The article analyzes the way in which the so-called "antipositivist reaction" was deployed in the Argentine philosophical field at the beginning of the twentieth century and its relationship with the politicization and professionalization of philosophy. The paper reconstructs the controversy over the definition of philosophy established by the group of young people who in 1917 founded in Buenos Aires the Colegio Novecentista and the Cuadernos (1917-1919) with whom they defended socialist scientism and met around the Journal of Philosophy and its director José Ingenieros. Inscribed in intellectual history, this reconstruction attends to the history of the book and the edition to illuminate the material channels that made possible the circulation of the antipositivist reaction and offers new information about the initial trajectory of intellectuals who were relevant both in the philosophical and literary field of twentieth-century Argentina.