Quality Of Life Assessment Scale Research Articles

Evaluation of factors influencing the quality of life of residents living close to Northwest Solid Waste Treatment Complex Cu Chi districts, Ho Chi Minh City

Ho Chi Minh City (HCMC) grapples with a significant surge in waste generation, a consequence of urban expansion and development. The escalating waste poses a threat to the well-being of residents, particularly those in proximity to waste treatment facilities. This study delves into the impact of the Northwest Solid Waste Treatment Complex (NSWTC), a key waste treatment facility in HCMC, on residents residing in its immediate vicinity. The assessment encompasses 120 subjects living within a semi-permanent radius of 5 km from NSWTC. The residents’ Quality of Life (QoL) is quantitatively evaluated using the WHO QoL assessment scale (WHOQOL-BREF), comprising 26 survey questions categorized into four domains: living environment, physical health, psychological well-being, and socio-economic conditions. The identification of these domains is facilitated through bivariate and multivariate logistic analyses. Utilizing SPSS 20.0 software for data analysis, the findings reveal that a noteworthy 76.7% of subjects exhibit a subpar QoL. The overall QoL score, averaging 49.08 ± 18.82, falls considerably below acceptable standards, attributing this decline to environmental factors such as odours, dust, falling waste, water quality, and socio-economic conditions.

Efficacy of Lenvatinib in Combination With PD-1 Monoclonal Antibody and Interventional Treatment for Intermediate-Stage Hepatocellular Carcinoma: Impact on Serum Vascular Endothelial Growth Factor and Matrix Metalloproteinase-9 Levels: A Retrospective Study.

Objectives: To scrutinize the therapeutic efficiency and safety profile of lenvatinib, accompanied by the programmed cell death protein-1 (PD-1) monoclonal antibody, and interventional treatment in managing intermediate-stage hepatocellular carcinoma. Methods: Retrospective analysis was performed on clinical data from 93 patients suffering from intermediate to advanced hepatocellular carcinoma, treated at our institution from May 2018 to April 2020. Patients were divided based on the therapeutic regimen: 43 cases constituted the control group receiving lenvatinib plus transhepatic artery chemoembolization (TACE), while the remaining 50 cases in the study group were managed with lenvatinib, PD-1 monoclonal antibody, and TACE. Outcome measures included therapeutic efficacy, tumor markers (carcinoembryonic antigen [CEA], alpha-fetoprotein [AFP], α-L-fucosidase [AFU], carbohydrate antigen 199 [CA199]), immune response indices (CD3+, CD4+, CD8+, CD4+/CD8+ ratio), pertinent cytokine levels (vascular endothelial growth factor [VEGF], matrix metalloproteinase-9 [MMP-9], basic fibroblast growth factor [aFGF], acidic fibroblast growth factor [bFGF]), quality of life (as per Quality of Life Assessment Scale for Cancer Patients [QOL-LC] scores), adverse effects, and survival rates. Results: The study group exhibited a significantly enhanced total effective rate compared to the control group (74.00% vs 53.49%, P < .05). Post-treatment levels of CEA, AFP, AFU, CA199, CD8+, VEGF, MMP-9, aFGF, and bFGF were notably lower in both groups, particularly in the study group. Contrastingly, CD3+, CD4+, CD4+/CD8+ratios, and QOL-LC scores were substantially elevated in the study group (P < .05). Adverse reaction prevalence was analogous between 2 groups (27.91% vs 26.00%; P > .05). Moreover, the study group reported significantly higher 1-, 2-, and 3-year survival rates than the control group (P < .05). Conclusion: The combined use of lenvatinib, PD-1 monoclonal antibody, and interventional treatment for intermediate to advanced hepatocellular carcinoma may have a definitive therapeutic efficacy. This regimen is effective in reducing tumor marker levels, enhancing immune function, modulating VEGF, MMP-9, and other related cytokine levels, and improving patients' quality of life without significantly augmenting adverse effects. This treatment paradigm also contributes to increased survival rates and promises favorable prognosis.

Modified Acceptance and Commitment Psychotherapy in Complex Treatment of Comorbidity of Post-traumatic Stress Disorder and Mild Traumatic Brain Injury

The objective: approbation of the effectiveness of modified Acceptance and Commitment Therapy in a complex treatment of patients with comorbidity of posttraumatic stress disorder (PTSD) and mild traumatic brain injury (mTBI). Materials and methods. 329 veterans from three clinical groups: individuals with PTSD (n=109), with mild TBI (n=112) and with comorbid PTSD + TBI (n=108), underwent a course of combined therapy lasting 8 weeks: in addition to standard therapy, they received psychotherapeutic intervention (psychoeducation with elements of motivational interviewing and acceptance and commitment therapy for PTSD) and transcranial direct current stimulation (tDCS). The evaluation of the effectiveness of the treatment, in addition to a comprehensive psychodiagnostic examination before and after the therapy, included the Quality of Life Assessment Scale (O. Chaban). Results. Based on the obtained data, we can assume that representatives of the PTSD group, who initially evaluated the quality of social aspects of their lives more negatively, after the therapy looked more positively at the emotionally colored spheres of life (sex and mood). At the same time, after the therapy, the feeling of satisfaction with life was more positively assessed by those patients who were more satisfied with their life conditions before the therapy, and a higher assessment of the quality of life after the therapy was observed in those patients who, even before the therapy, had a higher level of satisfaction with your sex life. Summarizing the obtained data, it can be asserted that as a result of the therapy, the best results in the direction of increasing self-esteem of the quality of life were achieved precisely in relation to patients with PTSD/TBI. Conclusions. Complex treatment of patients with comorbid PTSD and TBI using modified acceptance and Acceptance and Commitment Therapy in combination of standard treatment and tDCS is a promising individual treatment methodology in this patient population.

Sensorimotor Rehabilitation and Psychotherapeutic Techniques Effect on the Psychoemotional State in the Stroke Recovery Period

INTRODUCTION. Stroke is the leading cause of disability of the population. In addition to motor disorders, cognitive and affective disorders contribute to the development of disability. The development of effective neurorehabilitation programs aimed not only at reducing the severity of motor deficits, but also at timely correction of psychoemotional disorders in stroke patients is very relevant for restorative medicine. In view of the proven positive therapeutic effect of physical exercises on anxiety and depression, their protective effect on cognitive functions, it is of interest to study the effect of motor rehabilitation on psychoemotional disorders in stroke patients.&#x0D; AIM. To study the effect of sensorimotor rehabilitation on affective and cognitive disorders in patients in the recovery period of stroke in comparison with a complex psychotherapeutic technique.&#x0D; MATERIALS AND METHODS. The study examined 2 groups of patients in the recovery period of ischemic stroke (up to 2 years) with the presence of anxiety and/or depressive disorders, comparable in gender, age, duration and focus of stroke localization, severity of neurological deficit. The 1st group — 24 patients — received a course of sensorimotor rehabilitation without targeted impact on affective disorders; the 2nd group — 25 patients — a course of complex medical and psychological adaptation lasting 18 days. The effectiveness of rehabilitation was assessed using validated scales and questionnaires (Rivermead Mobility Index, 6-point muscle strength assessment scale, modified Ashfort spasticity scale; Berg balance scales, Beck depression, Spielberger-Khanin anxiety, MMSE, MoCA; Schulte Table Methodology, SS-QOL Stroke Quality of Life Assessment Scale). Statistical analysis was carried out using the StatTech v. 2.8.8 program (developed by Stattech LLC, Russia).&#x0D; RESULTS AND DISCUSSION. The preliminary assessment carried out in both groups showed a twofold predominance of anxiety states over depressive ones, concomitant cognitive impairments were detected in 88 % of patients, among whom attention disorders were most often recorded (there was no intergroup difference in these indicators). After completing the course of both sensorimotor and medico-psychological rehabilitation, both groups showed a significant decrease in the level of situational and personal anxiety on the Spielberger-Khanin scale, positive dynamics on the MoСа scale, the SS-QOL questionnaire, while a significant decrease in the level of depression on the Beck scale was registered only in patients of the 2nd group on against the background of the use of specialized psychotherapeutic techniques.&#x0D; CONCLUSION. Motor rehabilitation is positively comparable with complex medical and psychological adaptation, it affects anxiety and cognitive functions in patients with ischemic stroke, it can be considered as one of the effective ways to correct anxiety states and prevent cognitive impairment in these patients, while in the treatment of depression the priority is should be given to specialized medical and psychological intervention.

Digital Biomarkers in the Assessment of Mobility in Individuals with Multiple Sclerosis

The aim of this study was to investigate signal patterns and parameters of digital biomarkers in the assessment of mobility in individuals with multiple sclerosis, captured through motion sensors. This is an integrative literature review based on the PRISMA recommendations, which included studies that used wearable technology, such as accelerometers, wearable sensors or inertial sensors, and analyzed mobility/gait-related parameters, such as speed, step count, rhythm, balance, duration and intensity of activity. A total of 1602 studies were identified, of which only 21 were included in the final qualitative synthesis. The main digital biomarkers identified presented signal patterns and parameters captured through different wearable devices, including triaxial accelerometers, inertial sensors, smartphones or smartwatches. The studies employed different objective biomarker reference measures, such as walking speed and step count, and subjective biomarker reference measures, such as fatigue and quality of life assessment scales, for a comprehensive assessment of the participants’ health and mobility. It was found that digital biomarkers play a fundamental role in any individual’s health assessment and protocols. However, it is essential to understand these signals and standardize the choice of the best method to capture signals of high quantity and quality, especially for individuals affected by some neurological pathology.

Integrating visual communication technology with film communication on the mental health of depression patients

Background Depression is a type of mental disorder, and patients with it often exhibit symptoms such as low mood, delayed thinking, and fatigue. With the development of society, the incidence rate of depression is also gradually increasing, however, the pathogenesis of the disease has not yet been clear.Subjects and MethodsTo analyze the impact of integrating visual communication technology from the perspective of film communication on the mental health of depression patients, 100 depression patients were selected and randomly divided into two groups: the research group and the control group, with 50 patients in each group. Both groups used medication for basic treatment. In addition, patients in the control group underwent regular movie viewing twice a week. The patients in the research group underwent movie viewing that incorporates visual communication technology twice a week. The treatment period for both groups of patients was 4 weeks. The analysis tools used in the study include the Hamilton Depression Scale, Hamilton Anxiety Scale, Comprehensive Quality of Life Assessment Scale, and SPSS23.0.Results The results showed that after treatment, the depression and anxiety scores of the study group patients showed a significant decrease (P&lt;0.05), and there was a significant difference compared to the pre-treatment scores. In addition, the physical health, mental health, and social function scores of the study group patients showed a significant increase (P&lt;0.05), and there was a significant difference compared to the pre-treatment scores.ConclusionsThe integration of visual communication technology from the perspective of film communication is beneficial for the mental health of patients with depression.

A comparative study of Chinese medicine quality of life assessment scale (CQ-11D) and EQ-5D-5L and SF-6D scales based on Chinese population

PurposeTo measure health-related quality of life in the Chinese population using three universal health utility scales (CQ-11D, EQ-5D-5L, and SF-6D) and to compare the differences in the results obtained by the different scales to provide a reference for future utility on health-related quality of life in the Chinese population.MethodsAccording to the Chinese population's distribution area, gender, and age, quota sampling was conducted. Three scales, CQ-11D, EQ-5D-5L, and SF-6D, whose results were self-reported, were collected in succession after collecting respondents' demographic information. The health utility value and floor/ceiling effect were explained. Bland–Altman was used to evaluate the consistency, the intraclass correlation coefficient was used to evaluate the correlation, and the receiver operating characteristic curve was used to evaluate the discriminative validity of the scale.ResultsThe mean utility values of the CQ-11D, EQ-5D-5L, and SF-6D scales, respectively, were 0.891, 0.927, and 0.841. The floor effect did not appear in any of the three scales, but the ceiling effect did, and the EQ-5D-5L ceiling effect was the most severe. The limits of the agreement interval for CQ-11D versus EQ-5D-5L in the total sample population were (-0.245,0.172); for CQ-11D versus SF-6D, they were (− 0.256,0.354); and for EQ-5D-5L versus SF-6D, they were (-0.199,0.371). The consistency of the three scales is satisfactory overall. In the total population, the intraclass correlation coefficient between CQ-11D and EQ-5D-5L was 0.709, while EQ-5D-5L and SF-6D were 0.0.565 and that between EQ-5D-5L and SF-6D was 0.472. According to the subject operation curve results, the area under the curve for the total sample population of CQ-11D was 0.746, EQ-5D-5L was 0.669, and SF-6D was 0.734.ConclusionThe CQ-11D is inferior to the EQ-5D-5L, but superior to the SF-6D. There is a strong correlation between the health utility values of the total population as measured by the three scales and those of the healthy population. The CQ-11D scale is the most sensitive to differences between populations and diseases.

Psycho-emotional status in patients with endometriosis-associated pain syndrome in various disease phenotypes

BACKGROUND: Patients with endometriosis-associated pain syndrome in combination with anxiety or depression have lower treatment effectiveness and satisfaction with both the disease itself and the pain syndrome compared to patients with pain syndrome but without depression or anxiety.&#x0D; AIM: The aim of the study is to assess the relationship between psychosocial status and endometriosis-associated pain syndrome in patients with different phenotypes of endometriosis using pain assessment scales, psychosocial state assessment scales, and quality of life assessment scales.&#x0D; MATERIALS AND METHODS: We examined 81 patients using a number of questionnaires: Visual Analogue Scale, Numeric Rating Scale, Hospital Anxiety and Depression Scale, Beck Depression Scale, Spielberger State-Trait Anxiety Inventory, and Short Form-36 quality of life assessment. The patients were divided into three groups: isolated adenomyosis (n = 39), adenomyosis combined with external genital endometriosis (n = 21), and the control group (n = 21).&#x0D; RESULTS: Our study has shown that patients with adenomyosis combined with external genital endometriosis had the highest scores on all questionnaires for assessing anxiety and depression, as well as a low quality of life in general, which significantly differed from those in the control group (p 0.05). The results in the group of women with isolated adenomyosis are not so unambiguous and, overall, somewhat better than in the group of patients with adenomyosis combined with external genital endometriosis, but significantly worse compared to the control group. When assessing the severity of dysmenorrhea, higher scores were also found in the group of women with adenomyosis combined with external genital endometriosis: 6.64 2.11 cm (Visual Analogue Scale) and 6.9 2.05 cm (Numeric Rating Scale), while in the group of women with isolated adenomyosis, the scores were 5.29 1.9 cm and 5.83 1.72 cm, respectively (p = 0.028). Women in the control group had no pain syndrome.&#x0D; CONCLUSIONS: Poor mental and physical health scores obtained in this study in women with external genital endometriosis dictate the need for an objective and multicomponent assessment of the psycho-emotional status in patients, followed by complex treatment and team management with related specialists.

Первинний хронічний біль як соматизація дистресу

Relevance. The direct functional significance of pain is to signal the action of a stimulus, damage to the integrity of the organism or its individual structures. A number of scientists have approached the study of pain as a physiological defense mechanism, during which we understand the principles of its emergence, course, localization, and ways to overcome pain sensations through pharmacological, physical, and instrumental methods. However, the problem of pain arises when the physiological substrate is absent or does not correspond to the strength or duration of the manifestation. This is where we can talk about pain of a psychogenic nature, which despite a number of studies that are currently underway, still remains difficult to treat. Objective. To improve the effectiveness of medical-psychological assistance by studying the nature and patterns of pain syndrome in patients with primary chronic pain with subsequent psycho-correction and the use of psychotherapeutic interventions. Methods. The study design was a monocentric randomized controlled trial with parallel groups. The study involved 14 individuals with primary chronic pain syndrome, which corresponded to ethical and deontological norms according to the principles set out in the Helsinki Declaration. The tools used in the study included the SPAASMS subjective pain assessment scale, the somatic symptoms questionnaire (SSS-8), the Bass-Darky aggressiveness and hostility level questionnaire (BDHI), as well as the Chaban O.S. quality of life assessment scale (CQLS). Results. At the completion of the study, a statistically significant difference was observed for all clinical parameters between the experimental and control groups. Comparison of the values of the scale in the experimental group on days 1 and 42 demonstrated statistically significant changes in all four indicators. However, this study reveals a limited sample, which in turn allows for expanding the sample size and investigating the phenomenon of applied interventions in future pilot studies, as the primary results provide a qualitative and positive trend in reducing the effects and impact of primary chronic pain, as well as improving the quality of life indicator. Conclusions. The results of this study confirm the effectiveness of psychological interventions, as well as psychological interventions for reducing the subjective sensation of pain syndrome, symptoms of somatization, aggressive and hostile reactions, and improving the quality of life in individuals suffering from primary chronic pain.

The development of a Cancer Pain Belief Modification Program for patients with oral cancer in China: a feasibility study

BackgroundAcceptance-based pain management interventions have been receiving growing attention in cancer pain care. This study aimed to develop a cancer pain management program based on belief modification to improve the cancer pain experience of Chinese oral cancer survivors and to explore the acceptability and preliminary outcomes of the Cancer Pain Belief Modification Program (CPBMP).MethodsA mixed-methods approach was applied to develop and revise the program. The CPBMP was developed and revised using the Delphi technique, and its further improvement was explored with a one-group pre- and post-trial designed with a sample of 16 Chinese oral cancer survivors, and semi-structured interviews. Research instruments included Numeric Rating Scale (NRS), Chinese version of Illness Perception Questionnaire-Revised for Cancer Pain (IPQ-CaCP), and the University of Washington Quality of Life assessment scale (UW-QOL). Descriptive statistics, t-test, and Mann–Whitney U test were used to analyse the data. The semi-structured questions were analysed using content analysis.ResultsThe six-module CPBMP was endorsed by most experts and patients. The expert authority coefficient value was 0.75 in the first round of the Delphi survey and 0.78 in the second round. The “pain intense”, “negative pain beliefs” scores of pre- and post-testing decreased from 5.63 ± 0.48 to 0.81 ± 0.54 (t = -3.746, p < 0.001); from 140.63 ± 9.02 to 52.75 ± 7.27 (Z = 12.406, p < 0.001); and the “positive pain beliefs”, “quality of life” scores increased from 55.13 ± 4.54 to 66.00 ± 4.70 (Z = -6.983, p < 0.001); from 66.97 ± 15.01 to 86.69 ± 8.42 (Z = 7.283, p < 0.001). The qualitative data also indicated that CPBMP was well acceptable.ConclusionOur study showed the acceptability and preliminary outcomes of CPBMP patients. CPBMP improves the pain experience of Chinese oral cancer patients and provides a reference for cancer pain management in the future.Trial registrationThe feasibility study has already been registered on the Chinese Clinical Trial Registry (ChiCTR) (www.chictr.org.cn) in 11/09/2021. (ChiCTR2100051065).

The association of family functions in families of children who undergo organ transplantation: the quality of life of the children and their families

Aim: Family functioning and quality of life are related. This study was to examine the association of family functioning in families of children/adolescents who had undergone organ transplantation and the quality of life of these children/adolescents and their parents. Methods: This descriptive cross-sectional study collected research data using the following tools: Child Information Form, Parent Information Form, Pediatric Quality of Life Questionnaire, Parent Quality of Life Assessment Scale, and Family Assessment Device. Results: This study found that the quality of life mean scores of children and parents were low. There was a positive relationship between the general quality of life of children who underwent organ transplantation and their psychosocial quality of life and the quality of life of their parents. This study also found a negative relationship between the psychosocial quality of life of children who had undergone organ transplantation and the subdimensions of roles, affective responsiveness, behavioral control, and general family functioning. Conclusion: This study showed that the quality of life levels of children who have undergone organ transplantation and of their parents may be low and may be associated to each other, which may lead family functioning to be negative.

Досвід використання арипіпразолу у комплексному лікуванні ПТСР внаслідок війни в Україні

Досвід використання арипіпразолу у комплексному лікуванні ПТСР внаслідок війни в Україні

Clinical and laboratory phenotype of postcovid asthenic syndrome in children of primary school age

Objective. To determine the clinical and laboratory features of the postcovid syndrome in children of primary school age.&#x0D; Materials and methods. The analysis of complaints and anamnesis, somatic and neurological status in 24 children who had a new coronavirus infection was carried out; the results were also analyzed according to the Subjective Asthenia Scale (version for parents), the Quality of Life Assessment Scale (version for children), the Waynes questionnaire and scheme, the functional status scale. The concentration of monocytic chemotactic factor in the saliva was determined using enzyme immunoassay.&#x0D; Results. Most of the children presented astheno-vegetative complaints, which were confirmed by the MFS scores, and the Wayne's questionnaire and scheme. The concentration of monocytic chemotactic protein in the examined cohort of children was 32.48 23.22 pg/ml, with no significant difference by sex. The level of physical functioning by the quality of life scale was significantly higher in boys (100.00 0.00 points) than in girls (82.03 15.46 points, p = 0.02). A correlation was obtained between the salivary monocyte chemotactic protein content and the scores obtained using the Wayne questionnaire and scheme, as well as the MFS and functional status scales.&#x0D; Conclusions. Vegetative and asthenic syndromes are closely related to the concentration of salivary monocyte chemotactic factor.

Quality of life of pediatric patients with atopic dermatitis and their caregivers.

To compare the quality of life (QoL) of children with and without atopic dermatitis (AD) and that of their caregivers and to assess their QoL according to different degrees of AD. This is a cross-sectional, case-control study conducted with patients aged between 4 and 12years with and without AD and their caregivers. Patients were treated at the Pediatric Dermatology Outpatient Center and the Childcare Center of the Joana de Gusmão Children's Hospital, respectively, from June 2021 to March 2022. The QoL Assessment Scale Autoquestionnaire Qualité de Vie Infant Imagé (AUQEI) was applied to children and adolescents with AD and the control group while the World Health Organization Quality of Life assessment instrument was administered to their caregivers. Fifty cases and fifty controls were included in this study. When assessing the QoL of the case and control groups, statistically significant differences were found in the domains of the AUQUEI instrument. Regarding QoL and AD severity, a statistically significant difference was seen (p = 0.027) when comparing moderate and severe SCORAD scores. When comparing the QoL of children with and without AD, a difference was seen between the two groups. The QoL of AD patients was worse and related to the severity of the disease. A better QoL was found among the caregivers in the control group. In the case group, the higher the SCORAD score, the worse the QoL. No relationship was found between AD severity and the QoL of the caregivers in the case group.

Development and Validation of Nocturia-Related Quality of Life Assessment Scale among Adults

Abstract Background Nocturia has high impact on quality of life (QoL) based on varying geographical and cultural factors. Speculating this, nocturia-related QoL (NRQoL) assessment scale was developed precisely, appropriate to the Indian context. Objective The current study aimed to develop and validate an NRQoL assessment scale for Indian adults. Methods An exploratory descriptive design was performed among 420 cases and 206 controls aged 35 to 65 years from two selected tertiary hospitals in Mangaluru, Karnataka, India. The NRQoL assessment scale was formulated through the following phases: review of literature, evaluation by experts, and pretesting. Exploratory factor analysis (EFA) was performed to reduce the number of items and to define domains. Reliability, construct validity, discriminant validity, and convergent validity of the scale were calculated. Results EFA resulted in the removal of seven items from a 36-item instrument, resulting NRQoL assessment scale into six domains as follows: (1) functional, (2) sleep, (3) emotional, (4) physical, (5) social and family, and (6) spiritual. The findings from the tertiary hospitals study confirmed that the scale was valid and reliable to measure NRQoL among adults. Conclusion The NRQoL assessment scale is a new, valid, and reliable instrument that is well-understood by adults and can be answered quickly. It is a useful new tool that can be translated and tested in other cultures and languages.

Personality and psychopathological profile of patients and botulinum therapy for blepharospasm

Background. Blepharospasm (BS) includes non-motor symptoms manifested by psychopathological disorders. The impact of these disorders on patients' quality of life and therapy of motor symptoms with botulinum toxin is poorly understood.&#x0D; Aim. To analyze the correlation of different characterological personality abnormalities (CPA) with the BS severity and the response to botulinum toxin therapy (BT).&#x0D; Materials and methods. Forty-six BS patients (29 females, 17 males) aged 30 to 85 years (6111.5) with BS were examined. The control group included 46 healthy individuals (39 females and 7 males, with a mean age of 56.49.67). Patients were examined before and after BT (after 12 months) using the BS severity scale (BSDI), EQ-5D (EQ-5D-3L) quality of life assessment scales, General Anxiety Disorder (GAD-7) scale, Brief Fear of Negative Evaluation Scale (BFNE-S), and SCID-II-PD structured personality questionnaire.&#x0D; Results. In the BS group of patients, unemployed and non-married were more common (p0.05) than in healthy individuals. In the BS patient group, there was an increase in anxiety (15.525.6 vs 4.283.5 control group by GAD-7 scale) and fear of negative evaluation (42.449.2 in the main group vs 21.347.3 in the control group). Quality of life was lower in BS patients (65.43, median 62 vs 88.2, median 92, p0.05). The prevalence of cluster C CPA (anxiety disorders) in patients with BS and, in particular, the obsessive-compulsive disorder was revealed. Patients with different personality profiles showed no differences in the BS severity before BT. The BT efficacy was higher in patients with cluster C CPA.&#x0D; Conclusion. BS patients often have anxious type CPA; in these patients, BT is more effective than in other CPAs.

Quality of life among adolescents with idiopathic scoliosis in Tunisia.

our study aimed to assess the quality of life (QOL) among adolescents with adolescent idiopathic scoliosis (AIS) receiving nonoperative treatment, and to identify the demographic and clinical factors associated with poor QOL. this is a cross-sectional study. We included adolescents followed in the Department of Physical Medicine and Rehabilitation at Taher Sfar Hospital (Mahdia - Tunisia). The Quality-of-Life Profile for Spine Deformities (QLPSD), the Scoliosis Research Society 22 questionnaire (SRS-22) and the visual analogue scale objectifying the QOL (EVA QOL) were used. Correlations between the QOL domains and selected characteristics were performed. a total of 48 adolescents with AIS were included, with a mean age of 14.2 ± 2.1 years and a sex ratio (M/F) of 0.77. Adolescents who underwent rehabilitation treatment only had significantly better quality of life (QOL) scores than those with braces, as measured by three scales. Among brace wearers, we found a correlation between QOL and the degree of correction achieved by the brace, as measured by the EVA-QOL. We observed significant relationships between psychosocial status and age, correction angle, and treatment duration among braced patients, as measured by the QLPSD. Additionally, we found that dorsal flexibility was correlated with the correction angle and the treatment duration. According to the SRS-22, the overall QOL score of braced adolescents was significantly correlated with the correction obtained by the brace. wearing a brace in adolescent with AIS leads to a significant decrease in QOL according to the three QOL assessment scales.

A double-blind controlled clinical trial to evaluate the effects of nasal therapy with Vrihatajivakadya oil on different viscosities in patients with migraine

BackgroundMigraine, characterized by pain of a specific type in one half of the head has a close resemblance with Ardhavabhedaka described in Ayurveda. Nasya karma (nasal therapy) with Vrihatajivakadya oil is indicated in Ardhavabhedaka. Low viscosity oil (LVO) and medium viscosity oil (MVO) prepared by Snehapaka (a specific Ayurveda method for preparation of oil) are advocated in different classical Ayurveda texts for N.karma. The objectivesThis study was done to assess the effects of Vrihatajivakadhya oil on different viscosities in N.karma for the better Ayurveda management of migraine. Material and methodsIn this double-blind randomized controlled trial a total of 90 patients were randomly divided into two groups for N.karma with oil of different viscosities. In the group treated with LVO, 44 patients completed their treatment and one patient was lost in follow-up. In another group treated with MVO, 45 patients were enrolled and completed the intervention. N.karma was done with this oil in the dose of 6 drops per nostril for the duration of 14 days for each participant. The follow-up was done on the 15th day and 45th days. The assessment was done by the Migraine Disability Assessment Score (MIDAS) and Migraine Specific Quality of Life Assessment scale. ResultDuring the trial, significant improvement in both the groups on both parameters was observed. No adverse event was noticed during the study. ConclusionN.karma with MVO had better improvement. No adverse event was noticed during the study. N.karma with these oils is effective and safe for migraine.

The choice of tactics of rehabilitation measures in patients with chronic paraproctitis, depending on the volume of surgical intervention based on quality of life indicators

BACKGROUND: The development of medical technologies puts forward requirements for the improvement and optimization of treatment and rehabilitation algorithms for providing surgical care to proctological patients and, in particular, patients with chronic paraproctitis. The criteria for the effectiveness of therapy are the period of wound healing, the frequency of recurrence of the disease and the preservation of the function of the anal sphincter. The development of minimally invasive surgical technologies is a new promising area of outpatient coloproctology.&#x0D; AIMS: was to evaluate the effectiveness of the use of physiotherapy programs for postoperative rehabilitation according to the SF-36 quality of life assessment scale in groups of patients operated on by various methods of surgical interventions and to develop an Algorithm for surgical treatment and postoperative rehabilitation of patients with chronic paraproctitis.&#x0D; MATERIAL AND METHODS: The study included observation and control in the pre- and early postoperative period for 270 operated patients with extra- and transsphincter pararectal fistulas with various options for surgical treatment and rehabilitation programs used in the early postoperative period. As a criterion of effectiveness, an assessment of the quality of life b according to the SF-36 questionnaire was used. The surgical-physiotherapeutic Algorithm of surgical treatment and rehabilitation of patients with chronic paraproctitis is proposed for wide introduction into clinical practice.&#x0D; RESULTS: As a result of the analysis of the data obtained, it was found that the quality of life depends on the type of operation: the advantage of using minimally invasive surgical interventions and the rehabilitation program used has been proven: the advantage of using an extended 4-component rehabilitation program has been proven.&#x0D; CONCLUSION: The data obtained made it possible to determine the tactics of rehabilitation measures in patients with chronic paraproctitis depending on the volume of surgical intervention and display it in a visual, schematic form ― Algorithm for surgical treatment and rehabilitation of patients with chronic paraproctitis.

Quality of life and influencing factors of postoperative accelerated rehabilitation of esophageal cancer patients

Objective: To explore the quality of life and its influencing factors of enhanced recovery after surgery (ERAS) of esophageal cancer patients. Methods: The quality of life of 134 esophageal cancer patients was assessed using the quality of life assessment scale (EORTC QLQ-C30) developed by the European Cancer Research and Treatment Organization. Student's t test, One-way ANOVA and multiple linear regression statistical methods were used to analyze the effects of sociodemographic and clinical characteristics on patients' quality of life. Results: The overall score of quality of life (74.00) was lower than that of the general population (75.30). However, the scores of emotion and cognition in function dimension (93.97 and 95.77) were better than those of the general population (82.80 and 86.50). The results of fatigue, pain, insomnia and constipation in symptom dimension (14.18, 10.94, 11.69 and 5.72) were better than those of the general population (28.80, 20.50, 20.40 and 10.70). The pathological stage, body mass index and dietary were independent influencing factors for the quality of life of patients with esophageal cancer (P<0.05). Conclusions: ERAS can partially improve the quality of life of esophageal cancer patients. More attention should be paid to the esophageal cancer patients after surgery and take targeted measures to improve their quality of life.