Proportion Of Radiation Therapy Research Articles

АНАЛИЗ ЭФФЕКТИВНОСТИ ПРИМЕНЕНИЯ КЛЕТОЧНОЙ ТЕРАПИИ ПРИ ЛЕЧЕНИИ МЕСТНЫХ ЛУЧЕВЫХ ПОРАЖЕНИЙ

Every year the proportion of radiation therapy as an independent method of radical treatment of cancer patients is increasing. Exposure to radiation as a result of medical treatment can lead to the development in patients of local radiation injuries (LRJ) (radiation reactions) on the skin and surrounding tissues. Today, there is no standard treatment for LRJ, known methods are ineffective In this regard, research aimed at finding effective methods of treatment leading to accelerated wound healing, a decrease in inflammation and a decrease in fibrosis is relevant. In recent years, there has been an active study of the effectiveness of the use of cell therapy, including mesenchymal stem cells, their cell products, minimally manipulated cell products, etc., in complex therapy for local radiation injuries. In the presented literature review, the effectiveness of the use of cellular products in local radiation damage to the skin caused by sources of ionizing radiation is considered. Bibliographic searches of works were carried out on the basis of the PubMed portal, published in the period from 2015 to August 2020.

Trends of risk classification and primary therapy for Japanese patients with prostate cancer in Nara Uro-Oncological Research Group (NUORG)–a comparison between 2004-2006 and 2007-2009

BackgroundTo assess the trends of risk classification and primary therapy in Japanese patients who were diagnosed with prostate cancer between 2004-2006 and 2007-2009.MethodsA total of 4752 patients who were newly diagnosed with prostate cancer at Nara Medical University and its 23 affiliated hospitals between 2004 and 2009 were enrolled. The differences in risk classification and primary therapy were compared in patients who were newly diagnosed between 2004-2006 (prior period) and 2007-2009 (latter period).ResultsThe proportion of patients with a high or greater risk significantly decreased in the latter period compared to the prior period (p < 0.001). The proportion of primary androgen deprivation therapy (PADT) was 50% in the prior period, and 40% in the latter period. On the other hand, the proportion of radiation therapy was 14% in the prior period, but 24% in the latter period. The proportion of radical prostatectomy was the same in the two periods (30%). The primary therapy was significantly different between the two periods (p < 0.001).ConclusionsHigher risk patients significantly decreased in the latter period compared to the prior period. The use of PADT also significantly decreased in the latter period. However, there were still higher risk patients in Japan, and the use of PADT was still common in patients with localized prostate cancer or locally advanced prostate cancer in Japan.