Prospective Relationship Research Articles

The relationship between depressive symptoms and coping style on asthma outcomes in older adults.

To examine the impact of coping styles in older adults with asthma on the prospective relationship between depressive symptoms and asthma outcomes, and how their perceptions of social support influenced their coping styles. Adults 60 and over with asthma were recruited and interviewed about their experiences of asthma, depression, and other psychosocial factors over three time points (Baseline, 6-month, and 12-month visits). Structural equation models examined the mediating roles of coping styles in the relationship between depressive symptoms (assessed by BDI-II) and asthma outcomes (i.e., asthma control, asthma quality of life, asthma-related distress, asthma-related hospitalizations, and oral corticosteroid use) and the mediating role of perceived social support in the relationship between depressive symptoms and coping style. 455 participants were included in this study. Overall, 33.9% of the study population self-identified as Black and 32.8% as Hispanic. Depressive symptoms at baseline predicted less spiritual coping at 6months (β = - 0.15, p = 0.03), more negative coping at 6months (β = 0.44, p < .0001), and worse asthma outcomes at 12months (β = 0.31, p < .0001). None of the coping styles significantly mediated the relationship between depressive symptoms and asthma outcomes. Perceived social support mediated the relationship between depressive symptoms and positive coping, such that more depressive symptoms predicted less perceived social support, which in turn resulted in less positive coping engagement (β = - 0.06, p = 0.03). This study demonstrates that in older adults with asthma depressive symptoms impact perceived social support, coping strategy selection (including spiritual coping), and subsequent asthma outcomes.

Emotion Regulation Moderates the Prospective Association between ERN and Anxiety in Early Adolescence: An Age-Specific Moderation of Cognitive Reappraisal but not Expressive Suppression.

The increasing prevalence of anxiety problems during adolescence underscores the importance of a better understanding of the development of anxiety. Existing literature has documented a prospective association between error responsivity - characterized by the ERP component of error-related negativity (ERN) - and anxiety in youths. However, it remains unclear to what extent the ERN-anxiety relationship may be moderated by emotion regulation, another attribute critical to the development of anxiety. We collected two waves of data from 115 healthy early adolescents (66 girls; Mean age/SD at T1 = 11.00/1.16 years), approximately one year apart. Participants completed an EEG Go/No-Go task and reported on their anxiety symptoms at T1 and T2; they also reported on their emotion regulation tendencies (i.e., cognitive reappraisal [CR] and expressive suppression [ES]) at T2. The ERN was quantified via a principal component analysis. We found a moderating effect of ES on the ERN-anxiety association. Specifically, a larger T1 ERN predicted greater T2 anxiety symptoms for youths with higher, but not lower, ES. Interestingly, the moderating effect of CR on the ERN-symptom association was conditioned on age. Among older youths (upper age tercile) only, the association between T1 ERN and T2 symptoms was significant for those with lower, but not higher, CR. These findings contribute novel evidence on the moderating effect of emotion regulation on the prospective ERN-anxiety relationship in early adolescence. Our results elucidate age-specific patterns in the moderating effect of CR. Future studies can leverage these findings to tailor emotion regulation interventions for youths of different ages.

High hemoglobin-to-red cell distribution width ratio reduces adverse events in patients with pacemaker implantation

BackgroundThe prognostic significance of the hemoglobin-to-red blood cell distribution width (Hb/RDW) ratio in patients undergoing pacemaker implantation (PMI) remains uncertain. Our study aimed to explore the prospective relationship between the Hb/RDW ratio and the risk of major cardiovascular events (MCEs) in Chinese patients with PMI.MethodsA total of 595 patients with permanent PMI were enrolled. Patients were divided into the high-Hb/RDW (≥ 9.1 g/L per percent) and the low-Hb/RDW (< 9.1 g/L per percent) groups according to the levels of the Hb/RDW ratio using the receiver operating characteristic curve. The primary outcome was the composite MCEs including heart failure hospitalization, myocardial infarction, stroke, and all-cause death, presented as hazard ratios (HR) with 95% confidence intervals (CI) estimated by the Cox Proportional Hazards models, propensity score (PS) adjusted, and inverse probability weighting (IPW) analyses, respectively.ResultsDuring the median 2-year follow-up period, 95 (16%) MCEs were identified among the 595 patients with PMI Patients with a high Hb/RDW ratio exhibited a lower risk of MCEs compared to those with a low Hb/RDW ratio (adjusted HR: 0.456; 95% CI: 0.376–0.848). In additional analyses with different statistical models, the multivariate-adjusted HR was 0.592 (95% CI: 0.380–0.920) for the PS-adjusted analysis and 0.444 (95% CI: 0.271–0.729) for the IPW, respectively. There were no interactions between subgroups and Hb/RDW in our analysis.ConclusionHigh levels of the Hb/RDW ratio were linked to a lower risk of composite MCEs. The Hb/RDW ratio was a better predictor of MCEs than Hb or RDW alone.

Prospective relationship between family screen time rules, obesogenic behaviours, and childhood obesity.

Family screen use rules (FSRs) could plausibly protect against the development of childhood obesity, although the mechanisms underlying these protective effects remain largely unexplored. This research aimed to investigate prospectively the associations between exposure to FSRs at age 24 months, obesogenic behaviours (excessive screen time and short sleep duration) at age 45 months, and obesity at age 54 months. Additionally, a model proposing the mediating role of obesogenic behaviours in the association between FSRs and childhood obesity was tested. Data were obtained from 5733 children and their mothers participating in the 'Growing Up in New Zealand' study. Logistic regressions examined the association between three FSRs (rules on quality, quantity and timing of screen time, and different numbers of FSRs), obesogenic behaviours, and childhood obesity. Structural equation modelling (SEM) was applied to assess the potential mediating roles of obesogenic behaviours in the association between FSRs and zBMI. Neither exposure to individual nor all three FSRs was significantly associated with lower odds of obesity. However, protective effects of FSRs were observed concerning obesogenic behaviours. Exposure to individual or all three FSRs correlated with reduced odds of not meeting screen time and sleep duration recommendations. SEM analysis indicated no direct association between FSRs and zBMI; nevertheless, a significant indirect association was identified through the mediation of obesogenic behaviours. These findings suggest the potential benefits of promoting the adoption of FSRs as a promising population-based strategy to enhance child health behaviours and mitigate the risk of childhood obesity.

The prospective relationship between anxiety symptoms and eating disorder symptoms among adolescents: a systematic review and meta-analysis of a bi-directional relationship.

Anxiety symptoms and eating disorder symptoms commonly co-occur in adolescents. However, there is divergent evidence on the prospective relationship between the two factors. This systematic review and meta-analysis summarises the existing literature on the prospective and bi-directional relationship between anxiety symptoms and eating disorder symptoms in adolescence. A systematic search across six databases was conducted on the 11th June 2024. Studies were included if they assessed the prospective relationship between anxiety symptoms and eating disorder symptoms, or vice versa, in adolescence. 19,591 studies were screened, of which 54 studies met inclusion criteria and were included in the full review. Four meta-analyses were conducted. Anxiety symptoms were associated with subsequent eating disorder symptoms, increases in eating disorder symptoms, and higher odds of eating disorders, including their onset. Conversely, eating disorder symptoms were associated with subsequent anxiety symptoms, increases in anxiety symptoms, and higher odds of subsequent anxiety disorders. Current evidence suggests that anxiety symptoms and eating disorder symptoms do not merely co-occur during adolescence, but are prospectively and bi-directionally linked. Further research is needed to understand the underlying mechanisms of this relationship, as well as individual differences in symptom trajectories.

Worsening sleep predicts next-week suicidal ideation in a high-risk adolescent outpatient treatment sample.

Suicidal thoughts and behaviors often onset during adolescence, constituting a major public health concern. Despite rising rates in youth, psychotherapeutic and pharmacological treatment outcomes remain meager, indicating a need to identify modifiable risk factors. Experts suggest sleep may serve as a promising clinical indicator of risk and treatment progress, yet few studies have examined acute temporal associations between sleep and suicidal ideation. Participants were depressed and suicidal adolescents (age 13-19, n = 311) attending an intensive outpatient program (IOP). Patients completed weekly self-report assessments of sleep, depression, and suicidal ideation throughout IOP, with an average of 5 assessments over 30 days. Greater overall sleep difficulties, as well as within-person increases in sleep difficulties, were predictive of greater depression severity and suicidal ideation at subsequent assessments, above and beyond previous levels of symptoms. The reverse associations were not found. Inclusion of within-person changes in sleep difficulties significantly improved model fit compared to inclusion of overall sleep difficulties alone. This study provides additional evidence for a prospective relationship between worsening sleep difficulties and suicidal ideation in an IOP youth sample. Worsening sleep may be an important clinical indicator of subsequent depression and suicide risk among adolescents in treatment.

The relationship between young people, social media use and alcohol use: A prospective cohort study

Background and aimsSocial media use is now a significant part of modern daily life. Little is known about how social media impacts young peoples’ drinking behaviours and drinking-related consequences. This cohort study aims to explore the prospective relationship between social media use and future drinking. Methods1473 alcohol naïve young people, who at Wave 5 (aged 12–13 years) reported no lifetime alcohol use, were included (social media use, peer alcohol use, and covariates were also reported at Wave 5). At Wave 8 (aged 17–18 years), participants reported alcohol use outcomes, including age of drinking initiation, past month and past week risky consumption (>10 drinks/week), and problem drinking (alcohol-related troubles, injuries, and fights). ResultsAfter controlling for factors known to be associated with alcohol use in young people and applying a conservative significance level (α =.01), results revealed that children who engaged in almost daily social media use at ages 12–13 later reported a younger age of drinking onset (β = −0.56, 95 % CI = −0.74, −0.39, p <.001) and greater problem drinking (β = 0.48, 95 % CI = 0.13, 0.83, p =.008) at ages 17–18, compared to those who never used social media at ages 12–13. Early social media use was not associated with odds of subsequent past-month alcohol use or risky alcohol consumption. ConclusionYoung peoples’ social media use was associated with future drinking behaviours, prompting the need for preventative measures to acknowledge the salient impacts of social media.

Prospective associations between early adolescent reward functioning and later dimensions of psychopathology.

Individual differences in reward functioning have been associated with numerous disorders in adolescence. Given relations with multiple forms of psychopathology, it is unclear whether these associations are disorder specific or reflective of shared variance across multiple disorders. In a sample of adolescents (N = 418), we examined associations between neural and self-reported indices of early reward functioning (age 12) with different levels of a hierarchical psychopathology model assessed later in adolescence (age 18). We examined whether prospective relationships between reward functioning are specific to individual disorders or better explained by transdiagnostic dimensions. We found modest results for prospective associations between reward indices and different dimensions of psychopathology, with most significant associations not surviving correction for multiple comparisons. We discuss the benefits and limitations of the modeling approach used to examine dimension-specific associations that future work can build on. Overall, more work is needed to better understand how reward functioning is specifically associated with different forms of and hierarchical levels of psychopathology. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Longitudinal association between adolescent sexual identity and sleep quality: The mediating roles of peer victimization and perceived social support

ObjectiveDespite growing evidence of disparities in sleep quality between sexual minoritized and heterosexual youth, the reasons for these disparities are not well understood. LGBQ+ adolescents often experience challenging peer relationships, which could negatively impact their sleep quality. The current study examined the prospective relationship between sexual minority status and sleep quality over 12months and evaluated whether peer victimization and social support at 6months mediated this relationship among adolescents. MethodsThis study involved a secondary analysis of data from a community sample of 800 adolescents (57.5% female; Mage=14.42years, SD=0.83). Data were collected using web-based surveys over 12months with three time-points: baseline, 6-, and 12-month. ResultsApproximately 19.4% of adolescents self-identified as LGBQ+. Compared to heterosexual adolescents, LGBQ+ adolescents reported poorer global sleep quality, lower perceived social support, greater peer victimization, childhood victimization, and were more likely to be female (all ps < .001). In a longitudinal, parallel mediation analysis adjusting for baseline age, gender, global sleep quality, and childhood victimization, LGBQ+ adolescents reported higher rates of peer victimization (b=0.262 [0.049], p < .001) and less social support (b=−0.385 [0.146], p = .008) at 6months compared with heterosexual peers, predicting poor global sleep quality (b=0.495 [0.191], p = .010 for peer victimization and b=−0.161 [0.068], p = .018 for social support) at 12months. ConclusionThese findings highlight that sexual minority adolescents face increased risks of peer victimization and reduced social support from peers, which contribute to poorer sleep quality. The findings may guide the development of adolescent sleep interventions that also improve social health and relationships.

Family conflict and less parental monitoring were associated with greater screen time in early adolescence.

The current study investigated the prospective relationships between parental monitoring, family conflict, and screen time across six screen time modalities in early adolescents in the USA. We utilised prospective cohort data of children (ages 10-14 years) from the Adolescent Brain Cognitive Development (ABCD) Study (years baseline to Year 2 of follow-up; 2016-2020; N = 10 757). Adjusted coefficients (B) and 95% confidence intervals (CIs) were estimated using mixed-effect models with robust standard errors. A higher parental monitoring score was associated with less total screen time (B = -0.37, 95% CI -0.58, -0.16), with the strongest associations being with video games and YouTube videos. Conversely, a higher family conflict score was associated with more total screen time (B = 0.08, 95% CI 0.03, 0.12), with the strongest associations being with YouTube videos, video games, and watching television shows/movies in Years 1 and 2. The current study found that greater parental monitoring was associated with less screen time, while greater family conflict was linked to more screen time. These results may inform strategies to reduce screen time in adolescence, such as improving communication between parents and their children to strengthen family relationships.

A naturalistic assessment of the relationship between negative affect and loss of control eating over time following metabolic and bariatric surgery

Disordered eating behavior has been linked to suboptimal weight outcomes following metabolic and bariatric surgery (MBS), thereby threatening the most efficacious treatment for severe obesity. While up to 40% of patients may experience loss of control (LOC) eating following MBS, mechanisms driving this behavior are not fully understood. Preliminary evidence suggests that high levels of negative affect (NA) in the moment prompt LOC eating post-MBS; however, it remains unclear whether this momentary relationship is stable or changes over the first several years following surgery. Consequently, this study examined differences in the prospective relationship between NA and LOC eating severity over time post-MBS using three waves of ecological momentary assessment data collection. Participants (n = 143, 87% female), were asked to rate momentary levels of NA and LOC eating severity on their smartphone ≥5 times/day for 7 days at 1-, 2-, and 3-years post-MBS. Both NA and LOC eating were rated on a 1–5 Likert scale, with higher scores indicating more severe symptoms. NA was within- and between-person centered and used as a prospective predictor of LOC eating severity. Analyses evaluated if time post-MBS moderated the relationship. A generalized linear mixed model demonstrated that higher NA predicted more severe LOC eating at the next signal when centered within- and between-subjects. Time post-MBS moderated the within-NA to LOC eating severity effect, such that the relationship remained unchanged between years 1 and 2, but strengthened between years 2 and 3. Findings suggest that momentary NA becomes a more powerful predictor of LOC eating severity as time passes post-MBS, which has important implications for interventions aimed at reducing LOC eating and promoting optimal weight outcomes in the post-surgical period.

Identifying cognitive, affective, and developmental mechanisms linking threat and deprivation with adolescent psychopathology.

The mechanisms linking early-life adversity with psychopathology over the life-course are complex. In this prospective study, we collectively examined cognitive, affective, and developmental mediators previously found to individually link childhood threat and deprivation experiences to adolescent psychopathology to identify the most potent mechanisms. Data came from a community sample of 227 children (mean child age 11.5 ± 0.5 years, 48.5% female) from the Seattle metro area with recruitment designed to reflect diversity in family income. Candidate mechanisms included self-rated pubertal development and task-measured attention bias to threat, emotion regulation, theory of mind, fear learning, inhibitory control, language ability, reasoning, and reward sensitivity. Using a high-dimensional mediation approach, we determined which mediating pathways linking threat and deprivation to psychopathology persisted after controlling for all candidate mechanisms associated with psychopathology. Models additionally controlled for the child's age, sex, early-childhood emotional and behavioral symptoms, poverty, and maternal depression. Blunted reward sensitivity mediated the prospective relationship between threat and internalizing psychopathology, explaining 17.25% (95% CI 1.08%, 69.96%) of this association. Advanced pubertal development was associated with increases in internalizing and externalizing symptoms (standardized associations of 0.16 (95% CI 0.03, 0.29) and 0.17 (95% CI 0.05, 0.29), respectively), but not with adversity. Although deprivation was strongly related to psychopathology, no mechanisms were empirically identified. In a well-characterized community sample, we isolated reward sensitivity as a robust mediator of the prospective association between early-life threat and adolescent internalizing psychopathology. Interventions aimed at bolstering reward sensitivity may mitigate the impact of early-life threat experiences on internalizing problems.

Body image facets as predictors of muscularity-oriented disordered eating in women: Findings from a prospective study

Muscularity-oriented disordered eating (MODE) is becoming increasingly common among women and is characterized by dietary alterations (e.g., blending meals into liquid form to increase caloric intake) aimed towards gaining lean muscle. In light of the mental health risks associated with these pathological eating behaviors, understanding factors that influence women’s engagement in MODE is essential for preventative efforts and for informing etiological models. Body image is a possible factor that may influence MODE in light of evidence of cross-sectional associations and its importance as a key risk factor for thinness-oriented disordered eating. However, research is yet to test for prospective relationships between the various components of body image (i.e., body dissatisfaction, body appreciation) and MODE, which was the aim of this study. Adult women completed the online study measures at baseline (Time 1 [T1]; n = 1760) and three-month follow-up (Time 2 [T2]; n = 1208). A series of univariate regressions revealed that all body image facets (i.e., preoccupation, overvaluation, dissatisfaction, body image appreciation and feeling fat) at T1 significantly predicted MODE at T2. However, multivariable models revealed that only preoccupation and body appreciation uniquely predicted MODE at T2, with a positive relationship observed for preoccupation and a negative one for body appreciation. This is the first study to establish temporal relationships between distinct body image facets and MODE. Pending replication, findings highlight possible targets for addressing MODE in women.

Longitudinal associations between parents' job characteristics, parenting, and adolescent academic outcomes

AbstractObjectiveThis study sought to understand the prospective relationship between parents' jobs, parenting, and adolescents' subsequent school performance.BackgroundRecent research shows that parents' poor job quality and work–family conflict (WFC) are adversely associated with young people's mental health and socioemotional well‐being, with much less known about impacts on adolescents' academic outcomes.MethodWe used data from a nationally representative Australian cohort study to test a longitudinal model linking parents' job characteristics, WFC, and parenting warmth and irritability in early high school, and adolescents' academic achievement in middle high school. Separate models were run for mothers (N = 2,676) and fathers (N = 2,615), and additional multigroup models examined differences between low‐income and middle‐ and high‐income parents.ResultsFindings suggest that parents' WFC increases parenting irritability, which in turn is adversely associated with academic outcomes, particularly for low‐income mothers. Findings also showed that low‐income fathers' WFC was directly associated with poorer academic outcomes.ConclusionParents' WFC in early high school may affect adolescents' achievement in middle high school, with some risks compounded for low‐income households.ImplicationsThis study is among the first to establish a relationship between parents' WFC and adolescents' academic performance and highlights the importance of parents' job resources in supporting adolescent academic outcomes.

Screen time and mental health: a prospective analysis of the Adolescent Brain Cognitive Development (ABCD) Study

BackgroundDespite the ubiquity of adolescent screen use, there are limited longitudinal studies that examine the prospective relationships between screen time and child behavioral problems in a large, diverse nationwide sample of adolescents in the United States, which was the objective of the current study.MethodsWe analyzed cohort data of 9,538 adolescents (9–10 years at baseline in 2016–2018) with two years of follow-up from the Adolescent Brain Cognitive Development (ABCD) Study. We used mixed-effects models to analyze associations between baseline self-reported screen time and parent-reported mental health symptoms using the Child Behavior Checklist, with random effects adjusted for age, sex, race/ethnicity, household income, parent education, and study site. We tested for effect modification by sex and race/ethnicity.ResultsThe sample was 48.8% female and racially/ethnically diverse (47.6% racial/ethnic minority). Higher total screen time was associated with all mental health symptoms in adjusted models, and the association was strongest for depressive (B = 0.10, 95% CI 0.06, 0.13, p < 0.001), conduct (B = 0.07, 95% CI 0.03, 0.10, p < 0.001), somatic (B = 0.06, 95% CI 0.01, 0.11, p = 0.026), and attention-deficit/hyperactivity symptoms (B = 0.06, 95% CI 0.01, 0.10, p = 0.013). The specific screen types with the greatest associations with depressive symptoms included video chat, texting, videos, and video games. The association between screen time and depressive, attention-deficit/hyperactivity, and oppositional defiant symptoms was stronger among White compared to Black adolescents. The association between screen time and depressive symptoms was stronger among White compared to Asian adolescents.ConclusionsScreen time is prospectively associated with a range of mental health symptoms, especially depressive symptoms, though effect sizes are small. Video chat, texting, videos, and video games were the screen types with the greatest associations with depressive symptoms. Future research should examine potential mechanisms linking screen use with child behavior problems.

Age-Dependent Relationship between Self-Esteem and Depressive Symptoms in Korean Adolescents: a Meta-Analysis of Longitudinal Studies.

Self-esteem is a powerful protective factor against depressive symptoms, with cognitive vulnerability theory suggesting that early self-esteem more strongly predicts later depressive symptoms than vice versa. While some meta-analyses have examined these relationships, limited knowledge exists on the prospective relationship between self-esteem and depressive symptoms, particularly how it changes with age. This study conducted a longitudinal meta-analysis of nine studies (20,733 participants) on the prospective relationship between self-esteem and depressive symptoms in Korean children and adolescents. Relationships were analyzed by integrating the effect sizes of 22 zero-order correlations and 17 partial correlations and examining age-related changes. The results indicated significant negative correlations in both zero-order and partial correlations. Age-related changes showed a reverse U-shape trend in partial correlations, with the strongest negative association during childhood, weakening until age 14, and then strengthening again. Moderator analysis revealed no significant effect size variation based on publication type or gender proportion, but more recent birth cohorts exhibited a stronger negative relationship in zero-order correlations. Significant differences were also found based on the measurement instrument of depressive symptoms. These findings highlight the importance of tailored interventions to enhance self-esteem and mitigate depressive symptoms, extending the cognitive vulnerability model within Korea's cultural context and providing insights into Korean youth mental health.

8450 Accelerometer-based Sedentary Time and Physical Activity with the Risk of Severe Liver Steatosis and Liver Cirrhosis in 2684 Children: A 13-Year Longitudinal and Mediation Study

Abstract Disclosure: A.O. Agbaje: None. Background: Non-alcoholic fatty liver diseases have been associated with physical inactivity in adults. However, long-term evidence on the prospective relationship of accelerometer-measured sedentary time (ST), light physical activity (LPA), and moderate-to-vigorous PA (MVPA) with liver steatosis and fibrosis and changes in liver enzymes in a large paediatric population is scarce. Hypothesis: It was hypothesized that increased ST from childhood through young adulthood would increase the risk of severe liver steatosis and cirrhosis and worsen liver enzymes, whereas engaging in LPA and MVPA would reduce the risk. Methods: From the Avon Longitudinal Study of Parents and Children (ALSPAC), UK birth cohort, 2684 children aged 11 years who had at least one follow-up time-point accelerometer-measured ST, LPA, and MVPA over a period of 13 years, and liver indices and enzymes measures at age 24 years clinic visit were included. Liver steatosis and fibrosis were assessed by transient elastography (FibroScan 502 Touch) and categorized as fibrosis stage F0-F4 and steatosis grade (S0-S3) at age 24 years. Alanine aminotransferase (ALT), aspartate aminotransferase (AST), and γ-glutamyl transferase (GGT) were assayed at ages 17 and 24 years. Longitudinal associations were examined using generalized linear mixed-effect models, while mediation analyses were conducted with structural equation models. Results: Among 2684 children (mean [SD] age, 11.75 [0.24] years; 1537 [57.3%] females]), ST increased from 6 hours/day in childhood to 9 hours/day in young adulthood, while LPA decreased from 6 hours/day to 3 hours/day and MVPA was relatively stable at 50 minutes/day. The prevalence of liver cirrhosis [F4, ≥11·7 kPa] and severe liver steatosis [S3, controlled attenuation parameter value ≥280 dB/m] is 0.3 and 10%, respectively. Cumulative 1-minute/day increase in ST from ages 11-24 years was associated with higher odds of liver cirrhosis (odds ratio 1.004 [95% CI 1.002 - 1.005] p&amp;lt;0.001) and severe liver steatosis (1.001 [1.001 - 1.002] p=0.002) at age 24 years. Increased ST from childhood was directly associated with increased ALT, AST, and GGT from ages 17 - 24 years. Cumulative 1-minute/day LPA was associated with lower odds of liver cirrhosis (0.990 [0.990 - 0.991] p&amp;lt;0.001) and severe liver steatosis (0.999 [0.998 - 0.999] p&amp;lt;0.001) at age 24 years, as well as decreased liver enzymes. Cumulative 1-minute/day MVPA was associated with associated with lower odds of severe liver steatosis (0.996 [0.994 - 0.998] p&amp;lt;0.001) but not liver cirrhosis at age 24 years. MVPA effect on lowering liver steatosis was significantly suppressed (64% suppression) by increased fat mass. Conclusions: Increasing LPA, sustaining MVPA, and decreasing ST from childhood may independently attenuate and reverse the risk of severe liver steatosis and cirrhosis by young adulthood. Presentation: 6/1/2024

Childhood language development and alexithymia in adolescence: an 8-year longitudinal study.

Alexithymia (difficulties identifying and describing feelings) predicts increased risks for psychopathology, especially during the transition from childhood to adolescence. However, little is known of the early contributors to alexithymia. The language hypothesis of alexithymia suggests that language deficits play a primary role in predisposing language-impaired groups to developing alexithymia; yet longitudinal data tracking prospective relationship between language function and alexithymia are scarce. Leveraging data from the Surrey Communication and Language in Education cohort (N = 229, mean age at time point 1 = 5.32 years, SD = 0.29, 51.1% female), we investigated the prospective link between childhood language development and alexithymic traits in adolescence. Results indicated that boys with low language function at ages 4-5 years, and those who later met the diagnostic criteria for language disorders at ages 5-6 years, reported elevated alexithymic traits when they reached adolescence. Parent-reported child syntax abilities at ages 5-6 years revealed a dimensional relationship with alexithymic traits, and this was consistent with behavioral assessments on related structural language abilities. Empirically derived language groups and latent language trajectories did not predict alexithymic traits in adolescence. While findings support the language hypothesis of alexithymia, greater specificity of the alexithymia construct in developmental populations is needed to guide clinical interventions.

Habitualness, reward and external constraints: Exploring the underlying influences of daily water intake using the Situated Assessment Method2.

Understanding what facilitates and hinders water drinking is crucial to inform interventions for preventing underhydration. Using the Situated Assessment Method2, we extended previous research by examining what influences water drinking in daily life. We studied 213 UK adults, assessing 13 potential predictors (e.g. thirst, availability of other drinks) of their typical water intake across 10 everyday situations (e.g. during work, dinner). Participants then reported their actual water intake in these situations over three alternating days during a 1-week follow-up. We evaluated the variability of water intake and its influences across individuals and situations and the prospective relationship between these influences and water intake. The 13 identified predictors explained substantial proportions of variation in water intake. Factors like habitualness (e.g. subjective effort), self-relevance (e.g. health consciousness) and immediate feedback (e.g. taste) were positively associated with water intake. However, the influence of these factors varied significantly across individuals and situations. Our results suggest that various interrelated predictors facilitate and hinder water drinking behaviour, emphasising the importance of using comprehensive behaviour theories to inform research in this domain. They also align with growing evidence that reward may regulate habitual behaviour.

Change processes associated with functional improvement in a web-based version of Skills Training in Affective and Interpersonal Regulation (webSTAIR) for trauma-exposed veterans.

In spite of the evidence that both symptom reduction and functional improvement are important for supporting recovery from trauma, psychotherapy process research has largely focused on mechanisms of symptom reduction. A better understanding of how change occurs in treatments that emphasize functional improvement rather than trauma processing is critical for optimizing effective, patient-centered care. This study involved secondary analysis of data collected in three multisite trials of a 10-module web-based version of Skills Training in Affective and Interpersonal Regulation, a skills-focused transdiagnostic intervention. The sample included 314 trauma-exposed veterans (38% male; 64% non-Hispanic White) who screened positive for elevated symptoms of posttraumatic stress disorder and/or depression. Latent change score modeling examined prospective relationships between changes from pre-to-mid and mid-to-post treatment in four potential mechanisms (emotion regulation, interpersonal problems, posttraumatic stress disorder symptoms, and depression symptoms) and the association of these changes with overall functional improvement (at posttreatment and follow-up). Emotion regulation change during the first half of treatment predicted interpersonal and symptom improvements during the second half of treatment, but not vice versa. Changes in each potential mechanism were uniquely associated with functional improvement and together statistically accounted for 78% additional variance in functional improvement beyond what was associated with baseline functioning and covariates. Results support emotion regulation as an early mechanism of transdiagnostic therapeutic change in web-based version of Skills Training in Affective and Interpersonal Regulation and highlight the relevance of all four potential mechanisms to functional improvement. The study contributes to an understanding of how change occurs in skills-focused interventions for trauma-exposed individuals. (PsycInfo Database Record (c) 2024 APA, all rights reserved).