods of discrimination of analog detection samples are developed to eliminate the negative influence of the detection noises and get quantitatively true values of both the correlation function and the detector quantum efficiency. The methods are demonstrated depending on whether two single-photon avalanche photo detectors are used in both SPDC channels, or at least one single-photon detector is replaced by a photo-multiplier tube which cannot operate in the photon counting mode.

MAMMO_QC: Free software for quality control (QC) analysis in digital mammography and digital breast tomosynthesis compliant with the European guidelines and EUREF/EFOMP protocols

Quality Control (QC) tests in mammography are very important, since mammograms have been used as a population-based screening test for more than 30 years and QCs lead to better image quality and radiation safety for patients. European guidelines, EUREF and EFOMP protocols provide comprehensive QC guidelines for digital mammography (DM) and digital breast tomosynthesis (DBT) units, respectively. We developed a novel, fast, free and platform independent software (named MAMMO_QC) for QC performance tests in DM and tomosynthesis, based on the aforementioned guidelines. MAMMO_QC consists of a series of ImageJ plugins for DM and DBT. It does not require any programming knowledge and can be used to evaluate several performance parameters, such as pre-sampled modulation transfer function (pMTF), normalised noise power spectrum (NNPS), detective quantum efficiency (DQE), contrast-detail analysis based on the CDMAM 3.4 and 4.0 test tools, homogeneity and artefacts, automatic exposure control (AEC) performance. The user can use MAMMO_QC for acceptance, commissioning and routine QC performance analysis based on the European guidelines. We validated our results against well-established software products used in mammography and DBT (i.e., COQ, OBJ_IQ_reduced and Artinis CDMAM Analyzer). All the average relative differences were within 5.5%, and several years of usage and testing allows us to consider MAMMO_QC as an accurate and reliable tool for QC on DM and DBT systems. Our developed software for DM and DBT computes almost all the parameters stated in the European, EUREF and EFOMP guidelines. To the best of our knowledge, no such software has been developed so far.

Recent Progress in the Development of a-Se/CMOS Sensors for X-ray Detection

Amorphous selenium (a-Se) is a glass-former capable of deposition at high rates by thermal evaporation over a large area. It was chosen as a direct conversion material due to its appealing properties for imaging in both low and high X-ray energy ranges (<30 keV and <30 keV, respectively). It has a bandgap of 2.2 eV and can achieve high photodetection efficiency at short wavelengths less than 400 nm which makes it appealing for indirect conversion detectors. The integration of a-Se with readout integrated circuits started with thin-film transistors for digital flat panel X-ray detectors. With increasing applications in life science, biomedical imaging, X-ray imaging, high energy physics, and industrial imaging that require high spatial resolution, the integration of a-Se and CMOS is one direct way to improve the high-contrast visualization and high-frequency response. Over the past decade, significant improvements in a-Se/CMOS technologies have been achieved with improvements to modulation transfer function and detective quantum efficiency. We summarize recent advances in integrating and photon-counting detectors based on a-Se coupled with CMOS readout and discuss some of the shortcomings in the detector structure, such as low charge conversion efficiency at low electric field and high dark current at high electric field. Different pixel architectures and their performance will be highlighted.

Quantum state truncation using an optical parametric amplifier and a beam splitter

We present a scheme of quantum state truncation in the Fock basis (quantum scissors), based on the combined action of a nondegenerate optical parametric amplifier and a beamsplitter. Differently from previously proposed linear-optics-based quantum scissors devices, which depend on reliable Fock states sources, our scheme requires only readily available Gaussian states, such as coherent states inputs (vacuum state included). A truncated state is generated after performing photodetections in the global state. We find that, depending on which output ports each of the two photodetectors is positioned, different types of truncated states may be produced: i) states having a maximum Fock number of $N$, or ii) states having a minimum Fock number $N$. In order to illustrate our method, we discuss an example having as input states a coherent state in the beamsplitter and vacuum states in the amplifier, and show that the resulting truncated states display nonclassical properties, such as sub-Poissonian statistics and squeezing. We quantify the nonclassicality degree of the generated states using the Wigner-Yanase skew information measure. For complementarity, we discuss the efficiency of the protocol, e.g., generation probability as well as the effects of imperfections such as the detector's quantum efficiency and dark counts rate.

A detective quantum efficiency for spectroscopic X-ray imaging detectors.

Spectroscopic X-ray detectors (SXDs) are under development for X-ray imaging applications. Recent efforts to extend the detective quantum efficiency (DQE) to SXDs impose a barrier to experimentation and/or do not provide a task-independent measure of detector performance. The purpose of this article is to define a task-independent DQE for SXDs that can be measured using a modest extension of established DQE-metrologymethods. We defined a task-independent spectroscopic DQE and performed a simulation study to determine the relationship between the zero-frequency DQE and the ideal-observer signal-to-noise ratio (SNR) of low-frequency soft-tissue, bone, iodine, and gadolinium signals. In our simulations, we used calibrated models of the spatioenergetic response of cadmium telluride (CdTe) and cadmium-zinc-telluride (CdZnTe) SXDs. We also measured the zero-frequency DQE of a CdTe detector with two energy bins and of a CdZnTe detector with up to six energy bins for an RQA9 spectrum and compared with modelpredictions. The spectroscopic DQE accounts for spectral distortions, energy-bin-dependent spatial resolution, interbin spatial noise correlations, and intrabin spatial noise correlations; it is mathematically equivalent to the squared SNR per unit fluence of the generalized least-squares estimate of the height of an X-ray impulse in a uniform noisy background. The zero-frequency DQE has a strong linear relationship with the ideal-observer SNR of low-frequency soft-tissue, bone, iodine, and gadolinium signals, and can be expressed in terms of the product of the quantum efficiency and a Swank noise factor that accounts for DQE degradation due to, for example, charge sharing (CS) and electronic noise. The spectroscopic Swank noise factor of the CdTe detector was measured to be 0.81 0.04 and 0.83 0.04 with and without anticoincidence logic for CS suppression, respectively. The spectroscopic Swank noise factor of the CdZnTe detector operated with four energy bins was measured to be 0.82 0.02 which is within 5% of the theoretical value. The spectroscopic DQE defined here is (1) task-independent, (2) can be measured using a modest extension of existing DQE-metrology methods, and (3) is predictive of the ideal-observer SNR of soft-tissue, bone, iodine, and gadolinium signals. For CT applications, the combination of CS and electronic noise in CdZnTe spectroscopic detectors will degrade the zero-frequency DQE by 10%-20% depending on the electronic noise level and pixel size.

Quantitative Image Quality Metrics of the Low-Dose 2D/3D Slot Scanner Compared to Two Conventional Digital Radiography X-ray Imaging Systems.

The aim of this study was to determine the quantitative image quality metrics of the low-dose 2D/3D EOS slot scanner X-ray imaging system (LDSS) compared with conventional digital radiography (DR) X-ray imaging systems. The effective detective quantum efficiency (eDQE) and effective noise quantum equivalent (eNEQ) were measured using chest and knee protocols. Methods: A Nationwide Evaluation of X-ray Trends (NEXT) of a chest adult phantom and a PolyMethylmethacrylate (PMMA) phantom were used for the chest and knee protocols, respectively. Quantitative image quality metrics, including effective normalised noise power spectrum (eNNPS), effective modulation transfer function (eMTF), eDQE and eNEQ of the LDSS and DR imaging systems were assessed and compared. Results: In the chest acquisition, the LDSS imaging system achieved significantly higher eNEQ and eDQE than the DR imaging systems at lower and higher spatial frequencies (0.001 ≤ p ≤ 0.044). For the knee acquisition, the LDSS imaging system also achieved significantly higher eNEQ and eDQE than the DR imaging systems at lower and higher spatial frequencies (0.001 ≤ p ≤ 0.002). However, there was no significant difference in eNEQ and eDQE between DR systems 1 and 2 at lower and higher spatial frequencies (0.10 < p < 1.00) for either chest or knee protocols. Conclusion: The LDSS imaging system performed well compared to the DR systems. Thus, we have demonstrated that the LDSS imaging system has the potential to be used for clinical diagnostic purposes.

Characterization of predictable quantum efficient detector in terms of optical non-linearity in the visible to near-infrared range

The characteristics of a predictable quantum efficient detector (PQED) in terms of optical non-linearity in the visible to near-infrared range were investigated under zero-bias and reverse-bias voltage conditions. In the zero-bias condition, linear behavior was observed in the wavelength from 405 nm to 1060 nm in the photocurrent range of 1 nA to 10 μA, and saturation occurred for photocurrents over 10 μA for all wavelengths. In the reverse-bias voltage of 10 V, the linear behavior was observed in the photocurrent range of 64 nA to 1 mA except for the wavelength of 1060 nm, and the saturation photocurrent increased up to 1 mA. The supralinearity value at 1060 nm increased sharply from the photocurrent of 100 μA, and its maximum value reached up to 0.34% at the photocurrent of 1 mA because of the back surface recombination and the longer absorption length. The spectral linearity results of the PQED help us to understand the charge-carrier loss mechanism in the PQED, and would lead to more accurate optical measurement with it.

Performance of a visible light photon counting imaging detector for weak light intensities

In this study, a visible light photon-counting imaging detector was developed for weak light intensities, such as biofluorescence and photon-counting 3D imaging radars. The proposed visible light photon-counting imaging detector was based on a semitransparent S25 photocathode able of responding to visible light or even near-infrared wavelengths. The detector adopted image charge readout mode through high-resistance Ge layer receiver of electron cloud from the microchannel plate. The performance of the as-obtained visible light photon-counting imaging detector was tested in existing readout electronics and newly designed position-sensitive anodes. The quantum efficiency of the as-prepared detector reached 13.4% (@532 nm) with spatial resolution better than 100 μm. Preliminary imaging results of real objects with commercial lens and detector were also obtained and applied to ultra-weak light detection. In sum, these results look promising for future applications in photon-counting radars and biofluorescence imaging.

Side Channels of Information Leakage in Quantum Cryptography: Nonstrictly Single-Photon States, Different Quantum Efficiencies of Detectors, and Finite Transmitted Sequences

Side Channels of Information Leakage in Quantum Cryptography: Nonstrictly Single-Photon States, Different Quantum Efficiencies of Detectors, and Finite Transmitted Sequences

A comparison between higher-order nonclassicalities of superposition engineered coherent and thermal states

We consider an experimentally obtainable superposition (SUP) operator, defined by using a generalized superposition of products of field annihilation (a) and creation (a†) operators of the type A = saa† + ta†a with s2 + t2 = 1. We apply this SUP operator on coherent and thermal quantum states, and the states thus produced are referred to as SUP-operated coherent state (SOCS) and SUP-operated thermal state (SOTS), respectively. In the present work, we report a comparative study between the higher-order nonclassical properties of SOCS and SOTS. The comparison is performed by using a set of nonclassicality witnesses (e.g., higher-order anti-bunching, higher-order sub-Poissonian photon statistics, higher-order squeezing, Agarwal–Tara parameter, Klyshko’s condition). The existence of higher-order nonclassicalities in SOCS and SOTS have been investigated for the first time. In view of possible experimental verification of the proposed scheme, we present exact calculations to reveal the effect of non-unit quantum efficiency of quantum detector on higher-order nonclassicalities.

Theoretical investigation of the signal performance of HgI2 x-ray converters incorporating a Frisch grid structure at mammographic energies

Active matrix, flat-panel imagers (AMFPIs) suffer from decreased detective quantum efficiency under conditions of low dose per image frame (such as for digital breast tomosynthesis, fluoroscopy and cone-beam CT) due to low signal compared to the additive electronic noise. One way to address this challenge is to introduce a high-gain x-ray converter called particle-in-binder mercuric iodide (PIB HgI2) which exhibits 3–10 times higher x-ray sensitivity compared to that of a-Se and CsI:Tl converters employed in commercial AMFPI systems. However, a remaining challenge for practical implementation of PIB HgI2 is the high level of image lag, which is believed to largely originate from the trapping of holes. Towards addressing this challenge, this paper reports a theoretical investigation of the use of a Frisch grid structure embedded in the converter to suppress hole signal—which would be expected to reduce image lag. The grid acts as a third electrode sandwiched between a continuous top electrode and pixelated bottom electrodes having a 100 μm pitch. Signal properties of such a detector are investigated as a function of VDR (the ratio of the voltage difference between the electrodes in the region below the grid to that above the grid), grid pitch (the center-to-center distance between two neighboring grid wires) and R GRID (the ratio of grid wire width to grid pitch) for mammographic x-ray energies. The results show that smaller grid pitch suppresses hole signal to a higher degree (up to ∼96%) while a larger gap between grid wires and higher VDR provide minimally impeded electron transport. Examination of the tradeoff between maximizing electron signal and minimizing hole signal indicates that a grid design having a grid pitch of 20 μm with R GRID of 50% and 65% provides hole signal suppression of ∼93% and ∼95% for VDR of 1 and 3, respectively.

Improvements in beam’s eye view fiducial tracking using a novel multilayer imager

Purpose. Electronic portal image devices (EPIDs) have been investigated previously for beams-eye view (BEV) applications such as tumor tracking but are limited by low contrast-to-noise ratio and detective quantum efficiency. A novel multilayer imager (MLI), consisting of four stacked flat-panels was used to measure improvements in fiducial tracking during liver stereotactic body radiation therapy (SBRT) procedures compared to a single layer EPID. Methods. The prototype MLI was installed on a clinical TrueBeam linac in place of the conventional DMI single-layer EPID. The panel was extended during volumetric modulated arc therapy SBRT treatments in order to passively acquire data during therapy. Images were acquired for six patients receiving SBRT to liver metastases over two fractions each, one with the MLI using all 4 layers and one with the MLI using the top layer only, representing a standard EPID. The acquired frames were processed by a previously published tracking algorithm modified to identify implanted radiopaque fiducials. Truth data was determined using respiratory traces combined with partial manual tracking. Results for 4- and 1-layer mode were compared against truth data for tracking accuracy and efficiency. Tracking and noise improvements as a function of gantry angle were determined. Results. Tracking efficiency with 4-layers improved to 82.8% versus 58.4% for the 1-layer mode, a relative improvement of 41.7%. Fiducial tracking with 1-layer returned a root mean square error (RMSE) of 2.1 mm compared to 4-layer RMSE of 1.5 mm, a statistically significant (p < 0.001) improvement of 0.6 mm. The reduction in noise correlated with an increase in successfully tracked frames (r = 0.913) and with increased tracking accuracy (0.927). Conclusion. Increases in MV photon detection efficiency by utilization of a MLI results in improved fiducial tracking for liver SBRT treatments. Future clinical applications utilizing BEV imaging may be enhanced by including similar noise reduction strategies.

Measurement of entropy and quantum coherence properties of two type-I entangled photonic qubits

AbstractUsing the type-I SPDC process in BBO nonlinear crystal, we generate a polarization-entangled state near to the maximally-entangled Bell-state with high-visibility (high-brightness) 98.50 ± 1.33% (87.71 ± 4.45%) for HV (DA) basis. We calculate the CHSH version of the Bell inequality, as a nonlocal realism test, and find a strong violation from the classical physics or any hidden variable theory, S = 2.71 ± 0.10. Via measuring the coincidence count rate in the SPDC process, we obtain the quantum efficiency of single-photon detectors around (25.5 ± 3.4)%, which is in good agreement to their manufacturer company. As expected, we verify the linear dependency of the CC rate vs. pump power of input CW-laser, which may yield to find the effective second-order susceptibility crystal. Using the theory of the measurement of qubits, includes a tomographic reconstruction of quantum states due to the linear set of 16 polarization-measurement, together with a maximum-likelihood-technique, which is based on the numerical optimization, we calculate the physical non-negative definite density matrices, which implies on the non-separability and entanglement of prepared state. By having the maximum likelihood density operator, we calculate precisely the entanglement measures such as Concurrence, entanglement of formation, tangle, logarithmic negativity, and different entanglement entropies such as linear entropy, Von-Neumann entropy, and Renyi 2-entropy. Finally, this high-brightness and low-rate entangled photons source can be used for short-range quantum measurements in the Lab.

Assessment of Multienergy Interpixel Coincidence Counters (MEICC) for Charge Sharing Correction or Compensation for Photon Counting Detectors With Boxcar Signals.

Recently, multi-energy inter-pixel coincidence counter (MEICC) has been proposed for charge sharing correction and compensation for photon counting detectors (PCDs), which uses energy-dependent coincidence counters to record coincident events between multiple energy windows of a pixel-of-interest and those of neighboring pixels. A Monte Carlo (MC) simulation study was performed to assess the performance of MEICC; however, the performance might have been overestimated in a previous study. The charge sharing increases the number of photons recorded at a PCD pixel at the expense of the spatial resolution, and therefore, when spatially uniform flat-field x-ray signals are used, it gives PCDs with charge sharing more signals than a PCD without charge sharing. In this paper, we propose to use spatially modulated boxcar signals for evaluating the performances for high spatial frequency tasks because they provide consistent signals regardless of the presence of absence of charge sharing. The flat-field signals must be used for low spatial frequency tasks. We assessed the performances of MEICC and other PCDs with both flat-field signals and boxcar signals, with optimal threshold energies, and with two different pixel sizes. As it is expected, normalized Cramér-Rao lower bounds (nCRLBs) measured with the boxcar signals were worse than those with flat-field signals in general. The nCRLBs of MEICC with 225-μm pixel were close to the current 450-μm PCD. We studied a combination of flat-field signals and N×N super-pixels, where the output of N×N pixels were added, using an MC simulation and a simple charge sharing counting model. The study showed that charge sharing had two opposing impacts on the conventional CT imaging-a negative impact with double-counting among N×N pixels and a positive impact with single-counting spill-in and spill-out across the super-pixel boundary-and the positive impact diminished with increasing N. A use of large N×N super-pixels such as N≥25 was suggested to approximate the zero-frequency detection quantum efficiency of PCD with charge sharing.

FastCAT: Fast cone beam CT (CBCT) simulation.

To develop fastCAT, a fast cone-beam computed tomography (CBCT) simulator. fastCAT uses pre-calculated Monte Carlo (MC) CBCT phantom-specific scatter and detector response functions to reduce simulation time for megavoltage (MV) and kilovoltage (kV) CBCT imaging. Pre-calculated x-ray beam energy spectra, detector optical spread functions and energy deposition, and phantom scatter kernels are combined with GPU raytracing to produce CBCT volumes. MV x-ray beam spectra are simulated with EGSnrc for 2.5- and 6MeV electron beams incident on a variety of target materials and kV x-ray beam spectra are calculated analytically for an x-ray tube with a tungsten anode. Detectors were modeled in Geant4 extended by Topas and included optical transport in the scintillators. Two MV detectors were modeled-a standard Varian AS1200 GOS detector and a novel CWO high detective quantum efficiency detector. A kV CsI detector was also modeled. Energy-dependent scatter kernels were created in Topas for two 16cm diameter phantoms: A Catphan 515 contrast phantom and an anthropomorphic head phantom. The Catphan phantom contained inserts of 1-5mm in diameter of six different tissue types: brain, deflated lung, compact and cortical bone, adipose, and B-100. fastCAT simulations retain high fidelity to measurements and MC simulations: MTF curves were within 3.5% and 1.2% of measured values for the CWO and GOS detectors, respectively. HU values and CNR in a fastCAT Catphan 515 simulation were seen to be within 95% confidence intervals of an equivalent MC simulation for all of the tissues with root mean squared errors less than 16 HU and 1.6 in HU values and CNR comparisons, respectively. The anthropomorphic head phantom CWO detector CBCT image resulted in much higher tissue contrast and lower noise compared to the GOS detector CBCT image. A fastCAT simulation of the Catphan 515 module with an image size of 1024 1024 10 voxels took 61s on a GPU while the equivalent Topas MC was estimated to take more than 0.3CPU years. We present an open source fast CBCT simulation with high fidelity to MC simulations. The fastCAT python package can be found at https://github.com/jerichooconnell/fastCAT.git.

Measurement of the Probability of a Binary Symbol «0» Erasing in a Single-Photon Asynchronous Communication Channel with a Receiver Based on a Photon Counter

Receiving modules of single-photon communication channels should provide the least loss of transmitted information when measuring low-power optical signals. In this regard, it is advisable to use photon counters. They are highly sensitive, but are characterized by data logging errors. Therefore, the purpose of this work was to investigate the effect of the intensity of the recorded optical radiation during the transmission of binary symbols «0» on the probability of erasing these symbols in a single-photon communication channel containing a photon counter based on an avalanche photodetector as a receiving module with a passive avalanche suppression scheme.The lower and upper threshold levels of pulses recorded at the output of the photon counter, as well as the statistical distributions of the mixture of the number of dark and signal pulses at the output of the photon counter when registering binary symbols «0» Pst0( N ) and «1» Pst1( N ) were determined. For this, a technique was used to reduce information loss. As a result, the minimum probability of erasing binary symbols «0» P(–/0) was achieved.The performed experimental results showed that to achieve the minimum probability of erasing binary symbols «0» P(–/0) = 0,11·10−2, it is important to select not only the intensity of the used optical radiation J , but also the supply voltage of the avalanche photodetector U, at which the dead time of the photon counter is −2 minimal, and its quantum detection efficiency is maximum: J0 ≥ 98,94·10−2 rel. units and U = 52,54 V.

The response of thick (10 μm) AlInP x-ray and γ-ray detectors at up to 88 keV

The development of new x-ray and γ-ray spectrometers based on AlInP photodiodes with increased quantum detection efficiency and improved energy resolution is reported. The spectroscopic responses of two AlInP p+–i–n+ mesa photodiodes (10 μm i layer, the thickest so far reported) were investigated at photon energies from 4.95 to 88.03 keV; the detectors and preamplifier were operated at 30 °C. Energy resolutions (full width at half maximum) of 750 ± 40 eV and 850 ± 30 eV at 4.95 keV were achieved with the two detectors. The energy resolution deteriorated with increasing photon energy; this was in accordance with the increasing Fano noise with energy and suggested negligible incomplete charge collection noise across the photon energy range investigated. The measured voltage output of each spectrometer was found to be linear as a function of incident x-ray photon energy. The count rate (measured at 8.63 keV) was also found to linearly increase with incoming x-ray photon flux for the investigated spectrometers. These results, which were obtained using the thickest AlInP photodiodes produced so far, suggest that AlInP detectors are highly promising candidates for future uncooled x-ray and γ-ray spectrometers.

The fast multi-frame X-ray diffraction detector at the Dynamic Compression Sector.

A multi-frame, X-ray diffraction (XRD) detector system has been developed for use in time-resolved XRD measurements during single-event experiments at the Dynamic Compression Sector (DCS) at the Advanced Photon Source (APS). The system is capable of collecting four sequential XRD patterns separated by 153 ns, the period of the APS storage ring in the 24-bunch mode. This capability allows an examination of the temporal evolution of material dynamics in single-event experiments, such as plate impact experiments, explosive detonations, and split-Hopkinson pressure bar experiments. This system is available for all user experiments at the DCS. Here, the system description and measured performance parameters (detective quantum efficiency, spatial and temporal resolution, and dynamic range) are presented along with procedures for synchronization and image post-processing.

Estimating the Product of the X-ray Spectrum and Quantum Detection Efficiency of a CT System and Its Application to Beam Hardening Correction.

Lab-based X-ray computed tomography (XCT) systems use X-ray sources that emit a polychromatic X-ray spectrum and detectors that do not detect all X-ray photons with the same efficiency. A consequence of using a polychromatic X-ray source is that beam hardening artefacts may be present in the reconstructed data, and the presence of such artefacts can degrade XCT image quality and affect quantitative analysis. If the product of the X-ray spectrum and the quantum detection efficiency (QDE) of the detector are known, alongside the material of the scanned object, then beam hardening artefacts can be corrected algorithmically. In this work, a method for estimating the product of the X-ray spectrum and the detector’s QDE is offered. The method approximates the product of the X-ray spectrum and the QDE as a Bézier curve, which requires only eight fitting parameters to be estimated. It is shown experimentally and through simulation that Bézier curves can be used to accurately simulate polychromatic attenuation and hence be used to correct beam hardening artefacts. The proposed method is tested using measured attenuation data and then used to calculate a beam hardening correction for an aluminium workpiece; the beam hardening correction leads to an increase in the contrast-to-noise ratio of the XCT data by 41% and the removal of cupping artefacts. Deriving beam hardening corrections in this manner is more versatile than using conventional material-specific step wedges.

Detector thickness effects on nanosecond-gated imager response.

Hybrid CMOS multi-frame imagers with exposure times down to ∼2ns have made significant impacts in high energy density physics and inertial confinement fusion research. The detector thickness is a key parameter in both detector quantum efficiency and temporal response. The Icarus hybrid CMOS imager has been fabricated with Si detector thicknesses of 8, 25, and 100 µm. The temporal response of imaging sensors with exposure time down to 2ns has been examined and compared to directly measured photodiode current. The 100-μm thick variant displays extended features related to charge carrier collection and is more susceptible to field collapse. We also demonstrate charge collection time effects on spatial response.