The spectrum of the second harmonic signal generated in quadratic nonlinear photonic crystals, having different types of edge dislocations, was studied theoretically and experimentally. In the case of a dislocation with a fractional topological charge, we observed an asymmetric spectral conversion efficiency response, where the degree of asymmetry depends on the value of the fractional charge. Moreover, we have found that the conversion efficiency spectrum exhibits a periodic dependence on the topological charge value. In addition, nonlinear photonic crystals with multiple edge dislocations were studied. We show that for any number of dislocations characterized by even topological charge, the nonlinear spectral response will be identical to the response of the ideal, dislocation-free structure. This is a generalization of a previous observation that was made for crystals with a single even charge dislocation. Furthermore, for any number of dislocations with odd topological charge, two new peaks of maximal efficiency are observed in the second harmonic spectrum, in addition to a series of local efficiency peaks that are governed by the total number of dislocations. This is also a generalization of a previous observation that was made for a single dislocation case having an odd topological charge.