Longstanding puzzles in spin physics can be confronted at the high energies of the LHC. Heavy quarks will be produced with significant polarization, both as single spin asymmetries and through polarization correlations. Lower energy proton accelerator and leptoproduction data suggest various mechanisms within QCD for polarization phenomena that can be tested at higher energies. Observation of strange and charm hadron polarization reveals important aspects of QCD spin physics. Top quark polarization is predicted to be significant, and polarization correlations will reveal important aspects of the gluon distributions of the hadrons.