Spherical brown cleistothecia (100 to 300 μm in diameter) of Scedosporium containing oblong brown ascospores were observed in Fig. 1B and C. Cleistothecia are the hallmark of the sexual stage (teleomorph) of this filamentous fungus, which belongs to the phylum Ascomycota. The teleomorph is also known under the genus name Pseudallescheria (1). Strains isolated from clinical samples rarely produce these sexual reproductive structures, but they can be obtained from culture, particularly on nutrient-poor media such as cornmeal agar or potato dextrose agar, after 2 to 3 weeks of growth (1). The development of cleistothecia in the sinus cavity could be correlated with a less favorable environment for fungus growth. The hyphae of this mold are hyaline, and the brownish black color of the colony is due to the brown color of conidia and not to melanin production (2); hence, the Fontana-Masson staining should be considered negative (1). Microscopy does not distinguish between Scedosporium species. Pseudallescheria ellipsoidea was identified by sequencing a partial region of the beta-tubulin gene (GenBank accession number MT821950; 97.86% match with the type strain P. ellipsoidea CBS 418.73 [KT008449]) (see Fig. S1 in the supplemental material) (3). This species belongs to the Scedosporium apiospermum species complex, which also comprises Pseudallescheria angusta, S. apiospermum, Scedosporium boydii, and Pseudallescheria fusoidea.