British Journal of Clinical PharmacologyVolume 13, Issue 4 p. 571-574 Free Access Early kinetics of intravenous propranolol. TC Fagan, TC FaganSearch for more papers by this authorT Walle, T WalleSearch for more papers by this authorUK Walle, UK WalleSearch for more papers by this authorEC Conradi, EC ConradiSearch for more papers by this authorG Harmon, G HarmonSearch for more papers by this authorTE Gaffney, TE GaffneySearch for more papers by this author TC Fagan, TC FaganSearch for more papers by this authorT Walle, T WalleSearch for more papers by this authorUK Walle, UK WalleSearch for more papers by this authorEC Conradi, EC ConradiSearch for more papers by this authorG Harmon, G HarmonSearch for more papers by this authorTE Gaffney, TE GaffneySearch for more papers by this author First published: April 1982 https://doi.org/10.1111/j.1365-2125.1982.tb01424.xCitations: 6AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat REFERENCES GIBALDI, M. & PERRIER, D. (1975). Pharmacokinetics. New York: Marcel Dekker, Inc. HESSE, B., HANSEN, J.F., STEINESS, E., EHLERS, D. & ANDERSEN, J.D. (1979). Temporal relationship between cardiac performance and myocardial uptake of dl-propranolol in man. Clin. exp. Pharmac. Physiol, 6, 241– 248. KATES, R.E. & JAILLON, P. (1980). A model to describe myocardial drug disposition in dog. J. Pharmac. exp. Ther., 214, 31– 36. LOO, J.C.K. & RIEGELMAN, S. (1970). Assessment of pharmacokinetic constants from postinfusion blood curves obtained from I.V. infusion. J. pharm. Sci., 59, 53– 55. PRUETT, J.K., WALLE, T. & BAGWELL, E.E. (1977). Association of in vivo and in vitro propranolol levels in canine Purkinje fibers with antiarrhythmic effects. J. Pharmac. exp. Ther., 202, 45– 54. RIVA, E., LATINI, R., CREMONESI, A., ZACA, F. & PAGLIARANI, P. (1980). Time course of plasma levels and electrophysiologic effects of propranolol in man. J. cardiovasc. Pharmac., 2, 707– 714. ROUTLEDGE, P.A. & SHAND, D.G. (1979). Clinical pharmacokinetics of propranolol. Clin. Pharmacokin., 4, 73– 90. SCHAMROTH, L. (1966). Immediate effects of intravenous propranolol on various cardiac arrhythmias. Am. J. Cardiol., 18, 438– 443. WALLE, T., CONRADI, E.C., WALLE, U.K., FAGAN, T.C. & GAFFNEY, T.E. (1978a). The predictable relationship between plasma levels and dose during chronic propranolol therapy. Clin. Pharmac. Ther., 24, 668– 677. WALLE, T. CONRADI, E.C., WALLE, U.K., FAGAN, T.C. & GAFFNEY, T.E. (1979a). Naphthoxylactic acid after single and long-term doses of propranolol. Clin. Pharmac. Ther., 26, 548– 554. WALLE, T., CONRADI, E.C., WALLE, U.K., FAGAN, T.C & GAFFNEY, T.E. (1980). 4-Hydroxypropranolol and its glucuronide after single and long-term doses of propranolol. Clin. Pharmac. Ther., 27, 23– 31. WALLE, T., FAGAN, T.C., CONRADI, E.C., WALLE, U.K. & GAFFNEY, T.E. (1979b). Presystemic and systemic glucuronidation of propranolol. Clin. Pharmac. Ther., 26, 167– 172. WALLE, T., WALLE, U.K., BRIDGES, D.R., CONRADI, E.C. & GAFFNEY, T.E. (1978b). Quantitative GC-MS of propranolol. a key to an improved understanding of the relationship between plasma concentrations and dose. Clin. Chem., 24, 991. WOOD, M., SHAND, D.G. & WOOD, A.J.J. (1979). Altered drug binding due to the use of indwelling heparinized cannulas (heparin lock) for sampling. Clin. Pharmac. Ther., 25, 103– 107. Citing Literature Volume13, Issue4April 1982Pages 571-574 ReferencesRelatedInformation