WHO Quality Research Articles

Australian link worker social prescribing programs: An integrative review.

Link worker social prescribing programs are gaining recognition in Australia for addressing health and social needs outside routine medical care. The evaluation of these programs is essential for informing future social prescribing programs, research and evolving policy. However, diverse outcome evaluation measures present challenges for benchmarking across link worker social prescribing programs. An integrative review was conducted to identify and describe outcome domains and measures, and the methodological approaches and evaluation designs of link worker social prescribing programs in Australia. Comprehensive searches of the literature on link worker social prescribing programs in Australia were conducted across 14 electronic databases. In order to reduce the risk of bias, study selection and data extraction were conducted independently by multiple authors, and included studies underwent quality and risk of bias assessment using the standardised Mixed Methods Appraisal Tool. Six studies met the inclusion criteria. Outcome domains were categorised into 'person-level', 'system-level' and 'program implementation' domains. Despite the variation in participant groups, the 'person-level' domains of global well-being and social well-being were consistently evaluated. While measurement tools varied significantly, the WHO Quality of Life Brief Assessment and short-form UCLA Loneliness Scale were most commonly applied. At the system level, health service utilisation was primarily evaluated. This integrative review reports on the current state of evidence in Australia, with the potential to track changes and trends over time. Developing a core outcome set, incorporating stakeholder and consumer contributions for benchmarking aligned with the healthcare landscape is recommended. The findings may guide the refining of social prescribing initiatives and future research, ensuring methodological robustness and alignment with individual and community needs.

Association between long-term PM2.5 exposure and mortality on Sumatra Island: Indonesian Family Life Survey (IFLS) 2000-2014.

The concentration of PM2.5 (particulate matter with a diameter < 2.5µm) on Sumatra Island has increased, mainly because of forest and peatland fires, transportation, and industry. Biomass burning releases partially burned carbon into the atmosphere, resulting in a smoky haze containing PM2.5. Air quality has deteriorated quickly, and PM2.5 has become a major health hazard in Indonesia. Studies on long-term exposure to PM2.5 have indicated its associations with both morbidity and mortality. Here, we measured long-term (2000-2014) exposure to PM2.5 on the basis of satellite-derived aerosol optical depth measurements (1 × 1 km2) used to predict ground-level PM2.5 concentrations. Additionally, population data on Sumatra Island residents from the fourth wave of the Indonesian Family Life Survey (IFLS) were obtained. We investigated the association between long-term PM2.5 exposure and mortality with a retrospective cohort study design. A total of 2409 subjects aged ≥ 40years participated in the IFLS-3 beginning in November 2000, and we examined mortality outcomes until the IFLS-5 in September 2014. We used Cox regression models to calculate hazard ratios (HRs) of mortality associated with PM2.5 exposure. According to the adjusted model, the mortality HRs per 10µg/m3 increase in PM2.5 concentration were 1.10 (95% CI 1.03, 1.17) for all natural causes, 1.17 (95% CI 1.05, 1.25) for cardiovascular causes, and 1.19 (95% CI 1.04, 1.36) for respiratory causes. Long-term exposure to PM2.5 was associated with all-natural, cardiovascular, and respiratory mortality on Sumatra Island, where PM2.5 levels exceed the WHO and US-EPA air quality standards.

Quality of life and spiritual needs of patients diagnosed with cancer in a tertiary hospital in southwestern Nigeria

ObjectiveIn Africa, cancer is considered a death sentence. Its impact can be debilitating for the patient and those who care for them. This study therefore assessed the spiritual needs and Quality of life of Cancer patients in a tertiary hospital in Nigeria. MethodsThis study utilized a cross-sectional descriptive design. We systematically recruited 302 cancer patients who visited the cancer registry and outpatient departments. A standardized and validated Spiritual needs questionnaire (SpNQ) and WHO Quality of Life (WHOQL) were used to collect data. Data was analyzed with SPSS version 23 with a significance level set at p < 0.05. ResultsThe preponderance cancer among respondents was breast cancer 146 (48.4%) followed by prostate cancer 41 (13.6%). Most of the respondents admitted having “strong” spiritual needs. Categorization of the spiritual need score was below average in 20% of the respondents which indicated those with low spiritual needs and the majority 241 (79.8%) of the patients had high spiritual needs. Most respondents had poor quality of life in all four domains. The spiritual care needs of respondents were significantly associated with the quality of life of the respondents particularly in the psychological domain (p = 0.040) and social domain (p = 0.005). ConclusionThis study revealed high spiritual needs and poor quality of life among cancer patients. Healthcare practitioners should provide for the spiritual needs of cancer patients to enhance their quality of life.

Multimodal intervention on perception and quality of life of geriatric clients regarding health promotional outcomes at a selected hospitals, Kolar, Karnataka, India

ABSTRACT Background of Study: Old age is a privilege for a second childhood and a new stage of opportunity and strength. Older adults are the most rapidly growing segment of the population. By 2050, 80% of all older people will live in low- and middle-income countries. Purpose: To evaluate the effectiveness of multimodal intervention on perception and quality of life among geriatric clients. Methods: Quantitative approach quasi-experimental interventional controlled study with pre-test, post-test design and follow-up for two months, adopted by using purposive sampling technique among 120 geriatric clients who gave consent for participation in the study at two different settings of hospitals from July 2022 to January 2023, Kolar. After obtaining Central Ethics Committee approval, data was obtained using the structured perception questionnaire and WHO Quality of Life questionnaire, and the Multimodal Intervention package consisting of a snake and ladder health promotion strategies game, educational video, and informational pamphlet distributed to the experimental group, whereas routine care was given to the control group followed by post-test group on the 30th and 60th day. Reinforcement was carried out by the investigator on a fortnightly basis reminders through messages. Data were analyzed by using descriptive and inferential statistics such as repeated measures of ANOVA, independent ‘t’- test, paired ‘t-test, and Chi-square. Results: A perception significant effect was demonstrated in the experimental group with enhanced mean, standard deviation from pre-test to post-test I and Post-test II found to be 35.1 ± 7.9, 46.3 ± 6.1, and 48.3 ± 4.7, respectively, without significant changes in the control group. Concerning quality of life, important variations were demonstrated in the experimental group with enhanced mean, SD from pre-test to post-test I and Post-test II found to be 54.76 ± 10.39, 74.15 ± 6.75 and 77.71 ± 4.99, respectively, without any significant changes in the control group. Conclusion: Geriatric population was the biggest beneficiary, multimodal intervention was proven to be effective and can be implemented in hospitals and community settings in improving the perception and quality of life of senior clients to foster healthy aging. CTRI Trial Reg no: CTRI/2021/07/034632.

Relationship of workload with fatigue and sleep quality in female exercisers

Fatigue is a critical issue for female exercisers that may lead to medical errors, degradation in performance, decreased mental acuity, and social problems. Poor sleep quality is also a contributing factor to the fatigue experienced by female exercisers. Overwork is a factor causing poor sleep quality in female exercisers. The present study aimed to investigate the relationship between workload, fatigue, and sleep quality among female exercisers in the Sleman Regency District. A cross-sectional study was conducted from December 2023 to March 2024 using a self-reported questionnaire. The questionnaire included the Workload questionnaire adapted from the National Aeronautics and Space Administration Task Load Index, the Leeds Sleep Evaluation Questionnaire (LSEQ), and the Subjective Self Rating of Fatigue Assessment Scale (FAS) from the WHO Quality of Life Assessment Instrument (WHOQOL-EF) with 200 respondents in Sleman Regency. The PLS equation model was used to analyze the relationship between workload, sleep quality, fatigue, and the indicators of each instrument. The results showed that female exercisers who were over 40 years old, had children at home, had informal work, did daily exercise in the evening, and had a work schedule in the night had a higher risk of fatigue and poorer sleep quality than those below 40 years old who didn’t have children at home, had formal work, did daily exercise in the morning, and had a work schedule in the morning. A subjective self-rating test was used to measure fatigue, sleep quality, and workload. The training load and intensity of exercise programs influenced fatigue levels, which affected sleep quality. Female exercisers may face challenges balancing exercise with other commitments, such as family responsibilities, leading to overtraining and fatigue. The PLS model test showed a significant relationship between sleep quality and the level of perceived fatigue (p-value = 0.000). Workload significantly impacts sleep quality and fatigue risk in female exercisers. Therefore, managing workload is crucial to improving sleep quality and reducing fatigue risk.

PREDICTIVE ROLE OF MATERNAL DEPRESSIVE SYMPTOMS AND PERCEIVED QUALITY OF LIFE ON POSTNATAL MOTHER-INFANT BONDING

This cross-sectional study was focused on the predictive role of maternal depressive symptoms and perceived quality of life on postnatal mother-infant bonding. Research show that impaired postnatal bonding has a negative long-term effect on child’s development. Relevant literature also acknowledges a scientific gap in the understanding of the relationship between maternal mental health and the quality of postnatal mother-infant bonding. Respondents were 162 women in the first 12 months after childbirth, advising with gynecologist in maternity hospitals in the Republic of North Macedonia. Edinburgh postnatal depression scale, subscales of psychological and environmental domain of the WHO Quality of Life Scale-brief, and Postpartum Bonding Questionnaire were applied to measure study variables. Results from hierarchical binary logistic regression showed that psychological domain of quality of life significantly predicted quality of postnatal bonding in the first and second block. However, its effect was suppressed in the third block when depressive symptoms variable was entered. The presence of depressive symptoms and environmental domain of the perceived quality of life significantly predicted postnatal mother-infant bonding. Findings confirmed the significant predictive relationship of maternal depressive symptoms and of environmental domain of mother’s perceived quality of life on the quality of postnatal boding. This gives reason for increased attention on development of mother–infant dyads during the postnatal period and on the importance of social support.

Psychological Distress and Quality of Life Among Military Trauma Patients.

Military trauma has a significant impact on soldiers, affecting many aspects of their lives, with the highest impact on their quality of life and psychological wellness. This study aimed to measure psychological distress and its relationship with the quality of life among Jordanian military trauma patients. A descriptive cross-sectional study was conducted in The Hashemite Protection Departments for military causalities in Amman, Irbid, and Al-Karuk. The authors used the WHO Quality of Life Scale-Brief and Trauma Symptoms Checklist-40 scales for assessing the quality of life and psychological distress among Jordanian military trauma patients. A total of 145 trauma survivors participated in the study and responded to all questionnaires out of 173 distributed. The study was approved by the institutional review board of Al-Zaytoonah University. The result of this study revealed that military trauma survivors had high levels of psychological distress with a mean of 85.66 (SD = 19.418). The subscale of "Dissociation symptoms" had the highest rating (M = 19.92, SD = 5.096), while the "sleep disorders" subscale had the lowest rating (M = 10.000, SD = 3.501). On the quality of life scale, a moderate level of quality of life resulted among the participants with a mean of 61.620 (SD = 17.190). The "general health" subscale scored the highest among the other domains (M = 18.241, SD = 5.434), while the "physical health" domain scored the lowest (M = 4.910, SD = 2.078). Furthermore, a statistically significant negative relationship between psychological distress and quality of life was reported (r =-0.178, P < .05). Jordanian injured military persons had a moderate quality of life level and high level of psychological distress. A structured follow-up program is required to be developed to improve those patients' health and quality of life. Furthermore, additional research is needed to investigate the impact of military trauma and services on soldiers in Jordan and the Middle East.

Evaluation of comparative efficacy of Celastrus paniculatus (Jyotishmati) capsule versus sertraline capsule in the management of Chittodvega (generalized anxiety disorder): protocol for a randomized controlled trial

Background Generalized anxiety disorder (GAD) (Chittodvega) is one among many types of mental disorders explained in Ayurveda. It can be defined as a Chitta (mind) + Udvega (anxiety)= Chittodvega- Anxious status of a mind. Celastrus paniculatus also known as Jyotishmati stimulates and improves the digestive fire and metabolism at a cellular level (Jatharagni and Majja dhatwagni). It can be correlated to GAD. GAD is characterized by feelings of threat, restlessness, irritability, sleep disturbance, and tension, and symptoms such as palpitations, dry mouth, and sweating. It affects women more frequently than men and prevalence rates are high in midlife (prevalence in females over age 35: 10%) and older subjects. In modern medicine the first-line psychological and pharmaceutical treatments are selective serotonin reuptake inhibitors (SSRIs) like sertraline (SNRIs). Aim and objectives To evaluate the comparative efficacy of Jyotishmati versus sertraline in the management of Chittodvega. Methods In this randomized active controlled double blind equivalence trial a total of 70 patients will be enrolled and divided into two equal groups. Patients between 20–50 years age of either gender having symptoms of Chittodvega and a Hamilton anxiety rating (HAM-A) scale score less than 24 (i.e., mild to moderate) will be selected for the study. In Group A, sertraline capsules 25 mg for first 7 days and then dose increased to 50 mg at bedtime for next 53 days and in Group B Jyotishmati Capsules 500 mg will be given twice a day after food with water for 60 days. Result and observation The patients will be assessed on the HAM-A scale, serum cortisol and WHO Quality of Life on day 0, 30, 60 and 90 and data will be analyzed using paired and unpaired t-tests for continuous variables and chi-square tests for categorical variables to evaluate whether treatments are equivalent. Trial registration CTRI No. REF/2023/07/069880 Date – 15/09/2023

Improving the rights of people with mental disorders in the Republic of Croatia

Abstract The mental health care system in the Republic of Croatia, despite the ongoing reform, is still based on hospital treatment. Hospitalizations due to mental disorders are in first place according to the length of stay. According to the annual report of the Ombudsman in the Republic of Croatia, 2% of hospitalizations due to mental disorders are involuntary hospitalization. Coercive measures and deprivation of business capacity are also often used. In order to reduce the number of coercive measures, involuntary hospitalizations and deprivation of professional capacity, it is necessary to increase mental health literacy and knowledge about human rights and the rights of persons with mental disorders, both among mental health experts and among patients and their families, as well as the general public. In order to increase knowledge and skills related to the rights of people with mental disorders, the Croatian Institute of Public Health, has been conducting WHO Quality Rights workshops in Croatian counties since 2019. The two-day workshops include all stakeholders: local politicians and decision-makers, associations of people with mental disorders and their families, employees in the mental health care system with the involvement of the media. So far, the training has been conducted in five major Croatian counties. The Quality Rights e-training platform has been translated into Croatian and the link to access the training is available online. In order to ensure the sustainability of the program and expand knowledge and skills, obtaining a certificate of completed Quality Right training became a requirement for passing the specialist exam in public health and in psychiatry. In five years of implementation of the program, the number of coercive measures in psychiatric hospitals decreased by 58%. Respect for human rights is a prerequisite for improving the mental health care system and the mental health. of both patients and the entire population. Key messages • Respect for human rights is necessary for the mental health of the population. • Knowledge and skills about the rights of patients with mental disorders reduce the rate of coercive measures.

Attachment Style, Interpersonal Dependency and Quality of Life Among Emerging Adult

An emerging adult typically is in a transitional phase from adolescence to full adulthood. Interpersonal dependency refers to a psychological state in which an individual relies heavily on others for emotional support, validation, and decision-making. Quality of life means an individual’s overall well-being and satisfaction with various aspects of their life. This study examines the connection between attachment style, interpersonal dependency and quality of life. 200 emerging adults of age 18-24 made up the sample, which include both males and females were collected from various colleges of Ernakulam and Kottayam district. Adult attachment style scale, Interpersonal dependency Inventory and WHO Quality of life brief scale were the instruments employed. The data was examined using the Spearman's correlation test, using SPSS version 28. In this present study there is a partial relationship between the subscales of attachment style, interpersonal dependency and quality of life. Some of the subscales of these variables are correlated and other subscales are non-correlated. There exists a positive correlation between some of the subscales of attachment style, interpersonal dependency and quality of life and the other subscales of attachment style, interpersonal dependency and quality of life was negatively correlated among emerging adults.

Effect of Group Motivational Enhancement Therapy in Patients with Opioid Dependence (on Maintenance Treatment): Study Protocol of a Randomized Controlled Trial

Background: Relapse and treatment dropout are key challenges in opioid use disorder that need effective intervention strategies. Motivation enhancement therapy may be effective in improving opioid use disorder treatment outcomes. Objective: To assess the effectiveness of group motivational enhancement therapy (GMET) in patients with opioid dependence. Methods: It is an open-label, two-arm, parallel-group, randomized controlled trial (RCT). Participants include patients with opioid dependence and on opioid maintenance treatment, aged between 18 and 60 years. The intervention consists of six GMET sessions, each lasting about 45 minutes. Assessments will be conducted at four time points—baseline, six weeks, four months, and six months—using the Kessler psychological distress scale (K10), Recovery and Relapse Prevention Inventory Diagnostic (RAPID), WHO Quality of Life-BREF, Harm Reduction Self-Efficacy Questionnaire and Stage of Change Readiness and Treatment Eagerness Scale for drugs (SOCRATES 8D). Conclusion: The customized GMET approach tailored to the specific needs of the local population is expected to enhance the effectiveness and feasibility of the intervention and its implementation.

Effects of peer-led education on knowledge, attitudes, practices of stoma care, and quality of life in bladder cancer patients after permanent ostomy.

To investigate the effects of peer-led intervention on knowledge, attitudes, and practices (KAP) of stoma care, as well as quality of life in bladder cancer patients post-permanent ostomy. A series of 340 eligible bladder cancer patients who underwent permanent ostomy from January 2019 to December 2022 were enrolled in this study. These participants were randomly assigned to the intervention group (peer-led intervention) and the control group (routine health intervention) using random number table, with 170 cases in each group. A 30-item questionnaire was used to evaluate knowledge, healthy attitudes, and healthy practices (KAP) of disease; the WHO Quality of Life-100 (WHOQOL-100) was utilized to assess the quality of life among patients; and the incidence of complications in two groups were also recorded during six-month intervention. For the comparison of continuous variables within and between groups, paired sample and independent t-test were applied. The categorical variables analyzed using x2 test or rank-sum test. After six-month intervention, 144 participants in the intervention group and 151 participants in the control group were finally retained in this study. The scores of the 20 items in KAP (including basic knowledge of disease, basic knowledge of ostomy, observation of stoma, etc.) in the intervention group were significantly higher than those in the control group (all p < 0.05); the scores of 12 items in WHOQOL-100 (including the positive feelings, thinking, learning, memory and concentration, etc.) in the intervention group were markedly higher than those in the control group, while negative feelings and dependence on medical support in the intervention group were significantly lower than those in the control group (all p < 0.05); the total rate of complications in the intervention group was significantly lower than that in the control group (18.31% vs. 31.13%, p < 0.05). The peer-led intervention has a positive effect on improving patients' KAP of stoma care and quality of life and reducing the rate of complications, which enables it to be a favorable intervention approach for patients with permanent ostomy.

Impact of COVID-19 Vaccination on Menstrual Cycle, Quality of Life and Perception on Fertility: A Mixed Methods Study of Women in Delhi-NCR

The COVID-19 pandemic presented extraordinary challenges which led individuals to make global efforts to develop a vaccine that could help battle the spread of the infection. The COVID-19 vaccine came as a sigh of relief for the world, but whilst we assess the positives, we must consider looking into the potential impacts it has had on aspects of health, including female reproductive health. The current study aimed at assessing the potential impacts that COVID-19 vaccination had on menstrual cycles and the perception of women about fertility-related issues following the jab through a comprehensive mixed methods design. A structured survey, using the Menstrual Symptom Questionnaire (MSQ) and WHO Quality of life scale was carried out with a diverse sample (n=500) of women (18-40 years) in the Delhi-NCR region, collecting data on menstrual cycle changes post receiving the Vaccine. Additionally, semi-structured interviews were conducted with a subset of the participants (n=15) to understand the perceptions of women about fertility-related issues following the Vaccine. The study suggests that most of the participants reported facing menstrual concerns such as missed periods, menstrual irregularities, excessive menstrual bleeding and increased cramping on the first day of their period. Through semi-structured interviews, the themes that emerged were fear regarding conception, early menopause, infertility, mood changes, anxiety, fatigue, less pain tolerance and problems with menstrual flow. Alongside, many had low scores on the quality-of-life questionnaire which was understood better through semi-structured interviews. Cognitive distortions were observed among participants while they explained their perceptions of the whole scenario. The study seeks to address a critical topic and fill knowledge gaps to understand the possible health impacts the COVID-19 vaccine has on women’s reproductive health. The study would contribute to creating scientific evidence and valuable insights for the health industry to understand any potential side effects the vaccine could have.

PROFILE OF PATIENTS WITH SLEEP COMPLAINTS IN A SECONDARY CARE HEALTH INSTITUTION IN THE CITY OF CAMPINAS, SÃO PAULO STATE

Objective: We report data of the profile of patients who sought our outpatient clinic for sleep disorders of the Faculty of Medicine of São Leopoldo Mandic Medical School, during the Week of Sleep, that took place in March, 2022. Methods: All participants responded to a form designed by the researcher, as well as to commonly used questionnaires in Sleep Research, such as the Epworth Sleepiness Scale (ESS), the Insomnia Severity Index (ISI), the Hospital Anxiety and Depression Scale, the STOP-BANG questionnaire for screening of apnea, and the WHO Quality of Life abbreviated questionnaire (WHOQOL-BREF). Results: 30 patients were evaluated, mean age 51.8 (± 14), 63% women. Main complaints were insomnia (63%), snore/apnea (23%) and excessive daytime sleepiness (10%). ESS scores were significantly higher among men, daytime nappers and alarm clock users. ISI scores were importantly associated with those who woke 2 or more times per night, while physically active, non-obese, normotensive people and those with Modified Mallampatti (MM) classes I and II scored significantly less in STOP-BANG. Obese, MM classes III-IV and people with abnormal cervical and abdominal circumferences performed markedly worse in Domain 1, while women, older people and alarm clock users went worse in Domain 4 of WHOQOL-BREF. Discussion: One or more sleep disturbances were detected in all seekers of Sleep Care, emphasizing the importance of these types of action.

Psychometric Properties of the World Health Organization Quality of Life Scale for Older Adults (WHO-QoL-Old) in a Mexican Population.

The present study aimed to contribute to analyzing the psychometric properties of the WHO Quality of Life Scale for Older Adults (WHO-QoL-Old) in a sample of older adults in Michoacán, Mexico. 111 older adults from Michoacán, Mexico, participated in the study. Confirmatory factor analysis (CFA) was conducted to test the fit of various models. Data analysis was performed using R Studio, considering the ordinal nature of the items in the model estimation method. Internal consistency was evaluated using the alpha coefficient (α) and McDonald's omega coefficient (ω). The CFA indicated that the six-correlated-factor model proposed theoretically showed a very good fit (χ2: 397.11, p < 0.001; CFI: 0.958; SRMR: 0.079; RMSEA: 0.079). The factors within the model demonstrated acceptable internal consistency, with an alpha coefficient ranging from 0.739 to 0.874 and an omega coefficient ranging from 0.748 to 0.882. It is concluded that the WHO-QoL-Old scale presents good psychometric properties for the Mexican older adult population.

Quality of life in patients with myelin oligodendrocyte glycoprotein antibody associated disease compared to patients with AQP4-IgG positive neuromyelitis optica spectrum disorders: A Korean multicenter study

BackgroundLittle is known about the quality of life (QOL) of patients with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). We compared QOL and associated factors in patients with MOGAD and aquaporin4 IgG (AQP4-IgG) positive neuromyelitis optica spectrum disorder (NMOSD). MethodsThis multicenter questionnaire study compared the QOL of 41 patients with MOGAD and 78 with AQP4-IgG positive NMOSD. Patients who were positive for AQP4-IgG or MOG antibodies were included. WHO Quality of Life Scale Brief Version was used to assess QOL in physical, psychological, social, and environmental domains. QOL, sleep quality, pain, fatigue, and depression were compared between the two groups. The factors associated with QOL in each group and the entire cohort were analyzed. ResultsThe proportion of patients with poor QOL was not significantly different between MOGAD (51.22 %) and AQP4-IgG positive NMOSD (58.97 %, p = 0.054). In the MOGAD group, the pain score (β=-1.032, p = 0.001) and depression score (β=-0.694, p = 0.007) were negatively associated with physical and psychological QOL, respectively. Sleep quality was negatively associated with physical (β=-1.506, p = 0.034) and psychological (β =-2.064, p = 0.033) QOL. When the entire cohort was analyzed, a positive MOG antibody was independently associated with worse psychological QOL (β=-8.998, p = 0.013) compared to positive AQP4-Ab after adjustment for sleep quality, depression, fatigue, and pain. ConclusionsThe overall QOL of the patients of MOGAD was comparable to that of AQP4-IgG positive NMOSD. Patients with MOGAD were experiencing sleep disorder, fatigue, and depression at similar degrees to those of patients with AQP4-IgG positive NMOSD. Further consideration of sleep quality and psychological QOL is required to improve QOL in patients with MOGAD.

Quality of Life and Depression in Premenstrual Dysphoric Disorder and Premenstrual Syndrome Among College Students

The symptoms before a woman’s period, Premenstrual Syndrome (PMS) and Premenstrual Dysphoric Disorder (PMDD) involve physical and emotional aspects. PMS and PMDD differ in symptom severity. Thus, the psychological effects are considerable and affect the individual’s physical state. The present study aims to investigate the quality of life and depression among college students with PMS and PMDD. Forty clinically diagnosed females with Premenstrual Dysphoric Disorder and 40 females with Premenstrual syndromes were sampled through purposive sampling method, the age range of 16 to 21 (Mean age 18.37, SD 1.63) years from Kapurthala, Punjab. WHO Quality of Life -BREF Hindi and Beck Depression Inventory-II were individually administered to both groups. The statistical analysis of descriptive and t-tests revealed that premenstrual dysphoric disorder exhibits a significantly low level of quality of life as compared to premenstrual syndrome. Premenstrual dysphoric disorder revealed significantly higher levels of depression as compared to premenstrual syndrome. The significant finding of the study is that adolescents with Premenstrual dysphoric disorder suffer from poor quality of life and Well-being. Study supporting female adolescents, especially those with severe Premenstrual dysphoric disorder, can enhance their quality of life and well-being through counseling, education, and lifestyle changes.

Quality of life and associated factors among primary caregivers of children and adolescents with neurodevelopmental disorders attending public hospitals in Addis Ababa, Ethiopia: a cross-sectional study.

Neurodevelopmental disorders are a set of disorders that negatively affect the acquisition of skills in a variety of developmental domains, including motor function, learning, socialization, language and cognition. However, there is no information available on the standard of living of Ethiopian primary caregivers of children and adolescents with neurodevelopmental disorders. Therefore, this study aimed to assess the quality of life (QOL) and associated factors among primary caregivers of children and adolescents with neurodevelopmental disorders in Addis Ababa, Ethiopia. A cross-sectional study was conducted during 1-30 May 2022. Systematic random sampling was used to obtain 352 samples. QOL was measured using the WHO Quality of Life Brief. The gathered information was coded, entered into EpiData 4.6.0.2 and analyzed with SPSS version 26. Multiple linear regression analysis was used to identify the correlates of QOL and the strength of the correlation was measured by β coefficient with 95% CI. The mean score of the overall QOL was 62.61 with a SD of 5.17. The mean (±SD) scores for the physical health, psychological, environmental and social relationship domains of primary caregivers were 57.36±9.98, 66.98±9.39, 66.06±12.91 and 60.02±9.14, respectively. Age was significantly associated with physical domain (β=-0.25, 95% CI -0.43 to -0.07) and with environmental domain (β=-4.57, 95% CI -9.06 to -0.09). Being divorced/widowed was negatively associated with psychological health (β=-2.99, 95% CI -5.82 to -0.17) and social health (β=-0.62, 95% CI -1.33 to -0.10). The presence of medical illness was negatively associated with the physical health domain (β=-4.32, 95% CI -7.64 to -2.91) and the environmental domain (β=-3.11, 95% CI -5.71 to -0.51). Poor social support was negatively associated with psychological health (β=-3.25, 95% CI -5.89 to -0.61) and the social health domain (β=-3.39, 95% CI -11.3 to 4.6), and moderate social support (β=8.62, 95% CI 3.15 to 14.09) was positively associated with physical health. Depression (β=-6.32, 95% CI -11.96 to -0.67) and anxiety (β =-3.07, 95% CI -5.80 to -0.34) were negatively associated with physical health and the psychological health domain, respectively. The findings from this study indicate that all dimensions of QOL of primary caregivers of children and adolescents with neurodevelopmental disorders in this study setting were compromised. Being divorced or widowed, lack of formal education, age, average monthly income, poor social support, depression, anxiety and the presence of medical illness were factors associated with QOL in all domains. This requires integrating a bio-psychosocial perspective, a positive mental health strategy and pharmaceutical therapies to enhance QOL for caregivers of children and adolescents with neurodevelopmental disorders.

Comparative Analysis of LORETA Z Score Neurofeedback and Cognitive Rehabilitation on Quality of Life and Response Inhibition in Individuals with Opioid Addiction.

Background. Previous studies has shown that conventional neurofeedback and cognitive rehabilitation can improve psychological outcomes in people with opioid use disorders. However, the effectiveness of LORETA Z-score neurofeedback (LZNFB) and attention bias modification training on quality of life and inhibitory control of these people has not been investigated yet. LZNFB targets deeper brain structures with higher precision, compared to conventional neurofeedback that typically focuses on surface EEG activity. The present study aims to compare the effect of these two methods on quality of life and response inhibition in men with opioid use disorders under methadone maintenance therapy (MMT). Methods. In this randomized controlled clinical trial with a pre-test, post-test, follow-up design, 30 men with opioid use disorders under MMT were randomly assigned into three groups of LZNFB, attention bias modification training, and control (MMT alone). The LZNFB and Cognitive Rehabilitation groups received 20 and 15 sessions of treatment, respectively. The Persian versions WHO Quality of Life-BREEF questionnaire and the Go/No-Go test were completed by the participants before, immediately after, and one month after interventions. The collected data were analyzed in SPSS v.22 software. Results. Both intervention groups showed a significant improvement in quality-of-life score and a significant reduction in response time at the post-test phase (P < .05), where LZNFB group showed more improvement in quality of life and more reduction in response inhibition. After one month, the increase in quality of life continued in both groups, while the decrease in response time continued only in the LZNFB group. Conclusion. Both LZNFB and attention bias modification training are effective in improving quality of life and response inhibition of men with OUD under MMT, however, LZNFB is more effective.

Effectiveness of a nurse-led family empowerment program to improve the quality of life among pregnant adolescents: A randomized controlled trial.

The present study examined the effects of a nurse-led family empowerment program on the quality of life of Palestinian pregnant adolescents. This was a randomized controlled trial with a two-group pre-/post-test design. The sample consisted of 58 pregnant adolescents recruited from six governmental primary health care clinics in Palestine. Participants were randomly allocated in equal numbers to either the control group (n = 29), which received routine care, or the experimental group (n = 29), which received both routine care and the study program. Data collection instruments included a demographic form and the WHO Quality of Life-BREF (WHOQoL-BREF). Data were collected twice: at 32 or 33 weeks' gestation to establish a baseline and at 36 or 37 weeks' gestation post-test. Statistical analyses were performed and included descriptive statistics, chi-square and t-tests. The study findings indicated a significant increase in the mean quality of life scores of the experimental group in the post-testcompared to the pre-test (P < 0.001). Additionally, pregnant adolescents in the experimental group demonstrated significantly higher post-test QoL scores than those in the control group (P < 0.001). The nurse-led family empowerment program emerges as a viable and efficacious alternative intervention for improving the quality of life among Palestinian pregnant adolescents. The study was registered with the NIH U.S. National Library of Medicine ClinicalTrials.gov on 01/09/2021 with the registration code NCT05031130. It can be accessed via this link: https://classic. gov/ct2/show/NCT05031130.