Psychological Stress Status Research Articles

Evaluation of the Obesity and Depression in Hypertensive Patients

Aim: Hypertension is one of the most common preventable causes of death in the world. In previous studies, the contribution of anxiety and depression symptoms in hypertension was investigated, but results were unclear. Obesity is one of the most important risk factors that leads to hypertension. In this study, we aimed to investigate the effect of body mass index (BMI) and Hamilton depression score on blood pressure in patients who comes to the Family Medicine Unit in Duzce University. Material and Methods: In this sectional study, 228 people diagnosed with obesity were included who admitted Duzce University family medicine unit. The relationship between BMI and Hamilton depression scores with systolic and diastolic blood pressure were studied in patients. Results: 200 of the patients (88%) enrolled in the study were women, and 28 of them (%12) were men. In our study, there was not significant effect of gender, occupational status, educational status and smoking on Hamilton depression score. Hamilton depression scores were analyzed in 228 patients, there was no depression in 182 patient (79.8%). Minor depression was detected in 35 patient (15.3%), major depresssion was found in 11 patients (4.8%). Increasing in The Hamilton depression score had a statistically significant effect on the increase in systolic blood pressure (p=0.017). Conclusion: According to these results, increasing BMI and Hamilton depression score were found to be associated with blood pressure increase. Holistic approaches to hypertensive patients are very important. Patient’s lifestyle, habits, current weight and psychological stress status should be examined in detail. This shows us that biopsychosocial holistic approach of family medicine unit to patient plays an important role in the prevention and treatment of hypertension.

Identification of psychological stress states based on joint analysis of multidomain features of skin conductance

Background and ObjectivePsychological stress identification generally uses a questionnaire with strong subjectivity. In contrast, skin conductance (SC) is not controlled by self-consciousness. Due to its correlation with psychological stress, SC has become the object of analysis for identifying psychological stress states. This study aimed to determine the effective features of SC and to establish an assessment model for psychological stress. MethodsIn this study, SC in resting and stress states was measured in 27 healthy subjects. Time-domain features (including general-time-domain and rise-and-fall-time features), frequency-domain features, and nonlinear features of the SC were extracted after pre-processing. Statistical differences in the features were analysed. Feature selection for the four feature types in the three domains was performed using the recursive feature elimination method. The optimal feature set was fed into support vector machine for classification. ResultsStatistical analysis results showed that all three feature domains contained features with significant statistical differences. When analysing single-domain features, the rise-and-fall-time features obtained the best classification results, with an accuracy of 86.73 %. In the joint analysis of two-domain features, combination of the frequency-domain and nonlinear features produced a maximum classification accuracy of 90.73 %. When three domain features were jointly analysed, a maximum classification accuracy of 94.36 % was achieved with the combination of the rise-and-fall-time, frequency-domain, and nonlinear features. ConclusionsThis study confirms the feasibility of joint analysis of the multidomain features of SC for identification of psychological stress states and provides methodological support for the real-time, objective, and quantitative evaluation of psychological stress.

MiR-10a, miR-15a, let-7a, and let-7g expression as stress-relevant biomarkers to assess acute or chronic psychological stress and mental health in human capillary blood

BackgroundPsychological stress, as an important cofactor in the development of many acute and chronic diseases, is crucial for general health or well-being, and improved markers are needed to distinguish situations of progressive pathological development, such as depression, anxiety, or burnout, to be recognized at an early stage. Epigenetic biomarkers play an important role in the early detection and treatment of complex diseases such as cancer, and metabolic or mental disorders. Therefore, this study aimed to identify so-called miRNAs, which would be suitable as stress-related biomarkers.Methods and ResultsIn this study, 173 participants (36.4% males, and 63.6% females) were interviewed about stress, stress-related diseases, lifestyle, and diet to assess their acute and chronic psychological stress status. Using qPCR analysis, 13 different miRNAs (miR-10a-5p, miR-15a-5p, miR-16-5p, miR-19b-3p, miR-26b-5p, miR-29c-3p, miR-106b-5p, miR-126-3p, miR-142-3p, let-7a-5p, let-7g-5p, miR-21-5p, and miR-877-5p) were analyzed in dried capillary blood samples. Four miRNAs were identified, miR-10a-5p, miR-15a-5p, let-7a-5p, and let-7g-5p (p < 0.05), which could be used as possible candidates for measuring pathological forms of acute or chronic stress. Let-7a-5p, let-7g-5p, and miR-15a-5p (p < 0.05) were also significantly higher in subjects with at least one stress-related disease. Further, correlations were identified between let-7a-5p and meat consumption (p < 0.05) and between miR-15a-5p and coffee consumption (p < 0.05).ConclusionThe examination of these four miRNAs as biomarkers using a minimally invasive method offers the possibility of detecting health problems at an early stage and counteracting them to maintain general and mental health.

Effect of nursing intervention based on continuity model on psychological stress state of patients with rheumatoid arthritis.

To explore the effect of nursing intervention based on continuity model on psychological stress state of patients with rheumatoid arthritis (RA). A total of 128 patients with RA in our hospital from January 2015 to January 2017 were selected and divided into 2 groups by random number table method, 64 cases in each group. The control group received routine nursing, and the observation group received nursing intervention based on continuity model. The physiological function recovery, psychological stress, negative psychology, trait coping style and quality of life were compared between the 2 groups. Compared with the control group, the first time to get out of bed, the time to subside swelling of upper limb and the length of hospital stay in the experimental group were significantly shorter, the sleep time was significantly longer, and the visual analog scale score was significantly lower in the experimental group (all P < .05). After receiving nursing intervention, the psychological stress scores of somatizations, anxiety and depression of all patients were significantly lower than before nursing, and the above scores of the observation group were significantly lower than those of the control group (all P < .05). After nursing, the positive coping score, negative coping score and quality of life score of all patients were significantly higher than those before nursing, and the above scores of the observation group were significantly higher than those of the control group (all P < .05). Nursing intervention based on continuity model can promote the recovery of physical function, improve psychological stress and negative emotions, and improve the quality of life of patients with RA, which is worthy of clinical application.

Psychological Stress in Parents of Children with Atopic Dermatitis: A Cross-sectional Study from the Korea National Health and Nutrition Examination Survey

Atopic dermatitis is a chronically relapsing inflammatory skin condition that has profound impacts on quality of life of patients and their family. The aim of this study is to investigate the psychological stress in parents of children with atopic dermatitis in Korea, using data from the Korean National Health and Nutrition Examination Survey (KNHANES). This cross-sectional study included parents of participants under 19 years of age (970 with atopic dermatitis and 5,733 without atopic dermatitis after excluding those who meet the exclusion criteria) from the 2009 to 2012 KNHANES. The psychological stress state was evaluated with the following four questionnaire items: self-perception of stress, depressed mood, suicidal ideation, and diagnosis of depression by a physician. After adjusting for age, gender, education level, occupation, and marital status, logistic regression analyses indicated that mothers of children with atopic dermatitis had a higher frequency of stress perception (adjusted odds ratio (aOR) 1.46 (95% confidence interval (95% CI) 1.22-1.74), p < 0.01) and suicidal ideation (aOR 1.40 (95% CI 1.1-1.79), p < 0.01) than those without atopic dermatitis. In contrast, fathers of children with atopic dermatitis did not show a significant difference in all items compared with those of children without atopic dermatitis. Understanding the psychological stress in parents of children with atopic dermatitis is important for clinicians, since evaluation, management and support for parents, especially mothers, of children with atopic dermatitis are required.

Psychological stress recognition from heart rate variability parameters based on field programmable gate arrays.

Psychological stress is a big threat to people's health. Early detection of psychological stress is important. The design of a stress recognition device based on the ECG (electrocardiograph) signal is presented in this paper. The device features intelligence, precision, portability, fast response, and low power consumption. In the design, the ECG signals are acquired by the AD8232 ECG module and processed by a low power consumption FPGA (Field Programmable Gated Array) development board PYNQ-Z2. Meanwhile, a modified Deep Forest model named Aw-Deep Forest (Adaptive Weight Deep Forest) is proposed. The Aw-Deep Forest has better performance than the Deep Forest model because it improves the fitting quality of the forests. By implementing the Aw-Deep Forest model on the FPGA, the device can assess people's state of psychological stress by analyzing the HRV (heart rate variability) parameters from ECG data. This paper mainly introduces the detailed process of ECG signal collecting, filtering, analog signal to digital signal conversion, HRV parameter analysis, and psychological stress recognition with Aw-Deep Forest. The final accuracy is 81.39%.

Portraying improvement in the management of chronic pain: A multi-modal longitudinal interpretative phenomenological analysis study.

Chronic pain is a common, profoundly disabling and complex condition whose effects on identity may explain the distress experienced by those affected by it. This paper concerns a study exploring how the relationship with pain and sense of self evolved following participation in a pain management program (PMP). Participants were interviewed at three timepoints: before attending a PMP, 1 month after the PMP and 6 months after the PMP. To facilitate a deep experiential description of pain and its effects, interviews were guided by participant-generated drawings of pain and Self. Interviews and drawings were analyzed longitudinally using interpretative phenomenological analysis. The evolving experience of participants was outlined through different trajectory types. Here we describe the upward and positive trajectory of three female participants who were able to regain control over their lives. From a state of psychological stress where pain was represented as an aggressive and oppressive presence, participants' drawings, their narratives and indeed their lives, changed for the best. Pain stopped being the main feature, they were able to integrate it into their lives, make important changes and find a new balance. The results demonstrate the idiosyncratic nature of chronic pain and offer a nuanced account of its links to the lifeworld of those living with it.

Effects of the Concept of Fast-Track Surgery Combined with Empathic Nursing on Perioperative Complication Prevention and Postoperative Recovery of Gynecological Malignant Tumor Patients.

Objective This study is aimed at exploring the effects of the concept of fast-track surgery (FTS) combined with empathic nursing on perioperative complication prevention and postoperative recovery of gynecological malignant tumor patients. Methods A total of 180 patients with gynecological malignant tumor treated by surgery in our hospital from September 2018 to October 2021 were randomly divided into three groups: group A, group B, and group C, with 60 patients in each group. Group C was given conventional nursing intervention, group B was given FTS intervention, and group A was given FTS intervention combined with empathic care. Psychological stress state (systolic blood pressure, diastolic blood pressure, and heart rate), postoperative recovery indicators (time of first anal exhaust, time of first defecation, time of getting out of bed, and length of postoperative hospital stay), postoperative complications, and psychological state (Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS)) levels of patients in the three groups were compared. Results Systolic blood pressure, diastolic blood pressure, and heart rate in group A were lower than those in group B, and those in group B were lower than those in group C (all P < 0.05). The time of first anal exhaust, time of first defecation, time of getting out of bed, and postoperative hospital stay in groups A and B were shorter than those in group C (all P < 0.05).The incidence of postoperative complications in groups A and B was 8.33% and 8.33%, respectively, lower than 23.33% in group C (both P < 0.05). SAS and SDS scores of group A were lower than those of groups B and C after intervention (all P < 0.05). Conclusion The concept of FTS combined with empathic nursing is beneficial to reduce the stress response of patients with gynecological malignant tumor before surgery, reduce the risk of postoperative complications, improve patients' mood, and speed up the rehabilitation process of patients.

Effect of Kangaroo Mother Care on the Psychological Stress Response and Sleep Quality of Mothers With Premature Infants in the Neonatal Intensive Care Unit.

ObjectiveTo investigate the effect of kangaroo mother care on the psychological stress response and sleep quality of mothers with premature infants admitted to the neonatal intensive care unit (NICU).MethodsA randomized controlled design was used to recruit participants. The study recruited 126 mothers of premature infants in the NICU from January 2019 to January 2020. The participants were divided into the experimental and control groups according to the random number table method (63 mothers per group). The control group was managed with conventional premature infant treatment, nursing programme, and discharge education, whereas the experimental group was managed with a 4-week kangaroo mother care intervention. The psychological stress state and sleep status of mothers with preterm infants in both the groups were evaluated using the Symptom Check List 90 (SCL-90) and Assens Insomnia Scale (AIS).ResultsAfter the intervention, the total SCL-90 score and factor scores such as coercion, interpersonal relationships, depression, anxiety, hostility and additional factors, were lower in the experimental group than those in the control group (P < 0.05). The total AIS score and the items such as night waking, total sleep time, total sleep quality, daytime mood and daytime body function were lower in the experimental group than those in the control group (P < 0.05).ConclusionsThe Kangaroo mother care approach can relieve adverse psychological stress and improve the sleep status of mothers of NICU premature infants after mother-infant separation. It can be promoted and used in mothers of premature infants in the NICU to enhance physical and mental health.

A qualitative study exploring barriers and facilitators to establishing nurse-led, multidisciplinary psychological care for trauma patients: experiences from doctors and nurses

BackgroundTrauma patients are often in a state of psychological stress, experiencing helplessness, sadness, frustration, irritation, avoidance, irritability and other adverse emotions. Doctors and nurses are at the forefront of caring trauma patients and they play a crucial role in psychological supports and mental health care. However, few qualitative studies had based on the framework of the Theory of Planned Behavior (TPB) to explore the experiences in providing psychological care for trauma patients. We examined attitudinal, normative, and control beliefs underpinning medical staffs’ decisions to perform psychological care.MethodA qualitative study of in-depth semi-structured interviews was conducted among 14 doctors and nurses engaging in trauma care. The participants came from six tertiary hospitals in Chongqing, China. Data analysis was performed using the approach of Colaizzi. According to the framework of TPB, the researchers identified and summarized the themes.ResultsImportant advantages (mutual trust, patients' adherence and recovery), disadvantages (workload, short-term ineffective, practice unconfidently), referents (supportive: managers, patients, kinsfolk, nursing culture; unsupportive: some colleagues and patients), barriers (insufficient time or energy, resources situations), and facilitators (access to psychologist, training/education, reminders) were identified. Some demands, such as training diversity, multidisciplinary cooperation and families' support, reflected by doctors and nurses were important for them to carry out psychological care.ConclusionAccording to the TPB, this article explored the internal and external promotion and hindrance factors that affecting the intentions and behaviors of doctors and nurses in implementing psychological care for trauma patients. We also focused on the experience and demands of health professionals in conducting psychological care, which could provide references for managers to formulate corresponding psychological care procedures and norms.

Can physical activity be simplified for health benefit?

Physical activity (PA) offers protective benefits against at least 25 chronic conditions including psychological stress. The health benefits of PA may be largely attributed to improvements in cardiorespiratory fitness (CRF). However, current guidelines based on PA duration and intensity are controversial, and both are prone to measurement error. We designed a New Zealand specific physical activity frequency and type (PAFT) question, our aims were to examine if PAFT could predict CRF and psychological stress status. In experiment one, 20 subjects who regularly perfumed vigorous type PA completed PAFT prior to World Health Organization (WHO) recommended cardiorespiratory fitness (CRF) (VO2Peak) estimation in a controlled exercise laboratory. In experiment two, 81 subjects completed PAFT and a reliable validated measure of stress (the ten-item Perceived Stress Scale (PSS-10)). Vigorous type PA frequency had a strong association (R2=0.71, p<0.01) with VO2Peak and was also the most significant (p<0.01) predictor of low stress. A simple quick PA type and frequency question predicts CRF and stress status. PA duration and intensity are not required to estimate the health benefits of PA. Two vigorous type PA activities per week can be recommended as a minimum PA dose to decrease risk of stress in similar populations.

The Relationship Of Depression-Anxiety Inspection And Hypertension In Newly Diagnosed Young Hypertensive Patients

Aim: Hypertension (HT) is a very important risk factor for cerebrovascular, renal and various vascular diseases, especially&#x0D; cardiovascular diseases. It is seen in almost 1/3 of the adult world population and its incidence is gradually increasing.&#x0D; 95% of HT is essential and various reasons are emphasized in the etiology. Conditions that cause psychological stress,&#x0D; especially depression; Although the relationship between them is not clear, it was seen as a risk factor for HT. Because&#x0D; they will live with HT for a long time, early diagnosis and treatment is important, especially in young patients. Predisposing&#x0D; factors should also be taken into account in treatment. Anxiety and depression, which are called increased sympathetic&#x0D; activity in young people, can be a trigger for HT. In this study, we wanted to investigate the susceptibility to depressionanxiety in newly diagnosed young hypertensive patients. According to the result, we thought that we could make new&#x0D; recommendations in the treatment of HT.&#x0D; Materials and Methods: 175 patients under the age of 45 with newly diagnosed HT and 125 individuals under 45 without&#x0D; any health problems were included in the study. Those diagnosed with HT with secondary reasons and those with chronic&#x0D; diseases such as coronary artery disease (CAD), diabetes mellitus (DM), chronic renal failure (CRF), congestive heart failure&#x0D; (CHF) were excluded from the study. Testing was performed with the Hospital Depression Anxiety Scale (HDAS). In this test&#x0D; for both anxiety and depression; 0-7 points were considered normal, 8-10 points were considered borderline, and over 11&#x0D; points were considered abnormal.&#x0D; Results: When the results were evaluated, there was no difference between the groups in terms of age, gender, and&#x0D; routine biochemical tests. Both depression and anxiety scales were found to be significantly higher in the HT group. In&#x0D; young hypertensive patients, we have seen that HT and depression-anxiety frequently coexist.&#x0D; Conclusion: In this case, we should definitely examine the psychological stress states of young patients we diagnosed with&#x0D; HT. It would be appropriate to refer patients who we think may have depression and anxiety for psychological support and&#x0D; treatment. When psychological problems are treated, HT may improve without the need for antihypertensive treatment.&#x0D; Thus, we can develop new approaches in HT treatment.

Online Public Rumor Engagement Model and Intervention Strategy in Major Public Health Emergencies: From the Perspective of Social Psychological Stress.

During major public health emergencies, a series of coupling problems of rumors getting out of control and public psychological imbalance always emerge in social media, which bring great interference for crisis disposal. From the perspective of social psychological stress, it is important to depict the interactive infection law among distinct types of rumor engagers (i.e., advocates, supporters, and amplifiers) under different social psychological stress states, and explore the effectiveness of rumor intervention strategies (i.e., hindering and persuasion) from multiple dimensions, to scientifically predict the situation of public opinion field and guide the public to restore psychological stability. Therefore, this paper constructs an interactive infection model of multiple rumor engagers under different intervention situations based on a unique user-aggregated dataset collected from a Chinese leading online microblogging platform (“Sina Weibo”) during the COVID-19 in 2020. The simulation result shows that (1) in the period of social psychological alarm reaction, the strong level of hindering intervention on the rumor engagers leads to more serious negative consequences; (2) in the period of social psychological resistance, the persuasion and hindering strategies can both produce good outcomes, which can effectively reduce the overall scale of rumor supporters and amplifiers and shorten their survival time in social media; (3) in the period of social psychological exhaustion, rumor intervention strategies are not able to have a significant impact; (4) the greater the intensity of intervention, the more obvious the outcome. Experimental findings provide a solid research basis for enhancing social psychological stress outcomes and offer decision-making references to formulate the rumor combating scheme.

A Multi-feature and Time-aware-based Stress Evaluation Mechanism for Mental Status Adjustment

With the rapid economic development, the prominent social competition has led to increasing psychological pressure of people felt from each aspect of life. Driven by the Internet of Things and artificial intelligence, intelligent psychological pressure detection systems based on deep learning and wearable devices have acquired some good results in practical application. However, existing studies argue that the psychological stress state is influenced by the current environment. They put much attention on the momentary features but ignore the dynamic change process of mental status in the time dimension. Besides, the lack of research in the general laws of psychological stress makes it difficult to quantitatively evaluate the stress status, resulting in the inability to perceive the stress state of users effectively. Thus, this article proposes an evaluation mechanism of psychological stress for adjusting the mental status of users. Specifically, we design a multi-dimensional feature space and a time-aware feature encoder, which integrate various stress features and capture time characteristics of stress state change. Moreover, a novel mental state model is proposed, which uses the pressure features with time characteristics to evaluate the pressure stress level. This model also quantifies the internal relationship between pressure features. Last, we establish a practicable testbed to demonstrate how to evaluate and adjust mental state of users by the proposed evaluation mechanism of psychological stress.

Psychometric properties of the Tamil version of Perceived Stress Scale among diabetes mellitus patients in Puducherry, South India.

Perceived Stress Scale (PSS), developed in 1983, is one among the widely used global scales to assess the perceived psychological stress status. Hence, our study aimed at developing a Tamil version of THE 10-item PSS (TPSS-10) and assess its construct validity and internal consistency among patients with diabetes in Puducherry, South India. We translated the TPSS-10 by language experts and pilot-tested the sample with a subsample of diabetes patients. The finalized version of TPSS-10 was administered to 117 Tamil-speaking diabetic patients availing services from the rural health center in Puducherry, South India. Construct validity was assessed using the exploratory factor analysis (EFA) and the principal component analysis (PCA). A confirmatory factor analysis (CFA) was also done to obtain the goodness-of-fit. Reliability of questionnaire was evaluated by Cronbach's alpha. Two factors were obtained with Eigenvalues of 4.61 and 2.16. Both factors explained 67.8% of the total variance. The two-factor model assessed by CFA found a χ2 value of 714.99 (P < 0.001). Goodness-of-fit revealed acceptable comparative fit indices (0.93). The reliability coefficient (Cronbach's alpha) for complete TPSS-10 was 0.86, indicating good internal consistency. Our study concludes that the TPSS-10 questionnaire is internally valid and consistent with good reliability coefficient after its administration to Tamil-speaking urban diabetic patients in order to measure perceived stress. However, further research is warranted to content-validate the tool with a standard diagnostic instrument.

Research on Prediction Algorithm of Employees’ Psychological Stress Based on Multifeature Fusion

A multifeature fusion-based enterprise employee psychological stress prediction algorithm is suggested to address the concerns of low prediction accuracy, long duration, and poor results in current psychological stress prediction approaches. Examine ECG signal generation and properties, as well as the notion and causes of heart rate variability. The ECG signal is gathered according to the psychological stress reaction mechanism, and the digital filter is utilized to filter and preprocess the noise interference of the ECG signal. The linear discriminant analysis algorithm extracts the time domain linear features, frequency domain linear features, and nonlinear features of the ECG signal and then selects the ECG signal characteristics. D-S evidence theory is used to fuse the time domain linear characteristics, frequency domain linear characteristics, and nonlinear characteristics of the ECG signal, construct the psychological stress prediction model, obtain the final result of psychological stress state prediction, and realize the psychological stress prediction of enterprise employees, all based on multifeature fusion technology. The results of the experiments reveal that the suggested algorithm has a greater predictive effect on employee psychological stress, allowing it to enhance forecast accuracy and reduce prediction time.

ECG-based biometric under different psychological stress states

Background and objectiveIn recent years, people have been exploring methods for biometric identification through electrocardiogram (ECG) signals. Under the same psychological pressure state, biometric identification through ECG signals is a traditional verification method. However, ECG signals are affected by changes in psychological stress, and ECG-Based biometric under different psychological stress states are still challenging. In this paper, we propose a method combining manual and automatic features for ECG-based biometric under different psychological stress states. And propose a new indicator Stress Classification Coefficient (SCC) that assesses the effect of different psychological stress on heart rate variability (HRV) features. MethodsIn our method, we obtain manual features to be a three-step process: first, HRV features obtained from the ECG signals. Second, based on HRV features, the mental state of the experimental subjects is assessed by using the Gaussian mixture model (GMM). Finally, use cluster centers to process the original HRV features to reduce the Stress Classification Coefficient (SCC). Also, the one-dimensional convolutional neural network is constructed to automatically extract the implied features of ECG signals. Finally, the manual feature and the automatic feature are combined, and the final recognition result is obtained through the support vector machine (SVM) model. The major attribute of the proposed method is that it can perform ECG biometric under different psychological stress states. The combination of manual and automatic features expands the application scenarios of ECG-based biometric. ResultsBased on this method, we used the Montreal stress model with calculation experiment in the laboratory to induce stress on 23 healthy students (10 women and 13 men, aged 20–37), and obtain their ECG signals under different stress conditions. Through this method to recognize the above data, an average recognition rate of more than 95% can be achieved, the average F1 score is 0.97. ConclusionsThe proposed method in this article is a promising approach to deal with the effects of different psychological stresses on ECG-Based biometric. It provides the possibility of ECG-Based biometric under different psychological stress.

2019nCoVAS: Developing the Web Service for Epidemic Transmission Prediction, Genome Analysis, and Psychological Stress Assessment for 2019-nCoV.

Since the COVID-19 epidemic is still expanding around the world and poses a serious threat to human life and health, it is necessary for us to carry out epidemic transmission prediction, whole genome sequence analysis, and public psychological stress assessment for 2019-nCoV. However, transmission prediction models are insufficiently accurate and genome sequence characteristics are not clear, and it is difficult to dynamically assess the public psychological stress state under the 2019-nCoV epidemic. Therefore, this study develops a 2019nCoVAS web service (http://www.combio-lezhang.online/2019ncov/home.html) that not only offers online epidemic transmission prediction and lineage-associated underrepresented permutation (LAUP) analysis services to investigate the spreading trends and genome sequence characteristics, but also provides psychological stress assessments based on such an emotional dictionary that we built for 2019-nCoV. Finally, we discuss the shortcomings and further study of the 2019nCoVAS web service.

A Study on Occupational and Psychological Stress Status and Countermeasures of “High-Level Talents” in Hainan Provincial People’s Hospital

Objective: To investigate and contrastively analyze the occupational and psychological pressure of “high-level talents” and department directors in Hainan Provincial People’s Hospital, so as to provide countermeasures for the development and management of “high-level talents” engaged in teaching, scientific research and clinical work. Methods: Literature study, expert consultation, Occupational Stress Scale (OSI-R) and PCL-C were used. Results: The research shows that “high-level talents” have different individual stress response with different educational background. Comparing the individual stress response with different educational background, the “business stress” of “high-level talents” with master’s degree is significantly different from that of doctor’s degree (t = 0.64, P P P < 0.05). Conclusion: Scientific and technological innovation is inseparable from excellent innovation team, and excellent innovation team is inseparable from excellent leading talents. Only by paying attention to “high-level talents”, can we take the path of independent innovation with Chinese characteristics, build a free trade pilot zone for the whole island of Hainan, provide the demand for talents construction in Hainan medical strategic transformation, improve the competitiveness of the hospital to the greatest extent, and better achieve the grand goal of building a research- oriented hospital.

24시간 수면박탈이 운동욕구 및 스트레스호르몬에 미치는 영향

The purpose of this study was to confirm the effect of 24-hour sleep deprivation on exercise desire and stress hormone changes. To this end, male college students attending a university in Gyeonggi-do were divided into an experimental group, who was deprived of sleep for 24 hours, and a control group, who led daily life. In addition, since the psychological state of the study subjects could indirectly affect hormones, the effect of the mediator was controlled as much as possible through the questionnaire for personal problems, diseases, and recent psychological stress states. Based on this, the following conclusions were drawn. First, the experimental group and the control group showed a significant interaction effect in the physical exercise desire, and the psychological exercise desire also showed a significant interaction effect. In addition, it showed a significant interaction effect in overall exercise desire. Second, among the stress hormones of the experimental group and the control group, cortisol had a significant interaction effect, and norepinephrine had a significant interaction effect. On the other hand, in growth hormone, there was a tendency toward the mean, but no statistically significant interaction effect was observed.