Abstract Citizen Science (CS) stands as a beacon of hope in the fight against inequalities in adolescent health, revolutionizing scientific research by involving individuals from diverse backgrounds. Unlike traditional methods, CS transcends academic boundaries, fostering inclusivity and collaboration irrespective of age, nationality, or social status. This approach has gained momentum in adolescent health research, empowering young people as co-researchers from project inception, thereby reducing disparities in health knowledge and access. Studies demonstrate its efficacy in enhancing empowerment and health literacy among participants. YouthChronic is an example of how CS can mitigate health inequalities among adolescents. The project ensures active participation in every research stage by engaging adolescents with chronic conditions as citizen scientists. Open-ended questions facilitate detailed responses, while participation in analysis and dissemination enhances their research involvement and sense of ownership. Through initiatives like YouthChronic, CS is reshaping the research landscape, making it more relevant and impactful to bridge the inequality gap. Young Citizen Scientists’ views on their participation: “As part of YouthChronic, we felt like our experiences with chronic conditions were finally being heard. The researchers were cool-they listened to us, let us be flexible with our participation, and even taught us some research skills. Learning from other peers’ experiences made us feel less alone and gave us new insights. But it’s frustrating that we’re limited by resources. We have big ideas, like running an advocacy campaign, but we need funding to make them happen”. In conclusion, by actively involving adolescents in the scientific process through CS initiatives like YouthChronic, we can reduce inequalities in adolescent health, empower marginalized voices, and pave the way for a brighter, more inclusive future in scientific exploration and discovery.