Psychological Well-being Outcomes Research Articles

The Role of Maternal Psychological Well-Being as a Predictor of Children’s Internalizing Behaviors

Nowadays, mothers' psychological well-being and behavioral outcomes in children have become a major topic of interest globally in the social and clinical arena. Though fathers play an important role in parenting, mothers are the key persons responsible for caring for their children. Thus, the present study investigated the relationship between maternal psychological well-being and their children's internalizing behaviors. This study also aimed to build up some models related to predictor and outcome variables based on the current research findings. A cross-sectional survey research design was employed to conduct the study on 800 participants (400 children and 400 mothers). The children were selected from ten Bangla medium high schools in Dhaka, and the age ranges of the children ranged from 11 to 13 years. The schools and the children were selected following a multistage random sampling technique. The self-reported Bangla version of the Strengths and Difficulties Questionnaire (SDQ), the Bangla version of the General Health Questionnaire (GHQ-28), and a Personal Information Form (PIF) were administered to the participants to collect data. The correlation analysis showed a significant positive correlation between maternal psychological well-being and children's internalizing behavior. Results also revealed that somatic symptoms, anxiety and insomnia, social dysfunction, and severe depression in mothers were significantly correlated with the internalizing behavior of children. Findings from multiple regression analysis indicated that the most powerful predictor of internalizing behavior was mothers' anxiety and insomnia, which independently explained 35% of the variance. The other significant predictors were social dysfunction, severe depression, and somatic symptoms. All four predictors jointly explained 40.6% of the variance in children's internalizing behavior. The implications of the findings have been discussed in light of theory and research evidence from earlier research. Jagannath University Journal of Life and Earth Sciences, 9(1): 45–56, 2023 (June)

Developing the WE BEAT Well-Being Education Programme to foster resilience and build connection in paediatric heart disease.

The study of psychological well-being and related resilient outcomes is of increasing focus in cardiovascular research. Despite the critical importance of psychological well-being and related resilient outcomes in promoting optimal cardiac health, there have been very few psychological interventions directed towards children with heart disease. This paper describes the development and theoretical framework of the WE BEAT Wellbeing Education Program, a group-based psychoeducation and coping skills training intervention designed to improve psychological well-being and resilience in adolescents with paediatric heart disease. Program development was informed by patient and family needs and input gathered via large, international survey methods as well as qualitative investigation, a theoretical framework, and related resilience intervention research. An overview of the WE BEAT intervention components and structure of the programme is provided. The WE BEAT Wellbeing Education Program was developed as one of the first resiliency-focused interventions in paediatric heart disease with an overall objective to foster positive psychological well-being and resilient outcomes through a health promotion and prevention lens in an accessible format while providing access to safe, peer-to-peer community building. Feasibility pilot results are forthcoming. Future directions include mobile app-based delivery and larger-scale efficacy and implementation trials.

Association between nomophobia and learning performance among undergraduate students: the mediating role of depression and anxiety

BackgroundThere is a gap in the existing literature concerning the connection between nomophobia and diminished academic performance, potentially influenced by anxiety and depression. The present study aimed to examine the relationship between undergraduate students’ nomophobia and learning outcomes, and whether depression and/or anxiety mediate this potential link.MethodsA quantitative cross-sectional survey design was employed. Nomophobia, anxiety, and depression were measured in 307 undergraduate students using validated self-report questionnaires. Learning performance was assessed based on participants’ grade point averages. Correlation analysis and mediation analysis were conducted to test the hypotheses.ResultsThe Pearson correlation analysis and multiple parallel mediation modeling suggest that anxiety plays a significant role as a causal pathway through which nomophobic behavior leads to lower grades among university students compared to their less anxious peers. Depression had no significant mediation effect.ConclusionThe findings support the notion that nomophobia is linked to poor academic achievement. The detrimental impact of nomophobia on learning performance appears to be more closely tied to anxiety rather than depression. This research contributes to the understanding of the complex interplay between technology use, psychological well-being, and educational outcomes in the higher education context. The study’s implications include the validation of the measurement scales in a non-English population and the recognition of the influence of technology on mental health and academic outcomes.

Sociocultural predictors of immigrant adjustment and well-being.

Research shows that culture change may pose risks to immigrant wellbeing. Our study examined adult Georgians (N = 431) residing in Greece, Italy, and Germany, and explored associations between their demographic characteristics, sociocultural adjustment, and psychological well-being outcomes. Conducted via electronic self-report survey, the cross-sectional study measured participants' levels of sociocultural adjustment, psychological adjustment, and depression along with the willingness to interact with host nationals, perceived sense of discrimination, history of being undocumented, age and length of relocation, and fluency in host language. The study also examined differences in three subsamples from the standpoint of intercultural distance. Sociocultural Adjustment Scale, Brief Psychological Adaptation Scale, Center for Epidemiologic Studies Depression Scale and Host Interaction Scale were used to measure the corresponding variables. Perceived history of discrimination was measured by a Likert-scale question about discrimination in a host country. Intercultural distance was established by Hofstede cultural compass and was estimated to be the smallest with Greece and the largest with Germany. Depression was positively predicted by histories of discrimination and illegal immigration, host language fluency upon relocation, and was negatively predicted by sociocultural adjustment. Psychological adjustment was positively predicted by sociocultural adjustment, willingness to interact with host nationals, and ongoing language fluency, while perceived sense of discrimination, age, and poor financial state acted as negative predictors. Finally, sociocultural adjustment acted as the strongest determinant of wellbeing predicting both lower depression and higher psychological adjustment. Our findings suggested that adjustment in diverse sociocultural domains was the most critical for the immigrants' psychological well-being along with the lack of perceived discrimination. Additional factors associated with the better adaptation outcomes included younger age, willingness to interact with host nationals, language fluency, better financial standing and no history of being undocumented. The results also indicated that host language proficiency upon relocation may contribute to migrant susceptibility, whereas intercultural distance may be overshadowed in importance by acculturation conditions. The findings illustrate the complexity of migration and culture change and point to the superiority of wholistic policies and practices in promoting smooth transition of immigrant populations.

Exploring the Relationship between Psychoneuroimmunology and Oral Diseases: A Comprehensive Review and Analysis.

The relationship between psychoneuroimmunology (PNI) and oral health has recently garnered increasing attention due to the intricate interaction among psychological factors, the nervous system, immune responses, and oral diseases. This comprehensive review aims to elucidate the multifaceted connections between PNI and various oral conditions and conduct an in-depth analysis. Psychological factors, such as stress, anxiety, and depression, have been linked to oral microbiome alterations and immune function and the development and progression of oral diseases, such as periodontal disorders, oral ulcers, and temporomandibular disorders. Conversely, oral health conditions, particularly chronic periodontitis, have been associated with systemic inflammation, affecting mental health and overall well-being through neuroendocrine-immune pathways. Moreover, neural mechanisms, including the brain-gut axis and the autonomic nervous system, significantly influenced oral health through immune modulation and inflammatory responses. Understanding these complex interactions has implications for therapeutic interventions that target both psychological well-being and oral health outcomes. This review synthesizes current research findings from various disciplines, including immunology, neuroscience, dentistry, and psychology, to offer a comprehensive understanding of the bidirectional relationship between PNI and oral diseases. The implications of these interactions on treatment strategies, preventive measures, and interdisciplinary approaches underscore the need for integrated healthcare models that address psychological and oral health aspects to improve outcomes and quality of life in patients.

Gratitude, optimism, and satisfaction with life and patient-reported outcomes in patients undergoing hematopoietic stem cell transplantation.

Associations between positive psychological well-being (PPWB) and patient-reported outcomes (PROs, e.g., quality of life [QOL]) have yet to be studied extensively in patients with hematologic malignancies who are allogeneic hematopoietic stem cell transplant (HSCT) survivors, despite substantial evidence that PPWB impacts PROs of other medical populations. We conducted a secondary analysis of cross-sectional data examining the association of PPWB and PROs at day 100 post-transplant among 158 allogeneic HSCT recipients. Optimism, gratitude, life satisfaction, and PROs (i.e., QOL, anxiety, depression, and PTSD symptoms) were assessed using the Life Orientation Test-Revised, Gratitude Questionnaire, Satisfaction with Life Scale, Functional Assessment of Cancer Therapy-Bone Marrow Transplant, Hospital Anxiety and Depression Scale, and Post-Traumatic Stress Disorder (PTSD) Checklist-Civilian Version, respectively. We used linear and multivariate regressions for all analyses and controlled for patient factors. Optimism was associated with better QOL (β=1.46; p<0.001) and lower levels of anxiety (β=-0.28; p<0.001), depression (β=-0.31; p<0.001), and PTSD (β=-0.58; p<0.001). Gratitude was associated with better QOL (β=1.11; p<0.001) and lower levels of anxiety (β=-0.21; p=0.001), depression (β=-0.14; p=0.021), and PTSD (β=-0.32; p=0.032). Finally, satisfaction with life was associated with better QOL (β=1.26; p<0.001) and lower levels of anxiety (β=-0.18; p<0.001), depression (β=-0.21; p<0.001), and PTSD (β=-0.49; p<0.001). Optimism, gratitude, and satisfaction with life were all associated with better QOL and lower levels of psychological distress in allogeneic HSCT survivors. These data support studies to harness PPWB as a therapeutic intervention for this population throughout HSCT recovery.

Divine struggles and whole person functioning: a 9-year longitudinal study of middle-aged U.S. adults

Objective This longitudinal study examined the associations of divine struggles with 25 psychological distress, psychological well-being, social well-being, prosociality, physical health, and health behavior outcomes assessed approximately nine years later. Methods We used three waves of data from the National Survey of Midlife Development in the United States (N = 4041): M1 (1995–1996), M2 (2004–2006), and M3 (2013–2014). Following the analytic template for outcome-wide longitudinal designs, our primary analysis employed a series of regression models to estimate the associations between a continuous measure of divine struggles assessed at M2 with each outcome assessed at M3. All models adjusted for a rich set of covariates, including prior values of all outcomes. Results There was modest evidence suggesting that divine struggles were associated with worse subsequent functioning on one or more outcomes for each domain except health behaviors (effect sizes were generally very small). Conclusions Divine struggles have the potential to degrade long-term functioning across multiple domains of life. Practitioners should attend to and address divine struggles in their clinical work.

Community gardens and psychological well-being among older people in elderly housing with care services: The role of the social environment

With population aging, increasing numbers of elderly people in Japan are expected to enter aged care facilities (ACFs). Although research has shown that access to community gardens (CGs) is generally beneficial to older people's psychological well-being, the mechanisms by which the usage and quality of CGs influence the well-being of older adults in ACFs remain insufficiently studied. Therefore, this study aims to explore the associations between garden factors (i.e., garden visit frequency and perceived garden quality) and older adults' psychological well-being outcomes (i.e., positive well-being and self-rated health) and to investigate the mediating role of neighborhood social environment factors (i.e., outing frequency, social participation, perceived neighborhood social cohesion, and perceived neighborhood attachment) in these associations. We conducted a questionnaire survey with 322 older adults from twelve elderly housing with care services (EHCSs) in the Tokyo metropolitan area (TMA) of Japan. The multiple regression models showed that both garden factors were positively associated with positive well-being and self-rated health. The parallel mediation models showed that higher garden visit frequency and perceived garden quality were associated with higher outing frequency and perceived neighborhood social cohesion and, in turn, with higher positive well-being. Moreover, higher garden visit frequency and perceived garden quality were associated with greater social participation and thereby with better self-rated health; higher perceived garden quality was also associated with higher perceived neighborhood attachment and thus with better self-rated health. Our findings elucidate the potential mechanisms underlying the beneficial associations between CGs and the psychological well-being of older adults in ACFs, emphasizing the important role of cultivating friendly social environments in CGs in enhancing healthy aging.

Adaptability and Social Support: Examining Links with Engagement, Burnout, and Wellbeing among Expat Teachers

(1) Background: Expatriate (expat) teachers, i.e., those living and working outside of their own country, face several unique challenges. Without sufficient protective resources, these challenges threaten to negatively impact upon their workplace engagement and psychological wellbeing, and lead to burnout. In the present study, we utilise the ‘conservation of resources’ (COR) theory to examine the influence of expat teachers’ adaptability (a personal resource) and social support (a conditional/situational resource) on their workplace engagement, burnout, and psychological wellbeing. (2) Methods: A sample of expat teachers (N = 88), mostly working and residing in Middle Eastern countries, completed a series of validated self-report scales to measure each substantive construct. (3) Results: Results revealed that adaptability, but not social support, was a significant positive predictor of both work engagement and psychological wellbeing. There were no significant interaction effects observed. Moreover, neither adaptability nor social support were associated with burnout in this study. Personal resources, such as adaptability, may be more significant determinants of workplace engagement and psychological wellbeing among expat teachers relative to conditional/situational resources, such as social support, according to this research. (4) Conclusions: These findings have important implications for researchers, practitioners, and businesses/organisations, underlining the need to concentrate on strengthening personal resources such as adaptability to improve workplace engagement and psychological wellbeing outcomes among expat teachers.

Household debt and children’s psychological well-being in China: The mediating role of parent–child relations

BackgroundHousehold debt is a psychological stressor for those who take the debt on, but it remains unclear whether and how this money-related stressor influences children’s psychological well-being. AimsThe study investigated the association of household debt with children’s psychological well-being and further explored the mediating role of parent–child relations. MethodsData were obtained from two waves (2016 and 2018) of the China Family Panel Studies, with a sample of 1,828 children included. The Center for Epidemiological Studies of Depression Scale was applied to measure psychological well-being. Household debt was assessed by absolute and relative amounts of total debt, mortgage debt, and non-mortgage debt. We used positive and negative parent–child interaction to measure parent–child relations. The characteristics of children, parents, and households were included as covariates. ResultsHousehold debt, especially mortgage debt, was positively associated with psychological illnesses among children, and the link was substantially explained by parent–child relations. ConclusionHousehold debt exerted detrimental effects on children’s psychological well-being by jeopardizing parent–child relations in China. Strategies that address the need of vulnerable children are required to reduce the potentially negative psychological well-being outcomes of household debt.

DISSECTING RACIAL DIFFERENCES IN THE PERCEPTION OF DOMAIN-SPECIFIC LIFE SATISFACTION

Abstract This study examines factors contributing to racial differences in domain-specific life satisfaction. Our study offers a major contribution to prior research that has tended to pay greater attention to psychological well-being outcomes such as life satisfaction which do not directly pertain to material circumstances of older adults. Those studies generally report better life satisfaction and fewer depressive symptoms among Black older adults than their White counterparts. Our study is based on 409 randomly selected older adults from Cleveland (mean age 79 and 25% African American). We considered socioeconomic status, stressors such as recent negative life events and coping resources such as religiosity to understand their impact on domain specific life- satisfaction (e.g., satisfaction with neighborhood, housing, and standard of living). Our ordinary least squares regression estimates suggest that, on average, Black older adults reported lower levels of domain-specific life satisfaction (b=-0.81, p&amp;lt; 0.01) compared to their White counterparts, despite having stronger social support and being more religious. Even though social support and religiosity did not contribute to racial differences in domain specific life satisfaction, the inclusion of education, income, and recent negative life events fully explain such differences. Findings indicate that interrelated factors such as socioeconomic disadvantage and greater life adversities such as negative life events contribute to lower domain life satisfaction among Black older adults. This finding highlights the need for further exploration of factors shaping material-related well-being outcomes for Black older adults. Our study informs future policies addressing racial well-being inequities.

An examination of the unique contributions of body image and internalized weight bias to psychological well-being outcomes

High correlations between measures of internalized weight bias (IWB) and body image (BI) have resulted in concerns that IWB is conceptually redundant with BI. This investigation examined the contribution of the unique variance of BI and IWB on three important, weight-related factors: self-esteem, depressive symptoms, and body shame. The study included 403 participants recruited through a Qualtrics research panel. Participants were required to be aged 18 + and have a BMI > 25. The sample contained three equally represented, self-identified racial/ethnic groups: Black non-Hispanic (N = 140), Hispanic (N = 133), and White non-Hispanic (N = 130). When BI was entered in the first step of the regression model, it accounted for 14–40% of the variance in various models; the addition of IWB in step two contributed 11–18% of unique variance. By contrast, when IWB was entered in the first step, it accounted for 25–56% of the variance in various models, with the addition of BI contributing between 0% and 2% unique variance. Therefore, even with a high correlation among the constructs of IWB and BI, IWB was able to contribute unique variance in predicting depressive symptoms, self-esteem, and body shame, and is not redundant with the construct of BI.

Patient-reported oral function and psychological well-being outcomes of papillary thyroid cancer patients (PTC) after surgery: a cross-sectional study.

This study was performed to evaluate the differences in oral function and psychological well-being between patients with PTC after the gasless transoral endoscopic thyroidectomy vestibular approach (gasless-TOETVA) and patients with PTC after open surgery. PTC patients who underwent radical surgery from May 2021 to August 2022 were included in this study. Postoperative data on oral function and psychological well-being, including the Oral Health Impact profile-14 (OHIP-14) and State-Trait Anxiety Inventory Form Y, were collected and analyzed. 212 patients were included in the analysis. Among them, 102 patients who received gasless-TOETVA were assigned to the gasless-TOETVA group, while the remaining 110 patients who underwent open surgery were categorized as the open group. Although the OHIP-14 score in the gasless-TOETVA group was higher than that of the open group from 6months to 1year after surgery (p = 0.012), the difference in OHIP-14 scores between the two groups disappeared 1year after surgery (p = 0.155). There were no differences between the gasless-TOETVA group and the open group in state-anxiety scores. However, the gasless-TOETVA group had significantly lower trait-anxiety scores than the open group at all follow-up time periods. Furthermore, within the gasless-TOETVA group, patients who were more than 1year post-surgery showed significantly increased trait-anxiety scores compared to those of patients who were less than 1year post-surgery (Δ = 3.4; p = 0.032). In contrast, the open group showed a decreasing trend in trait-anxiety scores, but there was no statistically significant difference between patients who had surgery less than 1year ago and those who had surgery more than 1year ago (Δ = - 2.2; p = 0.094). Gasless TOETVA had a temporary impact on oral function, but it did not alleviate the state of anxiety. Furthermore, we observed a significant increase in trait-anxiety scores among PTC patients who underwent gasless-TOETVA after 1 year.

Helping and Volunteering During COVID-19: Associations With Well-Being and Psychological Distress

IntroductionSalutogenic effects of volunteering and helping activities have been well recognized in the pre-COVID-19 era. This study examines associations between helping others as well as additional volunteer activities during the first wave of the COVID-19 pandemic and six psychological distress and well-being outcomes one year later. MethodsLongitudinal data collected between 2019 and 2021 were used. Analyses were based on data from 42,005 middle-aged and older adults from 27 European countries who participated in the Survey of Health, Ageing, and Retirement in Europe (SHARE) and two SHARE Corona Surveys. Prospective associations were examined using generalized estimating equations. A series of secondary analyses and the sensitivity of the associations to unmeasured confounding provided evidence for the robustness of results. All analyses were conducted in December 2022. ResultsHelping others outside one's home in the first wave of COVID-19 was associated with subsequent increased risks of depression and anxiety. It was concurrently associated with an increased probability of an uplifting, hope, and happiness-inducing experience. Engagement in volunteer activities conducted in addition to helping was found to be prospectively associated with higher probability of an uplifting experience, but not with depression and anxiety. These associations were independent of demographic and socio-economic characteristics, personality traits, prior quality of life and health history as well as pre-COVID-19 engagement in altruistic activities. ConclusionsHelping and volunteering during the COVID-19 pandemic likely led to positive experiences. However, a negative impact on psychological distress of the same activities was also noted.

Protocol of a cluster randomised trial of BodyKind: a school-based body image programme for adolescents

BackgroundPoor body image is prevalent among adolescents and associated with several negative outcomes for their physical and psychological health. There is a pressing need to address this growing public health concern, yet there are few evidence-informed universal programmes for older adolescents that address contemporary body image concerns (i.e., social media). BodyKind is a four lesson, school-based, teacher led, universal body image programme that incorporates empirically supported principles of cognitive dissonance, self-compassion, compassion for others and social activism, to support positive body image development. Building on previous pilot trials in the USA, this paper outlines the protocol for a cluster randomised control trial (cRCT) and implementation evaluation of the BodyKind programme which was culturally adapted for the Irish cultural context.MethodsWe aim to recruit 600 students aged 15-17 years in Transition Year (4th year) across 26 second-level schools in Ireland. Using minimisation, schools will be randomly assigned to receive BodyKind (intervention condition, n=300) or classes as usual (waitlist control, n=300). Teachers in intervention groups will receive training and deliver the programme to students over four weeks, at a rate of one lesson per week. Primary outcomes of body appreciation, body dissatisfaction and psychological wellbeing and secondary outcomes of self-compassion, compassion for others, body ideal internalisation, social justice motives and appearance-based social media use will be assessed at pre-, post- and 2 month follow up. Mediation and moderation analyses will be conducted to identify how and for whom the intervention works best. An implementation evaluation will assess the quality of programme implementation across schools and how this may influence intervention outcomes. Waitlist control schools will receive the programme after the 2-month follow up.ConclusionThis study will be the first to implement a cRCT and an implementation evaluation to assess the impact of this multicomponent school-based body image programme designed to support healthy body image development. If shown to be effective, BodyKind will have the potential to improve adolescent body image and wellbeing and inform efforts to implement sustainable and scalable programmes in schools.Trial registrationThe trial was retrospectively registered on 10/10/2023 on ClinicalTrials.gov NCT06076993.

Theorising the causal impacts of social frontiers: The social and psychological implications of discontinuities in the geography of residential mix

Until very recently, the question of how residents might be affected by the gradient of neighbourhood boundaries – whether these boundaries are abrupt or gradual – has remained largely absent from mainstream segregation research. Yet, theoretical and empirical findings emerging from recent studies suggest the impacts could be profound and far-reaching. This article seeks to provide a conceptual foundation for understanding such effects. We focus on the concept of ‘social frontiers’: spatial discontinuities in the geography of residential mix which occur when community boundaries are abrupt. Drawing on insights from cognate disciplines, we develop a theory of social frontier impacts that articulates their potential importance in limiting and shaping contact between neighbouring communities, exacerbating territorial conflict and ultimately affecting the psychological wellbeing and life course outcomes of those living at the frontier. We present our thesis as a series of propositions and corollaries, and reflect on the implications for empirical research.

Change in Patient-Centered Outcomes of Psychological Well-Being, Sleep, and Suicidality Following Treatment with Intravenous Ketamine for Late-Life Treatment-Resistant Depression

Change in Patient-Centered Outcomes of Psychological Well-Being, Sleep, and Suicidality Following Treatment with Intravenous Ketamine for Late-Life Treatment-Resistant Depression

Adjusting to college—Do ability beliefs and confidence in getting support matter for performance and mental health?

Entering college, students are required to adjust to a new academic and social environment. During the COVID-19 pandemic, social interactions with peers and faculty were limited to online settings and access to campus resources was restricted. Hence, students who entered college in fall 2020 began their freshman year under particularly challenging circumstances. We used data from two freshman cohorts, who started college either before or during the pandemic. We investigated to what extent mid-quarter academic and social adjustment (i.e., ability beliefs and confidence in getting support) predicted end-of-quarter performance, psychological distress, and satisfaction of freshman students. Results showed that students who started college during the pandemic were less confident they could get support by peers in the middle of their first quarter. Furthermore, students from the second cohort reported higher psychological distress and lower satisfaction with their adjustment at the end of their first quarter. Results showed that ability beliefs played an important role for end-of-quarter performance, whereas confidence in getting support was more relevant for psychological well-being outcomes in both cohorts.

Locally contextualized psycho-physiological wellbeing effects of environmental exposures: An experimental-based evidence

Geographically-distributed urban environment contexts affect human psychological wellbeing through the real-time interactions between individuals and their surroundings. Recent field experiments have become particularly interesting in using wearable devices for tracking episodic changes in wellbeing outcomes. However, most research primarily contribute to correlate unconscious physiological arousal with single environmental feature, ignoring the contextualized environment neural psychological effects at the brain level. This paper studies the effects of walking exposures to various urban environment contexts on neural physiological and psychological parameters relevant to mental health in women cohorts. We measure neural physiological parameters using a functional near-infrared spectroscopy (fNIRS) monitoring approach to detect brain activity variability during a journey-based field experiment, and perceived psychological wellbeing outcomes are measured through emotional questionnaires. A group of 10 healthy women walked across dense and diverse urban settings in Guangzhou, China. We have identified the beneficial effects of blue-green spaces and open spaces on psychological wellbeing, as well as their underlying neurophysiological mechanisms that exhibit localized context differentiation. Additional results quantify evidence in support of spatial typology and travel sequence-based uncertainties as underlying channels at work. Our study provide a walking-oriented investigation model of locally contextualized mental health effects, and expand explanatory method for walking mental health. It also suggests the importance of conceptualizing landscape complementarities in planning policies that help to improve the interaction between wellbeing and localized environmental exposures.

Interaction between DIO2 polymorphisms and LT4 treatment on psychological well-being outcomes and cardiovascular risk factors: a population-based cross-sectional study in uk biobank

Interaction between DIO2 polymorphisms and LT4 treatment on psychological well-being outcomes and cardiovascular risk factors: a population-based cross-sectional study in uk biobank