Frost formation and defrosting water retention directly affect the heat transfer process of outdoor finned tube heat exchanger, which in turn influences the energy efficiency of air source heat pumps for building heating. Three typical wettability surfaces were prepared, including a bare copper hydrophilic surface (BCS), a hydrophobic copper surface (HCS) and a superhydrophobic copper surface (SHCS). The above three surfaces are combined in pairs to construct three different wettability combinations, which are Combination 1: HCS-BCS, Combination 2: BCS-SHCS and Combination 3: HCS-SHCS, respectively. Frosting-defrosting experiments between vertical double surfaces are carried out on the above combinations. The results illustrated that the combinations with SHCS exhibit excellent frost inhibition properties. Compared with Combination 1, the channel filling rate of Combination 2 and Combination 3 were reduced by 16.79 % and 30.09 % respectively at a frosting time of 60 min. The defrosting time of the combination is determined by the slower defrosting of the two surfaces. Compared with Combination 2, the defrosting rate of Combination 3 is improved by up to about 12.93 %. Avoiding the formation of large-sized liquid films and droplets or utilizing the “absorption” phenomenon caused by wettability differences between surfaces are important measures to reduce the possibility of bridge formation during the defrosting process. And the greater the wettability difference, the more obvious the “absorption” phenomenon became. Spherical droplets on the SHCS can be completely absorbed by the liquid film on BCS under the action of differential surface tension. Neither Combination 2 nor Combination 3 formed a liquid bridge at a surface spacing of 2 mm. The research will provide theoretical support for the selection of fin spacing and fin coating type under different working conditions in practical engineering.