Psychophysical Interaction Research Articles

Embodied learning with metaphors and Rich Picture-like diagrams in actor training: an articulated, playful approach to teaching and practice-led research

Metaphors and diagrams are underutilised in actor training, both for teaching and practice-led research, creating a gap in the literature. Combining practice-led research and phenomenology as a methodology, this paper examines the author’s metaphor exercise “INTERACTION IS PLAYING TABLE TENNIS” and four Rich Picture-like diagrams, all constructed through a personal philosophy lens as an acting teacher/coach in the process of redefining Stanislavski’s term “communication” as “psychophysical interaction” and inventing the corresponding technique named “Transitive Psychophysical Interaction Score (TPI Score)”. This examination draws on an interdisciplinary perspective, incorporating Johan Huizinga’s cultural theory of “play” metaphor, George Lakoff and Mark Johnson’s, and Zoltán Kövecses’s theories of “conceptual metaphor”, along with Simon Bell, Tessa Berg, and Stephen Morse’s “Rich Pictures” concept, to reveal how metaphorical and visual elements rooted in physical experiences such as “games/sports”, “colour”, “icons”, and their inherent quality of “playfulness’ reshape actors” embodied understanding of the concept of “interaction” and fostering trainer-trainee dynamics. This inquiry also critically reflects on ineffective instructions commonly used by trainers, arguing that the combination of metaphor exercises and visual metaphors can bridge tacit and explicit knowledge in a structured, engaging way, thereby improving practitioners’ and researchers’ ability to articulate complex knowledge and reveal deep insights in teaching and academic writing, and fostering a more effective and relaxed communication. This creative approach to teaching and practice-led research can be used by a broader community of actor trainers and researchers in the future.

The Psychophysical Interaction: from Jonas’ intuitive model to the systematic model of SSP

The Psychophysical Interaction: from Jonas’ intuitive model to the systematic model of SSP

Mind–Body Interaction and Modern Physics

The idea that mind and body are distinct entities that interact is often claimed to be incompatible with physics. The aim of this paper is to disprove this claim. To this end, we construct a broad mathematical framework that describes theories with mind–body interaction (MBI) as an extension of current physical theories. We employ histories theory, i.e., a formulation of physical theories in which a physical system is described in terms of (i) a set of propositions about possible evolutions of the system and (ii) a probability assignment to such propositions. The notion of dynamics is incorporated into the probability rule. As this formulation emphasises logical and probabilistic concepts, it is ontologically neutral. It can be used to describe mental ‘degrees of freedom’ in addition to physical ones. This results into a mathematical framework for psycho-physical interaction (\(\Psi \Phi\)I formalism). Interestingly, a class of \(\Psi \Phi\)I theories turns out to be compatible with energy conservation.

The emotional face of anorexia nervosa: The neural correlates of emotional processing.

Social–emotional processing difficulties have been reported in Anorexia Nervosa (AN), yet the neural correlates remain unclear. Previous neuroimaging work is sparse and has not used functional connectivity paradigms to more fully explore the neural correlates of emotional difficulties. Fifty‐seven acutely unwell AN (AAN) women, 60 weight‐recovered AN (WR) women and 69 healthy control (HC) women categorised the gender of a series of emotional faces while undergoing Functional Magnetic Resonance Imaging. The mean age of the AAN group was 19.40 (2.83), WR 18.37 (3.59) and HC 19.37 (3.36). A whole brain and psychophysical interaction connectivity approach was used. Parameter estimates from significant clusters were extracted and correlated with clinical symptoms. Whilst no group level differences in whole brain activation were demonstrated, significant group level functional connectivity differences emerged. WR participants showed increased connectivity between the bilateral occipital face area and the cingulate, precentral gyri, superior, middle, medial and inferior frontal gyri compared to AAN and HC when viewing happy valenced faces. Eating disorder symptoms and parameter estimates were positively correlated. Our findings characterise the neural basis of social–emotional processing in a large sample of individuals with AN.

The processing of angry faces in schizophrenia patients with a history of suicide: An fMRI study examining brain activity and connectivity

BackgroundThe high rate of suicidal behaviours (SBs) in psychiatric populations remain an important preoccupation to address. The literature reveals emotional instability as an important risk factor for SBs. However, the neural mechanisms underpinning this risk factor have never been investigated in schizophrenia patients with SBs. The following study implemented a task-based emotional processing functional magnetic resonance imaging (fMRI) paradigm to evaluate the activation and connectivity differences exhibited by schizophrenia patients with a history of suicide attempt (SA). MethodA sample of 62 schizophrenia patients with and without SA and 22 controls completed an fMRI emotional processing task, which included the visualization of dynamic angry facial expressions. Task-based connectivity was assessed using generalized psychophysical interaction analyses. ResultsDuring the processing of angry faces, suicidal schizophrenia patients displayed increased activation of the left median cingulate gyrus, left middle frontal gyrus, and left precuneus when compared to nonsuicidal schizophrenia patients and healthy controls. Whole-brain connectivity analyses yielded an increased coupling of the right amygdala and right superior frontal gyrus, as well as between the left precuneus and median cingulate gyrus, in suicidal schizophrenia patients. Schizophrenia patients' hostility scores on the Positive and Negative Symptom Scale (PANSS) were significantly and positively correlated with the activity of the left median cingulate gyrus. ConclusionWhen exposed to angry faces, suicidal schizophrenia patients demonstrate elevated activation of brain regions associated to executive functioning and self-processing, as well as aberrant fronto-limbic connectivity involved in emotion regulation. Our results highlight the neglected role of anger when investigating the neural alterations underpinning SBs in schizophrenia.

A Sensorimotor Numerosity System.

Incoming sensory input provides information for the planning and execution of actions, which yield motor outcomes that are themselves sensory inputs. One dimension where action and perception strongly interact is numerosity perception. Many non-human animals can estimate approximately the number of external elements as well as their own actions, and neurons have been identified that respond to both. Recent psychophysical adaptation studies on humans also provide evidence for neural mechanisms responding to both the number of externally generated events and self-produced actions. Here we advance the idea that these strong connections may arise from dedicated sensorimotor mechanisms in the brain, part of a more generalized system interfacing action with the processing of other quantitative magnitudes such as space and time.

Fronto-parietal engagement in response inhibition is inversely scaled with attention-deficit/hyperactivity disorder symptom severity.

Impaired response inhibition is one of the most consistent findings in attention deficit hyperactivity disorder (ADHD). However, the underlying brain mechanisms are not clear. This study aimed to underpin atypical inhibition-related brain activation and connectivity patterns in ADHD using a novel Go/No-go task design, and to determine its association with clinical symptoms of the disorder. Forty-eight adults with ADHD performed a Go/No-go task in which target frequency was manipulated during functional MRI. Specific inhibition-related brain activation was correlated with ADHD symptom severity, to assess the relationship of individual differences in engagement of inhibition-related brain circuits with the magnitude of every-day functioning impairments. Finally, generalized psychophysical interaction analyses were carried out to examine whether not only engagement but also functional connectivity between regions implicated in response inhibition is related to symptom severity. We found no evidence for the expected parietal modulation by increased demand for inhibition at the group-level results. However, this lack of modulation was mediated by individual differences in ADHD symptom severity - increased engagement of the intraparietal sulcus (IPS) in inhibition-demanding events was evident in individuals with less severe symptoms but dissipated with increase in symptomatology. Similarly, functional connectivity between the IPS and the right inferior frontal gyrus (rIFG) was elevated under high inhibitory demand conditions, but this effect diminished with increased symptom severity. The results highlight the importance of IPS engagement in response inhibition and suggest that IPS modulation may be driven by top-down control from the IFG. Moreover, the current findings force the point of treating ADHD as a continuum whereby brain correlates are scaled with severity of the disorder, and point to the potential use of individual differences in the modulation of IPS activation and connectivity as a neuromarker of ADHD.

Amygdala-prefrontal cortex connectivity increased during face discrimination but not time perception.

Time sensitivity is affected by emotional stimuli such as fearful faces. The effect of threatening stimuli on time perception depends on numerous factors, including task type and duration range. We applied a two-interval forced-choice task using face stimuli to healthy volunteers to evaluate time perception and emotion interaction using functional magnetic resonance imaging. We conducted finite impulse response analysis to examine time series for the significantly activated brain areas and psycho-physical interaction to investigate the connectivity between selected regions. Time perception engaged a right-lateralised frontoparietal network, while a face discrimination task activated the amygdala and fusiform face area (FFA). No voxels were active with regard to the effect of expression (fearful versus neutral). In parallel with this, our behavioural results showed that attending to the fearful facesdid not cause duration overestimation. Finally, connectivity of the amygdala and FFA to the middle frontal gyrus increased during the face processing condition compared to the timing task.Overall, our results suggest that the prefrontal-amygdala connectivity might be required for the emotional processing of facial stimuli. On the other hand, attentional load, task type and task difficultyare discussed as possible factors that influence the effects of emotion on time perception.

Association Between Duration of Untreated Psychosis and Frontostriatal Connectivity During Maintenance of Visuospatial Working Memory

BackgroundA longer duration of untreated psychosis (DUP) has been linked with poor clinical outcomes and variation in resting-state striatal connectivity with central executive regions. However, the link between DUP and task-based activation of executive neurocognition has not previously been examined. This functional magnetic resonance imaging study examined the association between DUP and both activation and frontostriatal functional connectivity during a visual working memory (WM) paradigm in patients with first-episode psychosis. MethodsPatients with first-episode psychosis (n = 37) underwent functional magnetic resonance imaging scanning while performing a visual WM task. At the single-subject level, task conditions were modeled; at the group level, each condition was examined along with DUP. Activation was examined within the dorsolateral prefrontal cortex, a primary region supporting visual WM activation. Frontostriatal functional connectivity during the WM was examined via psychophysical interaction between the dorsal caudate and the dorsolateral prefrontal cortex. Results were compared with a reference range of connectivity values in a matched group of healthy volunteers (n = 25). Task performance was also examined in relation to neuroimaging findings. ResultsNo significant association was observed between DUP and WM activation. Longer DUP showed less functional frontostriatal connectivity with the maintenance of increasing WM load. Results were not related to task performance measures, consistent with previous work. ConclusionsOur data suggest that DUP may affect frontostriatal circuitry that supports executive functioning. Future work is necessary to examine if these findings contribute to the mechanism underlying the relationship between DUP and worsened clinical outcomes.

Интегративный подход как психологическое основание исследования социоприродного взаимодействия

The paper discusses the application of the integrative approach in the study of the psychological mechanisms of social-ecological interaction. We suggest that defining the principle of interaction between man and nature is important, as this provides the opportunity for scientific substantiation for the processes of subjectifying natural objects. The result of the process is the invocation of more subtle mechanisms of perception revealing the response of the natural world that was poorly accentuated at the time of interaction or unrecognised due to the unpreparedness of the subject of perception. The integrative approach is considered as a concept that includes both intrapsychic integration, which involves a deep connection of mental functions and formations, and interpsychic integration, which allows us to reveal the relationship between man and the living environment, including its natural component. We assume that in order to discover himself as a natural being, an individual has to assess and correctly identify the boundaries of interaction between the individual and the natural being. In this process, the role of using nature as a tool for reflection on various characteristics of the subject’s activity and for building intrapsychic and interpsychic connections and relationships is emphasized. The natural environment in the representation of man is a set of different natural objects and their connections and relationships that have developed as a result of long-term evolution. The uncertainty, complexity, diversity and dynamics of these relationships are the obstacles in the way of building a systematic representation of the world. Thus an individual needs to create specific tools to facilitate psychophysical interaction with nature, in which every step forward, carried out with the help of engineering devices, requires a deep understanding of the consequences both for the individual, and the surrounding natural objects. Objectification of the environment and selection of useful properties of natural objects in the process of learning are generally limited by the accompanying adverse effects, and therefore may be accompanied by moral prohibitions. In this aspect, the integrative approach can be effective for the analysis of approaches to the unification of the natural sphere, the psychosphere and the technosphere. The paper attempts to demonstrate the productivity of the functional analysis of the interaction process between man and nature on the grounds of implicitness (the focus on intrapsychic education) and explicitness (the focus on the identification of mental properties of an individual and the creative transformation of the living environment), revealing psychological mechanisms linking and supporting the unity of man and nature.

Electrical stimulation reduces smokers' craving by modulating the coupling between dorsal lateral prefrontal cortex and parahippocampal gyrus.

Applying electrical stimulation over the prefrontal cortex can help nicotine dependents reduce cigarette craving. However, the underlying mechanism remains ambiguous. This study investigates this issue with functional magnetic resonance imaging. Thirty-two male chronic smokers received real and sham stimulation over dorsal lateral prefrontal cortex (DLPFC) separated by 1 week. The neuroimaging data of the resting state, the smoking cue-reactivity task and the emotion task after stimulation were collected. The craving across the cue-reactivity task was diminished during real stimulation as compared with sham stimulation. The whole-brain analysis on the cue-reactivity task revealed a significant interaction between the stimulation condition (real vs sham) and the cue type (smoking vs neutral) in the left superior frontal gyrus and the left middle frontal gyrus. The functional connectivity between the left DLPFC and the right parahippocampal gyrus, as revealed by both psychophysical interaction analysis and the resting state functional connectivity, is altered by electrical stimulation. Moreover, the craving change across the real and sham condition is predicted by alteration of functional connectivity revealed by psychophysical interaction analysis. The local and long-distance coupling, altered by the electrical stimulation, might be the underlying neural mechanism of craving regulation.

Altered praxis network underlying limb kinetic apraxia in Parkinson's disease - an fMRI study.

Parkinson's disease (PD) patients frequently suffer from dexterous deficits impeding activities of daily living. There is controversy whether impaired fine motor skill may stem from limb kinetic apraxia (LKA) rather than bradykinesia. Based on classical models of limb praxis LKA is thought to result when premotor transmission of time-space information of skilled movements to primary motor representations is interrupted. Therefore, using functional magnetic resonance imaging (fMRI) we tested the hypothesis that dexterous deficits in PD are associated with altered activity and connectivity in left parieto-premotor praxis network. Whole-brain analysis of fMRI activity during a task for LKA (coin rotation) showed increased activation of superior and inferior parietal lobule (SPL, IPL) and ventral premotor cortex (vPM) in PD patients compared to controls. For bradykinesia (assessed by finger tapping) a decreased fMRI activity could be detected in patients. Additionally, psychophysical interaction analysis showed increased functional connectivity between IPL and the posterior hippocampi in patients with PD. By contrast, functional connectivity to the right dorsolateral prefrontal cortex was decreased in patients with PD compared to controls.In conclusion, our data demonstrates that dexterous deficits in PD were associated with enhanced fMRI activation of the left praxis network upstream to primary motor areas, mirroring a neural correlate for the behavioral dissociation of LKA and bradykinesia. Furthermore, the findings suggest that patients recruit temporal areas of motor memory as an attempt to compensate for impaired motor skills. Finally, dysexecutive function may contribute to the deficit.

Abnormal effective fronto-limbic connectivity during emotion processing in schizophrenia

BackgroundSchizophrenia is associated with core emotional dysfunctions. At the neural level, functional neuro-imaging studies have highlighted fronto-limbic alterations during emotion processing in schizophrenia, as well as impaired connectivity between the amygdala and the prefrontal cortex. However, the direction of the impaired fronto-limbic connections remains largely unknown. To clarify this issue, we performed an effective connectivity study on emotion processing in schizophrenia. MethodsForty-one healthy individuals and 39 schizophrenia patients (DSM-IV criteria) viewed negative, positive and neutral images during an fMRI session. Effective connectivity between significantly activated regions was examined using Granger causality and psychophysical interaction analyses. ResultsSubjective ratings of emotionally neutral images were higher in schizophrenia patients than in controls. Across groups, significant activations were observed in the dorso-medial prefrontal cortex (dmPFC) and the bilateral amygdala. The Granger connectivity from the right amygdala to the dmPFC was significantly reduced in schizophrenia patients, relative to controls, during the negative and neutral conditions. The Granger connectivity from the left amygdala to the dmPFC was significantly reduced in schizophrenia patients, relative to controls, during the positive condition. DiscussionThe finding of a reduced lagged connectivity from the bilateral amygdala to the dmPFC in schizophrenia suggests that the bottom-up mechanisms involved in the processing of highly arousing emotional stimuli are impaired in this disorder. The finding of an impaired lagged connectivity from the right amygdala to the dmPFC during the processing of emotionally neutral stimuli in schizophrenia is novel and may explain why these patients tend to confer emotional significance to irrelevant stimuli.

Powers, Double Prevention and Mental Causation

Abstract S. C. Gibb holds that some mental events enable physical events to take place by acting as ‘double preventers’ which prevent other mental events from effecting change in the physical domain. She argues that this enables a dualist account of psychophysical interaction consistent with the causal relevance of mental events, their distinctness from physical events, the causal closure of the physical and the exclusion of systematic overdetermination. While accepting the causal powers metaphysic, this paper argues that: Closure is maintained only on the assumption of an implausible pre-ordained harmony between preventing and double-preventing mental events. Distinctness is preserved only at the cost of positing brute unexplained powers of mental and physical events to causally interact with each other. Exclusion is systematically violated in a substantial number of everyday cases. The case for Relevance made by the Double Prevention model is accordingly too weak to sustain a dualist approach to mental causation.

OUTLINES OF SYSTEMIC UNDERSTANDING OF PSYCHE

The methodological grounds of systemic approach to a psyche research are considered. Its major problems are grounded through the retrospective analysis of key systems paradigms from Aristotle to psychosynergy. We can single out among them the following: the allocation of the internal mental environment due to which the survival in the world is provided; justification of the principles of psychophysical interaction; understanding of the phenomena of a homeostasis, which provide dynamic stability of a mental system qualities; detection of regularities concerning the relations of the internal mental environment to non-systemic “challenges”. Prospects of psychosynergy methodology in the research of psyche as a complicated system of the open self-organizing psychomeasured environments are grounded.

Sex differences in effective fronto-limbic connectivity during negative emotion processing

In view of the greater prevalence of depression and anxiety disorders in women than in men, functional magnetic resonance imaging (fMRI) studies have examined sex-differences in brain activations during emotion processing. Comparatively, sex-differences in brain connectivity received little attention, despite evidence for important fronto-limbic connections during emotion processing across sexes. Here, we investigated sex-differences in fronto-limbic connectivity during negative emotion processing. Forty-six healthy individuals (25 women, 21 men) viewed negative, positive and neutral images during an fMRI session. Effective connectivity between significantly activated regions was examined using Granger causality and psychophysical interaction analyses. Sex steroid hormones and feminine-masculine traits were also measured. Subjective ratings of negative emotional images were higher in women than in men. Across sexes, significant activations were observed in the dorso-medial prefrontal cortex (dmPFC) and the right amygdala. Granger connectivity from right amygdala was significantly greater than that from dmPFC during the 'high negative' condition, an effect driven by men. Magnitude of this effect correlated negatively with highly negative image ratings and feminine traits and positively with testosterone levels. These results highlight critical sex differences in brain connectivity during negative emotion processing and point to the fact that both biological (sex steroid hormones) and psychosocial (gender role and identity) variables contribute to them. As the dmPFC is involved in social cognition and action planning, and the amygdala-in threat detection, the connectivity results suggest that compared to women, men have a more evaluative, rather than purely affective, brain response during negative emotion processing.

Disrupted functional connectivity in dorsal and ventral attention networks during attention orienting in autism spectrum disorders.

Attention orienting is a cognitive process that facilitates the movement of attention focus from one location to another: this may be impaired in autism spectrum disorder (ASD). Dorsal and ventral attention networks (DAN and VAN) sub-serve the process of attention orienting. This study investigated the functional connectivity of attention orienting in these networks in ASD using the Posner Cueing Task. Twenty-one adolescents with ASD and 21 age and IQ matched controls underwent functional magnetic resonance imaging. A psychophysical interaction (PPI) analysis was implemented to investigate task-dependent functional connectivity, measuring synchronicity of brain regions during the task. Regions of interest (ROI) were selected to explore functional connectivity in the DAN during cue-only conditions and in the VAN during invalid and valid trials. Behaviourally, the ASD and control groups performed the task in a similar manner. Functional MRI results indicated that the ASD and control groups activated similar brain regions. During invalid trials (VAN), the ASD group showed significant positive functional connectivity to multiple brain regions, whilst the control group demonstrated negative connectivity. During valid trials (VAN), the two groups also showed contrasting patterns of connectivity. In the cue-only conditions (DAN), the ASD group showed weaker functional connectivity. The DAN analysis suggests that the ASD group has weaker coherence between brain areas involved in goal-driven, endogenous attention control. The strong positive functional connectivity exhibited by the ASD group in the VAN during the invalid trials suggests that individuals with ASD may generate compensatory mechanisms to achieve neurotypical behaviour. These results support the theory of abnormal cortical connectivity in autism.

Motion defined surface segregation in human visual cortex

Event Abstract Back to Event Motion defined surface segregation in human visual cortex Gabriel J. Vigano1, 2*, Ryan T. Maloney1, 2 and Colin W. Clifford1, 2 1 University of Sydney, School of Psychology, Australia 2 Australian Research Council Centre of Excellence in Vision Science, Australia Background Surface segregation provides an efficient way to distinguish between objects in the world. It is a relatively fast process which can speed feature binding. For example, a stimulus alternating simultaneously between two visual features (eg. colour and motion) at a high frequency appears transparent due to surface segregation. Both sets of features persist simultaneously and the colour-motion pairing can be easily identified. However, at a lower alternation frequency, the representation of multiple surfaces breaks down making binding difficult. Here, we investigated motion defined surface transparency through a psychophysical task and fMRI. Methods Two oppositely rotating random dot kinematograms (RDKs) were displayed at several alternation frequencies, presented either sequentially or simultaneously. Sequential presentations displayed one RDK on screen at any time while the simultaneous display contained both RDKs in concentric, alternating strips. The psychophysical task contained coloured RDKs and was a presentation (sequential, simultaneous) by alternation frequency (1.67, 2.5, 3.33, 5, 7.5 and 15Hz) experiment. Participants reported the colour-motion pairing. The fMRI experiment had a presentation (sequential, simultaneous) by frequency (5, 15Hz) design using grey RDKs. Results A significant presentation × frequency interaction was apparent in the psychophysical results. At 15 Hz, sequential and simultaneous displays produced ceiling performance indicative of perceived transparency. However, transparency broke down in the sequential presentation at 5 Hz, generating chance performance, while simultaneous presentations continued to appear transparent independent of frequency. This was also reflected in univariate as well as multivariate analyses of the fMRI BOLD activity in V1, V2, V3, V3AB, hV4, and V5/MT+. We found significant presentation by frequency interaction effects in most areas, such that changes in BOLD signal between presentation types were significantly different only at 5Hz. Multivariate pattern classification confirmed this result, finding significantly higher than chance decoding between presentation types at 5, but not 15Hz. Discussion Perceptual transparency was found to be correlated with neural activity in early visual areas. fMRI data mirrored psychophysical interaction effects in qualitatively similar ways, suggesting surface representations may be associated with activity in early areas of the human visual cortex. Keywords: human fMRI, feature binding, surface perception, Psychophysics, temporal transparency Conference: ACNS-2013 Australasian Cognitive Neuroscience Society Conference, Clayton, Melbourne, Australia, 28 Nov - 1 Dec, 2013. Presentation Type: Poster Topic: Sensation and Perception Citation: Vigano GJ, Maloney RT and Clifford CW (2013). Motion defined surface segregation in human visual cortex. Conference Abstract: ACNS-2013 Australasian Cognitive Neuroscience Society Conference. doi: 10.3389/conf.fnhum.2013.212.00118 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 16 Sep 2013; Published Online: 25 Nov 2013. * Correspondence: Mr. Gabriel J Vigano, University of Sydney, School of Psychology, Sydney, Australia, gvig3764@uni.sydney.edu.au Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Gabriel J Vigano Ryan T Maloney Colin W Clifford Google Gabriel J Vigano Ryan T Maloney Colin W Clifford Google Scholar Gabriel J Vigano Ryan T Maloney Colin W Clifford PubMed Gabriel J Vigano Ryan T Maloney Colin W Clifford Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.

Imagined tool-use in near and far space modulates the extra-striate body area

Active tool-use can result in the incorporation of the tool into the body schema, e.g., the representation of the arm is enlarged according to tool length. This modification even influences the processing of space: using a long tool leads to a remapping of far space as near space. We here further investigate the interaction of the neural representations of the human body, tool use, and spatial domain.Functional magnetic resonance imaging (fMRI) was performed in twelve right-handed healthy individuals while they imagined moving a cylinder towards a target position in far or near space by mentally using either pliers or a joystick. The fMRI data revealed that already the imagined use of preferred tools in near and far space (i.e., pliers in far space, joystick in near space) modulated the neural activity in the extra-striate body area (EBA) located in the occipito-temporal cortex. Moreover, psycho-physical interaction analysis showed that during imagined tool-use the functional connectivity of left EBA to a network representing the near-personal space around the hand was strengthened. This increased functional connectivity is likely to reflect the neural processes underlying the incorporation of the tool into the body schema.Thus, the current data suggest that simulating tool-use modulates the representation of the human body in extra-striate cortex.

Fatores clínicos, funcionais e inflamatórios associados à fadiga muscular e à fadiga autopercebida em idosas da comunidade

Fatigue is a common and nonspecific symptom associated with chronic health problems in the elderly. The modifications and adaptations of the aging process associated with complex and multidimensional nature of fatigue favors the interaction of multiple factors in the genesis of this phenomenon. To investigate the association of clinical, functional and inflammatory factors with muscle fatigue and self perceived fatigue in elderly women. Participated in the study one hundred and thirty five community elderly women, all sedentary, with a mean age of 71.2±4.57. A structured questionnaire and functional testing were used to evaluate clinical and functional characteristics. Plasma concentrations of inflammatory mediators (IL-6 and sTNFR1) were measured by ELISA method. Muscle fatigue was measured by isokinetic dynamometer and self-perceived fatigue was measured by a visual analog scale. Statistical analysis was performed by multiple linear regression and Spearman correlation coefficient with statistical significance of 5%. The regression models showed that the variables age, body mass index, physical activity level, functional capacity and peak torque were associated with muscle fatigue (R²=0.216, p<0.01). Self-perceived fatigue was associated with number of comorbidities, depression, physical activity level, functional capacity, peak torque and perceived health (R²=0.227, p<0.01). This study showed a psychophysical interaction of the fatigue, by identifying the main factors associated with muscle fatigue and self-perceived fatigue in elderly women. These findings demonstrate the importance of evaluation and treatment of modifiable factors in both muscle fatigue and self-perceived fatigue, seeking a better physical and functional performance of elders.