This paper reviews the latest technological developments in contemporary radiation therapy equipment and their significance in clinical applications. It begins with an introduction to the basic principles and historical evolution of radiation therapy, followed by a detailed analysis of common types of radiation therapy equipment, including linear accelerators, Gamma Knives, proton therapy equipment, and heavy ion therapy equipment. For each type, the paper conducts an in-depth comparative analysis of their technical characteristics, covering aspects such as performance, accuracy, therapeutic efficacy, safety, side effects, cost, and maintenance. The paper then explores the latest trends in radiation therapy technology development, such as image-guided radiation therapy (IGRT), intensity-modulated radiation therapy (IMRT), stereotactic radiosurgery (SRS), and adaptive radiation therapy (ART), highlighting their clinical applications and potential through case studies. Finally, the paper looks forward to future development directions in radiation therapy technology, including the research and development of new equipment and technologies, trends in personalized treatment, and the prospects for artificial intelligence in radiation therapy. The aim of this paper is to provide comprehensive references and guidance for research and clinical practice in radiation therapy equipment.