Tree species in the genus Prosopis have been recognized as valuable for reforestation in the world's semi-arid regions. Self-incompatibility and the mandatory outcrossing of Prosopis species results in a high degree of genetic variability, resulting in a need for asexual propagation of trees with desirable characteristics. Five species from Prosopis section Algarobia (Prosopis articulata, Prosopis chilensis, Prosopis juliflora, Prosopis glandulosa var. torreyana and Prosopis alba) and one species from the section Strombocarpa (Prosopis tamarugo) were reciprocally grafted to each other to determine their graft compatibility. All species from Prosopis section Algarobia were graft compatible with each other. Graft compatibility barriers apparently exist between P. tamarugo from the section Strombocarpa and the species from section Algarobia. A simple and effective method for grafting Prosopis has been identified.