Web Of Science For Publications Research Articles

Abstract PO1-01-04: The optimal neoadjuvant treatment regimen for HR+/HER2+ breast cancer: a network meta-analysis

Abstract Background In patients with the HR+/HER2+ breast cancer (BC) subtype, it can be more challenging to achieve pathological complete response (pCR) after neoadjuvant therapy compared with the HR-/HER2+ subtype. The importance of neoadjuvant therapy and the association of pCR with long-term clinical benefits have been widely demonstrated in HER2+ BC. This network meta-analysis aimed to identify the optimal anti-HER2 regimen, the role of endocrine therapy, and the better chemotherapy choice for the neoadjuvant treatment of HR+/HER2+ BC patients. Methods Literature for neoadjuvant clinical trials in HR+/HER2+ breast cancer was searched in Medline, EMBASE, Cochrane Library, and Web of Science for publications released before June 2023. Single-arm trials, retrospective studies, and observational studies were excluded, as well as studies containing no neoadjuvant phase and/or no anti-HER2 drugs. A network meta-analysis with the fixed-effect model in a Bayesian framework was performed. Odds ratios (ORs) with 95% confidence intervals (CI) for pathological complete response (pCR) analysis and hazard ratios (HRs) with 95% CI for event-free survival (EFS) were calculated. A ranking of treatment patterns was performed using SUCRA. (Registered in PROSPERO: CRD42023385644 Results 2,844 records were identified by the literature search, 60 trials were included after the screening, and valid data were extracted. 19 trials and 2,883 patients were included in the primary analysis of pCR. Compared with trastuzumab + chemotherapy (CT), three treatment regimens showed significantly higher pCR rates, T-DM1 based treatment (T-DM1, OR: 2.83, 95% CI: 1.90, 4.27; which includes T-DM1 alone, T-DM1 + pertuzumab or T-DM1 + endocrine therapy), trastuzumab + pertuzumab + CT (PH, OR: 2.57, 95% CI: 1.70, 3.94), and trastuzumab + tyrosine kinase inhibitor (TKI)+ CT (H+TKI, OR: 1.60, 95% CI: 1.22, 2.09; TKI includes lapatinib, neratinib and pyrotinib). The SUCRA ranking of pCR showed that T-DM1 was ranked first (SUCRA: 0.94), followed by PH (SUCRA: 0.85) and H+TKI (SUCRA: 0.60). PH came first in the SUCRA ranking of EFS (SUCRA: 0.74) as well as cumulative SUCRA combining pCR and EFS (SUCRA: 0.79). For chemotherapy strategies, platinum-containing regimens showed no significant increase in pCR rate compared to no platinum regimens (OR: 1.27, 95% CI: 0.95, 1.69), regimens with anthracycline also had no statistical difference from those without anthracycline (OR: 0.74, 95% CI: 0.51, 1.07). When assessing the impact of endocrine therapy, no significant difference in pCR rate was observed with or without endocrine therapy (OR: 1.18, 95% CI: 0.80, 1.73). Conclusions The PH regimen remains the best neoadjuvant treatment choice for HR+/HER2+ early BC patients considering pCR and EFS outcomes simultaneously. H+TKI did not show significant benefits, so it is not recommended to be given priority in clinical practice. The platinum-containing regimen’s potential benefit compared to the non-platinum regimen is uncertain and needs more clinical investigation. The necessity of adding endocrine therapy is not proven due to limited data availability. Funding: This study was sponsored by Shanghai Roche Pharmaceuticals Ltd. Disclosure: Hao Tang, Shanghai Roche Pharmaceuticals Ltd.: Employee (Ongoing), Salary (Ongoing) Yajing Feng, Shanghai Roche Pharmaceuticals Ltd.: Employee (Ongoing), Salary (Ongoing) Xin Yu, Shanghai Roche Pharmaceuticals Ltd.: Employee (Ongoing), Salary (Ongoing) Citation Format: Hao Wang, Shiwei Liu, Miao Yu, Kun Mi, Exian Mou, Li Xia, Weimin Xie, Hao Tang, Yajing Feng, Xin Yu. The optimal neoadjuvant treatment regimen for HR+/HER2+ breast cancer: a network meta-analysis [abstract]. In: Proceedings of the 2023 San Antonio Breast Cancer Symposium; 2023 Dec 5-9; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2024;84(9 Suppl):Abstract nr PO1-01-04.

Chatbots and ChatGPT: A Bibliometric Analysis and Systematic Review of Publications in Web of Science and Scopus Databases

Chatbots and ChatGPT: A Bibliometric Analysis and Systematic Review of Publications in Web of Science and Scopus Databases

Professional Ethics, Challenges and Opportunities for Blockchain Technology in Healthcare Sector: A Systematic Review

Background:: The healthcare sector faces numerous issues, such as insurance fraud, electronic medical record management, interoperability, insecure dissemination of information, etc. The novel Blockchain technology holds tremendous potential to transform the healthcare sector by addressing these rising challenges in the industry. It provides a secure platform for storing, disseminating, and retrieving sensitive patient data and health records while preserving the ethical principles of the healthcare sector. Method:: In this study, we systematically reviewed the literature on blockchain technology in healthcare using PRISMA and highlighted how blockchain technology might promote innovation and deliver major improvements in the healthcare sector. Result:: Our goal is to examine the present status of this discipline, focusing on limits and potential advances. Queries were used to gather Scopus, PubMed, SpringerLink, IEEE Xplore, and Web of Science publications that met the criteria for the selection of papers. Conclusion:: This article, thus, analyses the potential for blockchain in the healthcare industry and outlines blockchain-based products in healthcare. Our study enhances and complements prior healthcare blockchain research.

Behavioral finance: Evolution from the classical theory and remarks

AbstractBehavioral finance has emerged from the divergences observed to explain and address the traditional theories of finance and serves as supplement to classical finance by introducing behavioral aspects to decision‐making. This study provides academics with a comprehensible and complete synopsis of the evolution of behavioral finance, as well as critical insight is provided. The synopsis was based on the search for publications in Web of Science (WoS) and Scopus and the use of R, Gephi and Tree of Science ‐ToS‐ software, using citation analysis, graphos and classification analysis. The results showed psychological aspects, investment in stocks and cognitive biases with the highest visibility. A tree‐like structure of hierarchization was developed by ToS. The clusters of publications with the greatest literary contribution were analyzed and the publications with the greatest visibility in each cluster identified. This study provides insights into the current trend in finance towards better understanding of the essential factors in the investor´s decision making.

Determining the Characteristics of Papers That Garner the Most Significant Impact: A Deep Dive into Mexican Engineering Publications

Engineers make things, make things work, and make things work better and easier. This kind of knowledge is crucial for innovation, and much of the explicit knowledge developed by engineers is embodied in scientific publications. In this paper, we analyze the evolution of publications and citations in engineering in a middle-income country such as Mexico. Using a database of all Mexican publications in Web of Science from 2004 to 2017, we explore the characteristics of publications that tend to have the greatest impact; this is the highest number of citations. Among the variables studied are the type of collaboration (no collaboration, domestic, bilateral, or multilateral), the number of coauthors and countries, controlling for a coauthor from the USA, and the affiliation institution of the Mexican author(s). Our results emphasize the overall importance of joint international efforts and suggest that publications with the highest number of citations are those with multinational collaboration (coauthors from three or more countries) and when one of the coauthors is from the USA. Another interesting result is that single-authored papers have had a higher impact than those written through domestic collaboration.

Environmental valuation: a systematic review using bibliometrics

Environmental valuation has been applied since 1987. In this article, a bibliometric approach was employed between the years 1987 and 2022 using the Web of Science (WoS) and Scopus databases to examine the scientific production on this subject. The VOSviewer software was used, and a sample of 712 publications in WoS and 743 in Scopus was found. The highest number of publications in WoS was in 2018, while in Scopus it was in 2017. During the research period, the United States had the highest number of publications on environmental valuation in WoS, while the United Kingdom had the highest number in Scopus. The most frequently appearing keyword was "environmental valuation" in both platforms. The author with the highest number of publications was Nick Hanley from the University of Glasgow in Scotland, in both platforms. The topic of environmental valuation has gained importance over the years due to increased interest in the environment, as a response to the damages incurred. It aims to assist decision-making and enable the accounting of costs and benefits associated with natural capital.

The role of syphilis self-testing as an additional syphilis testing approach in key populations: a systematic review and meta-analysis

Syphilis is causing epidemics in many countries. Syphilis self-testing (SST) has potential to increase testing and treatment coverage in the same manner as documented for self-testing of, for example, HIV, hepatitis C virus, and COVID-19. We aimed to synthesise current evidence on the utility of SST. We conducted a systematic review and, where possible, meta-analysis. We searched MEDLINE, Embase, CINAHL, Scopus, and Web of Science for publications published from Jan 1, 2000, to Oct 13, 2022. We included publications with original data on any syphilis rapid tests, including dual HIV-syphilis tests. Study populations were not restricted. We used random-effects meta-analysis to calculate the pooled proportion of people offered SST who undertook the test. The systematic review was registered in PROSPERO (CRD42022302129). In total, 40 499 citations were identified. 11 publications from seven studies from the USA, Zimbabwe, and China met eligibility criteria. Of those, four studies reported data from men who have sex with men and five studies used dual HIV-SST. Using data from one randomised controlled trial and three observational studies, the pooled proportion of people who received SST kits who undertook the test was 88% (95% CI 85-91). No studies provided data on the sensitivity or specificity of SST. Overall, user and provider preference for SST was high, with participants reporting convenience, privacy, rapid results, autonomy, trust in blood-based tests, decreased facility contact, and time savings, with individuals being able to correctly self-test. Publications from China reported that SST had lower costs per person tested than existing facility-based testing options. Our review builds on the literature for self-testing across different disease areas and demonstrates that SST has the potential to reach underserved populations. As this review found that SST use was acceptable and feasible to implement, SST can be used as an additional syphilis testing approach. Since no data on the sensitivity and specificity of SST were found, further implementation research will be required to guide the best strategies for SST service delivery and future scale-up. WHO, Australian National Health and Medical Research Council, and Unitaid.

Dysregulation of the autonomic nervous system in adult attention deficit hyperactivity disorder. A systematic review

ABSTRACT Background: Adult Attention Deficit Hyperactivity Disorder (aADHD) is characterised by inattention, hyperactivity, impulsivity, and emotional instability, all of which were linked to altered modulation of the autonomic nervous system. This and the clinical effectiveness of sympathomimetic medication raised the question if autonomic modulation is altered in aADHD patients. Methods: We systematically searched PubMed, Cochrane Library, and Web Of Science for publications investigating autonomic modulation in aADHD and controls during resting-state and/or under task conditions. Results: We reviewed 15 studies involving 846 participants (424 aADHD and 422 controls), including 4 studies on sympathetic tone at rest, 13 studies on sympathetic modulation during tasks, 3 studies on resting state parasympathetic modulation and 3 papers on task-related parasympathetic modulation. Studies comprised measurements of electrodermal activity, heart rate variability, blood pressure variability, blood volume pulse, pre-ejection period, and baroreflex sensitivity. 2 studies reported reduced sympathetic tone in aADHD; 7 papers described lower sympathetic reactivity to task demands in this cohort. One study linked aADHD to impaired vagal tone, while no indications of altered tasks-related parasympathetic reactivity in aADHD patients were reported. Conclusion: The reviewed data revealed impaired cardiovascular autonomic modulation in aADHD patients, predominantly in sympathetic modulation and during stress exposure.

Improving our understanding of open access: how it relates to funding, internationality of research and scientific leadership

As open publication has become a goal in scholarly communication, interest in how it relates to other features of the research process has grown. This paper focuses on the relationship between funding and open access (OA) in the Spanish National Research Council’s Web of Science publications in three scientific fields with different research practices, namely, Biology & Biomedicine (BIOL), Humanities & Social Sciences (HSS) and Materials Science (MATE). Firstly, the three fields are characterised in relation to OA practices (OA status and OA routes) and acknowledged funding (funding status and funding origin). Secondly, the relationship between OA and funding is explored, and the role of additional influential factors, such as the internationality of research and national/foreign leadership of papers, is unravelled through logistic regression. BIOL shows a higher OA share (66%) than do the other two fields (around 33%). Funded research shows higher OA rates than unfunded research in the experimental fields, but not in HSS, where it is related to a shift towards more publications with article-processing charges. The internationality of research, measured through international collaboration or foreign funding, increases OA, albeit with differences across fields. Foreign-funded papers are more likely to be led by foreign researchers in all three fields, but a foreign first author increases the chances of OA publication in HSS only, perhaps because Spanish leaders in this field have not internalised the importance of OA. The research’s policy implications are reviewed.

Trends in Knowledge Management within Open Government

In realizing the aspirations as a democratic nation, the provision of high-quality information transparency by the government is essential, especially for the legislative body as the people's representation. To transform information into a fundamental consideration for public policies, effective knowledge management is needed from the community, who act as active users of this information transparency. This study aims to analyze the trends in research concerning knowledge management and open government. Data sources were obtained through the Web of Science for publications from 2019 to 2023, focusing on the fields of political science, management, and social reform. The applied method utilized bibliometric analysis with tools such as VOSviewer and Biblioshiny. The study's results identified a total of 2251 keywords, which were then refined to 259 keywords through data selection. From the VOSviewer analysis, the study yielded 1144 links and 4 clusters, indicating the interconnectedness among keywords. This interconnectedness was further illustrated through Network Visualization, Overlay Visualization, and Density Visualization. Meanwhile, the Biblioshiny analysis, conducted using the R Application, involved visualizations like WordCloud, TreeMap, and Trend Topics related to the keywords.

P-714 Clinical utility of FMR1 screening: risk factor or monogenic cause for POI

Abstract Study question Is there a risk factor association or a monogenic relationship between FMR1 premutation and developing Fragile X-associated primary ovarian insufficiency (FXPOI)? Summary answer There is an association between FMR1 premutation and FXPOI rather than a monogenic relationship, which is highly dependent on ethnicity. What is known already Among the 40 genes involved in primary ovarian insufficiency (POI), identified in our recent systematic review (Van Der Kelen et al., 2022), the FMR1 premutation is considered as the most common cause of POI. A premutation in the FMR1 gene is defined as a CGG trinucleotide repeat length between 55 and 200 in the 5′ untranslated region. The term FXPOI is used for women with premutation in FMR1 who have a loss of normal function of the ovaries before the age of 40. There is conflicting evidence about the relationship between POI and length of premutation FMR1 alleles. Study design, size, duration Curated publications identified in PubMed and Web of Science on genetics of human female infertility and sex development by using the MESH terms, key words and inclusion/exclusion criteria described in our comprehensive systematic review were subjected to screening for “FMR1 gene.” The articles included cover a period from 1988 to the 1st of November 2021. Participants/materials, setting, methods A total of 161 publications in PubMed and 61 unique publications in Web of Science were identified, and subsequently screened for triplet expansion, primary ovarian insufficiency, and/or early menopause. Of these, 56 papers were selected, excluding publications exclusively on males as well as studies on non-human species, pediatric cases, reviews, and expression studies. The study and control groups repeat numbers, ethnicity, and conclusions in the article are listed. Main results and the role of chance Expansion in CGG trinucleotide repeat length happens at female meiosis and the risk for expansion increases with an increasing number of CGG repeats. There is an intermediate zone between 45 and 55 CGG repeats when the allele may be stable or unstable. Among 56 publications, 54 describing FMR1 triplet repeat size in women with POI, 34 were studying only the women with POI (observational) while 20 were including also control group (comparative). 2 publications were meta-analyses in which 13 and 11 case control studies were included respectively, 5 studies being in common. POI-associated premutations showed a wide range of repeat sizes. Women carrying midsize range repeats (>70-<100) potentially have a higher risk for POI compared to the general population. In recent decades, population-based screenings have indicated that FMR1 premutations are not as prevalent in women with ovarian insufficiency as previous estimates have suggested, but they still represent a substantial cause of POI. When present, the number of AGG interruptions and the size of uninterrupted CGG repeats are directly correlated with the ovarian reserve. No increased risk of POI associated with a premutation was reported among populations of non-European descent, such as the Han Chinese, Indian, and Jordan populations. Limitations, reasons for caution Available reports are difficult to compare because the ethnicity and number of patients analyzed, availability of clinical data and the quality of results are different in each study. Additionally, an effect of X-inactivation in POI women with premutation was not studied. Wider implications of the findings Owing to the low penetrance and a molecular mechanism that has not yet been fully elucidated, the clinical utility of FMR1 screening in women with reduced ovarian reserve needs further investigation before clinical implication. Trial registration number N/A

Characterization of global research trends and prospects on platinum-resistant ovarian cancer: a bibliometric analysis.

In the last decades, growing attention has been focused on identifying effective therapeutic strategies in the orphan clinical setting of women with platinum-resistant ovarian cancer (PROC), generating thousands of original articles. However, the literature involving bibliometric analysis of PROC has not been published yet. This study hopes to gain a better understanding of the hot spots and trends in PROC by conducting a bibliometric analysis, as well as identify potential new research directions. We searched the Web of Science Core Collection (WOSCC) for PROC-related articles published between 1990 and 2022. CiteSpace 6.1.R2 and VOS viewer 1.6.18.0 were primarily utilized to evaluate the contribution and co-occurrence relationships of various countries and regions, institutes, and journals and to identify research hotspots and promising future trends in this research field. A total of 3,462 Web of Science publications were retrieved that were published in 671 academic journals by 1135 authors from 844 organizations in 75 countries and regions. The United States was the leading contributor in this field, and the University of Texas MD Anderson Cancer Center was the most productive institution. Gynecologic Oncology was the most productive journal, while the Journal of Clinical Oncology was the most cited and influential. Co-citation cluster labels revealed the characteristics of seven major clusters, including synthetic lethality, salvage treatment, human ovarian-carcinoma cell line, PARP inhibitor resistance, antitumor complexes, folate receptor, and targeting platinum-resistant disease. Keywords and references burst detection indicated that biomarkers, genetic and phenotypic changes, immunotherapy, and targeted therapy were the most recent and most significant aspects of PROC research. This study conducted a comprehensive review of PROC research using bibliometric and visual techniques. Understanding the immunological landscape of PROC and identifying the population that can benefit from immunotherapy, especially in combination with other therapeutic options (such as chemotherapy and targeted therapy), will continue to be the focal point of research.

Striving for High-Quality Publications: Motivational Profiles of Management Within a Bulgarian University Cluster

This article outlines the motivational profiles of two types of management stakeholders in a Bulgarian university cluster striving for more Scopus and Web of Science publications. This article draws on stakeholder and self-determination theories. It uses tools of online survey (among 99 managers at 5 state Bulgarian universities), Kendall’s rank correlation coefficient, expert evaluations, induction/deduction and comparison. Three typical motivational profiles are obtained in this study: 1 for the department head stakeholder, titled “department-dedicated manager profile”, and 2 for the top management stakeholder, titled “job-satisfaction seeking manager profile” and “university-dedicated manager profile”.

Comparative Analysis of Research Output of Tamil Nadu Agricultural University as Reflected in Scopus and Web of Science

The study presented in the paper has analyzed the research productivity of faculty members of Tamil Nadu Agricultural University for the period of 2001-2020. Total of 4372 publications in Scopus and 1980 publications in web of Science database were retrieved and compared the performance of the faculty members. This study analyzed the scientific parameters such as year-wise distribution of research productivity, most prolific authors, funding sponsors, Collaborating Institutions, Collaborating Countries and top-ranked sources preferred by the agricultural faculty members for publishing their research output. Tamil Nadu Agricultural University faculty members published more publications in Scopus 4372 compared to Web of Science 1980. Articles are the predominant publications by the faculty members of Tamil Nadu Agricultural University, Coimbatore 3928 in Scopus and 1822 in Web of Science Prof. Samiyappan R is the predominant and most impactful author of Tamil Nadu Agricultural University.USA is the most predominant country collaborated with Tamil Nadu Agricultural University publications about 187 in Scopus and 137 in Web of Science Legume Research is the most predominant journal with 69 publications in Web of Science and Electronic Journal of Plant Breeding 448 publications in Scopus. Agricultural College and Research Institute, Madurai is the most collaborating institution with 538 publications in Scopus and Kansas State University in Web of Science database.Plant Sciences (499), Agronomy (490), Biotechnology Applied Microbiology (190), Horticulture (159) and Environmental Science (129) are the predominant subject areas focused by the faculty members of Tamil Nadu Agricultural University in Web of Science and Agricultural and Biological Sciences subject category in Scopus 3317 publications. Indian Council of Agricultural Research is the predominant sponsor and supported for 104 research publications followed by Department of Biotechnology, Ministry of Science and Technology, India.

Land–Sea Interactions and Ecosystem Services: Research Gaps and Future Challenges

The land–sea interface is essential for understanding the interconnectedness of terrestrial and marine ecosystems and provides ecosystem services to people. Although research has been conducted on both ecosystems, knowledge about their interactions remains limited. While there has been growing research interest on land–sea interactions over the last decade, other types of knowledge system such as local or indigenous knowledge have not yet been included. The goal of this study is to review the literature related to land–sea interactions using an ecosystem services framework to help classify existing research. A systematic review of the literature was employed by searching peer-reviewed publications in Web of Science using land–sea interaction keywords. The synthesis identified 166 publications. The findings indicate that the primary disciplines that have investigated land–sea interactions were biogeochemistry and ecology, with a focus on nutrients and interactions. In terms of ecosystem services, supporting and regulating services were the most researched, with urbanization and agricultural and forestry effluents as main studied drivers. Results reveal a need for a more comprehensive view of land–sea interactions that recognizes the critical role that social factors play in shaping the sustainability of these systems. Therefore, a future challenge involves using a more holistic approach to the study and management of land–sea interactions.

Bibliometric Review of Electrification of Enterprise and Last-Mile Delivery Fleet

The impact of transport on carbon emissions accounts for 16.2 % of total global emissions, of which road transport accounts for 11.9 %. Road freight accounts for 40 % of road transport emissions and 4.76 % of global CO2 emissions. This study analyses the existing scientific literature in the field of transport electrification for transport companies in general and for ‘last mile delivery’ logistics companies specializing in urban delivery within parcel collection networks. The purpose of this study is to determine the state of the art for electric vehicles in fleets and how this topic can be assessed for sustainability. Bibliographic validation is primarily quantitative and is the most efficient method for dealing with the large volumes of information from the Web of Science (WoS) and Scopus databases. VOSviewer software was used to map the relationships between the most frequently used keywords in academic articles. The results show a small number of research papers addressing the electrification of fleet transportation. Only 1 of 523 WoS publications and 1 of 656 fleet transport publications in Scopus covered last-mile delivery for the selected period (1985–2022). It should also be noted that only 39 publications in 1987 in WoS database and 29 papers in 1891 in Scopus on transport electrification have sustainability rating links. The study reveals a lack of research in the subfield of transport electrification. The authors conclude that more research on sustainability criteria for fleet electrification is needed to support a smooth transition to EVs within this specific subfield of transport and to contribute to emission decrease in transport sector.

Curriculum in natural sciences in Latin America: analysis of research production

This article presents the results of a research project aimed at analyzing the academic discourses on curriculum in Latin American publications in Web of Science. For this purpose, the methodological route is based on bibliometrics and content analysis from the search, systematization, and analysis of the articles gathered in the documentary corpus. The consolidation of research networks between Latin American and foreign authors is evidenced. However, national work teams prevail, which show the low discussion of perspectives. On the other hand, thematic niches are found in which the research projects are grouped. These niches are: (1) conceptions of science, (2) didactics and teaching, (3) teacher training, (4) interculturality, and (5) scientific research. It is concluded that research in curriculum in natural sciences is a diverse field that unites not only different perspectives of science but also different perspectives of curriculum, since it is associated both to a practical space in the teaching of science and to a theoretical space that involves epistemological perspectives of science and structure of contents.

Clinical Characteristics of Human Mpox (Monkeypox) in 2022: A Systematic Review and Meta-Analysis.

Since May 2022, large numbers of human mpox (previously known as monkeypox) cases have been reported in non-endemic regions. We conducted a systematic review and meta-analysis to elucidate clinical characteristics of the current mpox outbreak. Our systematic review and meta-analysis were undertaken according to PRISMA and MOOSE guidelines. We searched PubMed, EMBASE, and Web of Science for publications between 1 January and 11 November 2022. Random-effects models were used to pool results. Heterogeneity was assessed using I2. This study is registered with PROSPERO, CRD42022355590. Skin lesions (95.2%, 95% CI [93.3-96.9%]), fever (58.4%, [54.9-61.8%]) and lymphadenopathy (53.0%, [48.7-57.3%]) were the most common symptoms. The most common dermatological manifestations were anogenital lesions (65.7%, [57.8-73.0%]), and the most common lymphadenopathy was inguinal (46.8%, [40.6-53.0%]). There were no differences in symptoms including malaise, fever, headache, and genital, anal, and oropharyngeal lesions according to HIV infection status. Median age of patients varied from 15 to 57.5 years (median, 35 years). The median proportion of men who had sex with men (MSM) was 100.0% (20.6-100.0%). The median proportion of patients who reported recent sexual exposure was 99.2% (14.3-100.0%). The median proportion of PLHIV was 42.2% (0.0-100.0%). Skin lesions, fever, inguinal lymphadenopathy, and anogenital lesions were the most common symptoms of mpox reported in the current outbreak. Existing guidelines should be updated to reflect these clinical manifestations and groups at highest risk of infection, MSM in particular.

Russian Publications in Web of Science: A bibliometric study

This article presents a bibliometric study of 1.38 million Russian publications indexed in Web of Science as of May 2022 without any restrictions as to document types, time periods, scientific disciplines, etc. From this perspective, the present analysis reflects Russian research’s true presence and visibility in the most prestigious scientific literature database. The main results obtained are: a) There was a rapid increase in research production in the 2010s, but the share of the Russian output in the global research production is still below 3%. b) International collaborative publications account for about 30% of Russian papers but around 70% of Russian citations. c) Physics, chemistry, and engineering are the most productive Russian research areas, but their citation impact is below the world average in those respective fields. d) The most frequently collaborating countries are the United States, Germany, and France, but Canada and Switzerland consistently contribute to the greatest relative citation impact of collaborative papers in the top ten research areas.

Estimation of liver fibrosis using elastography in cholestatic diseases: systematic review and meta-analysis.

staging fibrosis extent in liver disease is highly relevant for appropriate management. Liver biopsy remains the reference standard for assessment, but noninvasive methods such as elastography are becoming increasingly accurate and relevant. However, evidence regarding elastography in cholestatic diseases is lower than in other etiologies. we searched MEDLINE, EMBASE and Web of Science for publications on the diagnostic accuracy of transient elastography and sonoelastography in cholestatic diseases (PBC and PSC) using biopsy as the reference standard. A systematic review and meta-analysis of the results was then carried out. a total of 13 studies were included. Using transient elastography in PBC sensitivity and specificity were estimated to be 0.76 and 0.93; 0.88 and 0.9; and 0.91 and 0.95 for ≥ F2, ≥ F3 and = F4, respectively. For sonoelastography in PBC sensitivity and specificity estimates were 0.79 and 0.82; 0.95 and 0.86; and 0.94 and 0.85 for ≥ F2, ≥ F3 y = F4, respectively. In PSC, transient elastography had a sensivity and specificity of 0.76 and 0.88; 0.91 and 0.86; and 0.71 and 0.93 for ≥ F2, ≥ F3 and = F4, respectively. elastography has adequate diagnostic accuracy in the assessment of fibrosis stages in cholestatic liver diseases.